skin diseases pertaining to viral infections
Báo cáo sinh học: " Biochemical prevention and treatment of viral infections – A new paradigm in medicine for infectious diseases" doc
Ngày tải lên :
18/06/2014, 22:20
... methods to prevent and inhibit viral infections is to block host cell receptors that are used by viruses to gain cell entry Receptor blockage is commonly achieved via application of MAbs that bind to ... apply this technology to human diseases such as viral infections Some major technical hurdles need to be overcome before siRNA-based anti -viral prophylaxis and treatments move into the clinics Especially, ... pair with specific viral mRNA targets AS-ONs inhibit viral protein production by both blocking viral mRNA translation and triggering its degradation Since the discovery of viral inhibition effect...
- 6
- 568
- 0
báo cáo hóa học:" Biochemical prevention and treatment of viral infections – A new paradigm in medicine for infectious diseases" pdf
Ngày tải lên :
20/06/2014, 04:20
... methods to prevent and inhibit viral infections is to block host cell receptors that are used by viruses to gain cell entry Receptor blockage is commonly achieved via application of MAbs that bind to ... apply this technology to human diseases such as viral infections Some major technical hurdles need to be overcome before siRNA-based anti -viral prophylaxis and treatments move into the clinics Especially, ... pair with specific viral mRNA targets AS-ONs inhibit viral protein production by both blocking viral mRNA translation and triggering its degradation Since the discovery of viral inhibition effect...
- 6
- 561
- 0
Báo cáo khoa học: " Respiratory viral infections detected by multiplex PCR among pediatric patients with lower respiratory tract infections seen at an urban hospital in Delhi from 2005 to 2007" docx
Ngày tải lên :
12/08/2014, 04:22
... presented to the OPD than the ward, similar to a study from Taiwan [26] and could be due to the fact that the patients present earlier after onset of symptoms to the OPD as compared to getting ... pediatric ward positive for different respiratory viruses Site Clinical presentation Total ALRI/total ALRI (%) OPD Pediatric Ward Total virus positive Severe ALRI/total severe ALRI (%) Very Severe ALRI/number ... associated with total viral infections and RSV infection (p < 0.05) Runny nose was significantly present in children with RSV infection (p < 0.05) Among risk factors, ARI in family was found to be associated...
- 11
- 275
- 0
Báo cáo y học: "Bench-to-bedside review: Rare and common viral infections in the intensive care unit – linking pathophysiology to clinical presentatio" ppt
Ngày tải lên :
13/08/2014, 11:22
... Humoral ARDS, acute respiratory distress syndrome; CMV, cytomegalovirus; RSV, respiratory syncytial virus; SARS-CoV, severe acute respiratory syndrome-coronavirus; VHF, viral hemorrhagic fever; ... tract mucus and release viral progeny after cell infection and thus is necessary for subsequent viral entry to viral escape from the host cell [12] Influenza A is divided into subtypes based on ... in SARS pathogenesis [49] In many respiratory infections, MBL prevents receptor attachment, activates complement, and enhances phagocytosis In SARS-CoV infections, low or deficient levels of MBL...
- 9
- 427
- 0
5 awesome nonboring tips to viral success
Ngày tải lên :
07/01/2014, 16:34
... Pastramajlija supporter Owner and author of Stef Social Studio See complet e prof ile Would you like to contribute to this site? Get started » ... they will certainly make your campaign more successful If you have any additional tips, feel free to comment in the section below Connect: Aut hored by: Stefan Jordev E-business management master ... opinion about a certain subject If you have them on your side, you are on the right path You have to connect with some influencers who know the market, and have many connections These days influencers...
- 2
- 239
- 0
Tài liệu Darwiniana Essays and Reviews Pertaining to Darwinism pptx
Ngày tải lên :
18/02/2014, 06:20
... sure to survive, to propagate, and to occupy the limited field, to the exclusion or destruction of the weaker brethren All this we pondered, and could not much object to In fact, we began to contract ... the drift period into that of the present, may be turned to the same account Mammoths, mastodons, and Irish elks, now extinct, must have lived down to human, if not almost to historic times Perhaps ... might occur to any naturalist of an inquiring mind An editorial character for this article must in justice be disclaimed The plural pronoun is employed not to give editorial weight, but to avoid...
- 144
- 309
- 0
Tài liệu Báo cáo khoa học: Type I antifreeze proteins expressed in snailfish skin are identical to their plasma counterparts doc
Ngày tải lên :
20/02/2014, 02:22
... characterization of known skin- type AFPs and the presence of antifreeze activity in skin tissues of other species has led to the hypothesis that skin- type AFPs are widespread ancestors of liver-type ... large type I AFPs and to clarify the relationship between skin and plasma proteins Pursuant to this, an Atlantic snailfish skin cDNA library was screened using a shorthorn sculpin skin- type AFP clone ... nitrogen and stored at )70 °C Skin library construction and screening Total RNA from Atlantic snailfish skin tissue was isolated using TRIzolÒ reagent (Invitrogen Canada Inc, Burlington, ON, Canada)...
