... Audit Institutions ofthe Member States ofthe European Union andthe European Court of Auditors, during the Meeting on 6-7 December 2004 in Luxembourg, took note ofand discussed the “Guidelines ... audited (including a summary of the results of previous audits and their impacts); 3. Reasons for the audit; 4. Factors affecting the audit, including those determining the materiality of matters ... work summing up general findings and recommendations. The report may entail the analysis ofthe SAI work inthe previous year, including information on audit work, information on training activity;...
... By coming into close contact, and becoming better acquainted with each other, they find that they hold to the same doctrinal standards, and theyexplain them inthe same manner; they have the same ... become an integral part ofthe Church in England. They are now an integer of themselves. To make one portion of them an integral part ofthe Church in this country, and another portion an integral ... repealed, and remains therefore infull force and virtue. Nor, if the reasoning in this report be correct,would they have the law repealed, believing as they do, that the maintenance ofthe principle...
... hydrolysis ofthe nucleotide. To investi-gate thein uence ofthe binding and ⁄ or hydrolysis of ATP on the interaction ofthe AAA-peroxins, Pex1p and Pex6p carrying mutated ATP-binding sites ... do interact in vivo. We assigned their corresponding binding sites and elucidated the importance of ATP-binding and -hydrolysis of Pex1p and Pex6p for theirinteraction. We show that the interaction ... interaction. This in turn is in line with the previous observation that adistinct point mutation inthe vicinity ofthe WalkerAmotif in Pex1pD2 attenuates the interaction of bothAAA-peroxins...
... indicating that interaction with Smac is notrequired with respect to the role of HSP70 inthe inhi-bition ofthe release of Smac and apoptosis. The role ofthe ATP-binding domain of HSP70 in ... ATP-binding domain of HSP70,rather than the peptide-binding domain, was essential for these observedHSP functions. Taken together, our results provide evidence supporting the role of HSP70 inthe ... transfectedC2C12 cells. Furthermore, there was no direct interac-tion between HSP70 and Smac proteins, and the ATP-binding domain of HSP70, rather than the pep-tide-binding domain, was essential for...
... more insight into the role ofthe fat breast tis-sue, we investigated the independent effects ofthe size of dense tissue andthe size of non-dense tissue inthe breast and their combined effects ... out. The non-dense area was obtained by subtracting the densearea from the total breast size. The size ofthe dense and non-dense areas in cm2, was determined by multiplying the number of pixels ... dense than for the non-densearea. Therefore, the resulting risk depends on the composi-tion ofthe breast and not simply on the size ofthe breast.When studying dense breast tissue in relation...
... footprint. Letters to the right of eachpanel indicate the DNA sequence (5Â end inthe upper part) ofthe corresponding strand in this region. Inthe lower part, the sequence of the binding site ... position ofthe footprint. Letters to the right of each panel indicate the DNA sequence (5Â end inthe upper part) of the corresponding strand in this region. Below the footprints, the sequence ofthe ... HAKN1 N-terminal arm. In addition to a role ofthe N-terminal arm in contact-ing the first two amino acids ofthe core, examinationFig. 6. Effect of changes within the N-terminal arm and position...
... ligand are cross-linked to domainsI and III, respectively, ofthe receptor [19,22]. The b sheet of EGF may bind to domain I of ErbB-1, andthe other surface of the ligand binds to domain III of ... group is composed of the ligands that bind to both ErbB-1 and ErbB-4, such asbetacellulin, heparin-binding EGF, and epiregulin. The binding of ligands to the extracellular region of receptors causes ... to the EGF receptor. A deletion in the N-terminal region of domain I impaired the EGF binding of ErbB-1 [21]. The N-terminus of EGF was linked to Tyr101 in domain I by using a covalent cross-linking...
... scared by the interminable singing, shouting, bell-jingling, horn-blowing, and other such merry noises ofthe moving caravan, could be seen disappearing inthe distance. Leaving the park, ... of their parents inthe same way as inthe first instance the parents took care of them. Twins are usually hailed with delight, because they swell the power ofthe family, though in some instances ... grinding corn, making pottery and baskets, and taking care ofthe house andthe children, besides helping the slaves whilst cultivating, or even tending the cattle sometimes. Now, descending...
... got the best of two bloomin' Yankees, an' the other is sneakin' in some corner!"There came the sound of hurried footsteps, and then the light ofthe lantern so far illumined ... to feed the prisoners, including the curs inthe hold, and Jerry, Jim and I ate on the deck aft, where I could at the same time keep the pungy inthe channel.Jim brought out some ofthe stores ... uponit, andthe only wonder was that the Britishers did not awaken sooner. The noise we made in ascending the stairs seemed to me loud enough to alarm the inmates ofthe house nearat hand, and, therefore,...
... knives, and hatchets cutting and slashing,thumping and bawling, fighting and tearing, tumbling and wrestling up to their knees in filth and blood in the middle ofthe carcass. When a tempting morsel ... crossing the road to the northward, drains these lands to the Malagarazi river, and thence into the Tanganyika lake. Thence, having spent the night inthe jungle, we next morning pushed into the ... But inthe centre ofthe continent, within 5Đ ofthe equator, we find the rains much more lasting. For instance, at 5Đ south latitude, for the whole six months that the sun is in the south, rain...
... century andthe creation ofthe Eisenhower Interstate System inthe 1950s and 1960s. Observers have concluded that in both of these cases there was a causal link running from infrastructure investments ... in this plant. 40 This is another example ofthe geographic diversity of benefits which comes from investing in infrastructure. The Costs of Underinvesting in Infrastructure Although infrastructure ... time and money, so that they can retain more of their income for other purposes and spend more time doing what they want, rather than spending time getting there. One study concluded that individuals...
... percent chance of remaining at the top ofthe distribution. This indicates that education among those born inthe top quintile plays a strong role in maintaining higher levels of income across ... to the schools. This would expand the number of schools that can participate inthe Perkins program since they would no longer bear the overhead cost of administering Perkins loans and there ... narrowed since.22Figure 5: Relative Wages and Quantity of Skilled Workers The increasing relative earnings of college graduates is a combination of increasing earnings for college graduates and...
... Accounting Office, the smoking rate among teenage girls quintupled in a single year following the opening ofthe market to the multinational tobacco companies. The evidence on the impact of price ... an IPM training approach in which farmers learn to observe the development of their crops andthe numbers of pests and beneficial insects in their fields. Based on their analysis ofthe agricultural ... building -in sufficient funding for extensive and comprehensive tracking of M&E indicators throughout the beginning, middle and end of loan cycles. Such full funding would indicate the political...
... the classroom, andthe intrinsic, relating to activities inthe classroom. In their study of extrinsic motivation, Wenden and Rubin (1987) distinguished between integrative and instrumental ... use ofin learning and using a language (Richards, 2000: 445).Second language reading is a process of how the mind functions during reading rather than the product of reading. The focus on individual ... conception ofthe use of reading strategies in their learning reading comprehension and implication for classroom learning and teaching. v reading strategies use for improving their academic reading...
... professors in other disciplines since all devoted their energies to advanced teaching and research. In Flexner’s words, The professor of medicine is primarilya student of problems and a trainer ... school leader ofthe period, the greatestsingle deficiency of medical education inthe early 1900s was the conduct of work inthe clinical departments.43 The model of clinical instruction to ... education), the institutions of medical training, and the complex interactions between academic health centers and the society they were created to serve. The story includes such issues as the financing...