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senescence of human umbilical cord blood derived stem cells role of histone deacetylase inhibition through regulating micrornas

Báo cáo y học:

Báo cáo y học: " Intratracheal transplantation of human umbilical cord blood-derived mesenchymal stem cells attenuates " pps

Báo cáo khoa học

... the treatment of ALI Among the various sources of stem cells, human umbilical cord blood (UCB) provides readily available MSCs with low immunogenicity [11-13] Therefore, human UCB -derived MSCs ... Intratracheal transplantation of human umbilical cord blood derived mesenchymal stem cells dose-dependently attenuates hyperoxia-induced lung injury in neonatal rats Cell Transplant 2011 Cordero L, Rau R, ... doi:10.1186/1465-9921-12-108 Cite this article as: Kim et al.: Intratracheal transplantation of human umbilical cord blood- derived mesenchymal stem cells attenuates Escherichia coli-induced acute lung injury in mice...
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Báo cáo sinh học:

Báo cáo sinh học: " Human umbilical cord blood-derived mononuclear cell transplantation: case series of 30 subjects with Hereditary Ataxia'''' docx

Hóa học - Dầu khí

... Remyelination by Cord Blood Stem Cells after Spinal Cord Injury J Neurotrauma 2007, 24(2):391-410 doi:10.1186/1479-5876-9-65 Cite this article as: Yang et al.: Human umbilical cord blood- derived mononuclear ... YG, Cho TH: Transplantation of Umbilical Cord Blood Stem Cells for Treating Spinal Cord Injury Stem Cell Rev 2011, 7(1):181-194 34 Dasari VR, Spomar DG, Gondi CS, Sloffer CA, Saving KL, Gujrati ... Intravenous administration of human umbilical cord blood cells in a mouse model of amyotrophic lateral sclerosis: distribution, migration, and differentiation J Hematother Stem Cell Res 2003, 12(3):255-270...
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báo cáo hóa học:

báo cáo hóa học:" Human umbilical cord blood-derived mononuclear cell transplantation: case series of 30 subjects with Hereditary Ataxia" pdf

Hóa học - Dầu khí

... Remyelination by Cord Blood Stem Cells after Spinal Cord Injury J Neurotrauma 2007, 24(2):391-410 doi:10.1186/1479-5876-9-65 Cite this article as: Yang et al.: Human umbilical cord blood- derived mononuclear ... YG, Cho TH: Transplantation of Umbilical Cord Blood Stem Cells for Treating Spinal Cord Injury Stem Cell Rev 2011, 7(1):181-194 34 Dasari VR, Spomar DG, Gondi CS, Sloffer CA, Saving KL, Gujrati ... Intravenous administration of human umbilical cord blood cells in a mouse model of amyotrophic lateral sclerosis: distribution, migration, and differentiation J Hematother Stem Cell Res 2003, 12(3):255-270...
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Báo cáo khoa học:

Báo cáo khoa học: "In vitro neuronal and osteogenic differentiation of mesenchymal stem cells from human umbilical cord blood" ppt

Báo cáo khoa học

... tnecseroulf gniwollof ehT SBP htiw semit eerht desnir erew selpmas ehT Co73 ta h rof sllec eht htiw detabucni erew seidobitna yramirp ehT ylevitcepser ,PAFG rof 002 : dna ESN rof 002 : ta ares ... 001-X notirT %4.0 neht dna ,nim rof enoteca %001 ,nim 01 rof lonahtem %001 dloc eci htiw detaert neht erew yehT erutarepmet moor ta nim 01 rof SBP ni edyhedlamrof %7.3 htiw dexif neht dna SBP ... llec gnimrofrep dna esu lacinilc rof SBF gnisu tuohtiw oviv xe sCSM dnapxe ot sdohtem dnif ot deen ew dna ,hcraeser ruo rof SBF desu ew ,yduts tneserp ni ,revewoH noitarefilorp sCSM rof noitidnoc...
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Báo cáo khoa học:

Báo cáo khoa học: "Transplantation of canine umbilical cord blood-derived mesenchymal stem cells in experimentally induced spinal cord injured dogs" pot

