severe acute allergic and immunological reactions i urticaria angioedema mastocytosis and anaphylaxis
Báo cáo khoa học: Phosphorylation of the arginine/serine dipeptide-rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation inhibitory activity and cellular localization pptx
... motif is directly involved in N protein selfinteraction [42] However, other evidence indicated that the RS motif interferes with SARS-CoV N protein multimerization but this activity requires its ... phosphorylation of the SARS-CoV N protein Our data provide evidence that phosphorylation of the N protein primarily occurs within its RS-rich motif and may affect its oligomerization, translation inhibitory ... rich in arginine residues and is likely cell cycle-dependent [20,35,36] The avian infectious bronchitis virus N protein indeed interacts with and colocalizes with the nucleolar proteins nucleolin...
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Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot
... pneumonitis were inconsistent because of inconsistencies in the criteria used to define radiation pneumonitis, heterogeneity in patient populations, and differences in treatment regimens and radiotherapy ... radiation pneumonitis The diagnosis of radiation pneumonitis is established by a history of radiotherapy, radiographic evidence (ground-glass opacity, or consolidation changes within the radiation ... supine with arms above their heads) and immobilized by using a patient fixation device (Pelvicast Base Plate, 35781-N1, Orfit industries) to improve the setup reproducibility during CT simulation...
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Báo cáo khoa học: " Prognosis for long-term survival and renal recovery in critically ill patients with severe acute renal failure: a population-based stud" pps
... similar multi-disciplinary critically ill populations One potential limitation of this case-definition is defining what factors contribute to the decision by the attending intensivist to initiate ... patients and those with pre-existing co-morbidities are at highest risk • A diagnosis of sARF is associated with high mortality and pre-existing co-morbidities, liver disease, higher APACHE II ... glomerular, and (4%) interstitial etiologies Toxic exposures included parenteral radiocontrast media in 107 (45%), aminoglycosides in 47 (20%) and amphotericin B in 10 (4%) The indications for institution...
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Báo cáo khoa học: " Using simulation for training and to change protocol during the outbreak of severe acute respiratory syndrome" ppsx
... high-fidelity simulation to design a modified practice of cardiac arrest resuscitation for an 'at risk of contamination' situation and to train caregivers as individuals and as a team Simulation ... remaining nurses and respiratory therapists Subsequent simulations involved only basic cardiopulmonary resuscitation and intubation because hospital policy mandates defibrillation by physicians ... there was minimal scientific evidence, and there were no guidelines, for decisions related to having HCWs apply protective equipment that would delay time to definitive ACLS care The Critical Care...
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Báo cáo khoa học: " Social support during intensive care unit stay might improve mental impairment and consequently health-related quality of life in survivors of severe acute respiratory distress syndrome" pps
... containing the following dimensions: somatization, obsessive-compulsive, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety, paranoid ideation, and psychoticism [17] These scales ... perceived social support during the ICU stay and during the rehabilitation period was associated with a decrease in PTSD symptoms In addition, 'high-scoring patients', indicating an increased risk of ... numbing and physiological hyperarousal Weinert and colleagues characterized traumatic events in the ICU setting in detail They include hallucinations, paranoia, ICU noise, severe sleep disruption,...
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Báo cáo y học: "Management of Critically Ill Patients with Severe Acute Respiratory Syndrome (SARS)"
... superimposed infections, too rapid tailing of corticosteroids or persistently severe and uninhibited cytokine storm Empirical anti-pseudomonal antibiotics should then be given first If there is ... and preventing the replication of viral RNA Ritonavir inhibits lopinavir metabolism thus increasing its serum concentration, but it has no activity against SARS-CoV In a retrospective analysis ... as possible after Int J Med Sci 2004 1(1): 1-10 diagnosis, and even empirically if suspicious clinical features and especially epidemiological links are present Since critically ill patients are...
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Tài liệu Allergic and Non‐Allergic Sinusitis for the Primary Care Physician: Pathophysiology, Evaluation and Treatment pdf
... connective tissue disease or immunodeficiency, including HIV, are also at risk. All these factors should be kept in mind. DIFFERENTIATING VIRAL URI, ACUTE SINUSITIS AND CHRONIC SINUSITIS Primary care physicians often diagnose and treat patients with acute bacterial sinusitis. Typically, the patient ... objective and patient‐based measures in patients diagnosed with recurrent acute sinusitis before and after surgical 31 intervention, in comparison to patients with chronic rhinosinusitis requiring surgery.(9) Patients with recurrent acute rhinosinusitis were less likely to have asthma or previous sinus surgery. Patients with chronic rhinosinusitis ... 2008 Aug; 139(2):198‐205. Rhinitis symptoms and comorbidities in the United States: burden of rhinitis in America survey 9. Anand VK. Epidemiology and economic impact of rhinosinusitis. Ann Otol RHinol Laryngol Supp 2004 May;193:3‐5. ...
