0

social stress alters the severity of a virally initiated model of multiple sclerosis

báo cáo hóa học:

báo cáo hóa học: " The burden of multiple sclerosis: A community health survey" pot

Hóa học - Dầu khí

... quantitative baseline estimates of the impact of MS which, in turn, can be used for therapeutic intervention, program and healthcare evaluations The primary aim of this study was to compare the ... [14] At the end of Cycle 1.1 a total of 131, 535 respondents had been surveyed; the overall response rate was 84.7% [14] Approval to access the survey data was obtained from Statistics Canada and ... income was large and would reduce the cohort, social assistance was used as a marker of income To better capture the disease burden associated with MS alone, a subgroup analysis was also performed,...
  • 7
  • 395
  • 0
báo cáo hóa học:

báo cáo hóa học:" The burden of multiple sclerosis: A community health survey" potx

Hóa học - Dầu khí

... quantitative baseline estimates of the impact of MS which, in turn, can be used for therapeutic intervention, program and healthcare evaluations The primary aim of this study was to compare the ... [14] At the end of Cycle 1.1 a total of 131, 535 respondents had been surveyed; the overall response rate was 84.7% [14] Approval to access the survey data was obtained from Statistics Canada and ... income was large and would reduce the cohort, social assistance was used as a marker of income To better capture the disease burden associated with MS alone, a subgroup analysis was also performed,...
  • 7
  • 215
  • 0
Báo cáo y học:

Báo cáo y học: "Complement C3 serum levels in anorexia nervosa: a potential biomarker for the severity of disease" pdf

Báo cáo khoa học

... components of the complement cascade and analyzed the activities of the alternative complement activation pathways [24] Serum levels of C3, Factor B and D, hemolytic activity of the alternative pathway, ... cleavage of C5 via thrombin, thereby bypassing the traditional activation cascade using C3 convertases or C5 convertases [13] As a result, C 5a may be generated via thrombin-mediated coagulation ... PBMC activity in these patients [20] Thus, activated PBMCs and neutrophils may further contribute to alterations of C 3a and C 5a levels bypassing the traditional complement activation cascade There...
  • 6
  • 441
  • 0
Báo cáo y học:

Báo cáo y học: "THR0921, a novel peroxisome proliferator-activated receptor gamma agonist, reduces the severity of collagen-induced arthritis" pps

Báo cáo khoa học

... 5'CCCAAGCAATACCCAAAGAA-3', reverse 5'-CATCAGAGGCAAGGAGGAAA-3'; for monocyte chemoattractant protein-1 (MCP-1), forward 5'-AGCCAGATGCAGTTAACGC-3', reverse 5'-CTGATCTCATTTGGTTCGGA-3'; for RANKL, forward ... proliferator-activated receptor-gamma is a negative regulator of macrophage activation Nature 1998, 391:79-82 30 Sabatini M, Bardiot A, Lesur C, Moulharat N, Thomas M, Richard I, Fradin A: Effects of agonists ... weeks The clinical disease activity of CIA was determined every other day using a three-point scale for each paw Data are expressed as mean ± standard error of the mean (n = 10/group; asterisks...
  • 8
  • 339
  • 0
Báo cáo y học:

Báo cáo y học: " A polymorphism in the interleukin-4 receptor affects the ability of interleukin-4 to regulate Th17 cells: a possible immunoregulatory mechanism for genetic control of the severity of rheumatoid arthritis" doc

Báo cáo khoa học

... differentiation J Immunol 2004, 173:4523-4528 Mitsuyasu H, Yanagihara Y, Mao XQ, Gao PS, Arinobu Y, Ihara K, Takabayashi A, Hara T, Enomoto T, Sasaki S, Kawai M, Hamasaki N, Shirakawa T, Hopkin ... requires validation in a prospective study of early RA patients Approaches that regulate Th17 cells or neutralize their products are under evaluation in the treatment of RA and may be particularly attractive ... H2SO4, was added to each well ELISA plates were read by a Synergy HT plate reader (Biotek, Winsooki, VT, USA) and analyzed by KC4 software (Biotek) Statistical analysis The data were analyzed...
  • 9
  • 472
  • 0
Báo cáo y học:

