regulation of nitric oxide synthase

Báo cáo khoa học: Binding and activation of nitric oxide synthase isozymes by calmodulin EF hand pairs potx

Ngày tải lên : 16/03/2014, 13:20

... (2001) Nitric oxide synthases: structure, function and inhibition Biochem J 357, 593–615 ´ Roman LJ, Martasek P & Masters BS (2002) Intrinsic and extrinsic modulation of nitric oxide synthase ... nitric- oxide synthase by a dual mechanism Activation of intra- and interdomain electron transfer J Biol Chem 269, 1179–1190 Chen PF, Tsai AL, Berka V & Wu KK (1996) Endothelial nitric- oxide synthase ... (1997) Calcium binding sites of calmodulin and electron transfer by neuronal nitric oxide synthase Biochemistry 36, 12337–12345 11 Ghosh DK & Salerno JC (2003) Nitric oxide synthases: domain structure...

13
336
0

Báo cáo khoa học: Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90 potx

Ngày tải lên : 23/03/2014, 07:20

... regulation of nitric oxide synthases and their allosteric regulators in heart and vessels of hypertensive rats Cardiovasc Res 57, 456–467 Thomas SR, Chen K & Keaney JF Jr (2002) Hydrogen peroxide ... Involvement of the proteasome in activation of endothelial nitric oxide synthase Life Sci 73, 2225–2236 Musial A & Eissa T (2001) Inducible nitric- oxide synthase is regulated by the proteasome degradation ... Ubiquitination of neuronal nitric- oxide synthase in vitro and in vivo J Biol Chem 275, 17407–17411 Hajimohammadreza I, Raser KJ, Nath R, Nadimpalli R, Scott M & Wang KKW (1997) Neuronal nitric oxide synthase...

12
338
0

Báo cáo khoa học: In vivo degradation of nitric oxide synthase (NOS) and heat shock protein 90 (HSP90) by calpain is modulated by the formation of a NOS–HSP90 heterocomplex pot

Ngày tải lên : 30/03/2014, 04:20

... University of Genoa References Kone BC, Kuncewicz T, Zhang W & Yu Z (2003) Protein interaction with nitric oxide synthases: controlling the right time, the right place, and the right amount of nitric oxide ... degradation of nitric oxide synthase: effect of inhibitors and role of HSP90-based chaperones J Pharmacol Exp Ther 304, 493–497 13 Govers R, de Bree P & Rabelink TJ (2003) Involvement of the proteasome ... (2002) Ubiquitination of inducible nitric oxide synthase is required for its degradation Proc Natl Acad Sci USA 99, 12315–12320 15 Musial A & Eissa T (2001) Inducible nitric- oxide synthase is regulated...

11
344
0

báo cáo hóa học: " Signaling pathways mediating a selective induction of nitric oxide synthase II by tumor necrosis factor alpha in nerve growth factor-responsive cells" pptx

Ngày tải lên : 19/06/2014, 22:20

... iNOS, inducible nitric oxide synthase; MAPK, mitogen activated protein kinase; NF-κB, nuclear factor kappa B; NGF, nerve growth factor; NO, nitric oxide; nNOS, neuronal nitric oxide synthase; NTR, ... Mechanism of selective motor neuronal death after exposure of spinal cord to glutamate: Involvement of glutamate induced nitric oxide in motor neuron toxicity and nonmotor neuron protection Annals of ... nitric oxide and dementia of the Alzheimer's type Brain Res Brain Res Rev 2001, 35:73-96 de la Monte SM, Lu BX, Sohn YK, Etienne D, Kraft J, Ganju N, Wands JR: Aberrant expression of nitric oxide...

13
447
0

Báo cáo khoa học: "Enhanced expression of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomyelitis" pdf

Ngày tải lên : 07/08/2014, 14:22

... of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomelitis 27 28 29 30 31 32 33 34 35 36 37 38 Induction of nitric oxide synthase activity in human astrocytes ... Fujimura, H and Yanagihara, T Nitric oxide via an inducible isoform of nitric oxide synthase is a possible factor to eliminate inflammatory cells from the central nervous system of mice with experimental ... Inhibition of nitric oxide synthase for treatment of experimental autoimmune encephalomyelitis J Immunol 1997, 158(6), 2940-2946 Buisson, A., Plotkine, M and Boulu, R G The neuroprotective effect of nitric...

