resolution and racemization of enantiomers
Báo cáo y học: "Resolution and outcome of acute circulatory failure does not correlate with hemodynamics" doc
... of and grading of the severity of MOF [22] For this study we used SOFA scoring [23] The use of the daily SOFA score has been challenged, because daily evaluation can lead to underestimation of ... the resolution of shock and the development of organ failures Finally, we study the evolution of organ failures and its association with mortality in these critically ill patients Patients and ... study, and still both groups were treated to the same level of filling pressures Other studies have shown that the amount of fluids and blood infused is a surrogate marker of the severity of illness...
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Report and Recommendations of the Cross-border Bank Resolution Group potx
... component of supervisory oversight and take into account cross-border dependencies, implications of legal separateness of entities for resolution and the possible exercise of intervention and resolution ... depositors, treatment of intra-group claims, ranking of claims, rights to set-off and netting, and the treatment of certain financial contracts, submission and admission of claims, and distributions ... the island’s total published reserves and invested funds (less national insurance and pensions) of GBP 922 million and 7.5% of GDP – to partially compensate savers in the Isle of Man branch of KSF...
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Báo cáo khoa học: High resolution structure and catalysis of O-acetylserine sulfhydrylase isozyme B from Escherichia coli pot
... to PLP and not mobile (Fig 5), although it participates in the induced fit (Fig 4) The mobility distributions of CysM(K268A), wildtype CysM and CysM(salmo), and those of subunits B and D of CysM(RKE), ... defines the thiol position of TNB to a small region above the plane of the acrylate double bond As a result of this constraint and of the spacious active center pocket of CysM, TNB was placed rather ... into an average of the closely related subunits B and D and the equally well-related subunits A and C observed asymmetry should reflect a general property of CysM The asymmetry of CysM(RKE) is...
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Báo cáo khoa học: High-resolution crystal structures of the flavoprotein NrdI in oxidized and reduced states – an unusual flavodoxin pot
... seven) and strand b3 by four residues (five versus nine) (Fig and Table S1) In addition, the loops between a1 and b2; a3 and b4; and a4 and b5 are shortened compared to dsFld Analysis of 199 NrdI ... flavin moiety of FMN binds in a pocket formed by loops at the C-terminal ends of b-strands and (loops 42–49 and 71–79, respectively), known in Fld as the W and Y loops, or the 50s and 90s loops ... density for the FMN cofactor is excellent in both structures, and the high resolution of the oxidized form allows confirmation of the protonation Results The crystal structure of baNrdI has been...
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Báo cáo khoa học: Molecular basis for substrate recognition and drug ˚ resistance from 1.1 to 1.6 A resolution crystal structures of HIV-1 protease mutants with substrate analogs pptx
... carbonyl oxygen of Met46¢ and the side chain of Lys45¢ Furthermore, P3 is Arg in CA-p2 and Thr in p2-NC As a result, the carbonyl oxygen of P3 Arg interacted with the amide of Asp29 instead of the interaction ... interactions at P1¢ and P3¢ were enhanced (Fig 6A) mainly by movements of the side chains of P1 Nle and P3¢ Arg ˚ and partially by the small (0.3 A) shift of the CA atom of Ala82 ⁄ 82¢ P1¢-Nle ... such as V82A and I84V Structural comparison of the complexes with the p6pol-PR analog The structures had two conformations of p6pol-PR with relative occupancies of 0.6 and 0.4 and 0.8 and 0.2 for...
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high resolution separation and analysis of biological macromolecules, part a
... the analysis of enzymatically derived mixtures of peptides and also for the analysis of synthetically derived peptides An example of the high -resolution analysis of a tryptic digest of bovine growth ... time of a nonretained solute The development of high resolution separations of peptides and proteins involves the separation of sample components through manipulation of both retention times and ... reversed-phase ligand is also a crucial step for the full experimental validation of the predictions of the solvophobic model and also to advance our understanding of the mechanism of peptide and protein...
