... production and concentrations of MCP-1, ICAM-1, MMP-9 and oxLDL, mean values for all the OXANO concentrations measured during clamping and reperfusion and for the markers sampled before, during and ... correlation between MCP-1 and radical levels and a negative correlation between ICAM-1 and these levels The lack of a positive correlation between radicals and these markers of inflammation, as ... ICAM-1, MMP-9 and oxLDL Blood samples were withdrawn for an analysis of markers of arteriosclerosis together with OXANO samples 1, and 9, i.e before clamping, just before declamping and 15 minutes...
... female reproductive tract and bone by using ArKO mice MATERIALS AND METHODS Materials A standard rodent chow (NMF) was obtained from Oriental Yeast (Tokyo, Japan) BPA and E2 were from Sigma-Aldrich ... Effects of dietary BPA on body weight and uterine weight in wildtype and ArKO mice Body weight (A) and uterine wet weight (B) were measured at months of age Wild-type and ArKO mice were fed chow diet ... Ovaries were collected from wild-type mice fed 0% (A), 0.1% (B) and 1% (C) BPA and from ArKO mice fed 0% (D), 0.1% (E) and 1% (F) BPA and processed for histological analysis The sections were stained...
... (dsDNA), (b) nucleosomes and α-actinin and (c) dsDNA and αCorrelation between binding to (a) nucleosomes and double-stranded DNA (dsDNA), (b) nucleosomes and α-actinin and (c) dsDNA and αactinin Absorbance ... study and to obtain samples, to carry out immunoassays and statistical analyses, to conceive and design the study and to write the final manuscript DPD helped to recruit patients for the study and ... conceive and design the study and to write the final manuscript DAI helped to conceive and design the study All authors read and approved the final manuscript 11 12 13 14 Acknowledgements JJM and...
... articular cartilage Cartilage degeneration results from an imbalance between anabolic and catabolic processes due to the dedifferentiation and apoptosis of chondrocytes and increased synthesis of ... chondrocytes and synoviocytes as well as prostaglandin E2 and proteinases such as the matrix metalloproteinases (MMPs) and aggrecanases [3-5] The aggrecanses and the matrix metalloproteinases are thought ... c-Jun NH2-terminal kinase (JNK) and p38 http://www.journal-inflammation.com/content/5/1/22 [17] The p38 family has four members: α and β which are 75% homologous and γ and δ that are more distantly...
... dura was closed in the standard fashion and gel foam and a dural patch were placed epidurally A subfascial gravity drain was placed No suction was applied, as is the standard procedure following ... debulking was performed and the tumor was excised following resection of the dorsal nerve root from which the capsule was seen to arise The tumor was yellowish-grey and bilobed and was sent for histopathologic ... cm and approximately 150 ml) on the right side, extending into the epidural space and compressing the cord (Figure 2) The blood clot had pushed away the sutured spinous process superiorly and...
... describing discourse markers is a dedicated lexicon that provides a classification of their syntactic, semantic and pragmatic features and characterizes the relationships between similar markers To this ... words we regard as discourse markersand thus are to be included in the lexicon, and determining the lexical entries for these words Finding the "right" set of discourse markers is not an easy task, ... of individual groups of markers, such as [Vander Linden, Martin 1995] for PURPOSE markers Besides, the Linguistics literature offers fine-grained analyses of individual markers, which are far...
... the target side, and translating this information into the appropriate case markersand morphological affixes The key bits of information for us are suffixes and semantic relations, and the vehicle ... Semantic and Suffix Factors: the combination of English suffixes and semantic relations is aligned with Hindi suffixes and case markers я lations from the Universal Networking Language (UNL), and the ... Human evaluators judged the fluency and adequacy, and counted the number of errors in case markersand morphology 6.2 Results Table shows the impact of suffix and semantic factors The models experimented...
... boundaries and discourse markers, and should take advantage of acoustic information For detecting boundary tones, the model of Wightman and Ostendorf (1994) achieves a recall rate of 78.1% and a precision ... language model that incorporates POS tagging and the identification of discourse markers We then augmeat this model with speech repair detection and correction and intonational boundary tone detection ... typically a correspondence between the reparandum and the alteration, and following Bear et al (1992), we annotate this using the labels m for word matching and r for word replacements (words of the...
... an argument) and a set of inflectional affixes which mark aspect, tense and agreement (Andrzejewski, 1968) The forms of the tense and agreement markers vary depending on whether ... have the form gender-root-case, where the gender markers are ‘k-’ (masculine) and ‘t-’ (feminine), and the case markers are ‘-’ (accusative) and ‘u’ (nominative), with spelling rules that collapse ... discourse reasons, and here the +fullForm version is used ((Lecarme, 1995) uses the terms ‘restrictive’ and ‘extensive’ for -fullForm and +fullForm respectively) ‘kau’ to ‘ku’ and ‘kiiu’ to ‘kii’...
... An Introduction to Mathematical Logic and Type Theory, Orlando: Academic Press Inc [Andrews, 2002] Andrews, P.B., 2002 An Introduction to Mathematical Logic and Type Theory, Dordrecht: Kluwer Academic ... investigated three thousand sentences for each temporal marker and discovered the following facts: The semantic and syntactic properties of the phrase accompanying the temporal markers play an important ... λe (S2•S1•e & ending•e < pt_speech()) Figure Dico and rules In composition rules, the symbol ‘→’ stands for syntactic rewriting and ‘
... Translational Medicine 2009, 7:76 IG(K/L)V and IG(K/L)J segments Both for heavy and light chains, the segments involved in V(D)J recombination confer diversity by random and imprecise rearrangement during ... ground in studies indicating that CLL cell growth and survival were favoured through sequential interactions between CD38 and CD31 and between CD100 and plexin B1, the latter expressed by microenvironmental ... [4], and it is more common among patients bearing other poor prognostic factors, such as UM IGHV, or ZAP-70 and CD38 expression [4,10,27,30] TP53 is a transcription factor activated by strand...
