roles in the regeneration of appendages bmp signaling and the activity of the hea
Báo cáo khoa học: FLIP and MAPK play crucial roles in the MLN51-mediated hyperproliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis pdf
Ngày tải lên :
23/03/2014, 07:20
... GM-CSF is involved in the proliferation of primary RA FLSs [7] In the present study, we investigated cell proliferation and MLN51 expression using an RA FLS cell line, MH7A, in the presence of GM-CSF ... upregulated in the FLSs of RA patients, and is enhanced days after GM-CSF treatment [7] In the present experiments, we assessed the dose and time kinetics of the effects of GM-CSF on MLN51 expression in ... localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells...
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The chemical components of detergents and their roles in the washing process
Ngày tải lên :
11/07/2014, 16:10
... fabrics and on the washing machine’s heating elements - stabilise alkalinity at the correct level throughout the washing process thus giving good soil removal and enabling the other components of the ... necessarily involves the inclusion of a number of complex, new chemicals and a complete restructuring on the detergent's formula, often with significant increase in other existing ingredients For each of ... break up large particles of dirt into smaller ones, which can be washed out, and they help prevent fine dirt particles from combining and thus keep them in suspension in the wash water Phosphates...
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Báo cáo y học: "Bench-to-bedside review: Functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis" ppsx
Ngày tải lên :
12/08/2014, 19:21
... walls off the injured site and contains the inevitable microbial contamination that occurs following a breach in the integument of this marine animal The basic elements of clotting and inflammation ... terminus of peptides and proteins In the case of fibrin, removal of carboxyl-terminal lysine residues renders the fibrin less sensitive to lysis by decreasing the ability of plasminogen and tissue-type ... [7,15] Any injury to the exoskeleton of the crab immediately jeopardizes the integrity of the internal milieu of the organism Not only is there a real threat of loss of internal contents of the crab...
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CHARACTERISATION OF GLUTAMYL TRANSPEPTIDASE AND ELUCIDATING ITS ROLES IN THE PATHOGENESIS OF HELICOBACTER PYLORI
Ngày tải lên :
09/09/2015, 17:58
... hypothesis Interestingly, nuclear localization of GGT coincided with a decrease in the levels of glutathione in the nucleus, indicative of a role of GGT in causing redox imbalance in host cells ... Cloning of ggt gene (full length and individual large and small subunits) from H pylori and expressing the recombinant proteins in E coli Raising and characterizing specific polyclonal and ... reduced ability to maintain long-term colonization in the gastric mucosa of the mice compared to the wild type strain, indicating the importance of catalase in the chronic persistence of H pylori (Harris...
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The integrator subunits function in hematopoiesis by modulating SMAD BMP signaling
Ngày tải lên :
14/09/2015, 14:06
... 1.4) The L45 loop within the type I receptor kinase domain and the L3 loop in the MH2 domains of R-Smads determine the specificity of intracellular signaling induced by TGFβs BMP- Smads, Smad1, and ... processing of U1 and U2 snRNAs (Uguen and Murphy, 2003) Therefore, they examined the promoter and coding region of U1 and U2 genes for the presence of the Integrator complex and RNAPII using ChIP The ... BMP function during vertebrate development as well Here, I am interested in studying the function of Integrator subunits, especially Ints5, and in elucidating the link between Ints5 and BMP signaling...
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Shooting the Sacred Cows of Money Putting a bullet in the head of bad financial advice
Ngày tải lên :
08/02/2014, 18:12
... thousands of people across the globe each year He is the author of the Rich Dad Advisor books The ABCs of Real Estate Investing, The Advanced Guide to Real Estate Investing, and The ABCs of Property ... Dad events on the topic of corporate formation and asset protection He is the author of the Rich Dad Advisor books The ABCs of Writing Winning Business Plans, The ABCs of Getting Out of Debt, Own ... author of the Rich Dad Advisor book, Guide to Investing in Gold and Silver Find out more at www.goldsilver.com Kathy Heasley Kathy is the founder and principal of Heasley & Partners, Inc., a branding...
