robust image registration based on learning prior appearance model
nanotechnology for cancer therapy, 2007, p.810
... discussion on nanotechnology characterization for cancer therapy, as well as guidance from the U.S Food and Drug Administration on approval of nanotechnology products Section focuses on polymeric conjugates ... Edmonton, Alberta, Canada Eun Seong Lee Amorepacific Corporation/R&D Center Giheung-gu Yongin-si Gyeonggi-do South Korea Helen Lee Department of Pharmaceutical Sciences University of Toronto Toronto, ... their intracellular accumulation shortens the spin relaxation process of nearby protons detectable by MRI On magnetic resonance images, those node regions accumulating iron oxide appear dark relative...
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báo cáo hóa học: " In vitro and in vivo pre-clinical analysis of a F(ab’)2 fragment of panitumumab for molecular imaging and therapy of HER1-positive cancers" pot
... determination of a bifunctional DTPA ligand in DTPA monoclonal-antibody conjugates Bioconjugate Chem 1992, 3:342-5 32 Garmestani K, Milenic DE, Plascjak PS, Brechbiel MW: A new and convenient ... subcutaneous (s.c.) injections in the flank with × 106 cells in 0.2 mL of media containing 20% Matrigel ™(Becton Dickinson, Bedford, MA, USA) or intraperitoneal (i.p.) injections of × 10 cells in mL ... radioactivity in the containing volume, smaller ROIs were consistently drawn to enclose the organ Upon completion of the imaging session, the mice were euthanized and biodistribution studies were performed...
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Surface functionalization of superparamagnetic iron oxide nanoparticles for potential cell targeting, imaging, and cancer therapy applications
... iron concentration of 0.5 mM and (b) as a function of incubated iron concentration for an incubation period of h Inset is the image of macrophages incubated with PLMA-2-SPIONs at an iron concentration ... gadolinium -based T1 contrast agents, since the effect of SPIONs on proton relaxation rates is 10-fold stronger than that of gadolinium Thus, SPIONs can potentially be detected at a much lower concentration ... PLMA-2SPIONs, and (b) with PLMA-2-SPIONs at an iron concentration of 0.5 mM, after staining with Prussian Blue. Figure 3-9 Uptake of PLMA-2-SPIONs by macrophages (a) as a function of incubation...
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Molecular Imaging: An Essential Tool in Preclinical Research, Diagnostic Imaging, and Therapy potx
... function Examples of reconstituted activities include activation of transcription, repression of transcription, activation of signal transduction pathways, and reconstitution of a disrupted enzymatic ... Protein-fragment complementation (PFC) assays depend on division of a monomeric reporter enzyme into two separate inactive components that can reconstitute function upon association When these reporter ... of antisense and aptamer oligonucleotides will be considered here 1.5.1 Antisense Oligonucleotides Based on the formation of a Watson-Crick hybrid between an oligonucleotide and an RNA, the antisense...
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The use of gold nanostructures in the imaging and therapy of cancer
... illumination To acquire the images of both suspensions under the same conditions, the concentration of the polymeric beads (in particles/ml) was increased 6-fold relative to the concentration of ... the concentration of gold nanoshells localized in tumor and the injected gold nanoshells concentration (-■-) The tumor concentration of gold nanoshells expressed as a fractional concentration of ... gaining attention in the early detection of diseased conditions These non-fluorescent imaging techniques form their image based on other types of optical changes such as optical absorption or scattering...
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Báo cáo hóa học: " Both FA- and mPEG-conjugated chitosan nanoparticles for targeted cellular uptake and enhanced tumor tissue distribution" docx
... http://www.nanoscalereslett.com/content/6/1/563 Page of 11 Figure Confocal images Confocal images of HeLa cells after incubated 24 h with different kinds of modified NPs at the same concentration 0.1 mg/ml; the ... discussion The preparation and characteristics of differential kinds of NPs Figure shows the process of the preparation and modification of NPs, and the scanning electron microscope image of ... loading content of MMC on mPEG-FA-NPs were 29.2 ± 3.2% and 9.1 ± 1.6%, respectively The drug-loading content was influenced by the functional group because part of the amino group on the backbone...
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Báo cáo y học: "Rasburicase represents a new tool for hyperuricemia in tumor lysis syndrome and in gout Lisa Cammalleri and Mariano Malaguarnera"
... allopurinol, after the discontinuation for skin rashes [50] As explained, allopurinol action is delayed, because it acts on uric acid synthesis In an oncologic emergency condition, such as TLS, we need ... its concentration increases after protracted administration [56,57] So owing to its activity, its long elimination half- life and its urine excretion, it requires a dosage reduction, in case of ... [19] Tumor lysis syndrome (TLS) is a spontaneous condition (present in haematological malignancies and other conditions) or, more frequently, occurring in consequence of chemotherapy, radiotherapy...
