... event
in determining the susceptibility to apoptosis through
maintaining the integrity ofthe mitochondria and
inhibiting activation ofthe caspase cascade [37]. High
expression levels of antiapoptotic ... expression of c-Fos and c-Jun, via the MAP
kinase signaling pathway.
TAM67 retains the DNA binding and leucine-zipper
region of c-Jun, but it lacks the transactivation domain
of c-Jun (amino acids ... h
after the start of treatment with EGF, indicating that
EGF regulated the level ofthe Bcl-X
L
protein at the
transcriptional level. Next we determined the effect of
ADR on the expression of Bcl-X
L
(Fig....
... Effects of active immunization of sheep against an amino
terminal peptide ofthe inhibin αC subunit on intrafollicular
levels of activin A, inhibin A and follistatin. Journal of Endocrinol-
ogy ... Regulation of granulosa cell-derived
insulin-like growth factor binding proteins (IGFBPs): role for
protein kinase-C inthe pre- and posttranslational modula-
tion of IGFBP-4 and IGFBP-5. Biology of ... assess the
equal transfer ofthe proteins from the gel to the mem-
brane. TBS-Tween was used to destain the membrane,
which was then blocked in 5% Marvel in TBS-Tween for
1–2 h. The blocking solution...
... education of occupational safety in
maintaining and preventing poison of pesticides.
2. Expand the model to all district and other tea growing areas, trial
research of model in other tea growing ...
Traders of pesticides sell a great deal of pesticides because the people
believe in only buying pesticides to their stores. Local medical staff
finishes the plan of taking care of and protecting the ... in Vietnam: The thesis
11-08 of Ministry of Agriculture and Rural Development in
combination with Ministry of Health and Ministry of Defence has
implemented from 1996 to 2000. In 2002, Bui...
... can therefore postulate
that, when the segment beyond W140 was removed, the
secondary structure ofthe protein disintegrated. Using
the peak at 222 nm ofthe wild-type protein as an index
of helical ... 3).
Summary
Trp140 located inthe C-terminal loop of SNase plays
an important rolein protein stability and conforma-
tional integrity. During protein unfolding ⁄ refolding,
the addition of 2.5 protons (both ... analysis of protein unfolding
The DSC curves ofthe wild-type protein and the
mutants K133A, E142O, W140A and W140O are
shown in Fig. 3, with their thermodynamic parameters
summarized in Table 1. The...
... sites of pADH10. The
resulting plasmid, named pDHEB, contains the gene
encoding DCH lacking the C-terminal region, in which
Asp and His residues involved inthe catalytic triad are
contained. The ... ligating the isolated DNA inthe range of 5.7 kb
into pBluescript SK II (+), and then transforming the
ligation mixture into E. coli JM109. Colony hybridization
led to the identification of a single ... to the ability of dch to catalyse the peroxidation of
organic acids, which could be an intermediary reaction of
halogenation, and it is assumed that theroleof DCH in vivo
is the degradation of...
... We investigate whether related variety among high-tech sectors has affected
regional growthin Finland inthe period 1993-2006, during which the Finnish economy
changed into a high-tech economy. ... Hermans R (2004) Nokia: A Giant inthe Finnish innovation system. In:
Schienstock C (ed) Embracing the Knowledge Economy. The Dynamic Transformation ofthe
Finnish Innovation System. Edward Elgar, ... during which the
economy of Finland changed into a high-tech economy, with an increasing variety within the
high-tech sector. Inspired by the approach taken by Frenken et al. (2007), we investigate...
... 3). Intensity ofthe green band is greater than that ofthe blue band. As increasing the
concentration of Cu, the intensity ofthe blue band decreases while the intensity ofthe green band
increases ... increases, the intensity ofthe blue band
decreases while the intensity ofthe yellow-orange band increases gradually and reaches to the
maximum at x
Mn
= 8.10
-3
mol%. However, the position of this ...
positions of Zn
2+
ions or vacancies of Zn in ZnS crystal. With increasing of concentration of Cu
beyond 3.5.10
-4
mol%, the intensity ofthe green band decreases. Because at high concentration of...
... about theroleof these factors in vivo and their role in
furunculosis. The A-layer is believed t o play a crucial role
inthe bacterial protection against c omplement-mediated
killing in vitro ... detected inthe bacterial inoculum TSB culture used to
prepare thein vivo growth chambers. Direct CE-ES-MS
analysis ofthein vivo bacterial cells cultured within the
semipermeable growth chambers ... sample of A. salmonicida (data not shown).
The proposed structure of CPS and O-chain polysaccharide
of A. salmonicida strain 80204-1 is depicted in Fig. 5.
The biological significance of these findings...
... Reproduced with permission ofthe copyright owner. Further reproduction prohibited without permission.
Reproduced with permission ofthe copyright owner. Further reproduction prohibited without ... permission.
Reproduced with permission ofthe copyright owner. Further reproduction prohibited without permission.
Reproduced with permission ofthe copyright owner. Further reproduction prohibited without ... permission.
Reproduced with permission ofthe copyright owner. Further reproduction prohibited without permission.
Reproduced with permission ofthe copyright owner. Further reproduction prohibited without...
...
taxol increased the expression ofthe anti-apoptotic protein
Bcl-xL, and increased the mobilization of p65 subunit
molecules into the DC nucleus. Furthermore, we found that
the inhibition of ...
enhances DC viability. These findings provide a basic
rationale for the use of taxol in DC immunotherapy and
insights into the development of combinational DC
therapies with other anticancer drugs ... not increased (Fig.
3). The protein expression levels were calculated in
comparison to the level of β-actin (internal control). The
results suggest that taxol enhances DC viability via the
increase...
... modulation of other known genes that involved in
TG biosynthesis as ASP and HSL [9,13]. Inthe study of De
Barros et al. [9], the chronic lactacystin treatment of
preadipocytes in an adipogenic ... plasmin and thrombin, 2)
EDTA- metalloproteases, 3) leupeptin hemisulfate salt as
plasmin and cathepsin, 4) cystein proteases as leucin
aminopeptidase and alanyl aminopeptidase.
The use of retroviral ... high dose (450 ng/mL) together with
insulin, there was an additive increase in lipids accumulation
was seen (Fig. 4). When the cells were incubated in
presence of insulin and PI, TG accumulation...
... to the consumption of seed
reserves. Thus, the kinetic of changes in dry weight and in nitrogen
content of both the cotyledons and the growing plant, was established
prior to the analysis ofthe ... emergence resulted in a significant reduction in seedling
growth. Shading had a minor effect during this period. However, the influence of cotyledons on seedling growth declines soon. Their artificial
suppression ... to the
respective controls. Interestingly, cotyledon removal reduced
growth to a larger extent inthe light than under shade.
The time course ofthe impact of cotyledon severing after
increasing...
... mediate
ubiquitination of various target proteins, and the intracellular
domain ofthe Notch receptor (involved inthe maintenance of
cells in an undifferentiated state), both of which notably
contain ankyrin repeat ... in RA, then this might lead to activation of the
NF-κB signalling cascade. However, there is hardly any
evidence inthe current literature of expression ofthe HIF
regulating PHD enzymes inthe ... Inthe present review
we focus on current knowledge ofthe regulation ofthe HIF
pathway, and then consider the potential roleof hypoxia in
the pathogenesis of RA.
Why is hypoxia a feature of...