short life is associated with increased sensitivity to stress
Báo cáo y học: " Endothelial Endotoxemia related to cardiopulmonary bypass is associated with increased risk of infection after cardiac surgery: a prospective observational stud" pptx
Ngày tải lên :
14/08/2014, 07:21
... Thus, this period of endotoxemia represents the first “hit” in a two “hit” model of risk Faist et al first used this “two hit” hypothesis to describe the increased risk of development of sepsis in ... largely been disappointing Strategies have included antagonists to the endotoxin Toll-like receptor (TLR4), extracorporeal endotoxin removal systems, performance “off pump” cardiac surgery to eliminate ... levels Importantly, endotoxemia at the conclusion of CPB is associated with a significant risk of the development of postoperative infections Further research is necessary to assess whether a targeted...
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báo cáo hóa học: " Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission?" doc
Ngày tải lên :
19/06/2014, 22:20
... depression [13] This hypothesis is based on the observation that the above mentioned proinflammatory cytokines induce a shift from serotonin synthesis to tryptophan Page of metabolism via the kynurenine ... application for double immunohistochemistry J Histochem Cytochem 1982, 30:1079-1082 37 Polak M, Haymaker W, Johnson JE, D’Amelio F: Neuroglia and their reactions In Histology and Histopathology of the Nervous ... imbalances are associated with acute disease phases In a postmortem study of chronically stable patients with MDD or BD, transient microglial changes may be missed account for the histo-architectural...
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Báo cáo y học: "Emphysema is associated with increased inflammation in lungs of atherosclerosis-prone mice by cigarette smoke: implications in comorbidities of COPD" ppsx
Ngày tải lên :
11/08/2014, 03:20
... measured by ELISA using respective duo-antibody kits (R&D Systems, Minneapolis, MN) according to the manufacturer’s instructions Immunohistochemical staining for tissue macrophages Immunohistochemical ... susceptible to increased lung inflammatory cell influx in response to CS Augmented inflammatory response in the lung from environmental stress or toxicants results in the activation of inflammatory ... exposure augments the proinflammatory cytokine levels in lungs of ApoE-/- mice In order to confirm whether the inflammatory cell influx was associated with proinflammatory cytokine release in ApoE-/-...
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Báo cáo y học: "Emphysema is associated with increased inflammation in lungs of atherosclerosis-prone mice by cigarette smoke: implications in comorbidities of COPD" potx
Ngày tải lên :
11/08/2014, 06:22
... measured by ELISA using respective duo-antibody kits (R&D Systems, Minneapolis, MN) according to the manufacturer’s instructions Immunohistochemical staining for tissue macrophages Immunohistochemical ... susceptible to increased lung inflammatory cell influx in response to CS Augmented inflammatory response in the lung from environmental stress or toxicants results in the activation of inflammatory ... exposure augments the proinflammatory cytokine levels in lungs of ApoE-/- mice In order to confirm whether the inflammatory cell influx was associated with proinflammatory cytokine release in ApoE-/-...
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báo cáo khoa học: " Timing is everything: early degradation of abscission layer is associated with increased seed shattering in U.S. weedy rice" doc
Ngày tải lên :
11/08/2014, 11:21
... rice has a distinct mechanistic basis from that of the shattering wild ancestor of rice, consistent with the reevolution of this trait in weedy groups from domesticated ancestors Surprisingly, independently ... by Toluidine Blue O Protoplasma 1964, 59:367-373 doi:10.1186/1471-2229-11-14 Cite this article as: Thurber et al.: Timing is everything: early degradation of abscission layer is associated with ... easily with the floral tissue at flowering The lack of an abscission layer at flowering in all three indica cultivated accessions is consistent with their lack of shattering (average BTS = 70 to...
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Báo cáo y học: "Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment" potx
Ngày tải lên :
12/08/2014, 11:22
... NM_000577 Interleukin receptor antagonist IRF2 NM_002199 Interferon regulatory factor IRF7 NM_001572 Interferon regulatory factor X X X X X X X X X X ISG15 NM_005101 ISG15 ubiquitin-like modifier ... response to infliximab treatment is associated with treatmentinduced increase in type I IFN response gene activity Discussion In this study, we demonstrated that blockade of the inflammatory cytokine ... Association of interferon regulatory factor haplotypes, similar to that found in systemic lupus erythematosus, in a large subgroup of patients with rheumatoid arthritis Arthritis Rheum 2008, 58:1264-1274...
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Báo cáo y học: "(Sub)clinical cardiovascular disease is associated with increased bone loss and fracture risk; a systematic review of the association between cardiovascular disease and osteoporosis" ppsx
Ngày tải lên :
12/08/2014, 15:22
... expression is increased in response to inflammatory markers, LDL and oxidative stress and this increased expression was associated with increased mineralisation [100-102] den Uyl et al Arthritis Research ... atherosclerosis and osteoporosis An increased IMT has been associated with severity of atherosclerosis and increased cardiovascular risk and considered useful in identifying subjects with increased risk ... osteoporosis and specific categories of CV disease Links between CV disease and osteoporosis Common pathogenesis CV disease is preceded by atherosclerosis, for example, arterial disease Atherosclerosis...
