somatic genetic alterations and implications for targeted therapies in cancer gist cml lung cancer
Báo cáo hóa học: " Microcirculatory alterations: potential mechanisms and implications for therapy" docx
Ngày tải lên :
21/06/2014, 01:20
... achieved by recruiting and derecruiting capillaries, shutting down or limiting flow in capillaries that are perfusing areas with low oxygen requirements and increasing flow in areas with high ... bacterial peritonitis [5,6,8], in all organs investigated, including the skin, tongue [6], gut [6,7], liver [4], and even the brain [8], and in all species that have been investigated, from rodents ... decrease rolling and adhesion of white blood cells to the endothelium [50] Page of Vitamin C and tetrahydrobiopterin Vitamin C and tetrahydrobiopterin have many important actions, including the correct...
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Environmental barriers to trade of the united states and implications for vietnam
Ngày tải lên :
06/02/2014, 20:27
... Hà Nội Tiếng Anh 13 Adam McCarty (2001), Vietnam in ASEAN, Regional Intergration Process and Challenges, Hanoi 14 Damien J Neven (2000), Evaluating the effects of non-tariff barriers, University ... Unilateralism-Environmental Trade Barriers and the Rising Threat to Prosperity through Trade Website 16 http://www.census.gov/foreign-trade/statistics/index.html 17 http://vietnamese.vietnam.usembassy.gov/ambassador.html ... Góp phần bảo vệ sức khoẻ người tiêu dùng 2.2.3.2 Hiệu mặt sinh thái môi trường Bảo vệ sinh thái môi trường nước Chương trình nhãn sinh thái Green Seal Mỹ có tác dụng việc giảm ô nhiễm môi trường...
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Tài liệu SEXUALITY EDUCATION IN SCHOOLS: THE INTERNATIONAL EXPERIENCE AND IMPLICATIONS FOR NIGERIA pdf
Ngày tải lên :
14/02/2014, 14:20
... contraception and HIV/STI prevention; inadequate teaching materials and training; a scattershot approach to providing specific information that undermines comprehensive student understanding; and a tendency ... education? Inform the debate Accurate and understandable information can defuse conflict and mobilize support for programs by demonstrating the magnitude of adolescent health problems Such information ... “examinable” and others not test students on their achievements in learning the subject matter (Senderowitz, 2000) Training teachers Teacher training is a challenge everywhere, including in developed...
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Tài liệu China’s Economic Rise: History, Trends, Challenges, and Implications for the United States pdf
Ngày tải lên :
20/02/2014, 20:20
... Appetite for Energy China’s rapid economic growth has fueled a growing demand for energy, such as petroleum and coal, and that demand is becoming an increasingly important factor in determining global ... The Chinese government has sharply criticized foreign governments for reporting air quality in China, calling their readings inaccurate and complaining that releasing such data violates international ... role in maintaining that system; and (2) that further economic and trade reforms are the surest way for China to grow and modernize its economy For example, by boosting domestic spending and allowing...
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Unfolding the Future of the Long War - Motivations, Prospects, and Implications for the U.S. Army docx
Ngày tải lên :
06/03/2014, 20:20
... Training and Doctrine Command, Army Capability Integration Center, and was conducted within RAND Arroyo Center’s Force Development and Technology Program RAND Arroyo Center, part of the RAND ... world and cut off from one another In the “Chronic Insurgencies/Instability” trajectory, Ink Blot would be reserved for those insurgencies and areas of instability in which the insurgents are gaining ... mechanical means (including photocopying, recording, or information storage and retrieval) without permission in writing from RAND Published 2008 by the RAND Corporation 1776 Main Street, P.O Box...
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VIETNAM’S EXCHANGE RATE POLICY AND IMPLICATIONS FOR ITS FOREIGN EXCHANGE MARKET, 1986-2009 doc
Ngày tải lên :
07/03/2014, 18:20
... and demand in the market The regime is ‘managed’ in that the exchange rate can move only within a stipulated band, the SBV remains a major participant in the market, and various forms of administrative ... quite passive in taking the role of market-makers in the forward market Indeed, banks may often be relatively slow and cautious in responding to requests for forward quotations Of the 29 forex dealers ... supply and demand Currency options were first introduced by Eximbank into Vietnam’s forex market in 2003 However, trading in this form of derivative products has never really taken off and trading...
