role in rem sleep regulation
báo cáo khoa học: "Regulation of cell cycle transition and induction of apoptosis in HL-60 leukemia cells by lipoic acid: role in cancer prevention and therapy" ppt
... 24 h resulted in a 1.5 fold increase in total cytochrome c, while the total AIF levels remained unchanged (Fig 3C) As bcl-2 plays an integral role in the release of cytochrome c during cell death, ... growth inhibition assay Human HL-60 cells were obtained from American Tissue Culture Collection (Manassas, VA) and maintained in RPMI 1640 supplemented with penicillin, streptomycin and 10% heat inactivated ... nucleus and promoting the caspase-independent induction of apoptosis chrome c in the activation caspase-independent apoptosis, as involving the nucleus accumulation of cytochrome c instead of a more...
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báo cáo khoa học: " The transcription factor PHR1 plays a key role in the regulation of sulfate shoot-to-root flux upon phosphate starvation in Arabidopsis" potx
... by phosphite, indicating that phosphite interferes specifically with early events involved in Pi sensing and signaling, including responses typically associated with local Pi sensing or long-distance ... events involved in Pi sensing and signaling, including responses typically associated with local Pi sensing or long-distance signaling [47-50] While addition of phosphite attenuated the induction ... http://www.biomedcentral.com/1471-2229/11/19 of coordination and crosstalk must exist between pathways involved in Pi and sulfate transport and homeostasis in plants, important players acting in this coordination remain to be clearly...
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Báo cáo y học: "New role for Agrin in T cells and its potential importance in immune system regulation" ppsx
... splicing at the amino terminus produces either a type II transmembrane protein (TM-Agrin) or a secreted protein (SS-Agrin) [19,20] (Figure 1) SS-Agrin also contains a laminin-binding domain immediately ... domain FL: Follistatin-like domain NtA: amino-terminal agrin domain LE: Laminin d id LE L i i and epidermal growth f t lik d l th factor-like domain i EL LGL B/z S/T: Serine/Threonine rich domain ... Agrin has a role, at least in part, in maintaining synaptic structure in this tissue [23] In addition, Agrin is expressed at high levels in the brain microvasculature, where it could play a role...
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REGULATION OF CHOP TRANSLATION IN RESPONSE TO eIF2 PHOSPHORYLATION AND ITS ROLE IN CELL FATE
... heme-binding regions in HRI: an N-terminal domain of HRI and in an insert region in the protein kinase domain of HRI (63) Heme, in the presence of iron, binds to α and β globin chains in ratio ... cytoplasmic splicing of mRNA encoding the Xbox binding protein1 (XBP1) in mammals and homologue of the mammalian activating transcription factor/cAMP-response element (CRE)-binding protein (HAC1) in yeast ... mouse, result from insulin gene mutations that affect insulin folding process (144) As a consequence, the unfolded insulin forms aggregates in a dominant fashion, rendering insulin non-functional (145,...
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Elucidation of the physiologic role of TRIP br2 in cell cycle regulation and cancer pathogenesis
... chromatin resulting in either gene activation or repression For instance, the appearance of histone acetyltransferases, including cAMP-responsive element binding (CREB) protein-binding protein (CBP), ... mammalian E2F proteins E2F1–6 contain one DNAbinding domain (DB) and one DP dimerization domain (DIM) Transactivation domains and sequences for binding to pocket proteins are present only in E2F1–5; ... 2000) CDK protein levels remain stable during the cell cycle, in sharp contrast to their activating proteins, the cyclins The oscillatory expression of most cyclin proteins during cell cycle...
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Role of p73 in regulation of cell death specific role in mitotic cell death and potential regulation of caspase 2s
... together during mitosis, thus allowing chromatids to separate during anaphase towards opposing poles In the cells, the spindle checkpoint is kept active through the binding of inhibitory proteins BubR1 ... to understand the role of p53 family during DNA damage response, not much is known about its role in maintaining genomic integrity through initiating mitotic catastrophe The main aim of this research ... 3.41: RT-PCR showing induction of p73β in Soas2 cells resulting in upregulation of bim mRNA levels 123 Fig 3.42: p73 bind to p73RE on bim intron 125 Fig 3.43: Cell cycle dependent binding of p73 to...
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Báo cáo y học: " Vgf is a novel biomarker associated with muscle weakness in amyotrophic lateral sclerosis (ALS), with a potential role in disease pathogenesis"
... tissue staining intensities influenced the measured values Average value density measurements from individual Vgf immunoreactive dorsal spinal cord neurons, reflecting immunostaining intensity, ... delimiting the cellular area of interest free hand, using predetermined criteria to define the region of interest The immune intensity of the cellular Vgf encompassing the L3-L5 regions of spinal ... C-terminal epitope of Vgf Unoccupied binding sites on the plates were blocked by incubation with casein Samples and standards were applied in duplicate and incubated overnight at 4°C Following...