7
290
0

Báo cáo khoa học: "Expression of nitric oxide synthase isoforms in the porcine ovary during follicular development" ppsx

Ngày tải lên : 07/08/2014, 18:21

... monoclonal anti-endothelial nitric oxide synthase (eNOS) antibody, rabbit anti-inducible nitric oxide synthase (iNOS) antisera, and rabbit anti-neuronal nitric oxide synthase (nNOS) antisera (all ... Immunohistochemical localization of neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) isoforms of nitric oxide synthase (NOS) in the ovaries of pigs The intensity of staining is indicated by ... Enhanced expression of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomyelitis J Vet Sci 2000, 1, 11-17 Knowles RG, Moncada S Nitric oxide synthases in mammals...

5
245
0

$Báo cáo y học: "Protective effects of total fraction of avocado/soybean unsaponifiables on the structural changes in experimental dog osteoarthritis: inhibition of nitric oxide synthase and matrix metalloproteinase-13" docx$

Báo cáo y học: "Protective effects of total fraction of avocado/soybean unsaponifiables on the structural changes in experimental dog osteoarthritis: inhibition of nitric oxide synthase and matrix metalloproteinase-13" docx

Ngày tải lên : 09/08/2014, 14:20

... Abramson SB: The expression and regulation of nitric oxide synthase in human osteoarthritis-affected chondrocytes: evidence for an inducible "neuronal-like" nitric oxide synthase J Exp Med 1995, 182:2097-2102 ... FY: Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients J Exp Med 1996, 184:1519-1524 42 Stefanovic-Racic M, Stadler J, Evans CH: Nitric oxide and arthritis ... effect of ASU on clinical symptoms of knee and hip OA, with a carryover effect that persists after termination of treatment [10-12] The primary aim of the present study was to explore the effects of...

9
547
0

Báo cáo y học: "Time course of nitric oxide synthases, nitrosative stress, and poly(ADP ribosylation) in an ovine sepsis model" pot

Ngày tải lên : 13/08/2014, 21:20

... endothelial nitric oxide synthase; FiO2: fraction of inspired oxygen; GAPDH: glyceraldehyde 3-phosphate dehydrogenase; IL: interleukin; iNOS: inducible nitric oxide synthase; nNOS: neuronal nitric oxide ... Stephen J, Cepinskas G: Role of endothelial nitric oxide synthase- derived nitric oxide in activation and dysfunction of cerebrovascular endothelial cells during early onsets of sepsis Am J Physiol ... constitutively express neural nitric oxide synthase mRNA Nitric Oxide 1998, 2:203-212 29 Saini R, Patel S, Saluja R, Sahasrabuddhe AA, Singh MP, Habib S, Bajpai VK, Dikshit M: Nitric oxide synthase localization...

10
247
0

Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of ﬂavoproteins: electron transfer through the nitric oxide synthase ﬂavoprotein domain pdf

Ngày tải lên : 18/02/2014, 11:20

... calcium-regulated isoforms of nitric oxide synthase J Biol Chem 272, 29769–29777 Daff S, Sagami I & Shimizu T (1999) The 42-amino acid insert in the FMN domain of neuronal nitricoxide synthase exerts ... Function of the reductase unit of nitric oxide synthase: catalytic model Nitric Oxide 19, S50 Presta A, Weber-Main AM, Stankovich MT & Stuehr D (1998) Comparative effects of substrates and pterin cofactor ... activity of endothelial nitric oxide synthase Proc Natl Acad Sci USA 104, 9254–9259 Stuehr DJ, Wei CC, Santolini J, Wang Z, Aoyagi M & Getzoff ED (2004) Radical reactions of nitric oxide synthases...

16
639
0

Tài liệu Báo cáo khoa học: Polarized distribution of inducible nitric oxide synthase regulates activity in intestinal epithelial cells pdf

Ngày tải lên : 19/02/2014, 16:20

... subcellular distribution of the human inducible nitric oxide synthase in an intestinal cell line: evidence for post-translational regulation In The Biology of Nitric Oxide Part 7, (Moncada S, ... assembly of inducible NO synthase into an active dimer J Biol Chem 274, 930–938 Kuncewicz T, Balakrishnan P, Snuggs MB & Kone BC (2001) Speciﬁc association of nitric oxide synthase- 2 with Rac isoforms ... Decreased activity of inducible nitric oxide synthase type and modulation of the expression of glutathione S-transferase alpha, bcl-2, and metallothioneins during the differentiation of CaCo-2 cells...

