stage 4 non small cell lung cancer prognosis 2010
Báo cáo hóa học: " Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer" pdf
Ngày tải lên :
18/06/2014, 16:20
... Non- small- cell lung cancer harbouring mutations in the EGFR
kinase domain. Clin Transl Oncol 2010, 12:75-80.
9. Gazdar AF: Activating and resistance mutations of EGFR in non- small- cell
lung cancer: ... 70 343 1 94 340 60
Age, years
range 36-85 42 -83 27-88
median 64 67 59.9
Sex
male 28 31 36
female 50 30 34
Ethnicity
Caucasian 78 61 0 0 0
Asian 0 0 70 343 60
Smoking history
smokers 33 37 41
non- smokers ... lung cancer patients.
Methods: EGFR mutation status was analyzed by DNA assays, and compared with IHC results in five non- small- cell
lung cancer (NSCLC) cell lines and tumor samples from 78 stage...
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Báo cáo khoa học: "Clinical outcomes of stereotactic body radiotherapy for stage I non-small cell lung cancer using different doses depending on tumor size" ppsx
Ngày tải lên :
09/08/2014, 09:20
... 65 2 47 16
1 48 0 31 17
2110 74
Tumor size (mm)
Range (median) 12-55 (27) 12, 14 15- 34 ( 24) 31-55 (35)
Operability
Operable 40 2 27 11
Non- operable 84 0 58 26
Histology
Adenocarcinoma 66 2 46 18
Squamous ... early-
stage non- small- cell lung cancer: clinical implications. Radiother Oncol
2010, 94: 1-11.
27. Chen Y, Guo W, Lu Y, Zou B: Dose-individualized stereotactic body
radiotherapy for T1-3N0 non- small ... 70
all patients
stage IA patients treated with 48 Gy in 4 fractions
stage IB patients treated with 52 Gy in 4 fractions
all patients
stage IA patients treated with 48 Gy in 4 fractions
stage IB patients...
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Báo cáo khoa học: " Comparison of outcomes in patients with stage III versus limited stage IV non-small cell lung cancer" docx
Ngày tải lên :
09/08/2014, 09:20
... iotherapy, Oligometastases, Non- Small Cell Lung Cancer
Background
Non- small cell lung cancer (NSCLC) is the leading
cause of cancer mortality in the United States [1].
Patients with stage IV NSCLC typically ... of 7
RESEARC H Open Access
Comparison of outcomes in patients with stage III
versus limited stage IV non- small cell lung cancer
Praveena Cheruvu
1
, Su K Metcalfe
1
, Justin Metcalfe
1
, Yuhchyau ... limited metastatic stage
IV. Fifty-five of the 94 patients with initial stage III
NSCLC ( 74% ) developed radiographically apparent
metastases, of whom 44 developed limited metastatic
stage IV disease...
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Báo cáo khoa học: "Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL study" pps
Ngày tải lên :
09/08/2014, 09:22
... body radiotherapy for stage I
non- small cell lung cancer. Radiother Oncol 2007, 85 :42 9 -43 4.
39. Sinha B, McGarry RC: Stereotactic body radiotherapy for bilat-
eral primary lung cancers: the Indiana ... surgery in patients with
operable lung cancer.
A randomized phase III trial of Radiosurgery Or Surgery
for operable Early stage (stage 1A) non- small cell Lung
cancer (ROSEL, ClinicalTrials.gov ... Phys 2007, 66:1120-11 24.
40 . Haasbeek CJ, Senan S, Smit EF, Paul MA, Slotman BJ, Lagerwaard FJ:
Critical review of nonsurgical treatment options for stage I
non- small cell lung cancer. Oncologist...
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- 0
Báo cáo khoa học: " Stereotactic, single-dose irradiation of stage I non-small cell lung cancer and lung metastases" docx
Ngày tải lên :
09/08/2014, 10:21
... peripheral stage I
non- small cell lung cancer. Lung Cancer 1999, 26:137- 142 .
23. Slotman BJ, Antonisse IE, Njo KH: Limited field irradiation in
early stage (T1-2N0) non- small cell lung cancer. Radiother
Oncol ... not for citation purposes)
inoperable non- small cell lung cancer without mediastinal
involvement (clinical stage N0, N1). Strahlenther Onkol 1996,
172 :48 9 -49 5.
22. Hayakawa K, Mitsuhashi N, Saito ... stage I non- small cell lung cancer using a novel irradiation
technique: patient self-controlled breath-hold and beam
switching using a combination of linear accelerator and CT
scanner. Lung Cancer...
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Báo cáo khoa học: " Absence of toxicity with hypofractionated 3-dimensional radiation therapy for inoperable, early stage non-small cell lung cancer" pot
Ngày tải lên :
09/08/2014, 10:21
... as lung cancer. It is more convenient for the patients and reduces health care costs.
