resistance evasion of the immune response and aids pathogenesis
Báo cáo y học: "Circulating adenosine increases during human experimental endotoxemia but blockade of its receptor does not influence the immune response and subsequent organ injury" pdf
Ngày tải lên :
14/08/2014, 07:21
... supervised the genetic analyses and the writing of the manuscript WHMP performed the GSTA1-1 and GSTP1-1 analyses PP, NPR, and PS supervised the conduct of the study and the writing of the paper ... aggravated In the presence of the 34C > T variant of the AMPD1 gene, the inflammation-induced increase in adenosine concentration is augmented, and therefore the inflammatory response and organ injury ... Nijmegen, The Netherlands Authors’ contributions BPR carried out the study, gathered all data, performed the statistical analysis and wrote the manuscript PvdB performed the adenosine and caffeine...
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Mechanisms and functions of lymphangiogenesis in regulating the immune response and inflammation resolution 2
Ngày tải lên :
09/09/2015, 18:48
... through the LN could influence the spatial-temporal distribution of VEGF-A during the course of inflammation and, as a consequence, modulate the remodeling of cortical and medullary sinuses As other ... of the LN The heparin-binding carboxyl-domain of the predominant VEGF-A isoform, VEGF164 may bound the molecule to the extracellular matrix and limit its access deeper into the LN via the reticular ... indispensable for the occurrence of lymphangiogenesis in µMT LNs, it is unlikely that they were the only cells driving the process Depletion of monocytes and macrophages by the use of AFS98 MAb inhibited...
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Mechanisms and functions of lymphangiogenesis in regulating the immune response and inflammation resolution 1
Ngày tải lên :
09/09/2015, 18:48
... reabsorbed at the venous side of the capillary bed, where the colloid osmotic pressure of the blood exceeds the blood pressure The main function of the lymphatic vasculature is to return the remaining ... and so forth The mouse isoforms are one amino acid residue shorter than the corresponding human isoform and they are denoted as VEGFA120 and so forth Human VEGF-A121, VEGFA165, VEGFA189 and their ... 2009) There is a wealth of evidence indicating that differences in the expression of the NRPs and heparin-binding domains give rise to the diverse biochemical and functional properties of the VEGF-A...
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Báo cáo Y học: A new siglec family member, siglec-10, is expressed in cells of the immune system and has signaling properties similar to CD33 docx
Ngày tải lên :
24/03/2014, 04:21
... digesting the fragment with HindIII and Bgl II and the plasmid with HindIII and Bam HI The fragment was ligated into the plasmid and the integrity of the insertion was validated by digesting the plasmid ... positions 597, 641, 667, and 691 To construct the GST fusions of the tandem SH2 domains of each SHP-1 and SHP-2, the sequences corresponding to amino acids 2–232 of each SHP-1 and SHP-2 were amplified ... purified (< 820 bp) The insert was then ligated into the pSPORT vector and the resulting full-length siglec-10 clone was designated 995-2 and the sequence was verified against the other siglec-10 clones...
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Báo cáo y học: " Characterisation of the immune response to type I collagen in scleroderma" pps
Ngày tải lên :
09/08/2014, 08:22
... progression, and immune responses to CI However, the importance of immunity to CI is emphasised by the finding that oral administration of CI to patients with SSc modulates T-cell responses and may ... characterization of the autoimmune T cell response in the HLA-DR1 mouse model of collagen-induced arthritis reveals long-term activation of type II collagen-specific cells and their presence in ... = 0.359) None of the SSc-related disease manifestations was predictive of an immune response to CI in vitro, except for a trend toward more lung fibrosis in the CI responders Of the CI responders,...
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Báo cáo y học: "The organisation of the stress response, and its relevance to chiropractors: a commentary" pdf
Ngày tải lên :
13/08/2014, 14:20
... projects to the lateral hypothalamus to mediate the activation of sympathetic component of the ANS [36]; projections to the dorsal motor nucleus of the vagus are involved in the activation of the parasympathetic ... major role of the endocrine cytokines in the immune stimulation of the HPA axis [73] Chronic activation of the stress response has been found to impair immune functions, and delay the healing ... [79] The role of the HPA axis is crucial to regulating the severity of autoimmune disease, though the cause remains obscure In the absence of corticosteroids the immune system is unrestricted and...
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Báo cáo y học: "Using an agent-based model to analyze the dynamic communication network of the immune response" docx
Ngày tải lên :
13/08/2014, 16:20
... ticks The plots show the frequency distribution of the contacts as log10 of the number of nodes vs the log10 of the number of links per node for the first 400 ticks of the simulation for the given ... “engaged” in the immune response, and the extent of engagement of each agent type for the response duration was determined Zero percent of the agents were engaged at the start of a simulation run The ... distributions of contacts for each immune agent type at 1000 ticks The plots show the frequency distribution of the contacts as log10 of the number of nodes vs the log10 of the number of links per...
