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so what are we looking for anyhow

Curcumin for monoclonal gammopathies  what can we hope for, what should we fear

Curcumin for monoclonal gammopathies what can we hope for, what should we fear

Sinh học

... whether curcumin is also safe for patients with monoclonal gammopathies remains, however, to be answered Patients with MGUS are often without symptoms Preventive strategies can therefore not use the ... validated endpoints remains therefore necessary before therapy in the clinic is justified Such data are, so far, lacking It is therefore of the utmost importance to carefully analyze the effects on ... inflammation in other tissues, would benefit most We have so far seen that there are reasons for being hopeful about the potential of curcumin to be beneficial for prevention of monoclonal gammopathies...
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Báo cáo y học:

Báo cáo y học: " Gene therapy in animal models of rheumatoid arthritis: are we ready for the patients" pdf

Báo cáo khoa học

... IL-1Ra or the soluble IL-1 receptor accessory protein [15,16] The ex vivo method also yields a therapeutic effect of IL-1Ra in bacterial cell wall-induced arthritis in rats [17] However, this ex ... such as the herpes simplex virus (HSV), adenoassociated viruses (AAVs) and lentiviruses are thought to integrate into host chromosomes, and therefore potentially could have long-term expression, ... coinjection of two AAV vectors – one for the constitutive expression of rtTA, and the other used the tetO promoter for regulated expression of viral IL-10 – before mice were immunized Doxycycline administration...
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báo cáo khoa học:

báo cáo khoa học: " Implementing telehealth to support medical practice in rural/remote regions: what are the conditions for success?" ppsx

Báo cáo khoa học

... and health regions were also interviewed about the nature of their work and the strategies they were using to attract and keep medical workforce in the region Managers were also asked questions ... respect to continuity of patient care and coordination of clinical activities between various health care organisations and levels of care [7-10] For rural, remote or isolated regions, telehealth is ... and 14 managers were interviewed Perceived telehealth benefits For a majority of physicians and managers, telehealth was perceived as a powerful tool to improve healthcare services for populations...
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Báo cáo y học:

Báo cáo y học: "Are we ready for therapeutic drug monitoring of biologic therapeutics" pot

Báo cáo khoa học

... become widely studied for infliximab and adalimumab, comparable studies for other biologicals are lacking In contrast, reported frequencies of antibodies to etanercept are lower and these antibodies ... lower etanercept concentrations compared to responding patients [abstract] Ann Rheum Dis 2011, 70 (Suppl 3):119 doi:10.1186/ar3395 Cite this article as: Krieckaert CLM, Lems WF: Are we ready for ... concentrations are not widely available (particularly for the new biological therapeutics) and additional research questions need to be resolved, the evidence that these measurements are clinically...
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Báo cáo y học:

Báo cáo y học: "The cuff-leak test: what are we measuring" pps

Báo cáo khoa học

... times and the five values are averaged The two methods were compared in 15 patients and the expiratory leak was consistently lower than the total leak As the ratio between expiratory and total ... study was not to compare the performance of both tests but rather to evaluate the factors influencing the leak As these patients were deeply sedated and even muscle relaxants were used, extubation ... least in part, some of the differences between studies Series in post-operative patients showed that the capacity of the cuff-leak test to predict extubation failure was much lower than in populations...
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Báo cáo y học:

Báo cáo y học: "The Nordic maintenance care program: what are the indications for maintenance care in patients with low back pain" pot

Báo cáo khoa học

... suitable for more frequent past episodes For monthly episodes, 70% were in favour, and 69% for weekly episodes This was in line with the"expected” answers (Table 4) Associations between the demographic ... week Both questions were asked because the data for the present day would be easier collected (just counted) than data for the past week However, the week-data were there in case some respondents ... study, some argued that lack of treatment success could also be an indication for MC [12] We had hoped for some clear indications on this issue, but some confusion remains Perhaps such answers...
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the virtual jirga the 2009 education policy and the medium of instruction debate in pakistan who is participating and what are the implications for balochistan

the virtual jirga the 2009 education policy and the medium of instruction debate in pakistan who is participating and what are the implications for balochistan

Tổng hợp

... this model is well known for conflict resolution in which issues between individuals and communities are solved by consensus In other words this model is a strategic exchange between people to ... as they are in the present day, they were still thought to be the prominent source of propagated information The public media under Muslims was used for creating a mind-set so as to prepare the ... ball), but we never knew what language they were or what they actually meant The school I went to was not fenced There was no toilet, no school uniform and no morning assembly The first thing we did...
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What Are the Implications for Global Value Chains When the Market Shifts from the North to the South?