... and designed the research; analyzed and interpreted the data; performed statistical analysis, handled funding and supervision and drafted the manuscript RRG, DB, OM, have acquired, analyzed and ... onset and lower levels of the inflammatory biomarkers ICAM-1 and IL-6 at 24 hours Previous studies by our group have reported associations between serum levels of these inflammatory markersand ... interleukin-6 (IL-6) and Intercellular Adhesion Molecule-1 (ICAM-1) as markers of inflammatory response, and matrix metalloproteinase (MMP-9) and cellular fibronectin (cFn) as markers of blood brain...
... 4, 40 and 400 μM of gemcitabine; and 0.6, and 60 μM of taxol Drugs were used at concentrations corresponding to peak plasma levels and were also tested at doses equivalent to one-tenth of and tenfold ... Software (version 4, BioRad) and sequences are listed in Table The standard reaction volume was 25 μl containing μl of cDNA template, × SYBR Green Mix and μM of forward and reverse primers The mixture ... towards the search for molecular and genetic markers involved in proliferation and DNA repair processes that might be predictive of response to both conventional cytotoxic and target therapy drugs [11]...
... suppresses ICV LPS-induced F4-NeuroPs at 10 mg/kg and completely suppresses F4-NeuroP formation and both reduction in dendrite length and reduction in spine density at 100 mg/ kg (Figure 5) GT, an ... there is increased gene transcription and subsequent translation of cytokines and chemokines, prominently including tumor necrosis factor, interleukin-1, and interferons, as well as several enzymes; ... as well as several enzymes; important among these are iNOS and cyclooxygenase (COX-2) that catalyze the formation of NO and prostaglandin (PG) H2, respectively [4] While NO is a potent cell signaling...
... mutant SOD1 limited to motor neurons is insufficient to cause motor neuron degeneration [8,9], and work by Cleveland and co-workers has generated findings, which show that toxicity to motor neurons ... PBS The spinal cord and brain were dissected out and fixed overnight in 4% paraformaldehyde at 4°C, transferred to 30% sucrose and then frozen Lumbar spinal cord, cortical, and brainstem sections ... (A-F) and in motor cortex with OX-42 (G) and OX-6 (H) during Visualization disease Visualization of microglia in midbrain with GSA-I-B4 lectin (A-F) and in motor cortex with OX-42 (G) and OX-6...
... system Band density was quantitated with ImageJ [34] and analyzed as a ratio of GAPDH and a synuclein Results are reported as a percent increase from control TNFa, IL-6, MIP-1a, IL-1b, Ab42, and ... midbrain, and the cerebellum were assessed for levels of pro-inflammatory cytokines/chemokines andmarkers of neurodegenerative disease More specifically, brain region-specific TNFa, IL-6, MIP-1a, and ... exposure elevates subclinical markersand induces AD-like pathology in both the frontal and temporal lobe Figure Subchronic DE Exposure Differentially Regulates Other Cytokines and Chemokines in the...
... Mean with the standard error bars of measured Caspase3, IL6 and TNFa (a), Ca2+, Mg2+ and Ca2+/Mg2+(b), and Na+, K+ and Na+/K+(c) in autistic patients (N = 25) compared to age and gender matching ... Caspase3 and IL6 (positive correlation); (b): Caspase3 and TNFa (positive correlation); (c): Caspase3 and Ca2+ (positive correlation); (d): Caspase3 and K+ (negative correlation); (e): Caspase3 and ... Absolute values of Na+ and Mg2+ recorded the lowest percentage changes recording 13.1% and 5.9% increase, respectively Table and Figure show the significantly positive and negative correlated...
... the spine A spine phantom was measured every week to keep the precision error less than 2% All measurements were completed by one operator T scores of lumbar spine L2 to L4 were obtained and ... years, and the mean weight was 56.7 ± 9.8 kg The prevalence of osteoporosis at lumbar spine increased progressively with age (Figure 1) Of all the women in our sample, 40.4% (T ≤ -2.5) and 61.5% ... = 92) of moderate risk, and 7.3% (n = 16) of high risk, respectively Figure shows the different cutoffs for LS BMD T score by DXA and the categories of low, moderate, and high risk of osteoporosis...
... antigen and both enzymes and the correlation coefficient values were (A; r = 0.44, P value is 0.008) for ALT and (B; r = 0.47, P value is 0.003) for AST And also positive correlation between E1 and ... Anand and Velez, [44] and contradictory to results obtained by Beld et al., [45]; Sabin et al., [17] and Hassan et al., [16] Although it seems conflicting that results of Hassan et al., [16] and ... HCV core Correlation betweenlevels of ALT and AST and E1 antiCorrelation between levels of both HCV core and E1 antigens with the serum levels of ALT and AST Results showed generally positive...
... and designed the research; analyzed and interpreted the data; performed statistical analysis, handled funding and supervision and drafted the manuscript RRG, DB, OM, have acquired, analyzed and ... onset and lower levels of the inflammatory biomarkers ICAM-1 and IL-6 at 24 hours Previous studies by our group have reported associations between serum levels of these inflammatory markersand ... interleukin-6 (IL-6) and Intercellular Adhesion Molecule-1 (ICAM-1) as markers of inflammatory response, and matrix metalloproteinase (MMP-9) and cellular fibronectin (cFn) as markers of blood brain...