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Báo cáo khoa học: Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis pptx
... with uronic acid Units of N-acetylglucosamine and glucuronic ⁄ iduronic acid form heparan sulfate (HS) The polysaccharide chains are modified at various positions by sulfation, epimerization and ... months (25 years) following diagnosis, whereas none of patients stained strongly for heparanase survived at 300 months [45] Somewhat surprising, heparanase upregulation in head and neck and tongue ... C-domain is indeed a valid functional domain responsible for Akt phosphorylation The cellular consequences of C-domain overexpression were best revealed by monitoring tumor xenograft development...
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adobe digital imaging how-tos 100 essential techniques for photoshop cs5, lightroom 3, and camera raw 6
... that the contents of the folder are not based on the physical location of the files, but rather on the characteristics of the files For this reason, smart collections—Lightroom’s version of smart ... Lightroom to recognize the connection (continued on next page) #10: Tethered Capture 24 All you need to is click the Capture button in Lightroom or the shutter release button on your camera to take ... synchronize the magnification of two images without locking or linking their Zoom levels, right-click one of the images and choose Sync Focus in the context menu, or just click the Sync button,...
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patel, chellapa - sparse representations and compressive sensing for imaging and vision
... 3.2 Sample image reconstructions (a) 256 × 256 original image (b) Image reconstructed from only 2% of the measurements (c) Image reconstructed from only 10% of the measurements [149] One of the ... reconstruct using SPC The original dimension of the image is N = 256 × 256 The reconstructed images using total variation minimization from only 2% and 10% measurements are shown in the second ... tutorials on the applications of compressive sensing in the context of optical imaging as well as analog-toinformation conversion 3.1 Single Pixel Camera One of the first physical imagers that demonstrated...
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báo cáo hóa học:" Comparative study of 64Cu/NOTA-[D-Tyr6,beta-Ala11,Thi13,Nle14]BBN(6-14) monomer and dimers for prostate cancer PET imaging" potx
... dimeric BBN -based tracers in prostate cancer PET imaging Abbreviations The abbreviations for the common amino acids are in accordance with the recommendations of [40] Additional abbreviations: %ID/g, ... crude peptide NOTA, 1,4,7-triazacyclononane-1,4,7triacetic acid; Ki, inhibition constant Table Bio-distribution and tumor to non-target organ ratios for 64Cu/NOTA-monomer and 64Cu/NOTA-dimer Organ ... with longer tumor retention [26] Potential benefits of multimeric targeting peptides are accepted, but many questions concerning the mechanisms are still to be answered A few studies on BBN-based...
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Báo cáo y học: "Autologous chondrocyte implantation for cartilage repair: monitoring its success by magnetic resonance imaging and histology" ppt
... elongated and often more numerous Vascularisation and mineralisation were identified on H&E-stained sections, mineralisation being confirmed where necessary with von Kossa stain For comparison ... histochemical assessment can provide only limited information, as it is from a discrete location MRI, in contrast, can provide information on the whole area In addition, it is noninvasive and successive ... Richardson JB, Caterson B, Evans EH, Ashton BA, Roberts S: Repair of human articular cartilage after implantation of autologous chondrocytes J Bone Joint Surg Br 1999, 81:10641068 Harrison PE, Aston...
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Báo cáo khoa học: "Preoperative Y-90 microsphere selective internal radiation treatment for tumor downsizing and future liver remnant recruitment: a novel approach to improving the safety of major hepatic resections" docx
... a reasonable candidate for surgical resection based on her relatively long disease-free interval and the absence of any locoregional recurrence or detectable extrahepatic disease A decision was ... not for citation purposes) World Journal of Surgical Oncology 2009, 7:6 http://www.wjso.com/content/7/1/6 Figure lobe image sets demonstrating progressive decrease in the functional and anatomic ... (Figure 3) The patient continued systemic chemotherapy for a total of courses with no significant toxicity noted At 3month follow-up evaluation, based on a favorable tumor response, the patient's...