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Hydrophytes may play an important role in sewage disinfection in constructed wetlands
... 12.6 mg·L-1, respectively In conclusion, P hydropiper may play an important role in sewage disinfection in CWs, but its living inhibiting pathogenic micro-organisms in the ecosystem need to be ... constructed wetland in Beijing, J of Communications in Nonlinear Science and Numerical Simulation., 13: 1986~1997 Lin Y F, Jing Sh R, Lee D Y, et al (2008) Nitrate removal from groundwater using constructed ... improving nitrogen removal in constructed wetlands—promoting coexistence of partial-nitrification and ANAMMOX, J of Ecological engineering., 31: 69~78 Hafner S D, Jewell W J (2006) Predicting nitrogen...
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The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis
... direct down regulation of cyclin protein levels or by inducing members of the INK4A and/or CIP/KIP family of cyclin dependent kinase inhibitors (CKI), resulting in the down -regulation of cyclin/Cdk ... Flemington et al 1993) However, expression of an E2F variant containing the DNA binding motif but not the pRb-binding or transactivation domain or introduction of a competitor plasmid containing ... while the pocket-domain and the C-domain are involved in binding E2F proteins Mdm2 (as well as c-Abl) binds to the C-domain All pocket proteins are subject to phosphorylation (indicated with “P”)...
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Tài liệu Georgia Oral Health Prevention Program The School Nurse’s Role in Oral Health pdf
... health by serving as a significant source of information and participating in prevention programs such as providing dental health education, intervening in dental emergencies, and advocating the provision ... flossing of teeth and good brushing, prompt, professional dental care including replacement of ill fitting crowns and fillings, and halting the use of smokeless tobacco, and prevention of grinding ... early; rarely interferes with feeding or nursing Χ No treatment necessary unless tooth is extremely loose TOOTHBRUSHING AND FLOSSING Χ Χ Χ Χ Toothbrushing (at least minutes) helps to remove plaque...
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Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
... deletion of RasGEF; KIND1, KIND1 domain; KIND2, KIND2 domain (B) KIND2 domain anchors v-KIND to dendrites Flag-tagged v-KIND, DKIND1, DKIND2, DKIND1 + 2, DRasN, DGEF, KIND1 or KIND2 together with ... very-KIND-MAP2 interaction A 37–217 456–620 KIND1 KIND2 v-KIND ΔKIND1 ΔKIND2 ΔKIND1+2 ΔRasN ΔGEF KIND1 KIND2 ΔKIND1-Flag RasN ΔKIND2-Flag 1461–1734 1742 GEF ΔKIND1+2-Flag dendrite axon ΔGEF-Flag KIND1-Flag ... functional determinants of the protein–protein interaction between v-KIND and MAP2 (i.e the MAP2-binding core module in v-KIND and the v-KIND-binding core module in MAP2) across a range of amino acid...
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Tài liệu Báo cáo khoa học: NirF is a periplasmic protein that binds d1 heme as part of its essential role in d1 heme biogenesis pdf
... denitrifying conditions than Ps aeruginosa NirF also shares 34% sequence similarity with the beta-propeller domain of cd1, indicating a scaffolding role for an intermediate of heme d1 synthesis Roles ... and consumption in Paracoccus pantotrophus strains Starter cultures were grown aerobically in LB with shaking before inoculation of mineral salt medium containing 20 mM nitrate in a 1% v ⁄ v dilution ... similar to that in Asp141 of Met8P The idea of NirF being a dehydrogenase is appealing because of the presence of a putative nucleotide-binding motif in the N-terminal of the protein sequence and...
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Tài liệu SYSTEM ROLE IN ORACLE ppt
... thống, INSERT, DELETE, UPDATE bảng SYS.INCVID, SYS.INCFIL, SYS.INCEXP EXECUTE_CATALOG _ROLE SELECT_CATALOG _ROLE www.themegallery.com LOGO HS_ADMIN _ROLE www.themegallery.com LOGO HS_ADMIN _ROLE ... www.themegallery.com LOGO Contents EJBCLIENT EXECUTE_CATALOG _ROLE EXP/IMP_FULL_DATABASE HS_ADMIN _ROLE GATHER_SYSTEM_STATISTICS GLOBAL_AQ_USER _ROLE www.themegallery.com LOGO EJBCLIENT www.themegallery.com ... đồng (HS – Herterogeneous Service) www.themegallery.com LOGO HS_ADMIN _ROLE Được cấp cho SELECT_CATALOG _ROLE EXECUTE_CATALOG _ROLE Vì người dùng truy cập đến từ điển liệu chung truy cập vào...