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Báo cáo y học: "Bench-to-bedside review: Functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis" ppsx
Ngày tải lên :
12/08/2014, 19:21
... the exoskeleton of the crab immediately jeopardizes the integrity of the internal milieu of the organism Not only is there a real threat of loss of internal contents of the crab to the external ... integument of the animal, and it seals off the injured area from the remainder of the crab’s open circulatory system The animal will often clot off and sacrifice an entire extremity (they have ... the host, with consumption of clotting factors and widespread deposition of fibrin clots throughout the microcirculation [2,19–21] The actions of the human coagulation system and the innate immune...
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Retrieval of the source location and mechanical descriptors of a hysteretically-damped solid occupying a half space by full wave inversion of the the response signal on its boundary doc
Ngày tải lên :
18/03/2014, 01:21
... of the RM is chosen to be the same as the MNI of the SM In this case, when the values of all the parameters of the set P are strictly equal to their counterparts in the set p and the values of ... cartesian coordinates of the position of the receiver on the ground and (0, 0) the position of the emitter, also on the ground, of the probe signal The present study is restricted to the case in which ... reliable retrieval of the imaginary part of ℑµ for ±10% discordance of any of the other mechanical descriptors or of x1 On the other hand, it was shown that a ±10% discordance of the mechanical...
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báo cáo hóa học:" Reliability and validity of Thai versions of the MOS-HIV and SF-12 quality of life questionnaires in people living with HIV/AIDS" pot
Ngày tải lên :
20/06/2014, 15:20
... scale score within the MOS-HIV and SF-12 and the proportion of minimum and maximum responses were determined to assess the impact of floor and ceiling effects for each scale The reliability, or ... Discussion The results of this initial test provide evidence for acceptable reliability and validity of the Thai versions of the MOS-HIV and SF-12 as measures of HRQOL among HIV+ patients in Northern ... was also conducted for the summary scores of the SF-12 and MOS-HIV using a series of dichotomized variables for CD4 count, SDM score, number of bed days, and number of days of reduced activity CD4...
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Báo cáo hóa học: " Signal Processing in High-End Hearing Aids: State of the Art, Challenges, and Future Trends" pptx
Ngày tải lên :
23/06/2014, 01:20
... delayed and subtracted from the signal picked up by the front microphone The directivity pattern of the system is defined by the ratio r of the internal delay Ti and the external delay due to the ... transform of an input signal block For the determination of the filter weights, the knowledge of the distribution of the real and imaginary parts of Signal Processing in High-End Hearing Aids 2921 ... aid.) and the feedback signal is in phase, instabilities occur and whistling is provoked The feedback path describes the frequency response of the acoustic coupling between the receiver and the...
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current conditions and assessment on the effects of the caring, supporting and treating activities for aids patients at adult outpatient clinics in 3 provinces of vietnam, 2009 - 2010
Ngày tải lên :
25/07/2014, 13:57
... and count the time for the next dosage (82.7%), 16.3% of them skip the missed dosage and take the next dosage as usual, 1.0% of them did not know what to when they missed one dosage Most of the ... situation of HIV /AIDS infection According to the report at the end of year 2010 by UNAIDS and WHO, the whole world has about 70 million of infected people, 30 million of dead persons and currently, there ... to evaluate the efficiency of AIDS patient care, support and treatment at the outpatient clinics and then extend the program to meet AIDS patients’ increasing demand of care, support and treatment...
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study on the immune response of orange spotted grouper (epinephelus coioides hamilton, 1822) cultured in khanh hoa province to bacteria vibrio parahaemolyticus
Ngày tải lên :
26/07/2014, 09:58
... causing the ulcerative disease in grouper Study on the effect of oral administration β-glucan on the native immune response of orange-spotted grouper Study on the specific immune response of orange-spotted ... haemorrhagic septicemia and ulceration of the skin, fins and tail are common symptoms of this disease The disease causes severe infection and often result in high mortality The common agents of this disease ... killed cells of V parahaemolyticus Significance and new conclusions from this dissertation The results of the dissertation contribute with scientific information about the immune response of orange-spotted...