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Tài liệu COMMUNITY-BASED MANAGEMENT OF SEVERE ACUTE MALNUTRITION doc
... Proteins Lipids Sodium Potassium Calcium Phosphorus (excluding phytate) Magnesium Iron Zinc Copper Selenium Iodine Vitamin A Vitamin D Vitamin E Vitamin K Vitamin B1 Vitamin B2 Vitamin C Vitamin ... malnutrition Prevention first… Investing in prevention is critical Preventive interventions can include: improving access to high-quality foods and to health care; improving nutrition and health ... interventions aimed at identifying and treating children in all parts of the country and at all times of the year through effective community mobilization and active case finding • Provide training and...
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Management of acute upper and lower gastrointestinal bleeding potx
... emphasis on identifying the sick patient with life threatening haemodynamic compromise and initiating appropriate resuscitation (see section 4.2) Certain clinical features associated with GI bleeding ... RESUSCITATION AND INITIAL MANAGEMENT 4.2.2colloid and crystalloid fluids No studies of sufficient quality comparing crystalloid and colloid fluid restoration were identified in patients with GI ... Localisation techniques utilise endoscopic, radiological and nuclear scintigraphic modalities The quantity of evidence on which this practice is based is limited Few studies have compared diagnostic...
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Báo cáo khoa học: On the mechanisms of bananin activity against severe acute respiratory syndrome coronavirus pptx
... helicase mutant is fully active is consistent with the above hypothesis proposing that this amino acid substitution, which is critical for bananin binding, does not interfere in the interaction ... effectively interferes with SARS-CoV ATPase activity by inhibiting helicase activity Furthermore, in a cell culture system of SARS-CoV, bananin inhibited viral replication at a half maximal effective ... that this mutation site is very far from the active site suggests that S259 is located either in an allosteric site of the enzyme or in a critical position for the overall protein flexibility The...
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Diagnosis and initial management of acute stroke and transient ischaemic attack (TIA) ppt
... responsibility of local commissioners and/ or providers Commissioners and providers are reminded that it is their responsibility to implement the guidance, in their local context, in light of their ... (‘Understanding NICE guidance’) NICE clinical guidelines are recommendations about the treatment and care of people with specific diseases and conditions in the NHS in England and Wales This guidance ... sudden and sometimes dramatic impact on the patient and their family, who need continuing information and support Clinicians dealing with acute care need to be mindful of the rehabilitation and...
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Báo cáo sinh học: " The Severe Acute Respiratory Syndrome (SARS)-coronavirus 3a protein may function as a modulator of the trafficking properties of the spike protein" docx
... their interactions with host factors Indeed, it is crucial to determine how this unique pathway benefits replication of the SARS-CoV It is also interesting to note that sequence comparison of isolates ... genetics would certainly reveal more about the interplay between 3a and S during SARS-CoV infection Implication of the hypothesis This hypothesis, if proven, will indicate that the interaction ... understand the different signaling pathways that are important for regulating the trafficking properties of S Indeed, the dilysine endoplasmic reticulum retrieval signal, which is a different...
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báo cáo hóa học:" The Severe Acute Respiratory Syndrome (SARS)-coronavirus 3a protein may function as a modulator of the trafficking properties of the spike protein" docx
... their interactions with host factors Indeed, it is crucial to determine how this unique pathway benefits replication of the SARS-CoV It is also interesting to note that sequence comparison of isolates ... genetics would certainly reveal more about the interplay between 3a and S during SARS-CoV infection Implication of the hypothesis This hypothesis, if proven, will indicate that the interaction ... understand the different signaling pathways that are important for regulating the trafficking properties of S Indeed, the dilysine endoplasmic reticulum retrieval signal, which is a different...
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báo cáo hóa học:" Women''''s quality of life is decreased by acute cystitis and antibiotic adverse effects associated with treatment" pptx
... recommendations for empiric antimicrobial therapy for acute uncomplicated cystitis Our findings support those of a previously published study, indicating that uncomplicated cystitis has a significant, ... the initial failure QOL at baseline was not different between patients with positive or contaminated urine cultures However, QOL did differ significantly at baseline between patients with positive ... antibiotic for empiric treatment of cystitis After obtaining written informed consent, patients provided a urine specimen for culture and sensitivity Patients were then randomized, using a random number...