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Báo cáo khoa học: "Occult hypoperfusion is associated with increased mortality in hemodynamically stable, high-risk, surgical patients" pdf
Ngày tải lên :
12/08/2014, 20:20
... same group of investigators in trauma patients have shown that persistent occult hypoperfusion is associated with increased morbi-mortality, and early correction seems to improve outcome [7,8,16] ... study to examine whether serial blood lactate levels could be used as predictors of outcome in this population Nonsurvivors (n = 7) Clinical diagnosis Chronic obstructive pulmonary disease 12 Ischemic ... (e.g pancreatitis, peritonitis); and previous disease of a vital organ, defined as compensated or prior congestive cardiac failure, previous clinical indication of ischemic heart disease (previous...
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Báo cáo y học: "The risk for bloodstream infections is associated with increased parenteral caloric intake in patients receiving parenteral nutrition" pdf
Ngày tải lên :
13/08/2014, 08:20
... attributed to TPN -associated hyperglycemia [10,17] This risk is not restricted to surgical patients Patients receiving stem cell transplantation have an increased infection risk with TPN -associated ... admission diagnosis was not associated with an increased risk for BSI Diagnosis of BSI was a median of 7.5 days (3–14 days) after initiation of TPN As expected, ICU admission was an important risk ... higher risk for BSI in association with increased average parenteral calories Taken together, this information suggests that increased parenteral calories, however quantified, are related to increased...
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Báo cáo y học: "Duration of red blood cell storage is associated with increased incidence of deep vein thrombosis and in hospital mortality in patients with traumatic injuries" potx
Ngày tải lên :
13/08/2014, 19:20
... of storage in this study population References • Mortality at 30 days was increased with to units of RBCs of 28 or more days of storage in this study population • This is the first study to specifically ... and increased risk of sepsis independently associated with old RBCs will also increase these risks [25,27,35-38] We theorize that the hyper-inflammatory and hypercoagulable state associated with ... indicates that patients with type A blood have increased concentrations of factor VIII and von Willebrand's factor, which was associated with increased risk of DVT [40] In our analysis, although there...
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Báo cáo y học: "High serum cortisol level is associated with increased risk of delirium after coronary artery bypass graft surgery: a prospective cohort study" pps
Ngày tải lên :
14/08/2014, 07:21
... serum cortisol level was associated with significantly increased risk of postoperative delirium in this risk-adjusted analysis (odds ratio [OR] 3.091, 95% confidence interval [CI] 1.763 to 5.418; ... graft surgery • High serum cortisol level was associated with increased risk of postoperative delirium Whether this relationship is causal or due to other confounders is still unclear • Patients ... elevated serum cortisol level on the first day after surgery was highly correlated with increased risk of postoperative delirium Other independent risk factors included increasing age, history of diabetes...
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Báo cáo y học: " High sensitivity C-reactive protein is associated with lower tibial cartilage volume but not lower patella cartilage volume in healthy women at mid-life" pdf
Ngày tải lên :
09/08/2014, 10:23
... high -sensitivity C-reactive protein levels are associated with local inflammatory findings in patients with osteoarthritis Osteoarthritis Cartilage 2007, 15:516-523 Matsumoto T, Tsurumoto T, ... significance), thus explaining up to 6% of the variance of cartilage volume Statistical analysis The analytical approach used in this analysis was linear regression with total tibial and patella cartilage ... assessed by high sensitivity C reactive protein Ann Rheum Dis 2004, 63:200-205 Punzi L, Oliviero F, Ramonda R, Sfriso P, Todesco S: Laboratory findings in osteoarthritis Semin Arthritis Rheum 2005,...
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Báo cáo y học: " Enhanced macrophage tropism of HIV in brain and lymphoid tissues is associated with sensitivity to the broadly neutralizing CD4 binding site antibody b12" ppsx
Ngày tải lên :
12/08/2014, 23:21
... entry into macrophages is associated with sensitivity to neutralizing mAb b12 and a broadly neutralizing HIVEnhanced Enhanced HIV entry into macrophages is associated with sensitivity to neutralizing ... neutralization sensitivity to mAb b12 and neutralization sensitivity to sCD4 (p = 0.3279; Additional file 1) These results suggest that macrophage tropism is associated with increased sensitivity to mAb ... late-stage AIDS patients have enhanced macrophage tropism together with increased neutralization sensitivity to b12 compared to viruses isolated from asymptomatic HIV-infected individuals [30] Anti-CD4...
