safety and quality in the hematology laboratory
Báo cáo y học: "TPO, but not soluble-IL-6 receptor, levels increase after anagrelide treatment of thrombocythemia in chronic myeloproliferative disorders"
... for the purpose of cytokine levels and platelet counts, we have grouped PR and F together Laboratory methods Blood counts were performed in the routine of the hospital laboratories of clinical ... time points and months for the latter three variables Discussion We report here that serum levels of TPO, the major cytokine involved in the regulation of megakaryocyte and platelet growth and release, ... Serum and plasma samples were collected at baseline and after months of therapy and stored at –70oC until analyzed Only patients completing the months of therapy were included Serum TPO and soluble...
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Tài liệu TREATMENT OF EATING DISORDERS ppt
... years of clinical and training experience, Judith’s teaching and writing focuses on the integrative clinical treatment of eating disorders and on research-practice integration in the eating disorders ... women’s health and well-being, including the role of exercise in eating disorders treatment and recovery, the impact of sexual and self-objectification in girls’ and women’s daily lives, and the perpetuation ... families and the challenges families face in obtaining appropriate treatment Many women in her family have been affected by eating disorders, including her mother and daughter, nieces, and cousins In...
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Tài liệu Gynecological and obstetrical manifestations of inherited bleeding disorders in women docx
... menses [5,6] Furthermore, the release of prostaglandin E2, prostaglandin F2a and prostacyclin by the endometrium and myometrium during menstruation are increased in tissues obtained from menorrhagic ... antifibrinolytic (tranexamic acid and aminocaproic acid) and/ or DDAVP or desmopressin (1-desamino-8-D-arginine vasopressin), a synthetic vasopressin that stimulates the release of VWF from endothelial ... Thrombosis and Haemostasis In women with VWD, therapy should start on the first or second day of menses, with the specific therapeutic choice, dose, duration of therapy, and therapeutic monitoring [44] In...
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Tài liệu Male Reproductive Health Disorders and the Potential Role of Exposure to Environmental Chemicals pdf
... health, and highlight the difficulties inherent in establishing the relationships between these disorders and EC exposures – in particular the enormous practical issues and costs involved in trying ... TGCT 13 incidence is increasing in Finland (where the incidence has been low) but appears to be plateauing or even declining in Denmark (Moller 2001; Jacobsen et al 2006) Therefore, although the ... the edge of the glans or to the top of the penile shaft In moderate cases the meatus is located lower down the shaft and in severe cases lower still and perhaps even in the perineal region, the...
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Tài liệu Diseases and Disorders: Brain Trauma docx
... moment they are going about their lives—skating in an NHL game, enjoying a vacation on a South Seas island, painting the house, or walking point on a surveillance mission in Baghdad and the next they ... throwing them in the air, holding them upside down, swinging them around, or jumping up and down with them.” Regardless of the circumstances, Shaken Baby Syndrome can be devastating to the child ... connected by wires to the EEG machine The electrodes transmit the electrical activity in the brain into the EEG machine, which displays the brain’s activity in the form of wavy lines that appear on...
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Tài liệu Diseases and Disorders Acne docx
... peaceful the beach is, and how the sun warms my face and heals my skin I imagine the sun cleansing and clearing my skin from the outside, and my own body doing it from the inside In my mind, my skin ... accumulate in the follicles Then sebum empties onto the skin through tiny openings in the follicles called pores Here sebum protects the skin from bacteria that live on the skin by washing the bacteria ... pustules and cysts trapped below the surface of the skin to work their way to the surface of the skin, where they burst and heal Consequently, many patients find that their acne actually worsens in the...
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Tài liệu THERAPEUTICS of PARKINSON’S DISEASE and OTHER MOVEMENT DISORDERS docx
... contains a RING finger domain (comprising two RING finger motifs separated by an inbetween-RING domain) at the C-terminus The protein also contains a central linker region and a ubiquitin-like ... 2002) The Lewy body is usually 30 mm in diameter, and in the SNc in PD it demonstrates an intensely stained central core with a lightly staining surrounding halo with the protein-binding dye eosin ... was associated with the accumulation of a-synuclein and ubiquitin, and the formation of intracytoplasmic Lewy body-like inclusions containing these and other proteins Further, several studies...