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Tài liệu Improving health, connecting people: the role of ICTs in the health sector of developing countries ppt
Ngày tải lên :
14/02/2014, 09:20
... settings The complexity of choices of technologies and the complexity of needs and demands of health systems suggests that the gradual introduction, testing and refining of new technologies, in those ... reminding them about their medication The messages can be sent in one of three languages and in a range of styles to ensure they not become boring Of the 138 patients involved in the pilot, there ... beneficiaries, intermediaries and other stakeholders who are involved in the effective use of ICTs in the health sector Section explores potential and actual use of ICTs in the health sector It examines the...
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Tài liệu IN THE HEART OF AFRICA pptx
Ngày tải lên :
15/02/2014, 09:20
... pushed into the desert, farther and farther from the lost track where the pilot lay in his blood; and still the mocking spirits of the desert, the afreets of the mirage, led them on, and the hike ... ago The conversation of the Arabs is in the exact style of the Old Testament The name of God is coupled with every trifling incident in life, and they believe in the continual action of divine ... creation of a river was but the shadow of the great cause The rains were pouring in Abyssinia! THESE WERE SOURCES OF THE NILE! The journey along the margin of the Atbara was similar to the route...
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Tài liệu Báo cáo khoa học: What MAN1 does to the Smads TGFb/BMP signaling and the nuclear envelope Luiza Bengtsson pdf
Ngày tải lên :
19/02/2014, 02:20
... domain) binds prelamin A and B1 [8] in vitro, while the LEM domain alone is sufficient to bind BAF (Fig 1; [8]) Prelamin A and BAF are also binding partners of emerin [39] Interestingly, the N-terminus ... Smad binding suggesting that the RR-motif in MAN1 is a protein–protein interaction domain [13–17] Several independent experiments suggest that the antagonizing activity of MAN1 in TGFb ⁄ BMP signaling ... that of the inhibitory Smad Smad inhibits TGFb ⁄ BMP signaling not only by binding the respective type I receptors and interfering with phosphorylation of Smads, but also by binding R-Smads and...
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TRENDS IN THE HEALTH OF THE ELDERLY ppt
Ngày tải lên :
14/03/2014, 20:20
... all segments of the population Improvements in the health of persons in their 60s can be linked to eventual deterioration in the health of those in their 80s (5) This understanding of the complex ... trends in healthy life, which is a combination of mortality and morbidity dimensions BACKGROUND Theoretical Underpinnings of the Study of Trends in Health Theoretical development in the area of health ... developments in understanding the dimensions of health and the process of health change for an aging population Recent trends in each dimension of health are then reviewed, ending with a discussion of...
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The Effectiveness of Educational Intervention in the Health Promotion in Elderly people ppt
Ngày tải lên :
14/03/2014, 20:20
... diploma and their motivation and interest in participatory activities After interviewing candidates, 20 of them (male and female) were selected During a four-day training workshop, necessary instruction ... was meaningful Having a meaningful life and a feeling of happiness in all age groups has increased after the interventions (P= 0.00) In women aged 70 and older, Not being worried about the future, ... educational pamphlets to the elderly: In the initial phase of the study, educational materials were designed and prepared in order to support the volunteers During the initial phase of the home visits,...
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in the heat of the night
Ngày tải lên :
21/03/2014, 22:04
... part of the day, night time In the end, the fact of the matter was that the police didn't have him there by the law, he wasn't made clear of that in the beginning of the interview One thing that ... Journal: In The Heat Of The Night Vocabulary Word: Outskirt (noun) - The outer part of a town, far from the center of the town.Vocabulary Sentence: The house was located in the lonley outskirts of the ... put in the slammer for the murder of the man The murder was not done by Sam, as pointed out by Virgil The reason they thought that the officer did the crime was that he had installed the rest of...