What Are the Implications for Global Value Chains When the Market Shifts from the North to the South?

Tổng hợp

... scope for profitable Source: US Census Bureau Source: The Median Income before tax in 2007 was £ 17,700 (HM Revenue and Customs) As Wilkinson and Pickett (2009) show, most indicators of welfare are ... investment plans were to carry on, the world price by 2020, for major food crops could rise by 11% for cassava, 26% for maize, 18% for oilseeds, about 12% for sugar and 8% for wheat 21 We believe that ... absolute poverty levels However, in this discussion we are not focusing on the welfare implications of income levels, but on their translation into the demand characteristics of consumption, so...
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INDUSTRY SURVEY - What future animators say about what they are looking for in a school, and what professional animators say are the most important things to look for. ppt

INDUSTRY SURVEY - What future animators say about what they are looking for in a school, and what professional animators say are the most important things to look for. ppt

Cao đẳng - Đại học

... INDUSTRY SURVEY What future animators say about what they are looking for in a school, and what professional animators say are the most important things to look for Quotes throughout are from professional ... VIII RECOMMENDED NEXT STEPS If you are currently looking for an animation school and have clearly defined your personal and professional goals so you know what type of animation training you ... Industry connections 5% Track record for placing students When we asked what was most important in getting a quality animation education, the two areas that tied at 23% were the quality of the curriculum,...
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These Are The Droids You’re Looking For: An Android Guide

These Are The Droids You’re Looking For: An Android Guide

Hệ điều hành

... often posts tutorials for rooting new Android phones Those looking to root should also check the XDA Developer Forums, specifically the Android Software and Hacking General forum Instructions on ... older console games on their Android device are another When Sony released the Sony Xperia Play, many emulators were pulled from the market, presumably because they were competition to Sony’s device ... States.) It promised an open platform for mobile phone software development Some would argue that this promise has not been fulfilled, but Google’s stance on open source undeniably differs from...
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Looking to the Future - What Does Transformation Mean for Military Manpower and Personnel Policy pdf

Looking to the Future - What Does Transformation Mean for Military Manpower and Personnel Policy pdf

Khoa học xã hội

... firm’s performance 8 What Does Transformation Mean for Military Manpower and Personnel Policy? greater variation in the kinds of military careers called for by transformation The lack of personnel ... the relationship between the military transformation now under way and the manpower and personnel policies that are needed to support a transforming force It was prepared for the Conference on ... standards for research quality and objectivity Looking to the Future What Does Transformation Mean for Military Manpower and Personnel Policy? BETH ASCH, JAMES R HOSEK OP-108-OSD June 2004 Prepared for...
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báo cáo sinh học:

báo cáo sinh học:" What if we decided to take care of everyone who needed treatment? Workforce planning in Mozambique using simulation of demand for HIV/AIDS care" pdf

Điện - Điện tử

... who are an important component of the health care team but whose roles are not well defined These individuals are responsible for finding patients who seem to be lost to follow up, and can also ... volumes) A number of essential personnel categories, such as laboratory technicians, are not included at all Available workforce for HIV care is small, ratios are high The number of people with ... the care system secondary to death or loss to follow-up (we assumed 10% per year for those on ART, 50% for those enrolled but not eligible for ART), 3) those with adverse drug reactions (we assumed...
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Báo cáo sinh học:

Báo cáo sinh học: "What are journals for" doc

Báo cáo khoa học

... broken” Stephen Harrison, Harvard, USA “…something surely needs to be done about the review nightmare that so many people face” Arthur Lander, University of California, Irvine, USA “ what is in the ... Moreover there are strong arguments against a blanket insistence on absolutely rigorous validation of data (some Journal of Biology 2009, http://jbiol.com/content/8/1/1 of them are rehearsed for genome-scale ... judgement calls, for referees and for editors, and we shall not always get it right The question is whether iterative reviewing materially affects how often we get it wrong Journals also have a responsibility...
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Báo cáo y học:

Báo cáo y học: "What do we know about communicating risk? A brief review and suggestion for contextualising serious, but rare, risk, and the example of cox-2 selective and non-selective NSAIDs" pot

