reversal learning tasks and behavior in pd
Báo cáo khoa học: Relaxin-3⁄ insulin-like peptide 7, a neuropeptide involved in the stress response and food intake Masaki Tanaka pptx
Ngày tải lên :
29/03/2014, 21:20
... relaxin-3 is considered to be different from that of other relaxin proteins involved in the growth and remodeling of reproductive and other tissues during pregnancy [10] In the mouse and rat brain, ... water-restraint stress for 2–4 h induces c-Fos expres- Relaxin-3 expression and function in the hypothalamus sion and leads to an increase in relaxin-3 mRNA levels in the NI [12] On the other hand, ... appetite and the HPG axis) This group includes NPY, orexin and galanin-like peptides [51–54] Conclusions In this minireview, relaxin-3, which is the latest member of the insulin ⁄ relaxin family,...
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Báo cáo y học: "The organisation of the stress response, and its relevance to chiropractors: a commentary" pdf
Ngày tải lên :
13/08/2014, 14:20
... testosterone, TSH and T3 instigating insulin resistance/hyperinsulinemia and dyslipidemia [80] This leads to the exertion of a complex and long-lasting effect involving increased SNS activity and increased ... Catecholamines are involved in these pathways as chemical messengers Brainstem catecholaminergic and noncatecholaminergic neurons, through collateral branching inputs may provide coordinated signaling ... Osteopathy 2006, 14:25 ing corticotrophin releasing hormone, adrenocorticotropin hormone, cortisol, norepinephrine and epinephrine [7] Once the stress response is activated, behavioral and physiological...
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Báo cáo khoa học: Human skin cell stress response to GSM-900 mobile phone signals In vitro study on isolated primary cells and reconstructed epidermis docx
Ngày tải lên :
07/03/2014, 11:20
... the skin or skin cells did not use the same endpoints For instance, in vitro exposure at 900 or 1800 MHz was found to affect gene expression and induce DNA damage in a fibroblastic cell line and ... expression (Fig 6J) In the case of Hsp70 (Fig 6G–I), instead of being expressed only in the cytoplasm as in NHDFe, it was also expressed in the nucleus UVB exposure induced a slight increase in Hsp70 expression, ... mJÆcm2 single dose, h post exposure) Scale bar: 25 lm Human reconstructed epidermis GSM-900 did not induce an in ammatory process in hRE In these experiments using haematoxylin ⁄ eosin-stained reconstructed...
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Báo cáo khoa học: Yeast oxidative stress response Influences of cytosolic thioredoxin peroxidase I and of the mitochondrial functional state pot
Ngày tải lên :
16/03/2014, 14:20
... peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumor suppression Nature 424, 561–565 60 Kinnula VL, Paakko P & Soini Y (2004) Antioxidant ¨ ¨ enzymes and redox regulating thiol proteins in ... phase, treated during 40 with no agent as a control or with 1.2 mM H2O2 and 0.1 lgÆmL)1 antimycin A (anti A), singly or in association, as indicated in the figure The symbols –, + or ± in the last column ... H2O2, 0.1 lgÆmL)1 antimycin A (anti A), and 2.5 lgÆmL)1 FCCP singly or in association Proceedings were performed as described in Fig detectable expression in both wild-type and tsa1D cells: TSA2,...
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Báo cáo khoa học: The crystal structure of annexin Gh1 from Gossypium hirsutum reveals an unusual S3 cluster Implications for cellulose synthase complex formation and oxidative stress response potx
Ngày tải lên :
17/03/2014, 03:20
... calcium binding sites in annexins is conserved in domain I only and is present in a modified form in the fourth domain Despite extensive efforts, we have not yet been successful in obtaining a calcium-bound ... occluding access to the binding site A bidentate ligand required for canonical calcium binding is also missing Membrane binding loops For reasons of homology, it is likely that the AB and DE ... calcium binding in the loops of domain I might be possible in Anx(Gh1), in contrast to the bell pepper annexin The protein contains a highly unusual sulfur cluster formed by two adjacent cysteine...
