segmentation assisted registration for brain mr images
nanotechnology for cancer therapy, 2007, p.810
... carriers for defined release of anti-tumor agents, as well as very useful for targeted delivery of such molecules as contrast agents for tumor imaging Dendritic nanocarriers have been evaluated for ... and nanoplatforms, Nanotechnology for Cancer Therapy cannot possibly cover each nanoscale application that has potential for use in anti-tumor therapy and tumor imaging One nanoplatform that should ... received attention for their utility as tunable multicolor nanoparticles that can be used for in vivo tumor imaging in animal models of cancer as well as for multiplex detection of mRNAs and proteins...
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báo cáo hóa học: " In vitro and in vivo pre-clinical analysis of a F(ab’)2 fragment of panitumumab for molecular imaging and therapy of HER1-positive cancers" pot
... concentration for 50% inhibition (IC50 ) for intact panitumumab IgG was 0.5 nM while the IC50 for the panitumumab F(ab’)2 was nM Evaluating the potential of the panitumumab F(ab’)2 for clinical ... milliliter (%ID/mL) was calculated for each of the samples and the average with the standard deviation plotted for each time point Imaging g-Scintigraphy was performed with tumor bearing mice to ... was performed as previously described [32] Radio-iodination of panitumumab (50 μg) with Na125I (0.5-1 mCi; PerkinElmer, Shelton, CT, USA) was performed using Iodo-Gen (Pierce Chemical, Rockford,...
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Surface functionalization of superparamagnetic iron oxide nanoparticles for potential cell targeting, imaging, and cancer therapy applications
... PLMA-2-SPIONs and (b) PLMA-1PEG-3-SPIONs (for all plots, correlation coefficient R2 > 0.97) Relaxometric measurements were performed by MRI. Figure 3-14 MR images of phantoms containing (a) macrophages ... Therefore, the bio-interfaces of SPIONs are crucial for their biomedical applications The overall aim of this thesis is to modify SPIONs with different polymers for potential cell targeting, MRI ... especially Dr Yuan Zeliang, Mr Chia Phai Ann, Dr Yang Liming, Ms Xu Yanfang and Mr Chan Chuin Mun for their kindly help during my research The research scholarship for Ph.D study provided by National...
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Molecular Imaging: An Essential Tool in Preclinical Research, Diagnostic Imaging, and Therapy potx
... relatively high for viral RNA in infected cells, but as a rule, the mRNA coding for a given protein is less abundant than the protein itself Abundant mRNAs such as the one coding for tyrosine hydroxylase ... the gene expression in the brain (Shi et al 2000) Brain sections clearly showed an accumulation of the iodinated PNA in brain tumors This study suggests that gene brain imaging can be realized ... oligonucleotides to the in vivo context differ somewhat for aptamers and for antisense Target accessibility is much less of a problem for aptamers than for antisense Many aptamer targets are extracellular...
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The use of gold nanostructures in the imaging and therapy of cancer
... to Mr Chow Tzu Hao, Mr Song Kin San and Dr Ng Beng Koon from the photonics group in the School of Electrical and Electronics Engineering, NTU for making their benchtop OCT system available for ... anionic species of the form [Au(OH)xCl4-x]¯ Whilst the pH is raised to by NaOH to form the dominant specie AuCl(OH)3¯ for DP process of seeding, the pH is raised to 10.1 by K2CO3 to form the dominant ... underlying the formation of OCT images renders their detection of incoherent fluorescence processes impossible Therefore, fluorescent based contrast agents that are commonly used for molecular...
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Báo cáo hóa học: " Both FA- and mPEG-conjugated chitosan nanoparticles for targeted cellular uptake and enhanced tumor tissue distribution" docx
... the resultant mixture, followed by stirring for 12 h at 37°C to form chemical cross-linking NPs, which were isolated by centrifugation at 12,000 rpm for 30 min; and the deposits (NPs) were then ... chitosan microspheres as drug carrier for prednisolone sodium phosphate as model for antiinflammatory drugs J Control Release 1996, 39:17 Tian XX, Groves MJ: Formulation and biological activity ... Preparation and evaluation as a matrix for controlled release of pharmaceuticals J Pharm Pharmcol 1992, 44:283 Gupta KC, Jabrail FH: Controlled-release formulations for hydroxy urea and rifampicin using...