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Tài liệu SYSTEM ROLE IN ORACLE DEMO pdf
... www.themegallery.com LOGO EXECUTE_CATALOG _ROLE connect test0/p123; exec DBMS_LOCK .sleep( 50); www.themegallery.com LOGO EXECUTE_CATALOG _ROLE connect test1/p123; exec DBMS_LOCK .sleep( 50); www.themegallery.com ... EXECUTE_CATALOG _ROLE Package: DBMS_LOCK Produres and functions: procedure allocate_unique(…); function request(…); function convert(…); function release(…); procedure sleep( seconds in number); ... www.themegallery.com LOGO EXP_FULL_DATABASE connect test0/p123; create table A( id varchar2(10) ); insert into A values ('abc'); connect test2/p123; create table B( id varchar2(10) ); www.themegallery.com...
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Tài liệu LIVESTOCK''''S ROLE IN CLIMATE CHANGE AND AIR POLLUTION ppt
... trapping it in the atmosphere The principal greenhouse gases involved in this process include carbon dioxide (CO2), methane (CH4) nitrous oxide (N2O) and chlorofluorocarbons Since the beginning ... al., 2005) Global warming is expected to result in changes in weather patterns, including an increase in global precipitation and changes in the severity or frequency of extreme events such as ... However, livestock’s role in deforestation is of proven importance in Latin America, the continent suffering the largest net loss of forests and resulting carbon fluxes In Chapter Latin America was...
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Tài liệu The UN’s Role in Nation-Building - From the Congo to Iraq pptx
... birth Within days of the Congo’s independence its army mutinied, the remaining white administrators fled, the administration and the economy collapsed, Belgian paratroops invaded, and the mineral-rich ... end in Somalia and were further diminished by events in the former Yugoslavia In both instances, UN-led peacekeeping forces were inserted into societies where there was no peace to keep In both ... the view that nation-building can be an effective means of terminating conflicts, insuring against their reoccurrence, and promoting democracy The sharp overall decline in deaths from armed conflict...
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Tài liệu Báo cáo khoa học: Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen pdf
... PDZ proteins: Mint-3, AMPA binding protein and glutamate receptor interacting protein (GRIP) It would therefore be interesting to determine whether this motif is also involved in the interaction ... Roghi et al Role of GRASP55 in MT1-MMP activation l l l l l l l l l l l l l MINT-7897617, MINT-7897659, MINT-7897681, MINT-7897702, MINT-7897725, MINT7898032, MINT-7898011, MINT-7897907, MINT-7897884: ... UK) were maintained in DMEM containing 10% (v/v) fetal bovine serum (Hyclone Laboratories Inc., UT, USA), mm l-glutamine, 100 UÆmL)1 penicillin and 100 lgÆmL)1 streptomycin at 37 °C in 5% CO2...
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Tài liệu Báo cáo khoa học: Mixed lineage leukemia histone methylases play critical roles in estrogen-mediated regulation of HOXC13 docx
... their binding profiles in a time-dependent manner in ERE1 and ERE2 (Fig 5B) In agreement with the above findings, binding of ERa and ERb was increased in both ERE1 and ERE2 in the presence of E2 Interestingly, ... However, in the case of ERb, some constitutive binding was observed in ERE2 even in the absence of E2, and this binding was increased in the presence of E2 (Fig 5A,B; compare h and 6–8 h time points) ... presence of E2 Binding of ERa and ERb was increased in both ERE1 and ERE2 of the HOXC13 promoter (Fig 5A, lanes 1–4) The levels of E2-induced binding of ERa and ERb were higher in ERE2 than in ERE1 ERE3...
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Tài liệu Báo cáo khoa học: The role in the substrate specificity and catalysis of residues forming the substrate aglycone-binding site of a b-glycosidase docx
... (dimboa-Glc) was included to facilitate the visualization of the active site (C) Aglycone-binding site of SbDhr1, including the substrate dhurrin (D) Aglycone-binding site of BglB, including the inhibitor ... aglycone-binding site (Fig 1) Hence, these residues are potentially involved in aglycone binding [13,17] In addition, other residues form a ‘layer’ that helps in the positioning of the residues that interact ... not affect the binding of the glycone within the Sfbgly active site This hypothesis was further investigated by determining the in uence on the glycone binding of the Sfbgly interactions with...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25