10
457
0

Báo cáo khoa học: Relationship between the structure of guanidines and N-hydroxyguanidines, their binding to inducible nitric oxide synthase (iNOS) and their iNOS-catalysed oxidation to NO pptx

Ngày tải lên : 16/03/2014, 22:20

... substrates for nitric oxide synthases Bioorg Med Chem 10, 3049–3055 Jia Q, Cai T, Huang M, Li H, Xian M, Poulos TL & Wang PG (2003) Isoform-selective substrates of nitric oxide synthase J Med ... binding of arginine analogs to nitric oxide synthases Nitric Oxide Biol Chem 5, 442–452 13 Ghosh S, Wolan D, Adak S, Crane BR, Kwon NS, Tainer JA, Getzoff ED & Stuehr DJ (1999) Mutational analysis of ... in the biosynthesis of nitric oxide from l-arginine J Biol Chem 266, 6259–6263 Klatt P, Schmidt K, Uray G & Mayer B (1993) Multiple catalytic functions of brain nitric oxide synthase Biochemical...

12
507
0

Báo cáo khoa học: Rapamycin inhibits lipopolysaccharide induction of granulocyte-colony stimulating factor and inducible nitric oxide synthase expression in macrophages by reducing the levels of octamer-binding factor-2 doc

Ngày tải lên : 22/03/2014, 17:20

... (2003) Regulation of the expression of inducible nitric oxide synthase Biol Chem 384, 1343–1364 10 Kleinert H, Pautz A, Linker K & Schwarz PM (2004) Regulation of the expression of inducible nitric ... (2000) Differential anti-inﬂammatory effects of immunosuppressive drugs: cyclosporin, rapamycin and FK-506 on inducible nitric oxide synthase, nitric oxide, cyclooxygenase-2 and PGE2 production ... lipopolysaccharidestimulated nitric oxide production in macrophages via interferon-beta J Leukoc Biol 67, 405–414 Xie Q (1997) A novel lipopolysaccharide-response element contributes to induction of nitric oxide synthase...

12
376
0

Báo cáo khoa học: Cupiennin 1a, an antimicrobial peptide from the venom of the neotropical wandering spider Cupiennius salei, also inhibits the formation of nitric oxide by neuronal nitric oxide synthase pptx

Ngày tải lên : 23/03/2014, 09:21

... when it binds to the CaM-binding domain of endothelial nitric oxide synthase (eNOS) [33] The second example is when the C-terminal lobe of Ca2+-CaM binds part of the target peptide This is shown ... that of Ca2+-CaM [10,11,25,26], and therefore adversely affects binding of CaM to the Ca2+-CaM-binding domain of nNOS CaM is not only essential for the operation of nNOS and the other NOS isoforms, ... formation of NO by neuronal nitric oxide synthase (nNOS) [10] These particular amphibian peptides (e.g the caerins and splendipherin [11]), are basic and hinged, and inhibit the operation of nNOS...

7
366
0

Báo cáo khoa học: Thermodynamic and kinetic analysis of the isolated FAD domain of rat neuronal nitric oxide synthase altered in the region of the FAD shielding residue Phe1395 docx

Ngày tải lên : 30/03/2014, 14:20

... FAD isoalloxazine ring nNOS, rat neuronal nitric oxide synthase; eNOS, rat endothelial nitric oxide synthase; iNOS, rat inducible nitric oxide synthase; CPR, human cytochrome P450 reductase; NR1, ... analysis of the ﬂavin cofactors of neuronal nitric oxide synthase Biochemistry 38, 16413–16418 Wolthers, K.R., Basran, J., Munro, A.W & Scrutton, N.S (2003) Molecular dissection of human methionine synthase ... Nitric Oxide Synthases Annu Rev Pharmacol Toxicol 37, 339–359 Marletta, M.A (1993) Nitric- oxide synthase structure and mechanism J Biol Chem 268, 12231–12234 Bredt, D.S & Snyder, S.H (1994) Nitric...

13
364
0

Báo cáo Y học: Amphibian peptides that inhibit neuronal nitric oxide synthase The isolation of lesueurin from the skin secretion of the Australian Stony Creek Frog Litoria lesueuri docx

Ngày tải lên : 31/03/2014, 15:20

... three-dimensional structures of certain domains of nitric oxide synthase isoforms are known [53±57], we are not aware of the three-dimensional structure of the calmodulin binding sites of any isoform being reported ... comparison of the calmodulinbinding domains of nitric oxide synthases J.Biol Chem 271, 6435±6440 43 Lee, S.J & