... determinants of spread of causal agent ofsevereacute respiratory syndrome in Hong Kong Lancet, 2003 361:1761-6 68 Pan S.F., et al Cardiac arrest in severeacute respiratory syndrome: analysis of 15 ... serum of patients with severeacute respiratory syndrome Clin Chem, 2003 49:197680 63 Paul N.S., et al Prognostic Significance of the Radiographic Pattern of Disease in Patients with SevereAcute ... Effectiveness of non-invasive positive pressure ventilation in the treatment ofacute respiratory failure in severeacute respiratory syndrome Chest (in press) 44 Liu X.Q., et al Management of critical severe...
... situations with a high prevalence ofsevereacute malnutrition, preventing hundreds of thousands of child deaths when applied at scale Uncomplicated forms ofsevereacute malnutrition should be treated ... treated for severeacute malnutrition will need 10–15 kg of RUTF, given over a period of six to eight weeks Community-based management ofsevereacute malnutrition in the context of high HIV ... children with medical complications and implemented on a large scale, community-based management ofsevereacute malnutrition could prevent the deaths of hundreds of thousands of children Nearly...
... six copies of the N protein, respectively (C) The RNA binding efficiency of N protein is represented as a percentage of bound RNA (i.e the percentage of bound RNA = 100%)percentage of free probe) ... localization of SRPK1 Coexpression of SRPK1 could modulate cellular localization of the N protein, suggesting that the N protein is a substrate of SRPK1 in cells (Fig 6) Phosphorylation of the transmissible ... of early replication and budding of SARS-coronavirus Virology 361, 304–315 50 Rowland RR, Chauhan V, Fang Y, Pekosz A, Kerrigan M & Burton MD (2005) Intracellular localization of the severe acute...
... cell culture system of SARS-CoV, bananin inhibited viral replication at a half maximal effective concentration of less than 10 lm and a concentration causing 50% of cell death of over 300 lm, suggesting ... Chang Q, Xie JP, Liu XQ et al (2003) Epidemiology and cause ofsevereacute respiratory syndrome (SARS) in Guangdong, People’s Republic of China, in February Lancet 362, 1353–1358 24 Kao RY, Tsui ... Watt RM, Huang JD, Hu L, Chen G, Chen Z, Zhang L et al (2004) Identification of novel small-molecule inhibitors ofsevereacute respiratory syndrome-associated coronavirus by chemical genetics Chem...
... which 3a contributes to the reduction of cell surface expression of S Given that a full-length infectious clone of SARS-CoV has been assembled [23], the use of reverse genetics would certainly ... expression of S on the cell surface and enhance cellcell fusion, a process that is important for viral spreading Table shows a comparison of the amino acid sequences of the cytoplasmic tails of the ... 84:2305-2315 Ziebuhr J: Molecular biology ofsevereacute respiratory syndrome coronavirus Curr Opin Microbiol 2004, 7:412-419 Tan Y-J, Lim SG, Hong W: Characterization of viral proteins encoded by the...
... which 3a contributes to the reduction of cell surface expression of S Given that a full-length infectious clone of SARS-CoV has been assembled [23], the use of reverse genetics would certainly ... expression of S on the cell surface and enhance cellcell fusion, a process that is important for viral spreading Table shows a comparison of the amino acid sequences of the cytoplasmic tails of the ... 84:2305-2315 Ziebuhr J: Molecular biology ofsevereacute respiratory syndrome coronavirus Curr Opin Microbiol 2004, 7:412-419 Tan Y-J, Lim SG, Hong W: Characterization of viral proteins encoded by the...
... complication probability; SARP = severeacute radiation pneumonitis; * Comparison of dosimetric factors between patients who developed severeacute RP and those who did not severe radiation pneumonitis ... volume of normal lung receiving 10 Gy or more is large with IMRT Table 4: Observed rates of SARP as a function of dosimetric parameters (NTCP/V10) Varibale Median(Range) Group No of patients No of ... file Clinical parameters predictive of risk of RP as reported in the literature The file contains a number of important clinical parameters predictive of risk of RP as reported in the literature...
... identification of a new coronavirus as the causative agent of SARS and of a southern Chinese province as the first area of occurrence, animal species of this area have been speculated to be the origin of ... covalent attachment of the methyl ketone group at P1 of the inhibitor to the catalytic cysteine of the enzyme In spite of 40% and 44% sequence identity, respectively, to the Mpros of HCoV 229E and ... investigate the cause ofsevereacute respiratory syndrome Lancet 2003, 361:1730-1733 Oxford JS, Bossuyt S, Lambkin R: A new infectious disease challenge: Urbani severeacute respiratory syndrome...
... al.: Identification ofsevereacute respiratory syndrome in Canada N Engl J Med 2003, 348:1995-2005 Centers for Disease Control and Prevention (CDC): Outbreak ofsevereacute respiratory syndrome ... concerned with the possibility of human error in this scenario, especially because of the reported transmission of SARS to protected HCWs involved in the intubation of a SARS patient [3] We had ... area, supplies and assistants Because of the urgent nature of the crisis and time restraints we were unable to make a full evaluation of the effectiveness of our training We evaluated only satisfaction...
... measurement of intraabdominal compartment pressure An observational study of 293 patients with severeacute pancreatitis [14] demonstrated that early onset of organ dysfunction (within 72 hours of onset ... presence of gas can indicate infection It should also be remembered that a clinical diagnosis of infected necrosis based on fever, leucocytosis and other markers of sepsis without substantive proof of ... necrosis: assessment of outcome related to quality of life and cost of management Br J Surg 1993, 80:1579-1582 McKay CJ, Imrie CW: The continuing challenge of early mortality in acute pancreatitis...