This study reports our results on patients with medically inoperable, early stage, non- small cell lung
cancer ...
therapy for inoperable, early stage non- small cell lung cancer
Sergio L Faria*
1
, Luis Souhami
1
, Lorraine Portelance
1
, Marie Duclos
1
,
Te Vuong
1
, David Small
2
and Carolyn R Freeman
1
Address: ... hypofractionated radiation therapy
is an attractive option for patients with early stage non-
small cell lung cancer (NSCLC) who are not surgical can-
didates. Although primarily appealing for...
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báo cáo hóa học:" Randomized phase II study with two gemcitabine- and docetaxel-based combinations as first-line chemotherapy for metastatic non-small cell lung cancer" docx
Ngày tải lên :
18/06/2014, 15:20
... (B).
0 4 8 121620 242 8323 640 444 852
Weeks
0
0.2
0 .4
0.6
0.8
1
TTP
Patients Events (%)
Arm A 35 33 ( 94. 3)
Arm B 34 32 ( 94. 1)
A
0 4 8 12 16 20 24 28 32 36 40 44 48 52
Weeks
0
0.2
0 .4
0.6
0.8
1
Survival
Patients ... Estimating the world cancer
burden: Globocan 2000. Int J Cancer 2001, 94: 153-156.
2. Non- small Cell Lung Cancer Collaborative Group: Chemotherapy
in non small cell lung cancer: a meta-analysis ... 14 (35) 12 (29.3)
Other NSCLC 4 (10) 6 ( 14. 6)
Site of disease
Lung ± lymph nodes 14 (35) 14 ( 34. 1)
Lung and 1 metastatic site 12 (30) 15 (36.6)
Lung and ≥ 2 metastatic sites 9 (22.5) 10 ( 24. 4)
Extra-pulmonary...
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Báo cáo hóa học: "Prognostic Impact of MiR-155 in Non-Small Cell Lung Cancer Evaluated by in Situ Hybridization" pot
Ngày tải lên :
18/06/2014, 16:20
... 138 41 47 47
Moderate 144 43 190 64
Well 53 16 NR 68
Surgical procedure 0.0 04
Lobectomy + Wedge* 243 73 190 61
Pneumonectomy 92 27 37 47
Pathological stage <0.001
I 157 47 190 71
II 136 41 ... MiR-155 in Non- Small Cell
Lung Cancer Evaluated by in Situ Hybridization
Tom Donnem
1,2*
, Katrine Eklo
3 ,4
, Thomas Berg
3 ,4
, Sveinung W Sorbye
3 ,4
, Kenneth Lonvik
3 ,4
, Samer Al-Saad
3 ,4
,
Khalid ... after
complete resection of non- small cell lung carcinoma. Cancer Res 2010,
70:8288-98.
19. Goldstraw P:
The 7th Edition of TNM in Lung Cancer: what now? J Thorac
Oncol 2009, 4: 671-3.
20. Sandler A,...
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báo cáo hóa học: " Health state utilities for non small cell lung cancer" pot
Ngày tải lên :
18/06/2014, 19:20
... Staging of small cell
and non- small cell lung cancer. University of Iowa Virtual Hos-
pital; 1999.
6. Hopwood P, Stephens RJ: Symptoms at presentation for treat-
ment in patients with lung cancer: ... Big Lung Trial in Non- Small- Cell Lung cancer.
Journal of Clinical Oncology 2005, 30: 741 7- 742 7.
12. Silvestri G, Pritchard R, Welch HG: Preferences for chemother-
apy in patients with advanced non- small ... [ 34] . Osoba et al. [ 34] studied the stated pref-
erences of 40 0 patients with either breast, colorectal or
NSCLC and in either early stages (stage I or II) or late
stages (stage III or IV) of cancer. ...
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Báo cáo toán học: "Molecular Predictors of EGFR-TKI Sensitivity in Advanced Non–small Cell Lung Cancer" ppsx
Ngày tải lên :
08/08/2014, 17:20
... gefitinib in non- small cell lung cancer
cell lines. Mol Cancer Res. 2006; 4( 8): 521-8.
102. Taguchi F, Solomon B, Gregorc V, et al. Mass spectrometry to
classify non- small- cell lung cancer patients ... the leading cause of cancer death world-
wide (1). Lung cancer is generally classified into two
histological types, small cell lung cancer (SCLC) and
non small cell lung cancer (NSCLC).
NSCLC ... in non- small
cell lung cancer Is correlated with survival. Clin Cancer Res.
2001; 7(7): 1850-5.
93. Cappuzzo F, Gregorc V, Rossi E, et al. Gefitinib in pretreated
non- small- cell lung cancer...
