removal examination and sampling of the liver
Tài liệu Báo cáo Y học: Purification, characterization, cloning, and expression of the chicken liver ecto-ATP-diphosphohydrolase pot
... concentration of mM at pH 7.4 On the other hand, the CaADPase activity is 80% of the MgADPase activity at a divalent ion-ADP concentration of mM (data not shown) The ATPase and ADPase activities of the ... in the apical membranes of the oxyntic-peptic cells [37] The distribution of the ectoATPDase on these epithelial cells is distinctly different from the other ATPDase in the E-ATPase family, the ... numbers are on the right side of the figure The transmembranous domains of the protein at the N- and C-terminus are shaded The five apyrase conserved regions (ACRs) are underlined and in bold The 10 cysteine...
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Báo cáo khoa học: Transport of taurocholate by mutants of negatively charged amino acids, cysteines, and threonines of the rat liver sodium-dependent taurocholate cotransporting polypeptide Ntcp docx
... amino acids and cysteines Tagging of Ntcp mutants by the FLAGÒ motif To determine whether the wild-type and the mutant proteins are expressed and located on the surface of the oocytes, the cDNA ... domains model), is involved in taurocholate transport of the human isoform [21] We therefore looked for the role of each of the eight cysteines of the rat Ntcp for taurocholate transport Finally, ... humans and rats begins by uptake across the basolateral membrane of hepatocytes via the high affinity, Fig Detection of the presence of Ntcp proteins in the cell membrane of X laevis oocytes by the...
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Báo cáo Y học: Purification and characterization of the thyrotropin-releasing hormone (TRH)-degrading serum enzyme and its identification as a product of liver origin doc
... whereas the serum enzyme and the liver enzyme belong to the groups of glycoproteins with a glycostructure of the complex type To substantiate the notion that the TRH-DEs from liver, serum and brain ... concentration of albumin and the activity of the TRH-DE in the culture medium increased in a correlative manner (Fig 2) Purification of the TRH-DEs from serum and liver The membrane-bound liver TRH-DE was ... activity of this enzyme in some species Nevertheless, these results support the notion that the serum TRH-DE, like most serum enzymes and proteins, is derived from the liver The decrease of the activity...
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Báo cáo khoa học: "Update and review of the multidisciplinary management of stage IV colorectal cancer with liver metastases" docx
... on the surgical aspects of the management of CLM and restrict discussion of chemotherapeutic agents to the context of their use in conjunction with surgical management Impact of Margin Status The ... limited extent of resection, assessment of tumor biology and response to chemotherapy Four other studies support the conclusions of the EORTC study supporting the use of chemotherapy as a bridge ... disease in which the management of these patients is complex These patients often receive chemotherapy given the extent of disease and this is valuable in patient selection because chemotherapy may...
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Diseases of the Liver and Biliary System - part 1 potx
... to the skin into the liver substance and extracted This is the quick part of the procedure The tip of the needle is now placed on sterile paper and some of the remaining saline flushed through the ... to a compartment of uncoupling of receptor and ligand (CURL) The receptor and ligand separate The receptor returns to sinusoidal plasma membrane and the ligand enters a lysosome and is degraded ... Anatomy of the biliary tract, Development of the liver and bile ducts, Anatomical abnormalities of the liver, Surface marking, Methods of examination, Hepatic morphology, Electron microscopy and...
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Diseases of the Liver and Biliary System - part 2 pot
... especially the hypothenar and thenar eminences and pulps of the fingers (fig 6.12) Islets of erythema may be found at the bases of the fingers The soles of the feet may be similarly affected The mottling ... diameter and is not obliterated by pressure Venous stars are seen on the dorsum of the foot, legs, back and on the lower border of the ribs Palmar erythema (liver palms) The hands are warm and the ... benzodiazepines and barbiturates (fig 7.9) The binding of any of these ligands opens a chloride channel and after the influx of chloride there is hyperpolarization of the postsynaptic membrane, and neuroinhibition...