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Báo cáo khoa học: "Temporal Context: Applications and Implications for Computational Linguistics" pot
Ngày tải lên :
08/03/2014, 04:22
... 1983-1988 While the acronyms increased in frequency, the expanded forms decreased or remained the same A reasonable conjecture is that in this informal register, the acronyms AI and CS largely replaced ... decline, while the conceptually similar terms machine learning and pattern recognition rank sixth and twelfth among the top rising terms There are social, geographic, and linguistic forces that inuence ... Rising and falling AI terms, 1986-1997 Ă )# We have discovered clear frequency trends over time in several corpora Given this, TTW seems benecial for use in information retrieval, but is in an...
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Gender as a Health Determinant and Implications for Health Education pot
Ngày tải lên :
14/03/2014, 21:20
... productive in terms of furthering science, understanding etiology, and testing promising interventions Gendered Selves To understand the possible causal role that gendered psychological and social ... Figure 1) In this case, there is a correlation between the determinant and the health outcome, and altering the determinant results in a corresponding alteration in the health outcome status Randomized, ... easily inform policy or program intervention options Discovering that hostility causes increased smoking and that smoking has a direct causal impact on early mortality does lend more insight into...
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Credit Score Accuracy and Implications for Consumers December 17, 2002: Consumer Federation of America National Credit Reporting Association docx
Ngày tải lên :
15/03/2014, 07:20
... credit information in consumers’credit reports to make decisions about extending and pricing credit, offering and pricing insurance policies, and providing utility services, rental housing, or ... scoring programs Converting the complex and often conflicting information contained in credit reports into a numerical shorthand is a complex process, and requires a significant number of interpretive ... contain errors, and of what kind Errors of omission (information not being reported by all repositories) and errors of commission (inconsistent information between repositories, or duplicated information...
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Báo cáo khoa học: "Using Leading Text for News Summaries: Evaluation Results and Implications for Commercial Summarization Applications" ppt
Ngày tải lên :
17/03/2014, 07:20
... contained one record for each document This file was analyzed to obtain descriptive information about the test corpus and to compare attributes and ratings We used the Searchable LEAD definition ... Wilson and David Schmeer for reading, rating and assigning attributes to the 2,727 test corpus documents and LEADs I would also like to thank Breck Baldwin, Afsar Parhizgar, David Schmeer and Paul ... a larger scale the results that Brandow et al (1995) suggested for leading text, and to determine whether there are easily definable indicators of where leading text extracts fare poorly as general...
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Báo cáo khoa học: Multidrug efflux pumps: The structures of prokaryotic ATP-binding cassette transporter efflux pumps and implications for our understanding of eukaryotic P-glycoproteins and homologues ppt
Ngày tải lên :
22/03/2014, 21:20
... ATP-binding cassette; NBD, nucleotide-binding domain Soaked into ADP-containing crystals b Contains side chain atoms All other MsbA structures listed are Ca trace only are closed in this conformation, ... the interfaces and also involve the Q-loops and X-loops that are in close proximity to the ATP-binding sites [85,86] The aromatic clusters within the ICLs of CFTR are almost certainly involved in ... (2005) P-glycoprotein substrate binding domains are located at the transmembrane domain ⁄ transmembrane domain interfaces: a combined photoaffinity labelling–protein homology modeling approach Mol...
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Báo cáo khoa học: Structure of a trypanosomatid mitochondrial cytochrome c with heme attached via only one thioether bond and implications for the substrate recognition requirements of heme lyase potx
Ngày tải lên :
23/03/2014, 04:21
... (protein main chain in red) and S cerevisiae iso-1-cytochrome c (Protein Data Bank entry: 1YCC) (in blue) Also shown are the heme ligands (histidine and methionine in each case), the cysteines ... been removed for clarity Thin lines indicate heme axial ligand coordination and hydrogen bonds Sulfur atoms (in methionine and cysteine) are colored yellow, nitrogen blue, oxygen red, and iron purple ... chains that coordinate the heme iron, and the cysteine side chain that forms a thioether bond between heme and protein Also shown is the methyl group of the alanine of the AXXCH heme-binding...
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Economics and National Security: Issues and Implications for U.S. Policy pptx
Ngày tải lên :
23/03/2014, 21:20
... focus on job training and worker retraining programs With record unemployment rates and a changing economy, the workforce may require more job training and worker retraining programs in order to ... higher during the same period (e.g., roughly doubling in Argentina and Romania; tripling in Russia, Israel, Singapore, and Chinese Taipei (Taiwan); and rising more than sevenfold in China).120 ... provides some support for the education and training of workers in certain fields or occupations, such as teaching and science and engineering occupations The Workforce Investment Act (WIA; P.L...