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Cell Metabolism Cell Homeostasis and Stress Response Part 15 doc
Ngày tải lên :
22/06/2014, 02:20
... Lipids in normal and tumor cells in culture Prog Biochem Pharmacol 10: 135–66 Hu, C.-D., Chinenov Y & Kerppola T.K 2002 Visualization of interactions among bZIP and Rel family proteins in living ... Alternative splicing of tropomyosin premRNAs in vitro and in vivo Genes & Dev 2: 1627-1638 Imaging Cellular Metabolism 203 Hernandez-Verdun, D., Roussel P & Gebranes-Younes J 2002 Emerging concepts ... 2006 PET/CT in patients with hepatocellular carcinoma using [(18)F]fluorocholine: preliminary comparison with [(18)F]FDG PET/CT Eur J Nucl Med Mol Imaging 33: 1285–1289 Ting, A.Y., K.H Kain, R.L...
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Cell Metabolism Cell Homeostasis and Stress Response Part 1 pdf
Ngày tải lên :
22/06/2014, 03:20
... defense-related genes encoding protein-related proteins like glucanase, chitinase or protein inhibitors, and (3) causing cell death in a particular region of the plant (Reilly et al., 2004) During the defense ... proteins, lipids and DNA However, depending on its intracellular concentration, ROS can also function as signaling molecules involved in the regulation and defense responses to pathogens, but mainly ... role in facilitating the defense of plants This can be summarized in the following points: (1) strengthening the cell wall by structural carbohydrate modifications in linkages, (2) the induction...
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Cell Metabolism Cell Homeostasis and Stress Response Part 2 doc
Ngày tải lên :
22/06/2014, 03:20
... and premature leaf abscission (Kozlowski, 1997) The plant response to flooding during the growing phase, including injury, inhibiting seed germination, of vegetative and reproductive growth and ... toxic and not interfere with cellular metabolism The chemical nature of solutes differ among plant species They include betaines, including glycine betaine, amino acids (especially proline) and ... compounds help to maintain turgor during dehydration, increasing the number of particles in solution Furthermore, can modulate membrane fluidity and protein by keeping it hydrated, allowing the stabilization...
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Cell Metabolism Cell Homeostasis and Stress Response Part 4 ppt
Ngày tải lên :
22/06/2014, 03:20
... conditions of continuous ROS production by PETC OH• is considered as the main ROS injuring DNA It preferably attacks the thimines and cytosines, and in a less extent, adenines, guanines, and the rest ... transduction in plants Annual Review Plant Biology, Vol.53, pp.247-273, ISSN 1543-5008 Zielinski, R.E (1998) Calmodulin and calmodulin-binding proteins in plants, Annual Review of Plant Physiology and ... in the aqueous solutions and in the presence of the electron donors and protons O2•− can react as a good oxidant producing H2O2 Ascorbate, quinols, glutathione, and so on can be such donors In...
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Cell Metabolism Cell Homeostasis and Stress Response Part 6 docx
Ngày tải lên :
22/06/2014, 03:20
... ISSN 1369-5266 Mullineaux, P.M (2009) ROS in Retrograde Signalling from the Chloroplast to the Nucleus, In: Reactive Oxygen Species in Plant Signaling Signaling and Communication in Plants, L.A Rio ... chain and ATP production levels, interrupts reserve metabolism (glycogen and trehalose metabolism and glucan synthesis), and regulates the central carbon metabolism and amino acid biosynthesis in ... mammalian PCD in yeast, as indicated by plain homology searches and by the difficulty to explain the sense of cell suicide and its evolutionary advantage in a unicellular organism However, in the late...
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Cell Metabolism Cell Homeostasis and Stress Response Part 8 pptx
Ngày tải lên :
22/06/2014, 03:20
... rich in ATP-actin, the center, rich in ADP-Pi-actin and the pointed end containing ADP-actin Many actin-binding proteins regulate actin polymerization Profilin is an actin monomer-binding protein; ... structural proteins that shapes the cell and has binding sites for different enzymes Such sites have been identified in filamentous actin (F-actin), in microtubules and in the cytoplasmic domain of the ... in Dictyostelium, CapZ prevents filament elongation and increases the concentration of unpolymerized actin; in contrast, in yeast this same protein prevents depolymerization increasing F-actin...
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Cell Metabolism Cell Homeostasis and Stress Response Part 9 doc
Ngày tải lên :
22/06/2014, 03:20
... uranium concentration in drinking water) and urine albumin levels (expressed as mg/mmol creatinine) in adults living in households with elevated uranium levels in drinking water In accordance, Zamora ... 222Ra are released into the environment Workers in uranium mines and the people living nearby are likely to inhale and ingest suspended air particles containing uranium and radon Inhalation of uranium ... fold increase in reported cancers In most of these cases the lung, bronchial tubes, bladder, and skin are damaged In addition, increased incidence of stomach cancer in males and breast cancer in...