Báo cáo khoa học

... ’slaminA yrotarobaL fo esU dna eraC eht rof ediuG‘ eht fo senilediug eht ot gnidrocca demrofrep saw noitagitsevni sihT yduts yrujni droc lanips latnemirepxe eht rof desu erew ,gk 95.0 ± 77.3 dehgiew ... wef a ,revewoh ;noitamrof ytivac fo egatnecrep tsellams eht detartsnomed puorg PC eht ,noitidda nI spuorg GBCU dna CSM-BCU eht ni noitamrof ytivac fo egatnecrep rellams a dnuof ew ,sllec mets detnalpsnart ... sllec detnalpsnart eht rof troppus reffo yam droc derujni eht ,droc lanips eht fo sdne lamixorp dna latsid eht ot noitcennoc rof ,slairetam ro sllec suoirav fo pu edam dloffacs ro egdirb a htiw...
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Báo cáo khoa học:

Báo cáo khoa học: "Implantation of canine umbilical cord blood-derived mesenchymal stem cells mixed with beta-tricalcium phosphate enhances osteogenesis in bone defect model dogs" ppsx

Báo cáo khoa học

... tendencies in mesenchymal stem cells from human bone marrow and umbilical cord blood Stem Cells 2006, 24, 679-685 Chen L, Tredget EE, Wu PYG, Wu Y Paracrine factors of mesenchymal stem cells recruit macrophages ... osteoblast progenitors from umbilical cord blood stem cells by BIO-PLEX technology Cell Biol Int 2008, 32, 320-325 27 Rogers I, Casper RF Umbilical cord blood stem cells Best 393 Pract Res Clin ... values are means ± SD Fig Lateral radiographs of antebrachium at 0, 4, 8, and 12 weeks after first injection of canine umbilical cord blood derived stem cells was decreased by weeks after injection...
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Báo cáo khoa học:

Báo cáo khoa học: " Isolation and characterization of canine umbilical cord blood-derived mesenchymal stem cells" pps

Báo cáo khoa học

... commonly observed in human umbilical cord blood derived MSCs [4] A rapid growth rate is an intrinsic aspect of cultured cUCB-MSCs [4] Cytotherapy using human umbilical cord blood stem cells frequently ... experimental analysis A guarantee of enough numbers of multipotent stem cells out of a very small quantity of cord blood sample from the canine umbilical cord blood is attractive In conclusion, ... and characterization of canine umbilical cord blood- derived mesenchymal stem cells 22 23 24 25 26 27 28 29 30 Ryu HM Mesenchymal progenitor cells in the human umbilical cord Ann Hematol 2004,...
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Immunological characterization of human umbilical cord lining derived cells and their therapeutic application in a diabetic mouse model

Immunological characterization of human umbilical cord lining derived cells and their therapeutic application in a diabetic mouse model

Cao đẳng - Đại học

... characterization of a novel primary epithelial cell-type from the human umbilical cord Two types of cells can be derived from the umbilical cord lining membrane, termed cord lining epithelial cells (CLECs) ... treatment of a type diabetes mouse model   xiv LIST OF FIGURES AND TABLES Figure 3.1 Schematic of human umbilical cord and the isolation of cord lining cells 51 Figure 3.2 Schematic of mixed leukocyte ... Placental stem cells ……………………………………………………34 2.4.3.1 Amniotic epithelial cells ………………………………………35 2.4.3.2 Amniotic mesenchymal cells ………………………………….37 2.4.4 Umbilical cord blood stem cells ………………………………………39...
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Báo cáo y học:

Báo cáo y học: "Human infrapatellar fat pad-derived stem cells express the pericyte marker 3G5 and show enhanced chondrogenesis after expansion in fibroblast growth factor-2" potx

Báo cáo khoa học

... staining of IPFPderived cells It was therefore interesting that they showed a pattern of expression on a high proportion of the IPFP -derived cells and of epitopes commonly abundant on adult stem cells ... Clonal IPFP -derived cells retained the cell surface characteristics of the parent IPFP cells, which were similar to mesenchymal stem cells The clonal populations of IPFP -derived cells appeared ... characterisation of infrapatellar fat padderived cells The rate of proliferation of the IPFP -derived cells in monolayer culture was significantly increased by FGF-2 A comparison of their proliferation...
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Báo cáo y học:

Báo cáo y học: "Sphingosine-1-phosphate promotes the differentiation of human umbilical cord mesenchymal stem cells into cardiomyocytes under the designated culturing conditions" pdf