... levels were subnormal in 92% of patients with MOF and in 44% of controls Low PC was found to precede MOF, and early APC/PC ratios were frequently high in MOF Page of (page number not for citation ... for improvement of PC homeostasis during the course of MOF It thus seems that, in patients developing MOF, the PC activation system reached its limits prior to the diagnosis of MOF, resulting in ... the median level of APC was 105% (85–188), that of PC was 74% (8–165), and that of the APC/PC ratio was 1.45 (1.13–13.2) In the 10 survivors of the case group, the median level of APC was 98% (76–...
... The prevention of psychiatric complications through the development of active coping strategies has recently become a focus of research interest [7,8] Study profile profile The aim of this study ... analysis and showed that a score of 35 points or more was a cutoff with a sensitivity of 77% and a specificity of 97.5% for the diagnosis of PTSD [13] The ability of PTSS-10 in comparison to structured ... outcome of survivors in a specialized centre for the treatment of ARDS The high rate of 'nightmares' in our study compared with the study of Granja and colleagues might be a result of the duration of...
... constraints are critical for the expansion of CTC, we are aware of only one published study reporting original data on costs of ambulatory treatment ofsevereacute malnutrition in a developing country ... free of charge The aims of this study were 1) to describe the outcomes of CTC in Lusaka, 2) to estimate the costs of CTC and 3) to estimate the effectiveness and cost effectiveness of this type of ... Sadler K, Hallam A: Management ofsevereacute malnutrition in children Lancet 2006, 368:1992-2000 Ashworth A: Efficacy and effectiveness of community-based treatment ofsevere malnutrition Food Nutr...
... 141 of structure of STI/A mutant with those of native protease determined in different pH 18 Chapter - SevereAcute Respiratory Syndrome 1.1 SevereAcute Respiratory Syndrome (SARS) SevereAcute ... principle of enzyme evolution, where the catalytic machinery achieves improved regulation through oligomerization TABLE OF CONTENTS Chapter - SevereAcute Respiratory Syndrome 1.1 SevereAcute Respiratory ... Family Index Index Acknowledgements Summary Table of Contents List of Abbreviations 12 List of Figures 14 List of Tables 17 References 155 List of Publications 163 Appendices 164 Acknowledgements...
... Effectiveness of Convalescent Plasma and Hyperimmune Immunoglobulin for the Treatment ofSevereAcute Respiratory Infections of Viral Etiology: A Systematic Review and Exploratory Meta-Analysis Journal of ... Failure and Guidelines for the Use of Innovative Therapies in Sepsis Chest 2002; 101: 1644–55 19 Infection prevention and control of epidemic- and pandemic- prone acute respiratory infections in ... in severeacute respiratory distress syndrome NEJM 2013;368:2159-68 42 Sud S, Friedrich JO, Taccone P, et al Prone ventilation reduces mortality in patients with acute respiratory failure and severe...
... prevalence of kwashiorkor, the current practice of providing high doses of vitamin A as part of the inpatient management is questionable in the face of evidence demonstrating increased risk of mortality ... Hallam A: Management ofsevereacute malnutrition in children Lancet 368(9551)(pp 1992-2000), 2006 Date of Publication: 02 Dec 2006 2006 Heikens GT: How can we improve the care of severely malnourished ... serious shortcoming of our study Lack of key socio-demographic data might have limited our understanding of the impact such factors play on the outcome of children Exclusion of children admitted...
... absorption of fats and carbohydrates [5] In spite of their widespread use and the lack of credible reports regarding adverse effects, controversy has existed regarding the safety of bitter orange ... and is not a constituent of C aurantium Because of the known cardiovascular effects of nor-epinephrine and ephedrine, it has generally been assumed that consumption of p-synephrine and bitter ... increases in heart rate and blood pressure [8-11] The purpose of this study was to determine the effects of the acute administration of a product containing caffeine from guarana, p-synephrine...
... • The success of pediatric liver transplantation has made the recognition of the importance of nutritional support in the pretransplant period imperative to optimize the success of the transplant ... correlate with the degree of vitamin or trace mineral deficiency or the degree of hepatic dysfunction Nutritional Assessment of the Child with Liver Disease • A number of obstacles complicate the ... provide only 7-14% of calories as linoleic acid • To prevent EFA deficiency, at least 3-4% of calories should be linoleic acid • If cholestasis is severe enough to allow 30-40% of dietary fat to...
... dysplasia includes an evaluation of the presence of an asymmetry of fat folds of the thigh and buttocks; a Trendelenburg’s sign; limitations of passive range of motion in all directions, including ... external rotation of the tibia occurs by years of age, with an additional degree per year occurring up until skeletal maturity for a final average of 28 of external rotation [85] Because of this lateral ... addition, children who have severe spasticity are often nonambulatory The combination of a lack of ambulation and asymmetric muscle forces at the hip can exacerbate abnormalities of the femoral head...
... Frothy appearance ofacute sinusitis in the maxillary sinus Opacification of the ethmoid sinuses Opacification of the sphenoid sinuses Fluid in the right mastoid air cells Courtesy of Dr Hines-Peralta ... Pre-contrast Midline shift Compression of the anterior horn of the lateral ventricle Compression of the left posterior horn of the lateral ventricle Diffuse effacement of the cortical gyri shown best ... Courtesy of Dr Hines-Peralta and Nadalo and Hunter, 2004 Naana Afua Jumah, HMS III Gillian Lieberman, MD Summary of Patient BE • 11 year old girl with symptoms of sinusitis suspected of having complications...