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Báo cáo toán học: "Sets of Points Determining Only Acute Angles and Some Related Colouring Problems" pot
... (δ j i − δ ki )(δ li − δ ki ) (δ j i − δ ki )(δ li − δ ki ) (δ j i − δ ki )(1 + δ li − δ ki ) (δ li − δ ki )(1 + δ j i − δ ki ) (δ li − δ ki )(δ j i − δ ki − 1) (δ j i − δ ki )(δ li − δ ki − 1) ... − v i = for each i, ≤ i ≤ d Thus u, v, w is a right triple i ui , v i , w i is neither 0, 1, nor 1, 0, for any i, ≤ i ≤ d Since ui , v i , w i can take eight different values, this occurs independently ... ki are independent and -uniformly distributed, so by lemmas 3.7 and 3.6 and corollary 3.6.1, the distribution of the (v j i − v ki )(v li − v ki ) has positive bias, and by repeated application...
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Báo cáo y học: "Lamivudine treatment for severe acute HBV hepatitis" ppsx
... against 21.6% in controls) The lack of a control group is certainly a limitation but according to recent guidelines treatment is indicated for patients with fulminant hepatitis B and those with ... antiviral treatment shortens and improves the symptomatic phase of infection and allows a ready clinical and biochemical improvement On the other hand, when patients with end stage liver disease ... achieving a rapid viral clearance and clinical improvement All patients were discharged by the hospital, in spite of disease severity at presentation, within 13 days from the start of oral antiviral...
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Báo cáo y học: "Long-term benefits of omalizumab in a patient with severe non-allergic asthma" ppt
... incubation with omalizumab of bronchial tissue from asthmatic patients, inhibits specific and aspecific bronchial hyper-responsiveness This effect should be related to the inhibition of bronchial ... over time and a change in questionnaire score of 0.5 or more points has been determined to be the minimal clinically important difference [8] In our patient the quality of life improved significantly, ... Effectiveness; GINA: Global Initiative for Asthma; IgE: Immunoglobulin E; QoL: Quality of Life Authors’ contributions FM coordinated diagnostic and therapeutic stages and was one of the principal...
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Báo cáo khoa học: " SemiCytokines levels, Severity of acute mucositis and the need of PEG tube installation during chemo-radiation for head and neck cancer a prospective pilot study" ppt
... of inflammatory cytokines IL-1, IL-6, IL-8, TNF-a and the antiinflammatory cytokine IL-10 This evaluation was done with DPC’s ELISA kits in the quantitative “sandwich” enzyme immunoassay technique ... cytokines are correlated with severe mucositis Our study dealt with the reaction of healthy tissues to ionizing irradiation and not in tumors A similar finding was observed in a study published ... between IL1, TNF-a, and IL-10 levels and mucositis IL-10 is known as an anti-inflammatory cytokine [17], but we did not find any significant changes in IL-10 levels during radio-chemotherapy In some...
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Báo cáo khoa học: "Large volume unresectable locally advanced nonsmall cell lung cancer: acute toxicity and initial outcome results with rapid arc" potx
... years, ii) PS 1-2, iii) minimum weight loss (> 10% months before diagnoses All patients received a planning CT scan and were immobilized in a supine position within a personal bodyfix pillow During ... Radiation Oncology, IRCCS Istituto Clinico Humanitas, Milano (Rozzano), Italy 2Department of Clinical Oncology, IRCCS Istituto Clinico Humanitas, Milano (Rozzano), Italy 3Medical Physics Unit, ... reference in our institute Discussion Despite an improvement in survival the prognosis of patients with unresectable local advanced NSCLC (stage IIIA-IIIB) remains poor both for locoregional failure and...
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báo cáo khoa học: "Acute dyspnoea and single tracheal localisation of mantle cell lymphoma" ppsx
... Zaccaria A, Cantonetti AM, Gentilini P, Guardigni L, Gherlinzoni F, Ribersani M, Bendandi M, Albertini P, Tura S: Nongastrointestinal low- Submit your next manuscript to BioMed Central and take ... accurate diagnosis by correlating anatomo-pathologist and cytogenetic exams so as not to underestimate the incidence of atypical MCL in cancer/MALT localisation This case illustrates the necessity ... Amemiya M, Takise A, Kaira K, Endou K, Horie T, Inazawa M: Obstructive sleep apnea syndrome in a patient with superior vena cava syndrome caused by malignant lymphoma Nihon Kokyuki Gakkai Zasshi...
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