Báo cáo y học: "Coccidioides posadasii infection alters the expression of pulmonary surfactant proteins (SP)-A and SP-D" pps

Báo cáo khoa học

... (Zymed, San Francisco, CA) served as secondary detection antibody Statistics Statistical analyses of the data (t-test or ANOVA) were done using Prism Software (Graphpad Software, San Diego, CA) The ... hypothesized that the pulmonary surfactant may play an important role in regulating the immune response against C posadasii Among four surfactant proteins, SP -A and SP-D, interact with most of the ... Authors acknowledge the technical assistance of Adrian Donias and Amy Chein in animal studies We also thank Dr Rebecca A Cox (UTHSCSA, San Antonio, TX), Dr Richard J King (UTHSCSA, San Antonio,...
  • 8
  • 229
  • 0
Adoption, use and diffusion of online social networks in the older population : a UK perspective

Adoption, use and diffusion of online social networks in the older population : a UK perspective

Tiến sĩ

... Describes the analysis and findings of a qualitative phase of exploratory research involving Chapter applied research methodology of this research study The reasoning for the selection of of data analysis ... (chapter 2) Chapter also presents the outcomes of a summative evaluation of the research conducted using a comparative analysis of research findings against analysis of findings derived using nationally ... female heads of household for home management and financial management  Computer integration in the form of computer use as part of daily routine In terms of the application of MATH, Zhang & Maruping...
  • 422
  • 267
  • 0
a study on historical and social background and the newness of language use in  pride and prejudice by jane austen = nghiên cứu cơ sở lịch sử, xã hội và tính mới của việc sử dụng ngôn ngữ trong tác phẩm

a study on historical and social background and the newness of language use in pride and prejudice by jane austen = nghiên cứu cơ sở lịch sử, xã hội và tính mới của việc sử dụng ngôn ngữ trong tác phẩm

Khoa học xã hội

... Jane Austen did not portray her as the most beautiful creature in the novel; that was because always in dark eyes, people saw a deep character; always in a strong character, we saw another character ... Components of a Feature of the context SITUATION Field of discourse what was happening, to the nature of the social action that was taking place Tenor of discourse Who were taking part in the situation ... certain arenas: Participants Social processes Collective activities 1.3.1 Participants The participants were the speakers and the speakers‟ attendants – the addressees and certain so-called participants...
  • 61
  • 787
  • 0
A study on historical and social background and the newness of language use in ‘Pride and Prejudice’ by Jane Austen

A study on historical and social background and the newness of language use in ‘Pride and Prejudice’ by Jane Austen

Tổng hợp

... collection and data analysis The study used the descriptive and contextual methods of data collecting and analyzing Basing on the huge resources of library and internet materials, the researcher analyzed ... semiotic -The interpretation of language and meaning London Edward Arnold 19 Halliday, M A K (1989) Context of situation In Michael Halliday and Ruqaiua Hasan, eds., Language, Context and Text: Aspects ... Part One dealt with the general information which contained the rationale, aims and objectives, methodology and scope of the study, Part Two went into further details of the historical and social...
  • 4
  • 364
  • 2
Tài liệu Báo cáo khoa học: Investigation and prediction of the severity of p53 mutants using parameters from structural calculations pptx

Tài liệu Báo cáo khoa học: Investigation and prediction of the severity of p53 mutants using parameters from structural calculations pptx

Báo cáo khoa học

... mutant, R175H) [9] A second advantage of p53 mutation analysis, and a unique feature of this database, is the availability of the residual activity of the majority of p53 missense mutants The ... van der Waals’ radius is rolled over the protein surface ˚ Measure of the percentage of amino acid residues inside a sphere of A that have the same polarity or charge as the wild-type If the amino ... Conservation and complementary parameters (Table 1), the prediction algorithm manages to classify the training data with, on average, 79% accuracy, and to classify the test data with, on average,...
  • 14
  • 561
  • 0
Báo cáo khoa học: Intermonomer cross-linking of F-actin alters the dynamics of its interaction with H-meromyosin in the weak-binding state ppt

Báo cáo khoa học: Intermonomer cross-linking of F-actin alters the dynamics of its interaction with H-meromyosin in the weak-binding state ppt