- 10
- 400
- 0
Wide Range of Diseases Linked to Pesticides docx
Ngày tải lên :
16/03/2014, 16:20
... to major diseases Inherent limitations, such as the following, only add to the power of these studies as patterns of diseases tied to pesticide exposure emerge: (i) categorizing farmers all together ... women 35 to 50 years old Genetics can only account for five to ten percent of cases According to the Breast Cancer Fund, a growing body of scientific evidence suggests that exposures to toxic chemicals, ... are linked to birth defects, 21 can affect reproduction and 15 are nervous system toxicants A number of published studies using animal toxicity data and human cells/ tissue laboratory data also...
- 9
- 201
- 0
Neuroimmunology of the Skin Basic Science to Clinical Practice ppt
Ngày tải lên :
22/03/2014, 21:20
... Neuroimmunology of the Skin Section II: Stress and Cutaneous Immunity Neuroanatomy of the Skin D Metze Neuroreceptors and Mediators S Ständer and T.A Luger 13 Autonomic Effects on the Skin F Birklein ... µm Localization in epidermis Up to stratum spinosum Up to granular layer Receptors (receptor for growth factors, other receptors) trkA, p75, e.g Histamine receptor, Trp-group c-RET, binding of ... which is due to the loss of vasoconstrictor activity Later on, increased temperature turns into cold skin [47] The reason for this change of symptoms is that vasoconstrictor alphareceptors develop...
- 244
- 416
- 0
Báo cáo khoa học: An orphan dermaseptin from frog skin reversibly assembles to amyloid-like aggregates in a pH-dependent fashion pptx
Ngày tải lên :
23/03/2014, 04:20
... amyloid fibrils are not inherently cytotoxic Nevertheless, the cytotoxicity of certain Ab-amyloid species may depend on structural parameters [34,35] Furthermore, cytotoxicity can be induced by binding ... suspension was added to the cells to a final concentration of 15 lm The concentration of LDH in 200 lL culture supernatants was determined with a Cyto Tox 96Ò non-radioactive cytotoxicity assay (Promega, ... The inherent cytotoxicity of protofibrils is characterized by the intracellular localization of the polypeptides, the intactness of the cell membrane, the onset of apoptosis and mitochondrial damage...
- 11
- 411
- 0
báo cáo hóa học:" Social care and changes in occupational accidents and diseases - the situation in Eastern Europe in general and for skin diseases in particular" pptx
Ngày tải lên :
20/06/2014, 00:20
... skin diseases Slovakia is in third place The rates in Estonia and Latvia are particularly low On average, only two to three skin diseases are registered each year in Estonia as occupational diseases ... Occupational skin diseases The data on occupational skin diseases was particularly defective For this reason, it was not possible to consider any effect of EU membership on the development of skin diseases ... Latvia Although skin diseases are officially recognised occupational diseases in Macedonia, currently none has been registered as such Skin diseases are the most frequent occupational diseases in...
- 15
- 389
- 0
Chapter 055. Immunologically Mediated Skin Diseases (Part 2) ppsx
Ngày tải lên :
07/07/2014, 01:20
... lesional but not uninvolved skin Deposits of IgG on keratinocytes are derived from circulating autoantibodies directed against cellsurface autoantigens Such circulating autoantibodies can be demonstrated ... often progresses to a mucocutaneous disease in which fragile, flaccid blisters rupture to produce extensive denudation of the skin (Fig 55-1) PV typically involves the ... have IgG autoantibodies directed against desmogleins (Dsgs), transmembrane desmosomal glycoproteins that belong to the cadherin family of calcium-dependent adhesion molecules Such autoantibodies...
- 5
- 310
- 0
Chapter 055. Immunologically Mediated Skin Diseases (Part 3) pps
Ngày tải lên :
07/07/2014, 01:20
... In addition to severe skin lesions, many patients with PNP develop life-threatening bronchiolitis obliterans PNP is generally resistant to conventional therapies (i.e., those used to treat PV); ... Although pemphigus has been associated with several autoimmune diseases, its association with thymoma and/or myasthenia gravis is particularly notable To date, >30 cases of thymoma and/or myasthenia ... anti-Dsg1 IgG) and the tissue distribution of this autoantigen (i.e., expression in oral mucosa that is compensated by coexpression of Dsg3) is thought to account for the distribution of lesions in...