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Báo cáo sinh học: "Parasite immunomodulation and polymorphisms of the immune system" ppsx
Ngày tải lên :
06/08/2014, 19:20
... well recognized for the regulation of immune responses The effect of parasites, for example, has been to dampen, rather than fully ablate, immune responsiveness, and the degree of immunosuppression ... controlling both innate immune responses (such as the IL-1 family) and adaptive Th2 responses (such as IL-4 and IL-4R) Strikingly (in terms of the hygiene hypothesis) out of alleles known to predispose ... deeper understanding of the intimate co-evolution of pathogens and the immune system 10 11 12 13 14 Acknowledgements The author’s research is supported by grants from the Wellcome Trust, the Medical...
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Báo cáo khoa học: "Preliminary study of the monoterpene response of three pines to Ophiostoma clavigerum (Ascomycetes : Ophiostomatales) and two chemical elicitors" pot
Ngày tải lên :
08/08/2014, 23:22
... beetle and its associated fungus However, the nature and the origin of the chemical elicitor responsible for the stimulation of the parenchyma cells is not clear In a previous paper, we reported the ... Raffa and Berryman (1982a), Schuck (1982) and Delorme and Lieutier (1990) noted an increase of the total monoterpene content of phloem and sapwood in the induced reactions of P contorta, Abies grandis ... not to define the qualitative re- sponse of these species but rather to compare the terpene composition of responding tissues with that of unwounded tissues of the same tree Although there is a...
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Báo cáo y học: "Application of in vivo microscopy: evaluating the immune response in living animals" pps
Ngày tải lên :
09/08/2014, 07:20
... occurred even in the presence of antigen These encounters of rapidly migrating T cells with DCs occurred preferentially in the vicinity of HEVs [25] The role of these early and short-lived interactions ... technique Moreover, the development of fluorescent fusion proteins and other indicators of signaling and differentiation events would allow the characterization of the functional capacity of DCs at distinct ... deepening understanding of the complex cellular choreography that is required for the initiation of a coordinate and appropriate immune response Competing interests The author(s) declare that they have...
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Báo cáo khoa học: " Preoperative external beam radiotherapy and reduced dose brachytherapy for carcinoma of the cervix: survival and pathological response" potx
Ngày tải lên :
09/08/2014, 10:21
... brachytherapy doses There are a few reasons that may justify the use of post irradiation surgery They are mostly related to the accomplishment of the pathological staging of the tumor and to the ... pelvic radiotherapy followed by high dose rate brachytherapy and hysterectomy yield a 5year OS of 63% and CSS of 73% These results are similar to our own experience with exclusive RT and to other published ... in two weekly insertions of Gy The median dose of brachytherapy to point A was 12 Gy (range 6–15 Gy) and the mean point A dose was 11.8 Gy According to the beliefs of the assistant physician,...
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Báo cáo y học: "A comparison of the MOS-HIV and SF-12v2 for measuring health-related quality of life of men and women living with HIV/AIDS" pptx
Ngày tải lên :
10/08/2014, 05:21
... contributions AI and MS conceived the design of the study, performed and interpreted the statistical analysis and helped to draft the manuscript FS participated in the design of the study and helped ... clinical and observational HIV research; there is no evidence that the SF-39, a similar HRQoL scale, has ever been used in HIV research The continuous PHS and MHS of the MOS-HIV and the PCS and MCS of ... because of the lack of skew in the distributions of the summary scores Pearson correlation coefficients were used to investigate the relationship between common subdomains of the MOS-HIV and SF-12v2...
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báo cáo khoa học: " Public health the leading force of the Indonesian response to the HIV/AIDS crisis among people who inject drugs" doc
Ngày tải lên :
11/08/2014, 18:20
... Jakarta and West Java (two of the main provinces of Indonesia) is to lead the response and use the infrastructure of the health system to scale the response to the level of the epidemic The expansion ... accurate; there is as well the need to increase quality of data collection and flux of the information Currently, there are many bodies of the Government playing a role in the control of the HIV /AIDS ... Description of the response so far and the role of IHPCP The Indonesian response to the HIV /AIDS crisis among people who inject drugs is still modest There is a clear consensus among stakeholders of an...
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Báo cáo y học: "A poxvirus Bcl-2-like gene family involved in regulation of host immune response: sequence similarity and evolutionary history" pptx
Ngày tải lên :
12/08/2014, 04:20
... B15, K7 and N1, and may support a possible role in immune response evasion of the members of these families with still unknown function The above findings have implications in the use of poxviruses ... structure The same interaction is also conserved in K7 (Arg37 and Asp61) and A52 (Arg67 and Asp87) proteins On the other hand there are a number of charged residues which are exposed on the surface of ... classified in the Orthopox_N1 family Because of the importance of host immune response modulation for poxviruses we hypothesized the existence of additional genes involved in this role among those of still...
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