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Alterations of matrix metalloproteinases in the healthy elderly with increased risk of prodromal Alzheimer’s disease pot
Ngày tải lên :
22/03/2014, 14:20
... These findings together point to the need to increase our understanding of the role of MMPs in AD and their relation to other AD-related markers in vivo Investigation of markers in cerebrospinal ... are in ng/l for Ab42, T-tau and P-tau and in ng/ml for the MMPs and TIMP-1 The findings of this study are in alignment with the elevated expression of MMP-3 and MMP-9 that have been observed in ... within each group and to define ‘individuals within the control group with increased risk for future AD’ The group difference in the CSF analysis method should therefore not influence the findings...
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Cognitive effects of acute tryptophan depletion in the healthy elderly potx
Ngày tải lên :
28/03/2014, 19:21
... Depletion minus placebo score great as that seen in the males receiving the lower dose drink In SMTS, the reduction in the females receiving the higher dose was not as great as the increase in the females ... those in studies in the young, thereby increasing the variance and making statistical significance less likely The absence of an interaction between age and ATD in this analysis may be explained ... 6.9 g, L-threonine 6.5 g, L-tyrosine 6.9 g and L-valine 8.9 g The composition of the smaller drinks was 80% (80 g) and 50% (50 g) of the larger drink The 100 g (80 g for females) drink will be referred...
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Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica ppt
Ngày tải lên :
28/03/2014, 20:20
... memorize the position of the illuminated windows In 36 subsequent presentations of the house, one of the windows was illuminated and the participant decided whether or not this matched one of the ... target digit was randomly selected and constantly displayed to the right of the monitor screen A series of digits was presented in the centre of the screen at the rate of 80 min−1 and the participant ... and quality of life and then they were assessed cognitive performance and mood after the single administration, and months of treatment whereas the quality of life was assessed after months of...
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Báo cáo khoa học: Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis pdf
Ngày tải lên :
28/03/2014, 23:20
... initiating the release of cytochrome c from mitochondria into the cytosol and increasing the activities of caspase and caspase 7, resulting in apoptosis of mouse RAW264.7 macrophages [30] Other ... protein, and was the first human protein shown to be indispensable for autophagy [44] The interaction between Beclin and its binding partners regulates the initial steps of autophagy Beclin also ... current opinions on how Bcl-2 and Bcl-xL are involved in the molecular events The crosstalk between the autophagy and apoptosis may redefine the roles of Bcl-2 and Bcl-xL in oncogenesis and tumor...
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The French in the Heart of America doc
Ngày tải lên :
31/03/2014, 13:20
... by the "overwhelming, unbending grandeur of the wonderful spirit ruling the flow of the sands, the lumping of the banks, the unceasing shifting of the channel and the send of the mighty flood." ... Missouri, the Ohio, and reached the mouth of the Arkansas, when thinking themselves near the gulf and fearing that they might fall into the hands of the Spaniards if they ventured too near the sea, and ... unable in 1682 to determine its longitude; the landing on the shores of Texas, far beyond the mouth of the Mississippi; the loss of one of the vessels to the Spanish, the wreck of two others, and the...
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univ of minnesota pr mathematical models in the health sciences a computer aided approach nov 1979
Ngày tải lên :
11/06/2014, 16:42
... to vary the content and even the emphasis of the course to meet the perceived needs of the class as well as to include some of the current interests of the instructors In addition to the formal ... physics, and biomedical engineering Many of the topics discussed in the following chapters are included in courses in these disciplines In addition models have been used in many other health-related ... arbitrary The importance of inverse solutions and model conformations is stressed and the goals of mathematical modeling in the health sciences are explored in this overview The remainder of the text...
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báo cáo sinh học:" Employment and sociodemographic characteristics: a study of increasing precarity in the health districts of Belo Horizonte, Brazil" pdf
Ngày tải lên :
18/06/2014, 17:20
... and the changes in the health districts (HDs) of the Municipal Health Secretariat of the City of Belo Horizonte (MHS-BH), concentrating on an investigation into the incorporation of workers and ... workers and non-permanent workers in the HDs; (2) to examine the profile of the permanent workers and non-permanent workers in the HDs as regards the composition and distribution of the following ... contained three correction factors: alteration of the reference date, by centring the index on the first day of the month; alteration of the value for July 1994 because of the change in the unit of...
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