- 4
- 295
- 0
Chapter 055. Immunologically Mediated Skin Diseases (Part 4) pdf
Ngày tải lên :
07/07/2014, 01:20
... addition to eosinophils, cell-rich lesions also contain mononuclear cells and neutrophils It is not possible to distinguish BP from other subepidermal blistering diseases by routine histologic ... and bullae on erythematous, urticarial bases (Courtesy of the Yale Resident's Slide Collection.) Biopsies of early lesional skin demonstrate subepidermal blisters and histologic features that ... membrane of normal human skin in indirect immunofluorescence microscopy IgG from an even higher percentage of patients shows reactivity to the epidermal side of M NaCl split skin [an alternative...
- 5
- 259
- 0
Chapter 055. Immunologically Mediated Skin Diseases (Part 5) docx
Ngày tải lên :
07/07/2014, 01:20
... antigastric parietal cell autoantibodies These associations likely relate to the high frequency of the HLAB8/DRw3 haplotype in these patients, since this marker is commonly linked to autoimmune disorders ... develop in patients later exposed to oral contraceptives Occasionally, infants of affected mothers demonstrate transient skin lesions Biopsies of early lesional skin show teardrop-shaped subepidermal ... produced by low titer IgG anti-basement membrane autoantibodies directed against BPAG2, the same hemidesmosome-associated protein that is targeted by autoantibodies in patients with BP—a subepidermal...
- 5
- 241
- 0
Chapter 055. Immunologically Mediated Skin Diseases (Part 6) pdf
Ngày tải lên :
07/07/2014, 01:20
... autoantibodies directed against type VII collagen—the collagen species that comprises anchoring fibrils Such IgG autoantibodies bind the dermal side of M NaCl split skin (in contrast to IgG autoantibodies ... histologically, and immunopathologically resemble those seen in patients with inflammatory EBA Treatment of EBA is generally unsatisfactory Some patients with inflammatory EBA may respond to ... neutrophil-rich inflammatory lesions) may respond to dapsone The chronic, noninflammatory form of this disease is largely resistant to treatment, although some patients may respond to cyclosporine,...
- 6
- 283
- 0
Chapter 055. Immunologically Mediated Skin Diseases (Part 7) docx
Ngày tải lên :
07/07/2014, 01:20
... papules, heliotrope erythema, and poikiloderma serve to distinguish patients with dermatomyositis Skin biopsy of erythematous, scaling lesions of dermatomyositis may reveal only mild nonspecific inflammation ... distinguishes dermatomyositis from these two diseases Cutaneous changes may be similar in scleroderma and dermatomyositis and may include thickening and binding down of the skin of the hands (sclerodactyly) ... disease Topical glucocorticoids are sometimes useful; patients should avoid exposure to ultraviolet irradiation and use photoprotective measures such as broad-spectrum sunscreens Figure 55-3 Dermatomyositis...
- 5
- 260
- 0
Chapter 055. Immunologically Mediated Skin Diseases (Part 8) docx
Ngày tải lên :
07/07/2014, 01:20
... scaling papules tend to merge into large plaques, some with a reticulate appearance The annular form involves the same areas and presents with erythematous papules that evolve into oval, circular, ... erythematous and slightly edematous papules and plaques (B, Courtesy of Robert Swerlick, MD.) Subacute cutaneous lupus erythematosus (SCLE) is characterized by a widespread photosensitive, nonscarring ... microscopy of lesional skin frequently reveals deposits of immunoglobulin(s) and complement in the epidermal basement membrane zone Treatment is aimed at control of systemic disease; photoprotection in...
- 5
- 307
- 0
Chapter 055. Immunologically Mediated Skin Diseases (Part 9) doc
Ngày tải lên :
07/07/2014, 01:20
... erythematosus) Scleroderma and Morphea The skin changes of scleroderma (Chap 316) usually begin on the hands, feet, and face, with episodes of recurrent nonpitting edema Sclerosis of the skin begins ... lupus erythematosus Violaceous, hyperpigmented, atrophic plaques, often with evidence of follicular plugging, which may result in scarring, are characteristic of discoid lupus erythematosus (also ... taut skin over the nose, shrinkage of tissue around the mouth, and perioral radial furrowing (Fig 55-8) Matlike telangiectases are often present, particularly on the face and hands Involved skin...
- 5
- 243
- 0
Chapter 055. Immunologically Mediated Skin Diseases (Part 10) pot
Ngày tải lên :
07/07/2014, 01:20
... subepidermal blistering diseases: Advances in the clinic and the laboratory Adv Dermatol 16:113, 2000 [PMID: 11094626] Sontheimer RD: Skin manifestations of systemic autoimmune connective tissue ... appear to be at increased risk to develop bone marrow failure or other hematologic abnormalities While the ultimate course of eosinophilic fasciitis is uncertain, many patients respond favorably to ... arthralgias, pulmonary symptoms, and peripheral edema In a later phase (i.e., 3–6 months after initial symptoms), these patients often develop localized sclerodermatous skin changes, weight loss,...
- 5
- 270
- 0