Báo cáo khoa học

... orientation was practically the same for all actin samples within the limits of experimental error The standard deviations are 0.025 mT H par k and H per k mean that the longer axis (k) of the actin ... to obtain an actin pellet, which was aligned on the surface of a flat cell The hyperfine splitting constant ( 2A zz) was measured parallel and perpendicular to the orientation of the actin filaments ... combined in a molar ratio of : at a total concentration of mgÆmL)1 Such ‘mixed’ G-actin was incubated in the dark with an eightfold molar excess of ABP or ANP in the presence of transglutaminase (0.5...
  • 10
  • 311
  • 0
Báo cáo Y học: The inhibitory region of troponin-I alters the ability of F-actin to interact with different segments of myosin pot

Báo cáo Y học: The inhibitory region of troponin-I alters the ability of F-actin to interact with different segments of myosin pot

Báo cáo khoa học

... AKETLDLRAHLKQVKKEDTEK AKESLDLRAHLKQVKKEDTEK GLCHPRVKVGNEYVTKG APKKDVKKPAAAAAAPAPAPAPAPAPAKPKEEKIDL APKKDVKKPAAAA PKYVKQATLKLAT Ó FEBS 2002 5090 V B Patchell et al (Eur J Biochem 269) a stock ... Sensorgrams were analysed using BIAEVALUA TION software taking account of the small amount of nonspecific binding of the TnI peptide to the control surfaces The association and dissociation rate constants ... that the fractional change in fluorescence was directly proportional to the fraction of the complexes formed The accuracy of the Kd values was gauged from curve fit obtained, the associated R2 value...
  • 13
  • 524
  • 0
TO THE EUROPEAN PARLIAMENT, THE COUNCIL, THE EUROPEAN ECONOMIC AND SOCIAL COMMITTEE AND THE COMMITTEE OF THE REGIONS pdf

TO THE EUROPEAN PARLIAMENT, THE COUNCIL, THE EUROPEAN ECONOMIC AND SOCIAL COMMITTEE AND THE COMMITTEE OF THE REGIONS pdf

Quỹ đầu tư

... full The goal should be to find innovative ways to increase educational attainment and labour market participation Adequate and sustainable social policies and more accessible social services are ... citizens and companies, including in urban areas What is missing today? National approaches and a variety of barriers hold back competitiveness and prevent the exploitation of networks on a European ... in the rail sector and on accelerating the implementation of the Single European Sky should be taken forward as priorities In the field of energy, the latest phase of liberalisation towards the...
  • 11
  • 410
  • 0
COMMUNICATION FROM THE COMMISSION TO THE EUROPEAN PARLIAMENT, THE COUNCIL, ECONOMIC AND SOCIAL COMMITTEE AND THE COMMITTEE OF THE REGIONS ppt

COMMUNICATION FROM THE COMMISSION TO THE EUROPEAN PARLIAMENT, THE COUNCIL, ECONOMIC AND SOCIAL COMMITTEE AND THE COMMITTEE OF THE REGIONS ppt

Tài chính doanh nghiệp

... SMEs’ access to finance and, at the same time, provide important leverage for the capital available for lending As part of its overall proposal on the post-2013 Multiannual Financial Framework, the ... publication of easily accessible and free -of- charge abstracts of European standards with a clear indication of changes made whenever standards are revised The Commission will, and the Member States ... internationalisation and participation in trade fairs (Cyprus, Czech Republic, Denmark, Estonia, France, Ireland, Italy, Latvia, Lithuania, Malta, the Netherlands, Poland, Portugal, the Slovak Republic,...
  • 25
  • 265
  • 0
COMMUNICATION FROM THE COMMISSION TO THE EUROPEAN PARLIAMENT, THE COUNCIL, THE EUROPEAN ECONOMIC AND SOCIAL COMMITTEE AND THE COMMITTEE OF THE REGIONS pptx

COMMUNICATION FROM THE COMMISSION TO THE EUROPEAN PARLIAMENT, THE COUNCIL, THE EUROPEAN ECONOMIC AND SOCIAL COMMITTEE AND THE COMMITTEE OF THE REGIONS pptx

