republican partisan use of criminal libel against federalist critics in the connecticut federal courts under federal criminal common law

REPRESSIVE JURISPRUDENCE IN THE EARLY AMERICAN REPUBLIC

Ngày tải lên : 07/12/2015, 00:59

... Supping with the Devil: Republican Partisan Use of Criminal Libel Against Federalist Critics in the Connecticut Federal Courts Under Federal Criminal Common Law The Constitutional Issue: Did the ... Jefferson and Criminal Libel 184 Partisan Prosecutions for Criminal Libel in the State Courts: Federalists Against Republicans, Republicans Against Federalists, and Republicans Against Dissident Republicans ... prosecutions of Federalists to continue These were six indictments in Connecticut of Federalists under the federal criminal common law The cases were instituted by the Republican District Attorney at the...

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Revised version for the consideration of Contact Committee of the Heads of the SAIs of the European Union docx

Ngày tải lên : 06/03/2014, 23:20

... from the other members of the audit team In some SAIs, the drafting process is supervised by an official who is superior in the hierarchy to the principal auditor 2.5.7 In drafting the report, the ... direction of staff to whom work is delegated involves informing them of their responsibilities and the objectives of procedures they are to perform It also involves informing them of matters such as the ... the Liaison Officers Meeting on 4-5 October In conclusion, the Contact Committee of Heads of the Supreme Audit Institutions of the Member States of the European Union and the European Court of...

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Báo cáo khoa học: "A CONSIDERATION ON THE CONCEPTS STRUCTURE AND LANGUAGE IN RELATION TO SELECTIONS OF TRANSLATION EQUIVALENTS OF VERBS IN MACHINE TRANSLATION SYSTEMS" doc

Ngày tải lên : 31/03/2014, 17:20

... associated in common to a part of the structure of the categories as in Fig.l, and then find appropriate translation equivalents in detail at the lower level categories (2) To each verb found in the ... process of the association, consults ordinary dictionary of translation equivalents and word usage of verbs and obtain the set of all the translation euqivalents for the verb (3) Then find nouns ... as the most closely related verb in this ease It can generally be said that the more the noun's relation to human becomes closer and the more the level of abstract of the noun becomes lower the...

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Comparison of Methods for the Extraction of Bioflocculants from Activated Sludge

Ngày tải lên : 05/09/2013, 09:08

... of the UV-absorbing peak indicated it was composed mainly of nucleic acid In the profile of the NaOH-extracted polymer (B), the elution volume (80 ml) of saccharide corresponded to that of the ... Ag-protein stain, the components varied greatly by polymer Several bands demonstrated the same mobility in both stains, suggesting that these bands were complexes of protein and saccharide These included ... included the band corresponding to a molecular weight of 103,000 in the steaming-extracted polymer (1), the band corresponding to 38,000 in the NaOH-extracted polymer (2), the band corresponding to...

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AN ACTION RESEARCH ON THE EFFECTS OF PRE WRITING ACTIVITIES ON THE GRADE – 11 NON – MAJOR ENGLISH STUDENTS’ MOTIVATION IN WRIT

Ngày tải lên : 07/09/2013, 13:58

... paper with the number indicating the trends of falling, increasing… .The students might be successful in writing this kind of exercise because there were a large number of students repeated these expressions ... questions and scaling Other sources of data come from writing tasks from the textbooks The analysis of the data hopefully will bring about reliable findings useful for the teaching of writing to non ... in taking part in this stage STEP 2: FINDING CAUSES OF THE PROBLEM II.1.4 Consulting with colleagues In order to get more professional advice, suggestions and ideas about the problem of finding...

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Tài liệu Báo cáo khoa học: The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid ppt

Ngày tải lên : 16/02/2014, 09:20

... produced (Fig 1D, lane 2) In the presence of lactacystin, a signiﬁcant increase in the amount of tBid–GFP present in the extract, both in control conditions and in the presence of FLAG–Itch, was observed ... protein of the Bcl-2 family that is crucial for death receptor-mediated apoptosis in many cell systems [16,17] The BH3 domain-only proteins are a subfamily of the Bcl-2 family involved in the initiation ... were present in the extracts, showing that the truncated active form of Bid can indeed bind to Itch (Fig 1A), whereas the full-length protein is prevented to so To determine if the interaction...

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Tài liệu Báo cáo khoa học: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle doc

Ngày tải lên : 18/02/2014, 11:20

... domain binds to pYi on the C-terminal tail, and the Src homology (SH3) domain binds to the linker between the SH2 and kinase domains at the back of the small lobe, preventing the formation of ... behavior by presenting the pulse of Src activity in the plane of the inactive and active fractions, si and s1 If the duration of the stimulus exceeds the critical value, the trajectory in the (si, s1) ... activating and inhibitory stimuli and more moderate changes in the amplitude of the oscillations An increase in the activating signal or decrease in the inhibitory signal decreases the period of...