Báo cáo khoa học

... Review: Human Umbilical Cord Stroma with Regard to the Source of Fetus -Derived Stem Cells Stem cells 2007, 25:2886-2895 Wu KH, Mo XM, Zhou B, Lu SH, Yang SG, Liu YL, Han ZC: Cardiac potential of stem ... cardiomyocytes sheets from differentiated human umbilical cord mesenchymal stem cells We assessed viability of the cells of sheets at room temperature No indication of cell apoptosis was noticed from ... stem cells from whole human umbilical cord tissue J Cellular Biochem 2009, 107:926-932 Yang C-C, Shih Y-H, Ko M-H, Hsu S-Y, Cheng H, Fu Y-S: Transplantation of Human Umbilical Mesenchymal Stem Cells...
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báo cáo khoa học:

báo cáo khoa học: "Effect of anti-CD52 antibody alemtuzumab on ex-vivo culture of umbilical cord blood stem cells" doc

Báo cáo khoa học

... Expansion of umbilical cord blood for clinical transplantation Curr Stem Cell Res Ther 2007, 2(4):324-335 Hofmeister CC, Zhang J, Knight KL, Le P, Stiff PJ: Ex vivo expansion of umbilical cord blood stem ... cells Effects of alemtuzumab on total nucleated cells and CD34+ cells 100,000 CD34+ cells were cultured in ml StemSpan™ SFEM Medium supplemented with 10% of healthy human serum, 50 ng/ml of stem ... transplantation: marrow or umbilical cord blood? Blood 2003, 101(11):4233-4244 Huang S, Law P, Young D, Ho AD: Candidate hematopoietic stem cells from fetal tissues, umbilical cord blood vs adult bone...
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Báo cáo y học:

Báo cáo y học: "Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis" pps

Báo cáo khoa học

... Yao R, Tuan RS: Comparison of proliferative and multilineage differentiation potential of human mesenchymal stem cells derived from umbilical cord and bone marrow Stem Cells 2007, 25:1384-1392 ... Weiss RJ, VanderWerff I, Troyer D, McIntosh KR: Immune properties of human umbilical cord Wharton’s jelly -derived cells Stem Cells 2008, 26:2865-2874 Arnett FC, Edworthy SM, Bloch DA, McShane ... doi:10.1186/ar3187 Cite this article as: Liu et al.: Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis Arthritis Research & Therapy 2010 12:R210...
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báo cáo hóa học:

báo cáo hóa học:" Stem cells from umbilical cord blood do have myogenic potential, with and without differentiation induction in vitro" pdf

Hóa học - Dầu khí

... differentiation of mesenchymal stem cells isolated from human umbilical cord blood Stem Cells 2004, 22(4):617-624 Nunes VA, Cavaçana N, Canovas M, Strauss BE, Zatz M: Stem cells from umbilical cord blood ... low expression of dystrophin in co-cultures (data not shown) Transdifferentiation of CD34+ stem cells into muscle cells During the expansion of CD34+ stem cells from umbilical cord blood, we observed ... Materials and methods Isolation and characterization of human CD34+ cells from the umbilical cord blood CD34+ stem cells from human umbilical cord were obtained from healthy babies, born in Hospital...
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báo cáo hóa học:

báo cáo hóa học:" Birth weight and characteristics of endothelial and smooth muscle cell cultures from human umbilical cord vessels" docx

Hóa học - Dầu khí

... vascular cell types obtained from human umbilical cords (UCs) Cell proliferation kinetics of vascular cell types obtained from human umbilical cords (UCs) Human umbilical artery and vein endothelial ... http://www.translational-medicine.com/content/7/1/30 Figure Projection area of human umbilical artery and vein endothelial cells grown to confluence Projection area of human umbilical artery and vein endothelial cells grown to confluence Passage ... receiving the impact of the fetal milieu The UC is an exceptional source of vascular cells, which can offer valuable information about the cellular characteristics of the blood vessels of the individual...
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Báo cáo hóa học:

Báo cáo hóa học: "Safety evaluation of allogeneic umbilical cord blood mononuclear cell therapy for degenerative conditions" pot

Hóa học - Dầu khí

... of allogeneic cord blood therapy in absence of immune suppression/myeloablation This study presents for the first time a detailed safety analysis of using non-matched, allogeneic cord blood cells ... DA: Autologous umbilical cord blood transfusion in very young children with type diabetes Diabetes Care 2009, 32:2041-2046 Harris DT: Non-haematological uses of cord blood stem cells Br J Haematol ... Intravenous administration of human umbilical cord blood cells in a mouse model of amyotrophic lateral sclerosis: distribution, migration, and differentiation J Hematother Stem Cell Res 2003, 12:255-270...
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Báo cáo khoa học:

