... calcium-independent
phospholipase A
2
participates in ER stress-induced
INS-1 insulinoma cell apoptosis by promoting cera-
mide generation via hydrolysis of sphingomyelins by
neutral sphingomyelinase. ... leading to the accumulation
of sphingomyelin [27]. Because one of the pathways
for ceramide recycling is the sphingomyelin pathway, it
is conceivable that in addition to the accumulation of
Fig. ... data
suggesting that some of the genes involved in the
genetics of Lewy body disease, have in common the
fact that they impinge on ceramide metabolism. One
shortfall of the present theory is the lack of...
...
ethanol-induced mucosal injury in the upper
gastrointestinal tract leading to increase in the
permeability of the gut mucosa to endotoxins [43, 44].
These factors are involved in ethanol-induced ... . Interestingly, HMGN3 has been
found to be associated with resistance against
anticancer drugs including vinblastine, topotecan,
paclitaxel and doxorubincin in human hepatocellular
carcinoma ... signaling. This finding corroborates the
interaction observed between various intracellular
signaling pathways and apoptosis induced by 1mM
concentration of ethanol in HepG2 cells [19].
Int....
... 6—
Making Your E-mail Go Further and Do More
E-mail is playing an increasingly important roleinbusiness communication, with tens of millions of pieces of mail being transmitted daily. In 1998, ...
Implementing Your Communications Strategy
8
Company-Level BusinessCommunication Trends
9
Developing Effective BusinessCommunication within Teams
10
Developing Effective BusinessCommunication ... Forward MBA inBusiness Communication& quot;
Supply-Chain Linkages in Nonmanufacturing Environments
Supply-chain-like linkage problems are also inherent in service organizations. Nonprofit and government...
... situations (in
movieland) wiped out the lives of innocents, or at least associated with it in my sometimes
quaint way of looking at thing
It consciously came back into my mind again, when Schindler's ... many fish eat other things instead of fish, thus making the chain
of feeding way more intricate. But the concept remains: there is always some entity capable of putting
things right. And believe ... you into and out of War. Enjoying the
multitude of songs like for instance 'Princes of the
Universe' by Queen, I'm now going to explain further
how this all links together in...
... in exploring on-line banking business as well as in promoting
non-bank financial institutions. Efforts should be made in upgrading financial
operations and financial services, and in conducting ... China Statistics Yearbook, China Financial Yearbook and People’s Bank of China
Statistics Quarterly bulletin.
B. Development of direct financing and indirect financing markets
providing financing ... The roleof FDI in institution building
Over the past 20 years, foreign financial institutions, mainly foreign banks have
played an important rolein the opening up of Chinese financial industry....
... much of their time ducking,
dodging, avoiding, pretending, lying, hiding their emotions
and feelings, using smokescreens or mirrors and waving to
imaginary friends in the crowd. But we instinctively ... to
28
The Definitive Book ofBody Language
The key to reading bodylanguage is being able to understand
a person's emotional condition while listening to what they are
saying and noting the circumstances ... fake bodylanguage for a short period of time and even-
tually the body will show contradictory signals that are
independent of conscious actions. Many politicians are
experts in faking body language...
... shown that interactions between
KCs and endotoxin comprise the initiating event lead-
ing to hepatotoxicity in liver injury, including endotox-
emia and ischemia ⁄ reperfusion injury [14]. In our
studies, ... signaling is independent of
Toll-interleukin 1 receptor domain-containing adaptor
protein. Drug Metab Dispos 36, 95–101.
10 Ghose R, Guo T & Haque N (2009) Regulation of gene
expression of hepatic ... stimulation of these receptors activates in amma-
tory responses characterized by the release of a wide
range of proinflammatory cytokines, including IL-6
Sham GdCl
3
CLP GdCl
3
+ CLP
HMGB1
iNOS
β-actin
Fig....
... renewed interest in examining the indications for BCG vaccination in the
United States included consideration of the wide range of vaccine efficacies deter-
mined by clinical trials and estimated in ... should continue to be included in ongoing testing programs if their skin-test
results are <5 mm induration. Those vaccinees who have positive tuberculin skin-test
reactions (≥5 mm of induration) ... preventing pulmonary TB in adoles-
cents and adults. These studies also were not useful in determining a) the efficacy of
BCG vaccine in HCWs or b) the effects on efficacy of the vaccine strain administered
6...