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Tài liệu Molecular Neurobiology of Alzheimer Disease and Related Disorders doc
... enzymes, G protein and channel activities [47] Precursors in the n–6 series beginning with linoleic acid are used to synthesize AA and precursors in the n–3 series beginning with linolenic acid ... splicing in vivo The model for the mechanism of HMGA1ainduced aberrant exon skipping Hypoxia-induced HMGA1a protein binds to the conserved HMGA1a binding site (upstream of the 5Ј splice of the ... is eliminated in cells lacking S2P [14] Interestingly, when both S1P and S2P are involved in RIP, the transmembrane domain of the substrates seems to share type II topology On the other hand, when...
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Tài liệu SLEEP-RELATED BREATHING DISORDERS EXPERIMENTAL MODELS AND THERAPEUTIC POTENTIAL docx
... mechanical, including photocopying, microfilming, and recording, or by any information storage and retrieval system, without permission in writing from the publisher Current printing (last digit): 10 PRINTED ... breathing disorders The Lung Biology in Health and Disease series has played an important role in consolidating the accumulating knowledge in this area and in providing a focused view of the state ... breathing with central apnea led to the hypothesis that SRBD following brain injury resulted from a loss of supramedullary inhibition to an intrinsic brainstem oscillator (81) These findings again...
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Tài liệu Perspectives on Diseases and Disorders Malaria doc
... they had ingested DDT by licking themselves after rubbing against the walls of the sprayed buildings With no more cats in the sprayed villages, the rat population exploded, destroying crops and ... began living in large communities and the rainforest was being cut down for slash -and- burn agriculture Other findings also support the timeframe for the birth of the modern falciparum: there was ... dispatched to bring seeds and saplings back to Europe After arriving in South America, the quinine hunters endured a brutal trek through the snow-choked passes of the Andes and down into the cloud...
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Tài liệu RESPIRATORY CONTROL AND DISORDERS IN THE NEWBORN doc
... that occurs in plants being activated in the morning to protect plants from the heat of the sun and others being activated in the evening to protect them from cold temperatures and freezing! Cyclic ... disorders in the neonate often begins with cardiorespiratory monitoring in the neonatal intensive care unit An examination of the pros and cons of the cardiopulmonary monitoring techniques used in the ... mechanical, including photocopying, microfilming, and recording, or by any information storage and retrieval system, without permission in writing from the publisher Current printing (last digit): 10 PRINTED...
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Tài liệu Parkinson’s Disease and Related Disorders docx
... dopamine neurons in the CBLG-DT mice is unknown Just as there is no lasting increase in the adult number of SN dopamine neurons in the CBLG-DT mice, there is no increase in nigral dopaminergic innervation ... cocaine and MAO inhibitors, and showed that only the latter affected (increased) the levels of brain DA (Holzer and Hornykiewicz, 1959) Marthe Vogt, in her 1954 NA study in the dog brain, inferred ... prominent tremor, there was a peak at Hz, exactly half of their other peak in the alpha band Other components were in the midline and ap- peared to be modulated by the expectation of pressing the...
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Tài liệu Diseases and Disorders of Finfish in Cage Culture doc
... groupers in Malaysia, although large-scale cage farming in marine waters really gained ground in the 1980s and in inland waters in the 1990s (Shariff and Nagaraj, 2000) Korea started growing a European ... 1962) Marine fish farming in cages traces its beginnings to the 1950s in Japan where fish farming research at the Fisheries Laboratory of the Kinki University led to the commercial culture of the ... dramatic decline in the natural fish stocks and the increase in fish consumption by the ever-increasing population For example, the worldwide consumption of fish between 1990 and 1997 increased...