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Tài liệu Báo cáo khoa học: The effect of small molecules in modulating the chaperone activity of aB-crystallin against ordered and disordered protein aggregation pdf

Ngày tải lên : 18/02/2014, 16:20

... effect on the chaperone activity of aB-crystallin against the DTT-induced aggregation and precipitation of insulin B C Fig aB-crystallin protects against the DTT-induced aggregation of insulin, and ... aB-crystallin against the DTT-induced precipitation of insulin [27,28] These studies also showed that 100 mm Arg-HCl increases the chaperone activity of a-crystallin against the thermally induced ... aggregation of some proteins by acting on the unfolded state of the protein and increasing the reversibility of unfolding [37] Arginine had no effect on the stability of the protein’s native...

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Tài liệu Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases docx

Ngày tải lên : 19/02/2014, 06:20

... through the exchange between subunits of either their N-terminal, or their C-terminal ends [33–35] We found that the behavior with the model membrane of the dimer in which the C-terminal ends ... Nter are the C-terminal and N-terminal structural regions, respectively, of the two A and B monomers of the dimeric RNase The black circle between the monomers indicates the mass center of the dimer ... M, GR and GM are the grid energies of the complex, of the RNase alone and of the membrane alone, respectively The following delphi parameters were used for the calculations of the grid energy...

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Tài liệu Báo cáo khoa học: Oxidized elaﬁn and trappin poorly inhibit the elastolytic activity of neutrophil elastase and proteinase 3 pdf

Ngày tải lên : 19/02/2014, 07:20

... 50% inhibition of Pr3 by the oxidized inhibitors While the above data are in overall agreement with the results obtained using synthetic substrates, they also indicate that elastin hinders the inhibition ... of insoluble extracellular matrix proteins, such as elastin, collagen, ﬁbronectin and laminin? We have shown that the main effect of inhibitor oxidation is an increase in the rate of enzyme–inhibitor ... inhibitor, regardless of the enzyme, the inhibitor and the state of oxidation of the latter, indicating that elastin does not simply act as a competing substrate but also hinders the inhibition process,...

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Tài liệu Báo cáo khóa học: The effect of mutations surrounding and within the active site on the catalytic activity of ricin A chain pptx

Ngày tải lên : 19/02/2014, 12:20

... C1 of the hexanucleotide is at the bottom left and the target adenine is at the top of each model The sidechains of RTA are shown in blue (A) Model has the tetraloop bound in the active site of ... modiﬁcation of arginyl residues 196, 213, 234 and 235 [9] Of theses residues, only Arg213 is in the vicinity of the active site of RTA In order to establish the role of arginyl residues around the active ... 37 °C Protein synthesis was measured by incubating the plates for 90 at 37 °C in the presence of lCi of (35S)methionine in 50 lL of NaCl/Pi per well Proteins were precipitated by washing three...

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Tài liệu Báo cáo khoa học: The phosphatase activity of the isolated H4-H5 loop of Na+/K+ ATPase resides outside its ATP binding site docx

Ngày tải lên : 19/02/2014, 16:20

... the N-domain (overview) (A) Docking of pNPP to the ATP binding site of the model containing N- and P-domains [20] The amino acids interacting with the adenine ring of ATP may also interact weekly ... truncation of the P-domains N-terminal part, caused a drop of the phosphatase activity (Fig 4) The latter nding points to a stabilizing effect of the N-terminal sequence in forming the pNPP site in the ... around N398 at the rear site of the N-domain (pNPP site) of the same model (C) Docking of pNPP to the ATP binding site of the model containing the N-domain only, modeled according to Hakanssons...

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Tài liệu Báo cáo khoa học: Second messenger function and the structure–activity relationship of cyclic adenosine diphosphoribose (cADPR) doc

Ngày tải lên : 20/02/2014, 01:20

... cyclized between N1 of inosine and C2 of the northern ribose [60] In addition, 8-Br-N1-cIDPR induced Ca2+ signalling in 4594 intact T-cells [61,62] This ﬁnding was surprising since 8-Br-N1-cADPR ... nucleobase and the diphospho-bridge, but on the other hand likely are involved in polar interactions with the cADPR receptor protein Certainly, the natural linkers, the northern and southern ribose ... molecule either the polar interactions with its interacting protein were fully replaced by the amino group or that no or only minor ligand protein interactions took place Astonishingly, another modiﬁcation...