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Long-Term Care for the Elderly with Disabilities: Current Policy, Emerging Trends, and Implications for the Twenty-First Century docx
Ngày tải lên :
28/03/2014, 17:20
... of integrated administration, information, financing, and care management arrangements to help providers work together in minimizing costs while maximizing the long-term health and well-being ... care planning protocols, interdisciplinary care teams, centralized records, and integrated information systems; overarching quality-control systems with a single point of accountability; and flexible ... program for the poor, is the major public program covering long-term care for the elderly and for disabled people of all ages Despite the public’s tremendous interest in, and demand for, care in the...
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Báo cáo khoa học: Regulation of the muscle-specific AMP-activated protein kinase a2b2c3 complexes by AMP and implications of the mutations in the c3-subunit for the AMP dependence of the enzyme docx
Ngày tải lên :
30/03/2014, 08:20
... domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations J Clin Invest 113, 274–284 Kemp BE (2004) Bateman domains and adenosine derivatives form ... with red borders indicating the mutations that have been described in vivo in pigs (V224I and R225Q in c3) or humans (mutations in c2, R225W and R307C in c3), and red letters indicating the mutations ... Ca2+ ⁄ calmodulin-dependent protein kinase b (CAMKKb) [14,15] and transforming growth factor b-activating kinase (TAK1) [16] The three AMPK c-subunit isoforms differ in their N-terminal sequences...
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Biofuel production technologies: status, prospects and implications for trade and development pptx
Ngày tải lên :
01/04/2014, 00:20
... biofuels industries for the transport sector, and there is growing interest in many developing countries for similarly “modernizing” the use of biomass in their countries and providing greater ... few other large developing countries, including India [87] and China There are important roles for Government in fostering the development of biofuels industries in developing countries Given that ... startup in 2009; • 34,000 bpd Chevron project in Nigeria, expected on line in 2009; • 30,000 bpd BP project in Colombia to come on line in 2011; and • 36,000 bpd project in Algeria to come on line in...
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báo cáo hóa học:" Gender and sexuality: emerging perspectives from the heterosexual epidemic in South Africa and implications for HIV risk and prevention" pdf
Ngày tải lên :
20/06/2014, 08:20
... the persistence of gender violence remains a worrying continuity that shapes and binds forms of femininity and masculinity Jewkes and Morrell Journal of the International AIDS Society 2010, 13:6 ... hegemonic masculinity involve sexual and other forms of risk taking These include driving cars fast and dangerously, and heavy alcohol consumption; indeed, social norms around alcohol drinking are such ... individual behaviours In real terms, this means focusing attention on building more gender-equitable and caring masculinities, and less acquiescent femininities In so doing, interventions are needed...
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Báo cáo y học: "Role of regulatory T cells in experimental arthritis and implications for clinical use" potx
Ngày tải lên :
09/08/2014, 06:23
... decreases the infiltrate in joints Furthermore, RA patients relapse shortly after withdrawal of anti-TNF-α [19] and thus, despite the dampening of joint inflammation and the reinstatement of ... whether harnessing CD4+CD25+ Treg will represent a viable therapy for RA and other autoimmune diseases in the future Competing interests The author(s) declare that they have no competing interests ... arthritis and spondyloarthropathies, in which phenotype, distribution and functional studies of CD4+CD25+ Treg have been performed [14–17] In all these studies CD4+CD25+ Treg were detected in the joints...
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Báo cáo y học: "Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking" potx
Ngày tải lên :
09/08/2014, 10:23
... Alcohol intake was reported at least every years and categorized in grams per day Husband's educational level was assessed in 1992 in NHS and 1999 in NHSII, and was included as a proxy for socioeconomic ... factor for RF-positive RA, and that presence of this polymorphism interacts with heavy cigarette smoking in a multiplicative manner These findings contribute to the growing understanding of how genetic ... factor for RA, with risk increasing in proportion to duration and intensity of exposure [30-35] Case-control studies conducted in Sweden, Holland, and North America have identified an interaction...
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Báo cáo y học: "Closure of the NCBI SRA and implications for the long-term future of genomics data storage" doc
Ngày tải lên :
09/08/2014, 22:23
... for archiving short read data, now and in the future? DL: The NIH institutes are investigating alternatives to the SRA for archiving sequence read data for its grantees PF: The EBI will continue ... all? DL: As the performance of next-generation sequencing machines continues to improve in terms of speed, cost, accuracy, and length, and as computational processing continues to improve, the ... submissions In order to cope with the increase in submission numbers, we’re working on extending ENA’s ‘ecosystem’ model with various groups or organizations acting as brokers, or a single submission...
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