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high resolution separation and analysis of biological macromolecules, part b
... to choice of ligand, ligand attachment, buffers, and sample recovery techniques were reviewed A specific example of AFC of peptides offered was that of examining the binding affinities of multiple ... elution time of Mb, cyanogen bromide fragments of Mb and the live synthetic peptide standards Peptide standards 1, 2.3, 4, and contain 10, 20, 30, 40, and 50 residues, respectively, and their sequences ... sequences of standards 1, 2, and (10, 20, and 50 residues and + 1, +2, and +5 net charge, respectively) are shown in Table The arrows denote the elution time for the total permeation volume of Ihe...
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Báo cáo sinh học: "High-resolution quantitative imaging of mammalian and bacterial cells using stable isotope mass spectrometry" docx
... variety of spatial resolutions We analyzed one of the bundles of stereocilia (Sb1, indicated by a white arrow in Figure 3a) at high resolution; we used a field of x m, a beam size of about 35 nm, and ... and uniform carbon content The image of the 13C- ions (Figure 3e) is similar to the 12Cimage, but with a much lower count rate; the total number of counts of 13C- and of 12C- are 2.56 x 105 and ... Qualitative co-localization of DNA and RNA through simultaneous imaging of RNA and DNA Rat embryo fibroblasts were pulsed with 15N-uridine and BrdU as markers of newly synthesized RNA and DNA, respectively...
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Báo cáo y học: "High resolution discovery and confirmation of copy number variants in 90 Yoruba Nigerians" pdf
... RR and GF conceived the experiments and designed the genome-scan arrays HM and GF designed the typing array PW and GF prepared samples and hybridized the arrays PW, GF, and HM ran PCRs HM and ... matches The number of observed or reported events in the common Yoruba, and the percentage of these events that were matched and compared, give an indication of the extent of missed events in ... thorough catalog of shorter CNVs in the genome, including an assessment of the age of these variations Even at a resolution of approximately 200 bp, our genome scan detected only a fraction of the CNVs...
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Mechanisms and functions of lymphangiogenesis in regulating the immune response and inflammation resolution 2
... population in WT and µMT mice following immunization (C) Immunofluorescence analysis of WT and µMT LN sections (D and E) Expansion of the BEC (D) and FRC (E) populations in inflamed µMT LNs mice following ... event vital for timely resolution of inflammation In the absence of early lymphangiogenesis and inflammation resolution, a vicious cycle whereby arrested lymphangiogenesis and chronic inflammation ... governed distribution of VEGF-A into the paracortex and medulla To further support this, disruption of interstitial flow was noted to obliterate association of VEGF-A with cortical and medullary sinuses...
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Mechanisms and functions of lymphangiogenesis in regulating the immune response and inflammation resolution 1
... Culture of hybridoma cells and purification of antibodies… .39 2.9 Treatment of mice with antibodies and FTY720… 40 2.10 Dendritic cell migration assay ……… 41 2.11 Disruption of lymphatic ... that the subcapsular sinuses and medullary and cortical sinuses were differentially expanded during the early and late phases of inflammation, respectively Expansion of the subcapsular sinuses ... et al., 2009) and lymphotoxin-α (LT-α) (Mounzer et al., 2010) have both been reported to drive remodeling and function of blood and lymphatic vessels in several models of infection and inflammation...
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Development of multivariate curve resolution and associated system identification tools for IR emission, chiroptical, and far infrared and far raman spectroscopies
... DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF CHEMICAL & BIOMOLECULAR ENGINEERING NATIONAL UNIVERSITY OF SINGAPORE 2007 ACKNOWLEDGEMENT This thesis is the result of four and half years of work ... distinguishable spectrum and that the concentration profile of the component does not completely encase the profile of any other component (Zhao and Malinowski, 1999) The ‘window’ of a component refers ... reduction in the amount of computation required and eradication of the problem associated with over -resolution This was the birth of a new curve resolution method named band target entropy minimization...
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A study of detection of enantiomers and chemical analogues by molecular imprinted polymer coated quartz crystal microbalance technique
... Research projective and scope Detection and separation of enantiomers are one of the most attractive and promising techniques which is much more important especially in pharmacy and drug industry ... representation of process of adsorption and desorption in MIP Figure 1.3 Schematic of a typical piezoelectric crystal Figure 1.4 AT-cut of a quartz crystal Figure 1.5 Schematic representation of a MIP-coated ... diagnosis of hereditary and infectious diseases In addition to electrochemical and optical detection of DNA, mass-sensing devices were also added to the repertoire of signal transducers capable 20 of...