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Tài liệu Báo cáo khoa học: A role for the intersubunit disulﬁdes of seminal RNase in the mechanism of its antitumor action docx

Ngày tải lên : 20/02/2014, 11:20

... reconstituted in the presence of growing broblasts into the parent dimeric protein, which is internalized as a native-like dimeric RNase They also indicate for the rst time that when BS-RNase is internalized ... be tested as such for inhibition by CRI, because the strongly reducing conditions of the assay produce the cleavage of their mixed disuldes This in turn generates, from either MSSAE or MSSG, M(SH)2 ... cysteine residues originally involved in the intersubunit disulde bonding of BS-RNase, are irreversibly blocked through S-alkylation In the active MSSAE and MSSG monomers, instead, the two Cys residues...

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Tài liệu Báo cáo khoa học: Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia pptx

Ngày tải lên : 20/02/2014, 23:20

... suppression of respiration during hypoxia In the absence of differential regulation of a speciﬁc nuclear gene coding for the subunits of CytOX, changes in the microenvironment of the cell may induce ... the effects of hypoxia on the steady state levels of nuclear genome encoded CytOX IV and Vb mRNAs There was no change in the levels of these mRNAs in macrophages at h of hypoxia, the time point ... assayed in membrane fragments (SMP) by the method of Smith [20], wherein the rate of oxidation of ferrocytochrome c was measured by following the decrease in absorbency of its a band at 550 nm The...

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Tài liệu Báo cáo khoa học: Coordination chemistry of iron(III)±porphyrin±antibody complexes In¯uence on the peroxidase activity of the axial coordination of an imidazole on the iron atom ppt

Ngày tải lên : 21/02/2014, 03:20

... 1) The binding of the ®rst CN± ligand to the iron was thus more easy in the hydrophobic binding pocket of the antibody than the binding of the second one, most probably because of the steric hindrance ... moiety was inside the antibody pocket with three pyrrole rings packed tightly against residues of the VH domain and two pyrrole rings packed against tyrosine residues of the VL domain Binding of imidazoles ... the iron of free Fe(ToCPP) In addition, the in uence of the nature of the substituent was different in both cases In the case of Fe(ToCPP), it did not cause any steric hindrance for the binding...

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Tài liệu Báo cáo khoa học: Characterization of the promoter for the mouse a3 integrin gene Involvement of the Ets-family of transcription factors in the promoter activity doc

Ngày tải lên : 21/02/2014, 03:20

... inserted into the KpnI/SacI site of Fig Structures of the 5¢-flanking region of mouse a3 integrin gene The map (upper line) shows the organization of exons 1–3 and the 5¢-flanking region with the positions ... factors including Ets, GATA, and MyoD/E-box binding factors The introduction of mutation into one of the putative Etsbinding sequences suppressed the promoter activity In addition, the specific binding ... assay (EMSA) using the Ets consensus site at )133 As the involvement of the Ets consensus binding site at )133 in the promoter activity of the mouse a3 integrin gene was suggested by the luciferase...

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Tài liệu Báo cáo khoa học: The molecular surface of proteolytic enzymes has an important role in stability of the enzymatic activity in extraordinary environments pptx

Ngày tải lên : 21/02/2014, 03:20

... with the amino group of the main chain at Glu268 The oxygen of the main chain at Asp266 was bound to amino groups of main chain of Tyr269 and Ala270 by hydrogen bonds The interactions should maintain ... temperature indicates the stability of the structure of the protein The difference of the increments between the inactive temperature and the Tm should indicate that the mutations improved the stability ... surrounding residues of the depression, and the side chain of the mutated residue might restrain the mobility of the N-terminal region on the surface by interaction with the main chain of Lys26 by van...

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Tài liệu Báo cáo Y học: Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis potx

Ngày tải lên : 21/02/2014, 15:20

... since the heat evolved representing this activity is included in the baseline of the experiment Therefore, the assay only measures the rate increase due to the addition of GTP with a resulting ... described in the legend to the indicated Fig Glutaminase refers to hydrolysis of glutamine without CTP synthesis taking place b In the absence of GTP c Saturated with GTP d The other kinetic parameters ... [S]syr is the concentration of the injectant in the syringe Analysis of initial velocity data Analysis of saturation curves was performed by nonlinear regression using 5ị where kcat,inh is the turnover...

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Báo cáo khoa học: Binding of cGMP to the transducin-activated cGMP phosphodiesterase, PDE6, initiates a large conformational change involved in its deactivation ppt

Ngày tải lên : 06/03/2014, 00:21

... that the lack of Mg2+ in the assay mixture does not affect the afﬁnity of Pabc for cGMP Roles of cGMP binding in PDE6 regulation Binding of cGMP to Pabc is not involved PDE activation Binding of ... that of Pabcdd (data not shown) These results indicate that Pd binding to the lipid moiety of Pab does not affect the level of [3H]cGMP-binding activity in Pabc, implying that membrane binding of ... homogenates are incubated with GTPcS, the Pab content in membranes is increased 20–30% by binding of the Pab ⁄ Pc complex existing in the soluble fraction [13] Therefore, binding of the Pab ⁄ Pc...

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