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Báo cáo y học: " Off hour admission to an intensivist-led ICU is not associated with increased mortality" pps
Ngày tải lên :
13/08/2014, 16:21
... the organisational model with intensivists present during the day and residents supervised by intensivist during off hours is adequate enough to avoid a 'quality gap' during off hours This study ... (0.63 to 0.84) 0.80 (0.64 to 0.99) SMR SAPS II 0.78 (0.67 to 0.90) 0.80 (0.64 to 1.00) SMR APACHE II 0.66 (0.56 to 0.79) 0.71 (0.58 to 0.85) SMR SAPS II 0.69 (0.58 to 0.82) 0.70 (0.58 to 0.85) ... Admission type 14.8 0.001 Admission type (1) 0.001 0.969 0.995 (0.772 to 1.283) Admission type (2) 9.15 0.002 1.377 (1.119 to 1.695) Off hours admission 1.89 0.121 1.125 (0.969 to 1.306) Admission...
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Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc
Ngày tải lên :
16/02/2014, 15:20
... SF2 is a genuine SG component (Fig 4B) To determine whether other cellular stresses led to the migration of ASF ⁄ SF2 into SGs, COS cells expressing HA-ASF ⁄ SF2 were exposed to cytoplasmic stresses ... pathway is a pre-requisite for ASF ⁄ SF2 migration into SGs upon stress Because both RRMs contributed to ASF ⁄ SF2 cytoplasmic redistribution, we investigated their intrinsic capacity to so by ... determinants and mechanisms of the subcellular distribution of TIAR [5], as well as its capacity to assemble into cytoplasmic stress granules (SGs) [12,13] However, the molecular mechanism by which TIAR...
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Tài liệu Báo cáo khoa học: Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines docx
Ngày tải lên :
19/02/2014, 05:20
... expression with each of two different siRNAs is consistently associated with increased expression of HO-1 mRNA and protein Moreover, we provide evidence 5340 that at least three mechanisms may ... heme synthesis and degradation to cellular heme content, we treated YN-1 erythroleukemia, HeLa cervical cancer, and HepG2 hepatoma cells for 48 h with succinylacetone (SA) or Sn-protoporphyrin ... of HO-1 mRNA In this context, we have reported that maximum induction of HO-1 mRNA expression was detected within h by treatment with cadmium in HeLa cells, which is due to increased transcription...
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Báo cáo khoa học: Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C pdf
Ngày tải lên :
08/03/2014, 08:20
... reported to undergo ligand-mediated internalization with a t1/2 of in HEK293 cells [3] Forty to fifty per cent of the internalized receptor is recycled back to the surface and the rest is directed to ... activity This requirement for prolonged treatment of cells to ST to observe desensitization, is in contrast to the rapid inactivation that is seen for other members of the guanylyl cyclase receptors, ... GC-C signaling pathway is modulated in vivo in response to ligand In T84 cells, 18 h ST treatment led to cellular refractoriness to further ST stimulation and this refractoriness was contributed...
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Báo cáo khoa học: A distinct sequence in the adenine nucleotide translocase from Artemia franciscana embryos is associated with insensitivity to bongkrekate and atypical effects of adenine nucleotides on Ca2+ uptake and sequestration pdf
Ngày tải lên :
29/03/2014, 00:20
... that the ANT of our mitochondrial preparations of A franciscana embryos is fully functional ANT of A franciscana is refractory to inhibition by BKA As mentioned above, BKA was without an effect on ... failed to inhibit ANT operation as compared with the control (5 mm NH4OH, which is the vehicle of BKA, trace c) With the same BKA stocks, this poison fully inhibited ANT operation in rat liver mitochondria ... from broken mitochondria in the suspension The effect of oligomycin alone is hard to predict, because this inhibitor blocks both ATP formation by polarized mitochondria and ATP hydrolysis by depolarized...
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Báo cáo hóa học: " Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer" ppt
Ngày tải lên :
18/06/2014, 16:20
... assisted with the data collection and helped draft the manuscript IBJ assisted with the statistical analysis JM assisted with data collection and helped to draft the manuscript JB assisted with ... arrest and apoptosis [2,5,6] Several mechanisms have been implicated in cisplatin resistance, i.e decreased drug uptake, insufficient DNA-binding of the drug, increased DNA-repair of cisplatin adducts ... supplemented with glutamine, 10% fetal bovine serum and 1% pencillin/streptomycin in a humidified incubator of 5% CO2 at 37°C Cisplatin (Sigma-Aldrich, St Louis, MO, USA) was dissolved in 0.9% NaCl to...
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báo cáo hóa học:" Increased androgen receptor expression in serous carcinoma of the ovary is associated with an improved survival" doc
Ngày tải lên :
20/06/2014, 07:20
... regard to cardiovascular risk factors and enrolled 10.902 women[12] The standard surgical management was a total abdominal hysterectomy, bilateral salpingo-oophorectomy and omentectomy with cytological ... should incorporate this in any multivariate analysis While associated with AR expression, neither ER nor PR expression correlated with survival in this study Such findings contrast with Lee et al who ... as a single disease, but rather several distinct entities with different clinical behaviours These entities are in part reflected in histopathological characteristics and therefore, to obtain better...
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