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Chapter 4: Getting Images into and out of Photoshop
... border to clean up the edges of the selected area of color ߜ Smooth: When you click with the Magic Wand to make a selection of an area of color, you might see all kinds of tiny 1- or 2-pixel areas ... again, and repeat a number of times to create a series of paw prints marching into the distance Figure 8-14: The many faces of transformations The mask-related selection commands At the bottom of ... terms as you read about the various tools and commands with which you make selections Both feathering and anti-aliasing make the edges of your selections softer by using partially transparent or...
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SAP2000® Linear and Nonlinear Static and Dynamic Analysis and Design of Three-Dimensional Structures
... and all associated documentation are proprietary and copyrighted products Worldwide rights of ownership rest with Computers and Structures, Inc Unlicensed use of the program or reproduction of ... trademark of Microsoft Corporation Adobe and Acrobat are registered trademarks of Adobe Systems Incorporated DISCLAIMER CONSIDERABLE TIME, EFFORT AND EXPENSE HAVE GONE INTO THE DEVELOPMENT AND DOCUMENTATION ... bridge spans 60 feet, and has a width and height of 12 feet each The supports are rollers at one end, and pins at the other The trusses and cross members are to be constructed of 2L4X4’s, while the...
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SAP2000 Integrated Finite Elements Analysis and Design of Structures
... and all associated documentation are proprietary and copyrighted products Worldwide rights of ownership rest with Computers and Structures, Inc Unlicensed use of the program or reproduction of ... trademark of Microsoft Corporation DISCLAIMER CONSIDERABLE TIME, EFFORT AND EXPENSE HAVE GONE INTO THE DEVELOPMENT AND DOCUMENTATION OF SAP2000 THE PROGRAM HAS BEEN THOROUGHLY TESTED AND USED ... title of the window reads YZ Plane @ X=24 This same title also occurs on the left-hand side of the status bar at the bottom of the SAP2000 window Click the roof level beam on the left side of the...
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The Design and Implementation of a Log-Structured File System
... areas of cost and capacity rather than performance There are two components of disk performance: transfer bandwidth and access time Although both of these factors are improving, the rate of improvement ... us to understand the effects of random access patterns and locality, both of which can be exploited to reduce the cost of cleaning The simulator models a file system as a fixed number of 4-kbyte ... on disk and in terms of how much of the data written to the log they represent More than 99% of the live data on disk consists of file data blocks and indirect blocks However, about 13% of the...
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The Breadth and Depth of DSP
... generation and recognition are used to communicate between humans and machines Rather than using your hands and eyes, you use your mouth and ears This is very convenient when your hands and eyes ... very specialized audience State -of- the-art researchers need this kind of detailed mathematics to understand the theoretical implications of the work A basic premise of this book is that most practical ... -Simulation and modeling FIGURE 1-1 DSP has revolutionized many areas in science and engineering A few of these diverse applications are shown here Chapter 1- The Breadth and Depth of DSP in many...
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Cambridge.University.Press.Fearing.Others.The.Nature.and.Treatment.of.Social.Phobia.Mar.2007.pdf
... Social phobia and disruptive social anxiety are features of the lives of many thousands of people But exactly what is social phobia? What causes it? What is its nature and what kinds of treatments ... key concepts and methods and a substantive body of research, this book aims to answer these questions and clarify social phobia by means of critical discussions and examination of evidence It ... clinicians, and students in clinical and health psychology and psychiatry AR I E L ST R AV Y N S K I is Professor of Clinical Psychology in the Department of Psychology at the University of Montreal...
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Characterization and deactivation of sulfided red mud used as hydrogenation catalyst
... These samples, and samples of fresh unsulfided and sulfided catalyst, were characterized by nitrogen adsorption and SEM The results of textural characterization by nitrogen adsorption of the catalyst ... related to the intensity of emission of the characteristic Ka line of each element White corresponds to a high concentration of a given element, and black to the absence of this element, while ... Fig SEM-EDX maps of distribution of elements: red mud after h run time The brightness of every pixel of the EDX maps, B, can be quantified on a scale of (black) to (maximum degree of brightness)...
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