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Báo cáo y học: "Rasburicase represents a new tool for hyperuricemia in tumor lysis syndrome and in gout Lisa Cammalleri and Mariano Malaguarnera"
... Syndrome (TLS) Already before 2002, when Food and Drugs Administration (FDA) of US has approved the use of 85 urate oxidase for the management of paediatric patients at risk for TLS (Tumor Lysis ... acid and acute arthritic attack PEG-uricase, the long-acting form, seems to better control gout that non-pegylated form The need for a daily administration and the increased probability of development ... than uric acid It may impair renal function and improve stone formation Its formulation is oral since 1966 Since 1999 a new intravenous formulation (not yet available in Italy) was introduced in...
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Báo cáo khoa học: Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis pptx
... peptide; glutamic acids residues 225 and 343 critical for heparanase enzymatic activity, are detonated (see text for details) (B) Colony formation in soft agar Control (Vo) heparanase (Hepa)-, ... is a target for therapy Results from studies using several in vivo model systems support the notion that enzymatic activities responsible for syndecan-1 modification are valid targets for myeloma ... prognosis and prolonged survival post operation [44–46,48] For example, 70% of the patients with salivary gland carcinoma that stained negative for heparanase were still alive 300 months (25 years)...
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adobe digital imaging how-tos 100 essential techniques for photoshop cs5, lightroom 3, and camera raw 6
... it’s a fact of life for anyone who captures thousands of images or video clips Another problem is that hard drive performance can taper off well before its capacity is reached For these reasons, ... all the information, image by image, is a recipe for frustration (Figure 3a) Metadata presets are a way to apply several pieces of IPTC information to many photographs at one time For example, ... that appears, and fill in the values for the fields that will apply to all the images that will use the preset As you enter the text for each item, the check box for that field will be selected automatically...
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patel, chellapa - sparse representations and compressive sensing for imaging and vision
... inverse Fourier transform In this way, one can view an MRI scanner as a machine that measures the information about the object in Fourier domain See [154] for an excellent survey on MRI 3.2 Compressive ... limitations of the MRI is the linear relation between the number of measured data and scan time As a result MRI machines tend to be slow, claustrophobic, and generally uncomfortable for patients It ... time The theory of CS can be used to reduce the scan time in MRI acquisition by exploiting the transform domain sparsity of the MR images [79], [80], [108] The standard techniques result in aliasing...
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báo cáo hóa học:" Comparative study of 64Cu/NOTA-[D-Tyr6,beta-Ala11,Thi13,Nle14]BBN(6-14) monomer and dimers for prostate cancer PET imaging" potx
... was used for coupling in amine-free DMF Fmoc-protected amino acids were activated for coupling with an equi-molar amount of HATU and two equivalents of DIEA Fmoc deprotection was performed in ... decreased for this tracer The uptake in the blood, kidney, liver, spleen, lungs and tumor is higher for 64Cu/NOTA-dimer A modest decreased uptake was observed at the PC3 tumor site for the dimer ... cellular uptake studies predicted higher tumor uptake for 64Cu/NOTA-monomer In fact, PC3 tumor uptake was higher for 64 Cu/NOTA-monomer for the first 30 post-injection Afterwards, the tumor uptake...
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Báo cáo y học: "Autologous chondrocyte implantation for cartilage repair: monitoring its success by magnetic resonance imaging and histology" ppt
... immunostaining for collagens (Fig 1c–g) MRI The mean time in days between biopsy and MRI scan was 15.5 ± 12.3 days, apart from two samples for which there were intervals of 76 and 110 days On MRI, the ... staining for types I and III collagens, patchy staining for type II collagen, and a little for type VI collagen Most glycosaminoglycan staining was for chondroitin-4-sulfate, with less for keratan ... biopsy specimen such as is used for histochemical assessment can provide only limited information, as it is from a discrete location MRI, in contrast, can provide information on the whole area In...
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Báo cáo khoa học: "Preoperative Y-90 microsphere selective internal radiation treatment for tumor downsizing and future liver remnant recruitment: a novel approach to improving the safety of major hepatic resections" docx
... contributions SG is the authorized user for Y-90 microsphere administration and performed the hepatic resection MH is the interventional radiologist who performed the Y-90 microsphere treatment ... 2) Liver function tests remained normal except for a mild elevation in alkaline phosphatase level The patient's physi- Page of (page number not for citation purposes) World Journal of Surgical ... systemic chemotherapy for a total of courses with no significant toxicity noted At 3month follow-up evaluation, based on a favorable tumor response, the patient's improved performance status, and...
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Báo cáo y học: "Expression of ADAM15 in rheumatoid synovium: up-regulation by vascular endothelial growth factor and possible implications for angiogenesis" ppt
... 62°C for ADAMs 8, 9, 10, 12, 17, 20, 21, 28 and 30, 67°C for ADAM15, 64°C for VEGFR-1, 63°C for VEGFR-2 and neuropilin-1 and 65°C for β-actin, and minute at 72°C, followed by minutes at 72°C for ... manufacturer's protocols Cycling conditions were 50°C for minutes, 95°C for 10 minutes, and then 40 cycles at 95°C for 15 seconds and 60°C for minute Primers were designed and selected using Primer ... searches were performed to confirm the specificity of the probes Hybridization with the probes was performed at 42°C for 16 h, and the sections were washed in 2× standard saline citrate/50% formamide,...