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Tài liệu Intracellular Traffic and Neurodegenerative Disorders pptx
... altered APP processing Contributions by Beyreuther and Kins and by Haass further informed the discussion by providing new insights into the proteins with which APP interacts, including its family ... Both the Loa and Cra1 lines encode point mutations in the gene encoding the heavy chain of cytoplasmic dynein Neither the F580Y Loa mutation nor the Y1055C Cra1 mutation maps within the dynein ... Upon ligand binding, the receptor/ligand-complex starts being endocytosed by the ligand-expressing cell, inducing shedding of the receptor by ADAM proteases (Gordon et al 2007) On the Intramembrane...
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Tài liệu PEDIATRIC NASAL AND SINUS DISORDERS doc
... symptoms In vitro and in vivo data have demonstrated a time-limited, rhinovirus induced release of epithelial derived proinflammatory cytokines and an increase in bradykinin, chemokine, and sICAM-1 ... surface the rhinovirus penetrates the cell After intracellular invasion and replication, the infection spreads to the nasal mucosa and to the pharynx (20) Typical for rhinovirus infections are the ... immunoglobulin superfamily and a major ligand binding site for rhinoviruses (21) Approximately 90% of the rhinoviruses infect their host by binding to this receptor (22,23) Once bound to the epithelial...
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Tài liệu Diseases and Disorders AIDS doc
... virus to gain a stronger foothold in the body The concentration of HIV in the blood increases, and subsequently more T cells are infected and killed As the cycle continues, the infected individual ... blood for the presence of the virus The Origins of an Epidemic 23 AIDS-infected blood, the statistics were terrifying to the public In the final weeks before blood banks began using the HIV test ... to integrate its own viral genetic material to that of the host cell, it can trick the host into producing viral proteins during the normal life cycle of the cell, turning the host into a living...
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Tài liệu Diseases and Disorders Sexually Transmitted Diseases doc
... people from one side of the globe to the other in a matter of hours The fact that certain STDs can be spread by contaminated blood is another factor in their rising incidence, since medical blood ... distress in children born to infected mothers In addition, the STD itself may be transmitted, with the child exhibiting the same symptoms as the infected mother Among the most serious infections ... Diseases the vagina or penis; the appearance of blisters or sores on the genitals; and pain, itching, or burning sensations during urination or sexual intercourse may arise within days of acquiring...
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Tài liệu Diseases and Disorders: Autism doc
... differences in the way the brain is wired These changes in the way the brain develops and works could be innate, or inborn However, some scientists believe the environment may be involved, too They ... pruning in autism might therefore lead to an increase in brain size and be associated with poor functioning of certain neural circuits [the wiring].”23 The wiring that lets the two halves of the ... visual thinking and imagination and coordinating input from the senses The temporal lobes are underneath the frontal lobes They are associated with hearing and memory Deep within the temporal lobes...
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Tài liệu MENTAL DISORDERS - THEORETICAL AND EMPIRICAL PERSPECTIVES docx
... concerns and understanding of what maintains the problem The patient is then encouraged to identify realistic goals regarding the problem and then start working on steps to solve the problem Skills in ... factors that maintain the desire to suicide, using thoughts records and/ or chain analyses Next, the therapist assists the patient in challenging the distortions and misconceptions, including core beliefs, ... Psychological/Physical Pain: Shneidman was among the first to stress the importance of the experience of pain in contributing to suicidal thinking and behaviors He referred to the pain of the suicidal patient...
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Tài liệu DISEASES AND DISORDERS A Nursing Therapeutics Manual THIRD EDITION pdf
... Incontinence, functional Urinary Incontinence, reflex Urinary Incontinence, risk for urge Urinary Incontinence, stress Urinary Incontinence, total Urinary Incontinence, urge Urinary Retention [acute/chronic] ... bruising of the flank area, may indicate retroperitoneal bleeding Inspect the perineum for accompanying urinary tract injuries that may lead to bleeding from the urinary meatus, vagina, and rectum ... Abdominal Trauma Abdominal trauma can be blunt or penetrating Blunt injuries occur when there is no break in the skin; they often occur as multiple injuries In blunt injuries, the spleen and liver...
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