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Diseases of the Liver and Biliary System - part 3 potx
... veins of the caval system Deviation of blood into these channels leads to varicosities in the submucous layer of the lower end of the oesophagus and fundus of the stomach (b) At the anus, the superior ... bypass the block and return blood towards the liver These enter the portal vein in the porta hepatis beyond the block They include the veins at the hilum, venae comitantes of the portal vein and ... by the union of the superior mesenteric vein and the splenic vein just posterior to the head of the pancreas at about the level of the second lumbar vertebra It extends slightly to the right of...
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Diseases of the Liver and Biliary System - part 4 docx
... one another to form septal bile ducts and so on until the two main hepatic ducts emerge from the right and left lobes of the liver at the porta hepatis Small bile ducts distal to the canals of Hering ... with other variations of the A(TA)nTAA allele have also shown elevated serum total bilirubin levels, including the alleles 5/6, 5/7 and 7/8 [5] In Asians and the Japanese, the frequency of the ... continuity with the space of Disse Disruption of the tight junction leads to free passage of solute and larger molecules into the canaliculus with loss of the osmotic gradient and cholestasis...
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Diseases of the Liver and Biliary System - part 5 pot
... serum IgG anti-HDV is found There may be a window period between the disappearance of one and the detection of the other Loss of IgM anti-HDV confirms the resolution of HDV infection, whereas persistence ... both as monotherapy, and, on the basis of recently completed large trials, in combination with ribavirin The cost and availability makes all these treatments out of reach of the millions of sufferers ... introspection by the patient Antiviral therapy The aim is to control infectivity, eradicate the virus and prevent the development of cirrhosis However, permanent loss of HBeAg and HBV DNA are unusual and...
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Diseases of the Liver and Biliary System - part 6 pps
... lipids synthesized in the liver itself The origin depends upon the dose of ethanol ingested and the lipid content of the diet After an acute, isolated ingestion of a large dose of ethanol the fatty ... redox state of the liver The hydrogen generated replaces fatty acid as a fuel and is followed by triglyceride accumulation and fatty liver The redox state of the liver changes, protein synthesis is ... related to the severity of the liver disease [72] The extent of the nutritional defect depends on the type of alcoholic, whether of low socioeconomic status where protein-calorie malnutrition often...
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Diseases of the Liver and Biliary System - part 8 ppt
... throughout the world except in New Zealand, Australia and some parts of the west Pacific The Borrelia multiply in the liver, invading liver cells and causing focal necrosis Just before the crisis the ... abscess in the left lobe of the liver may show a crescentic deformity of the lesser curve of the stomach US is the most useful (fig 29.7) CT shows the abscess with a somewhat irregular edge and low ... the liver parenchyma The lesions produced are single or multiple and of variable size The amoebic abscess is usually about the size of an orange The most frequent site is in the right lobe, often...
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Diseases of the Liver and Biliary System - part 9 pptx
... laterally over the gallbladder down to the duodenum, to the hepatic flexure of the colon and even to the right lobe of the liver, perhaps closing the foramen of Winslow In a milder form, a band of tissue ... anomaly the gallbladder lies under the left lobe of the liver, to the left of the falciform ligament This may be caused by the gallbladder migrating to a position under the left lobe of the liver ... lesions of the liver and bile ducts are increasingly being diagnosed This can be related to the improved methods of imaging the liver and bile ducts, and of liver biopsy Application of such methods...
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Diseases of the Liver and Biliary System - part 10 docx
... usually used The left lobe of the donor liver is excised and the right lobe anastomosed to the portal vein, inferior vena cava and aorta of the recipient The donor liver hypertrophies and the recipient’s ... depends on the clinical state of the patient and the staging of the tumour derived from radiological imaging Difficulties in removal arise because of the inaccessibility of the pancreas on the posterior ... which there is no acceptable, alternative therapy The patient and the family must understand the magnitude of the undertaking and be prepared to face the difficult early postoperative period and...
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báo cáo khoa học: "Liver metastasis originating from colorectal cancer with macroscopic portal vein tumor thrombosis: a case report and review of the literature" potx
... (arrow) and a perfusion defect in the entire right lobe Page of a c b Figure A) Macroscopic view of the resected liver including the metastatic liver tumor (arrowheads) and the tumor thrombus in the ... according to the TNM classification [15], and lymph node metastasis was found in most of the cases (12 of 14, 86%) In 12 of the 15 cases (80%), liver metastasis was accompanied by PVTT, and the liver ... tumor of approximately 25 mm in diameter consisting of two components: an apparently solid part and a cystic component The solid component of the tumor was enhanced in the early phase of the CTA and...