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Báo cáo khoa học: "Pathological complete response induced by first-line chemotherapy with single agent docetaxel in a patient with advanced non small cell lung cancer" pptx
Ngày tải lên :
09/08/2014, 03:21
... induced by
first-line chemotherapy with single agent
docetaxel in a patient with advanced non small
cell lung cancer
Ferdinando Riccardi
1*
, Giuseppe Di Lorenzo
1
, Carlo Buonerba
1
, Guglielmo Monaco
2
, ... Carteni’
1
Abstract
Background: Defining the optimal treatment for patients with inoperable non small cell lung cancer (NSCLC),
presenting with metastatic mediastinal lymph nodes, is challenging. Nevertheless, ... few cycles should not
automatically discourage to continue treatment.
Introduction
In non- small cell lung cancer (NSCLC), mediastinal
lymphnode involvement comprises a wide spectrum of
severity....
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Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot
Ngày tải lên :
09/08/2014, 08:23
... = 4. 64
0.011
V40 8.20% (3.29-13.61%)
= 5.91, SD = 2 .48 = 9.26, SD = 3.75
0.015
V45 7 .42 % (2.73-10.99%)
= 4. 41, SD = 2.25 = 6. 54, SD = 3 .47
0.007
V50 7.07%(1. 94- 8.82%)
= 3.15, SD = 1. 94 = 4. 89, ... = 2 .40
0.001
V5 58.73% (32.89-97.65%)
= 58 .43 , SD = 16.57 = 69.23, SD = 12 .47
0.006
V10 42 .16%(25.28-83. 34% )
= 41 .13, SD = 12.69 = 52 .42 , SD = 11.05
0.001
V15 29.53%(16 .46 -58.51%)
= 28. 94, ... limited
stage small cell lung cancer. Int J Radiat Oncol Biol Phys 1999, 43 :39 -45 .
31. Rancati T, Ceresoli GL, Gagliardi G, Schipani S, Cattaneo GM: Factors
predicting radiation pneumonitis in lung...
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Báo cáo khoa học: " Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in non-small cell lung cancer" potx
Ngày tải lên :
09/08/2014, 09:22
... (IAEA)
consultants' meeting on elective nodal irradiation in lung
cancer: non- small cell lung cancer (NSCLC). Int J Radiat Oncol
Biol Phys 2008, 72(2):335- 342 .
6. Therasse P, Arbuck SG, Eisenhauer EA, Wanders ... in
Stage III non- small cell lung cancer? An analysis of recur-
rences in a phase II study of induction chemotherapy and
involved-field radiotherapy. Int J Radiat Oncol Biol Phys 2002,
54( 4):999-1006.
10. ... of fail-
ure for non- small- cell lung cancer with position-emission
tomography/computed tomography defined target delinea-
tion. Int J Radiat Oncol Biol Phy 2007, 69: 140 9- 141 6.
14. Chang DT, Zlotecki...
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Báo cáo khoa học: " Evalution of surface-based deformable image registration for adaptive radiotherapy of non-small cell lung cancer (NSCLC)" pptx
Ngày tải lên :
09/08/2014, 10:20
... AP)
62.1 2 70 DDP +
Navelbine
Pat #4 56,8 T3 N1 IIIA SSC 14 109.1 2 62 DDP +
Navelbine
Pat #5 49 ,0 T2 N2 IIIA Adeno Ca 11 147 .2 2 66 DDP +
Navelbine
Pat #6 34, 9 T4 N2 IIIB Adeno Ca < 5 160.1 ... during exter-
nal beam radiotherapy for non- small- cell lung cancer: obser-
vations on tumor regression during treatment. Int J Radiat
Oncol Biol Phys 2005, 63:10 24- 1028.
10. Yan D, Vicini F, Wong J, ... relationship
between the target and the parotid glands [8]. Similar
findings were made for non- small- cell lung cancer
(NSCLC), where a continuous tumor regression during
radiotherapy was observed [9].
This...
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Báo cáo khoa học: " Accelerated high-dose radiotherapy alone or combined with either concomitant or sequential chemotherapy; treatments of choice in patients with Non-Small Cell Lung Cancer" pps
Ngày tải lên :
09/08/2014, 10:21
... in
patients with locally advanced non- small- cell lung cancer. A
phase II trial conducted by the Groupe Francais de Pneumo-
Cancerologie (GFPC). Lung Cancer 2005, 47 :395 -40 4.
42 . Vokes E, Herndon J, Kelley ... for stage I Nonsmall cell lung carcinoma. Cancer 20 04,
101:1623-1631.
54. Belderbos J, Heemsbergen W, Hoogeman M, Pengel K, Rossi M, Leb-
esque J: Acute esophageal toxicity in non- small cell lung ... unresecta-
ble stage IIIA and B non- small- cell lung cancer. J Clin Oncol
2005, 23:3760-3767.
46 . El Sharouni SY, Kal HB, Battermann JJ: Accelerated regrowth of
non- small- cell lung tumours after...
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