... would involve
the following determinations: in terms of
producing information about possible invest-
ments and allocating capital, the financial
(a) developing and analyzing measures of the ... REPORT 2013 1
GLOBAL FINANCIAL DEVELOPMENT REPORT 2013
Rethinking the
Role of the State in Finance
Washington, D.C.
GLOBAL FINANCIAL DEVELOPMENT REPORT 2013 BENCHMARKING FINANCIAL SYSTEMS AROUND ... respondents seeing potential
benefits in more stringent supervision of new finan-
cial instruments in light of the crisis. A majority
also see a scope for a more active roleof the state
in promoting technological...
... larger
banks in making small business loans. Loan officers at small banks can
take into account a wide variety of factors in reviewing applications for
small business loans, including the character of ... 1998. “Small Business Lending and the
Changing Structure of the Banking Industry,” Journal of Banking and
Finance, August.
Sullivan, Richard J. 2000. “How Has the Adoption of Internet Banking Affected
Performance ... banks in lending to small businesses. According to one
recent estimate, commercial banks of all sizes supplied 37 percent of
small business debt in 1993, where small businesses are defined as...
... dis-
charge can contain a wide range of contaminants and originate
from a myriad of sources. Some of the biggest generators of
toxic industrial waste include mining, pulp mills, tanneries,
sugar ... from
mining operations can contain silt and rock particles and sur-
factants. Depending on the type of ore deposit being mined,
tailings can also contain heavy metals like copper, lead, zinc, ... examples of persistent environmental damage caused by
the discharge of toxic mine waste. In Papua New Guinea for ex-
ample, companies discharge millions of tons of contaminated
mine waste into...
... facing business
Regaining the Public Trust
Effective company management in the
context of today’s investor expectations
Ensuring the integrity of financial
reporting
Ethical role- modeling of senior
management
Fairness ... on trust in my
company and on public trust in business?
6. What role can my sector play in positively impacting key areas
of trust? What role can business associations play in changing
public ... challenge of public trust in
business.
The Institute and the Arthur W. Page Society are
launching the Project on Public Trust in Business, an
ongoing effort to engage other leading organizations
in...
... or without hematoxylin staining.
In hypoxia experiments, 3T3-L1 cells were maintained in
a hypoxia chamber (Invivo 400; Ruskinn Inc., Cincinnati,
OH, USA) constantly maintained at 1% O
2
. Culture
medium ... cultured in DMEM containing 10% fetal bovine
serum. OP9 cells were grown in aMEM containing 20%
fetal bovine serum. C2C12 cells were maintained in DMEM
containing 10% fetal bovine serum.
Adipogenic ... regulator of energy metabolism
in the fat bodyof fruit flies [3]. In vertebrates, miR-
375 and miR-376, both of which are abundantly
expressed in pancreatic b-cells, are involved in the con-
trol of insulin...
... rolein skin wound
healing. After a skin injury, PPARb expression is rap-
idly elevated in the epidermis at the wound edges; dele-
tion of a single PPARb allele results in delayed wound
healing ... cultured
human keratinocytes [14].
In this study, we examined the interaction between
CerK and PPARb, and its rolein regulating keratino-
cyte survival. We report that in a mouse keratinocyte
cell line upregulation ... important rolein keratinocyte sur-
vival during skin wound healing, and PPARb expres-
sion is elevated at injury sites [10,15]. We investigated
whether skin barrier disruption by tape-stripping
would...
... detected at
the dimer interface of the models or in the surroundings of
the hinge loop residues. Likewise, the models of nonex-
changing and exchanging HHP-RNase were prepared start-
ing from 1Z7X. ... strong, neutralizing action of the cytosolic RNase
inhibitor (cRI), a 50-kDa protein containing 16 leu-
cine-rich repeat motifs [7,8]. In fact, onconase from
Rana pipiens eggs [9], and seminal RNase ... detected at the dimer
interface of the models or in the surroundings of the
mutated residues. The models of RNase A covalent dimers
in the exchanging conformation were prepared using the
7RSA structure...