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Báo cáo y học: "Giant atypical carcinoid of the liver with vascular metastases and local sinusoidal invasion: a case report" potx
... structured a large part of the Discussion section AV was the primary resident involved in the radiologic studies for this case and handled the write-up of the radiologic portion of the manuscript WD ... to the liver and to compare these changes to those found in other carcinoids A complete and thorough autopsy is the only way to prove definitively that a carcinoid is truly primary to the liver, ... reports have shown the added benefits of systemic chemotherapy and hepatic artery chemoembolus injection [10] When given as the only form of therapy, chemotherapy drugs such as 5-FU and streptozocin...
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Báo cáo y học: "Undifferentiated liver sarcoma – rare entity: a case report and review of the literature" pps
... in the right lobe of the liver and part of the left lobe with ruptured capsule and the ruptured part adhered to pleura Tumor resection was performed and about 70% of the total liver was resected ... shows that, with the advent of modern surgical procedures and the use of pre and post operative chemotherapy, there has been an increase in the overall survival rate A recent review of published ... Reports 2008, 2:20 free of disease more than years after complete surgical excision of the tumor and chemotherapy.[3] The clinical features of ULS are often non-specific and may have varied presentation...
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Báo cáo y học: "Vasopressin in vasodilatory shock: hemodynamic stabilization at the cost of the liver and the kidney" doc
... infusion The study by Krejci and colleagues therefore raises the question of whether AVP compares favorably with catecholamines In a complementary investigation the same group compared the regional ... Krejci and colleagues confirm that the unrestricted use of even ‘low-dose’ AVP may result in ‘overconstriction’, in particular in the hepato-splanchnic region and the kidney Furthermore, the authors’ ... activation of the inducible isoform of nitric oxide synthase) probably did not assume major importance Finally, as the authors themselves acknowledge, although labelled ‘low dose’, the infusion...
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Báo cáo y học: " The influence of oxygen tension on the structure and function of isolated liver sinusoidal endothelial cells" potx
... Background The liver sinusoids are lined by endothelial cells that have a unique structure and function essential for hepatic and systemic homeostasis Much of our understanding of the biology of the ... IM and BS conceived of the study IM carried out most of the experimental work and the writing AW and DGL participated in the determination of fenestration parameters, statistical analysis and ... arteriole and the portal venule [10] In average, the oxygen content of hepatic blood is rather low (~55 mmHg) However, oxygen gradients normally exist between the periportal and the perivenous areas of...
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Báo cáo y học: "Mirror-Image Arachnoid Cysts in a Pair of Monozygotic Twins: A Case Report and Review of the Literature"
... case of MZ with mirror-imaging of AC in the literature In this case, we describe the second case of MZ with mirror-imaging of AC and discuss the possible clinical implications First, Helland and ... lack of systematic monitoring and follow-up Therefore, a large percentage of patients with AC are probably undiscovered Mirror images, on the other hand, are present in approximately 25% of MZ Therefore, ... consider that it is mandatory to monitor the counterpart of the symptomatic patient with AC as early as possible, irrespective of the absence of symptoms Conflict of Interest The authors have declared...
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Báo cáo y học: "Aplasia and Agenesis of the Frontal Sinus in Turkish Individuals: A Retrospective Study Using Dental Volumetric Tomograph"
... craniotomy because of the proximity of the sinus to the orbit and the anterior skull base [5] The frequency of bilateral absence of the frontal sinus has been reported in 3-4% to 10% of several populations ... reliability between observers and was 0.86 Fig Unilateral absence of the frontal sinus; on the right, the absence of the frontal sinus, and on the left, the limited aeration of the frontal sinus; axial ... sinuses, although there is only one frontal sinus ostium The size of the sinus and, therefore, its anatomic relationships also depend upon the extent of pneumatization [11] The extent of pneumatization...
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