Tài chính doanh nghiệp

... stabilise markets, assure the availability of supplies and ensure that they reach the consumer at reasonable prices, but it will also support the sustainable management of natural resources and ... international humanitarian response The increase in the number of natural and man-made disasters and their economic impact calls for systematic action at European level to strengthen preparedness and ... discussed with the staff representatives as part of the normal social dialogue process and then presented formally to the European Parliament and the Council for adoption as soon as possible DURATION,...
  • 26
  • 382
  • 0
state university of new york press social construction and the logic of money financial predominance and international economic leadership jan 2003

state university of new york press social construction and the logic of money financial predominance and international economic leadership jan 2003

Cao đẳng - Đại học

... that the state will still act to maximize a given rational utility, that of a class rather than that of the population as a whole Thus the discussion of motivation in this branch of the study of ... demands on a country’s balance of payments caused by the maintenance of a relatively open market and a highly valued currency The denomination of a majority of the investment in the international ... demands on a country’s balance of payments caused by the maintenance of a relatively open market and a highly valued currency The denomination of a majority of the investment in the international...
  • 260
  • 1,746
  • 0
báo cáo hóa học:

báo cáo hóa học: " Oral administration of the KATP channel opener diazoxide ameliorates disease progression in a murine model of multiple sclerosis" ppt

Toán học

... phase of EAE, histological spinal cord analysis was performed in animals treated from the appearance of the first clinical signs At the end of treatment, animals were anesthetized, transcardially ... EAE animals Diazoxide treatment diminishes the astrocytic reactivity and area of activated microglia/macrophage in the effector phase of EAE To assess the consequences of diazoxide administration ... the data; and NV, JFEP and MP wrote the manuscript MJR and NM participated in the design of the study and helped draft the manuscript All authors have read and approved the final version of the...
  • 18
  • 422
  • 0
Báo cáo khoa học:

Báo cáo khoa học: "Investigation of some social factors on the evolution of Avian Influenza (AI) and Foot and mouth disease (FMD) in Luong Son district, Hoa Binh province, Vietnam" ppsx

Báo cáo khoa học

... local farm animals due to a wide range of diseases including FMD and AI was high We found that many local farmers have no quarantine areas for new introduced animals (94.20%) This caused a high ... In fact, diseases cannot or rarely occur in the areas where a vaccination strategy is strictly applied A low level of vaccine use plus weakness of local authorities creates ideal chances for the ... 89.57% of holders used traditional modes (raising poultry outdoors on pasture) The high rate of un-managed flocks was also a reason for spreading of disease from area to area Table Purpose of production...
  • 7
  • 349
  • 0
Báo cáo y học:

Báo cáo y học: "The angiogenesis inhibitor protease-activated kringles 1–5 reduces the severity of murine collagen-induced arthritis" ppsx

Báo cáo khoa học

... units/ml Statistical analyses Data were analyzed using the Graph Pad Prism software package (Graph Pad Software, San Diego, CA, USA) Two-way analysis of variance was used to compare effect of different ... and pathological features of established CIA This was accompanied by a significant reduction in the histological features of disease These data indicate that antiangiogenic therapies could have ... collagen-induced arthritis J Immunol 2000, 164:5922-5927 Sone H, Kawakami Y, Sakauchi M, Nakamura Y, Takahashi A, Shimano H, Okuda Y, Segawa T, Suzuki H, Yamada N: Neutralization of vascular endothelial...
  • 8
  • 257
  • 0
Báo cáo y học:

Báo cáo y học: "Ischemic preconditioning reduces the severity of ischemia-reperfusion injury of peripheral nerve in rat" pptx

Báo cáo khoa học

... distinction was made as to endoneurial, perivascular, or subperineurial edema A mean value for each rat was calculated after examination of four sections represented that case Statistics The values ... expressed as mean ± standart of deviation The differences between the groups were analysed by using ANOVA Non-parametric data was evaluated by Mann Whithney-U test A p value less than 0.05 was considered ... examination of Ischemia, I/R and I/R+IP on sciatic nerves of rats at the early period Part which consisted of groups aimed to evaluate the histopathological changes in the nerves days after the...
  • 5
  • 409
  • 0

Xem thêm