Báo cáo khoa học: "Functional recovery and neural differentiation after transplantation of allogenic adipose-derived stem cells in a canine model of acute spinal cord injury" potx

Báo cáo khoa học

... after human umbilical cord blood cells transplantation with brain -derived neutrophic factor into the spinal cord injured rat Acta Neurochir (Wien) 2005, 147, 985-992 Lee JM Evaluation of spinal cord ... the end of the study, with moveable joints of the pelvic limbs This score at weeks was lower than that a previous report (Olby score; 7.4) that used umbilical cord blood- derived stem cells [22] ... Lee YW, Kim WH, Kang KS, Kweon OK Transplantation of canine umbilical cord blood- derived mesenchymal stem cells in experimentally induced spinal cord injured dogs J Vet Sci 2007, 8, 275-282 Ma...
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Báo cáo y học:

Báo cáo y học: "Clinical observations on intensive immunosuppressive therapy combined with umbilical cord blood support for the treatment of severe aplastic anemia" ppt

Báo cáo khoa học

... count of the transfused cord blood was 2.25-15.1 × 107 cells/ kg with a median MNC count of 4.0 × 10 cells/ kg Two patients weighing over 80 kg were given double units of the umbilical cord blood ... for severe acquired aplastic anemia Blood 1995, 85:3058-3065 Knudtzon S: In vitro growth of granulocyte colonies from circulating cells in human cord blood Blood 1974, 43:357-361 Zi-Min Sun, Hui-Lan ... units of the umbilical cord blood transfusion HLA matching and blood typing were performed for umbilical cord blood selection, and cord blood units with 1-3 HLA typing mismatches were selected G-CSF...
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Báo cáo khoa học:

Báo cáo khoa học: "Regeneration of human bones in hip osteonecrosis and human cartilage in knee osteoarthritis with autologous adipose-tissue-derived stem cells: a case series" docx

Báo cáo khoa học

... approximately 40 cm3 of packed adipose tissue, fibrous tissue, red blood cells and a small number of nucleated cells An equal volume of digestive enzyme, 0.07% collagenase type 1, composed of several collagenases, ... mechanism of regeneration is not yet clear It could be through direct differentiation of stem cells that were introduced to the diseased joints Alternatively, it could be due to the tropic effects of ... showed osteonecrosis of the femoral head, stage Since there is no effective non-surgical Page of treatment of the disease, she elected to receive stem cell treatment At the time of initial evaluation,...
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Báo cáo y học:

Báo cáo y học: "Histone deacetylase inhibition accelerates the early events of stem cell differentiation: transcriptomic and epigenetic analysis" doc

Báo cáo khoa học

... importance of histone acetylation on ES cell differentiation, we treated cells with the histone deacetylase inhibitor TSA and examined gene expression changes using Results Inhibition of histone deacetylase ... R65 days Figure of Analysis bulk histone modifications in TSA-treated ES cells and EBs Analysis of bulk histone modifications in TSA-treated ES cells and EBs Global levels of histone H3 acetylation ... important roles in stem cell identity [24,25], but may also guide differentiation and fate decisions [26,27] To examine the role of histone acetylation on the differentiation state of mouse ES cells, ...
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Báo cáo khoa học: Differential effects of histone deacetylase inhibitors on phorbol ester- and TGF-b1 induced murine tissue inhibitor of metalloproteinases-1 gene expression docx

Báo cáo khoa học: Differential effects of histone deacetylase inhibitors on phorbol ester- and TGF-b1 induced murine tissue inhibitor of metalloproteinases-1 gene expression docx

Báo cáo khoa học

... The packaging of eukaryotic DNA into chromatin plays an important role in regulating gene expression The DNA is wound round a histone octamer consisting of two molecules each of histones H2A, ... modification of histones, via acetylation, methylation and phosphorylation [15–18] Acetylation by histone acetyltransferases (HATs) occurs on specific lysine residues on the N-terminal tails of histone ... h of stimulation As the kinetics of c-fos induction so clearly preceded that of Timp-1, we analysed the expression of Timp-1 in c-fos deficient mouse fibroblasts (Fig 5A) Surprisingly, mouse cells...
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