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Báo cáo y học: "Expression of ADAM15 in rheumatoid synovium: up-regulation by vascular endothelial growth factor and possible implications for angiogenesis" ppt
... interaction, cell migration, signal transduction, shedding of various membrane-anchored proteins and degradation of ECM components under pathophysiological conditions such as fertilization [4,5], ... receptors on endothelial cells enhances not only their proliferation and migration but also production of MMPs [16-18] In addition, VEGF stimulates other cells such as chondrocytes to induce expression ... expressed only neuropilin-1 under unstimulated conditions (Fig 9a) Because the data that VEGF165 stimulated ADAM15 expression only in HUVECs suggested that the effect is dependent on the expression...
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Báo cáo khoa học: "Planning target volume margins for prostate radiotherapy using daily electronic portal imaging and implanted fiducial markers" docx
... estimating intra-fraction motion, because it is based on the comparison of prostate position on only two EPIs, may be less accurate than methods Skarsgard et al Radiation Oncology 2010, 5:52 http://www.ro-journal.com/content/5/1/52 ... of both image- based and contour -based registration methods Analysis based on both geometric and dosimetric parameters Estimated CTV to PTV margins required to allow a dose reduction on the prostate ... extent of variation in prostate position relative to external skin markings, from one fraction to another (inter-fraction motion), and during a single fraction (intra-fraction motion) We found that...
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Báo cáo khoa học: "Value of diffusion weighted MR imaging as an early surrogate parameter for evaluation of tumor response to high-dose-rate brachytherapy of colorectal liver metastase" docx
... for each lesion Initial and follow-up images were matched and ADC calculations were performed on corresponding sections on follow-up MRI (Figure 4) Statistical Analysis SPSS, version 17.0 (Chicago, ... Consecutive restriction of extracellular microcirculation leads to a decrease in ADC Restriction of the extracellular microcirculation in turn may compromise microperfusion through compression ... information on diffusion as well as microperfusion this effect may also have contributed to this early decrease in mean tumor ADC [37-39] Cell swelling and transudation of plasma components into...
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Báo cáo khoa học: "Stereotactic body radiotherapy for stage I lung cancer and small lung metastasis: evaluation of an immobilization system for suppression of respiratory tumor movement and preliminary results" ppsx
... 0.75 mm/second, and the rotation time was seconds under the free-breathing conditions and second under the expiratory and inspiratory breath-holding conditions All CT scans were reconstructed ... movement in condition X minus that in condition Y Page of 10 (page number not for citation purposes) Radiation Oncology 2009, 4:15 http://www.ro-journal.com/content/4/1/15 Right-to-left direction Tumor ... We monitored the change of SpO2 under conditions A, C and D, because we had a concern that SpO2 might decrease by suppression of respiration especially in patients with low pulmonary function...
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Báo cáo khoa học: " Ipsilateral irradiation for well lateralized carcinomas of the oral cavity and oropharynx: results on tumor control and xerostomia" pot
... ipsilateral regions at risk of subclinical disease (PTV2), both for radical and postoperative radiotherapy All patients were treated with continuous, conventional fractionation of Gy, one fraction per ... was to increase the loco-regional control probability As the recommendations for postoperative chemoradiation are relatively recent [23], we found only one publication on patients with high associated ... irradiation for carcinomas of tonsillar region and soft palate based on computed tomographic simulation Radiother Oncol 2000, 54:117-21 Rusthoven KE, Raben D, Schneider C, Witt R, Sammons S, Raben...
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Báo cáo khoa học: " Kinetic modeling of tumor growth and dissemination in the craniospinal axis: implications for craniospinal irradiation" pps
... irradiation Int J Radiat Oncol Biol Phys 1993, 26:905-906 Mu X, Bjork-Eriksson T, Nill S, Oelfke U, Johansson K, Gagliardi G, Johansson L, Karlsson M, Zackrisson D: Does electron and proton therapy ... not cured The model and equations presented herein are a simplification of a complex process Three major assumptions have been made in the model' s creation First is the assumption that the logarithm ... more complex growth models could be employed in this model, using the numerical solution technique described below Based on the above assumptions and in the absence of radiation-induced cell killing,...
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Báo cáo y học: "Targeted genomic capture and massively parallel sequencing to identify genes for hereditary hearing loss in middle eastern families" pot
... analysis of the two common GJB2 mutations, and on occasion, DNA sequencing of the GJB2 coding region In some clinics, screening for the relevant mutations in other genes on the basis of ethnic ... sequencing in combination with homozygosity mapping, as we previously demonstrated [6] Conclusions Multiple mutations responsible for hearing loss were identified by the combination of targeted capture ... protein function (missense, nonsense, truncation), context (coding or non-coding sequence), and if it is in coding sequence, the amino acid change The Placental Mammal Basewise Conservation by PhyloP...
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Tìm thêm: xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25