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Báo cáo khoa học: "Planning target volume margins for prostate radiotherapy using daily electronic portal imaging and implanted fiducial markers" docx
... foam support for lower legs Empty rectum and partially full bladder (drink 500 mL water 45 mins before) for CT and treatment ns 0.53 0.60 fiducial markers Daily pre-treatment portal images 3× per ... during the IMRT boost phase, during which daily on-line correction was performed according to fiducial marker position A mm factor was added in quadrature to the total error, to account for inaccuracies ... knee cushion Comfortably full bladder, empty rectum 0.57 0.79 0.77 fiducial markers, no correction of isocenter placement errors Margins required for 95% probability of CTV coverage for any given...
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Báo cáo khoa học: "Value of diffusion weighted MR imaging as an early surrogate parameter for evaluation of tumor response to high-dose-rate brachytherapy of colorectal liver metastase" docx
... Imaging was performed at three time points: Baseline MRI was performed at a mean of days (range: - 36 days) prior to CT- or MRI-guided HDRBT All but one patient received early MRI one to three ... minimal target dose prescribed for colorectal metastases was 19.4 ± 3.1 Gy (range: 10.3 - 24.0 Gy) MR Imaging Protocol Magnetic resonance imaging was performed with a 1.5 T MR system (Gyroscan, Intera, ... follow-up MRI compared to baseline MRI Boxplot illustrates changes of mean ADC of non-treated and treated colorectal liver metastases days (early MRI) as well as months (follow-up MRI) following...
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Báo cáo khoa học: "Stereotactic body radiotherapy for stage I lung cancer and small lung metastasis: evaluation of an immobilization system for suppression of respiratory tumor movement and preliminary results" ppsx
... SBRT is considered a therapeutic option in stage I NSCLC either for inoperable patients or for patients refusing surgery SBRT for lung cancer is under evaluation in clinical trials Japan Clinical ... scintigraphy and brain magnetic resonance imaging (MRI), or clinically diagnosed as recurrent or metastatic lung cancer; (2) tumor diameter ≤ 50 mm, and (3) World Health Organization performance status ... pulmonary functions were assessed before SBRT Respiratory functions were categorized as obstructive dysfunction when the ratio of forced expiratory volume in second to forced vital capacity (FEV 1.0%)...
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Báo cáo khoa học: " Ipsilateral irradiation for well lateralized carcinomas of the oral cavity and oropharynx: results on tumor control and xerostomia" pot
... 3D-CRT ipsilateral technique is simpler to perform and gives acceptable good results, it seams reasonable to reserve IMRT for more advanced stages for whom bilateral neck irradiation is deemed ... treatment using the Kaplan-Meier method A descriptive analysis was used for the toxicity data SPSS 16.0 for Windows was used for the statistical analysis Results Follow-up Patients were followed ... oncologists and head and neck surgeons performed a clinical examination A head and neck CT or MRI, examination under general anesthesia and/or biopsy were performed if recurrence was suspected Assessment...
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Báo cáo khoa học: " Kinetic modeling of tumor growth and dissemination in the craniospinal axis: implications for craniospinal irradiation" pps
... and brain compartments, respectively Scenario I In this scenario (Figure 3), results following a standard course of treatment for the model allowing for flow (Qf = 25 ml/hr) and not allowing for ... viable, and adhesion will account for only a portion of the cells cleared from the CSF This is accounted for in the model by incorporating modulating efficiency factors for transfer of viable cells ... difficult for cells to adhere to other cells when they are flowing in the CSF The values for kshed and kadh are both modulated by the values γf and γt, as described above The value for Qf, the...
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Báo cáo y học: "Targeted genomic capture and massively parallel sequencing to identify genes for hereditary hearing loss in middle eastern families" pot
... Clinical diagnosis is the cornerstone for treatment of human disease Elucidation of the genetic basis of human disease provides crucial information for diagnostics, and for understanding mechanisms of ... 69978, Israel Full list of author information is available at the end of the article thus far for non-syndromic sensorineural hearing impairment [1] and many more for syndromes including hearing ... responsible for 27% of congenital hearing loss among Israeli Jews [4] and 14% of congenital hearing loss among Palestinian Arabs [5] Each of the other known genes for hearing loss is responsible for...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008