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Cell Metabolism Cell Homeostasis and Stress Response Part 11 pot
Ngày tải lên :
22/06/2014, 03:20
... cyclin-dependent kinases (CDKs), unscheduled proliferation, genomic instability (GIN) and chromosomal instability (CIN) In the first case, mutations result in constitutive mitogenic signaling and ... in PDT for cancer treatment includes porphyrins, phthalocyanines, the 5-aminolevulinic acid and chlorine These PSs have been preferentially selected due to their approval for clinical use In ... Pre-clinical and clinical studies have demonstrated that PDT eliminates tumors by direct tumor cell death and indirectly by augmenting anti-tumor immunity An in vitro study showed that PDT caused...
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Cell Metabolism Cell Homeostasis and Stress Response Part 13 doc
Ngày tải lên :
22/06/2014, 03:20
... (Protein kinase C beta type), PRKCA (Protein kinase C alpha type) and also YWHAZ (Protein kinase C inhibitor protein 1) Protein kinase C (PKC) is a family of serine- and threonine-specific protein ... signaling pathways PRKCA also binds to RHOA which is another core protein in Wnt/PCP signaling PRKCB, calcium-activated and phospholipid-dependent serine/threonine-protein kinase, is involved in ... (Wnt/Ca2+ subnetwork) AXIN1 Core protein (β-catenin sub-network) Table 10 Proteins and network crosstalk values Discussion 4.1 Wnt signaling in maintaining homeostasis and managing cellular stress...
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Cell Metabolism Cell Homeostasis and Stress Response Part 14 potx
Ngày tải lên :
22/06/2014, 03:20
... time, in the context of chromatin structure and global nuclear organization Tandem arrays of DNA containing repeated binding sites for fluorescently-tagged DNA binding proteins can be stably integrated ... visualize the kinetics of chromatin unfolding and transcript synthesis in living cells (reviewed in McNally, 2009 and in Rafalska-Metcalf & Janicki, 2007) In one system, integrated tandem arrays ... 2009) Both [11C]Choline and [18F]Choline, are indicators of phospholipid metabolism in cells Choline is transported into cells where it is metabolized to phosphocholine by choline kinase, an enzyme...
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ABIOTIC STRESS RESPONSE IN PLANTS – PHYSIOLOGICAL, BIOCHEMICAL AND GENETIC PERSPECTIVES docx
Ngày tải lên :
28/06/2014, 08:20
... in Plants carboxyterminal calmodulin-like domain containing EF-hand calcium-binding sites plus a N-terminal protein kinase domain (Cheng et al., 2002) Thus, the signaling pathways activated in ... in the intracellular space, several simultaneous pathways are activated by calcium-interacting proteins such as Ca2+-dependent protein kinases (CDPKs), calmodulin and calcineurin Blike proteins ... stresses and in engineering and breeding more efficient and better adapted new crop cultivars This book is broadly divided into sections on signaling in abiotic stress, nucleic acids, proteins and...
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Báo cáo y học: "Stress, the stress response system, and fibromyalgia" ppt
Ngày tải lên :
09/08/2014, 10:20
... blocking the efferent sympathetic supply to the affected region relieves the pain, and with the observation that norepinephrine injections rekindle the pain The sympathetically maintained pain ... Norepinephrine transmits impulses also in peripheral postganglionic nerve endings and exerts its effects locally, in the immediate vicinity of its release, whereas epinephrine is the circulating ... Catecholamines are the sympathetic neurotransmitters The naturally occurring catecholamines are norepinephrine, epinephrine, and dopamine The three substances act as neurotransmitters within the...
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Báo cáo y học: "Is fibromyalgia a cardiovascular disease? A comment on Martinez-Lavin’s review ‘Stress, the stress response system, and fibromyalgia’" ppsx
Ngày tải lên :
09/08/2014, 10:21
... Félix and Fontenele Competing interests The authors cite their own work on the subject that is currently in press There are no potential sources of conflicts of interest References Martinez-Lavin ... symptoms: a lost link between cardiovascular and nociception modulation? J Musculoskeletal Pain, in press Stewart J, Taneja I, Medow MS: Reduced central blood volume and cardiac output, and increased ... Data from LUMINA, a multiethnic cohort J Clin Rheumatol 2007, 13:128-133 Kuchinad A, Schweinhardt P, Seminowicz DA, Wood PB, Chizh BA, Bushnell MC: Accelerated brain gray matter loss in fibromyalgia...
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