Báo cáo khoa học

... there were large differences between drugs [6] Similarly, differences between individual coxibs are apparent for gastrointestinal bleeding [7], and between individual coxibs and NSAIDs for myocardial ... number not for citation purposes) Materials and methods We initially searched PubMed using a number of free-text terms for the particular area of interest Thus for literacy, for instance, we sought ... relative risk) We also checked the bibliographies of any relevant studies, risk websites (see [10], for instance) and books, reviews and articles on risk presentation We looked for full journal-published...
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Báo cáo y học:

Báo cáo y học: "The need for prognosticators in rheumatoid arthritis. Biological and clinical markers: where are we now" potx

Báo cáo khoa học

... physical function, however, has been poor for most of them This may be due to a variety of reasons First, what we measure in various body fluids may not reflect sufficiently well what is ongoing in ... including biological agents are usually associated with a fall in CRP levels, and are often also paralleled by reductions in IL-6 serum concentrations [24,69,70] It is somewhat disappointing that ... variables, but also composite indices or functional or radiographic scores (reviewed in [9]) The sources of these clinical markers are the patients’ manifestations as judged by an assessor or by the...
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báo cáo khoa học:

báo cáo khoa học: " So what have data standards ever done for us? The view from metabolomics" potx

Báo cáo khoa học

... material accessible for the next generation of metabolomic software and bioinformatics analysis tools, which again can only be developed and optimized if there are data to work with We also need to start ... technologies However, there are some positive news stories from metabolomics Firstly, although there is still a lack of community repositories for data themselves, there are databases for standard ... and the Madison Metabolomics Consortium Database [14] There are also databases that are already in use, albeit not across the whole community The INTERPRET database [15] has been used for several...
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báo cáo khoa học:

báo cáo khoa học: " TRIPS, the Doha declaration and paragraph 6 decision: what are the remaining steps for protecting access to medicines?" pps

Báo cáo khoa học

... is reviewed every three years by the Economic and Social Council (Ecosoc) according to criteria such as low income, weak human resources and low level of economic diversification [14] However, ... compulsory licensing into law For example, Panama has no national legislative provision for issuing a compulsory license, while Honduras does not include compulsory licensing as a remedy for anti-competitive ... negotiations, individual countries are especially vulnerable to the negotiating power of major trading nations Joint efforts and combined forces are critical to the power imbalances inherent in trade...
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báo cáo khoa học:

báo cáo khoa học: " Introducing oral tobacco for tobacco harm reduction: what are the main obstacles?" potx

Báo cáo khoa học

... to this situation, and will ask some central questions, the answers to which The societal impact of nicotine Whatever the reasons may be, there is no known human society whose members or citizens ... questions are obvious: If smokers are the problem, why aren't they also part of the solution? Shouldn't they be involved in planning tobaccorelated policies? Is it ethical to keep them unaware of ... treatment for long-term heroin users are currently underway in several countries (Switzerland, Netherlands, UK, Canada, USA) It is unfortunate that research that appears to be sound for heroin,...
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Báo cáo khoa học:

Báo cáo khoa học: "The electrocardiogram for sepsis: how close are we" doc

Báo cáo khoa học

... hydrocortisone and fludrocortisone on mortality in patients with septic shock JAMA 2002, 288:862-871 10 Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M, for ... factor, soluble urokinase p-type plasminogen activator receptor, and soluble triggering receptor expressed on myeloid cells-1 in combination to diagnose infections: a prospective study Crit Care ... assessment is unrealistic It is therefore logical that effort is now being directed toward evaluating the utility of biomarker profiles, containing multiple markers, for risk assessment and diagnosis...
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Báo cáo y học:

Báo cáo y học: "A survey of accessibility and utilisation of chiropractic services for wheelchair-users in the United Kingdom: What are the issues" pps

Báo cáo khoa học

... patients sought care for pain control however the source of pain was not identified in this study The main motivations for wheelchair-users seeking care and their key expectations of treatment are ... communication between chiropractors and GPs are vital however, to facilitate optimal care for wheelchair-users Access Issues The first step in achieving equal access to healthcare is to recognise ... study were clinic owners and therefore responsible for the compliance of their clinic with disability law Under part III of the DDA 1995, healthcare providers are required to take all reasonable...
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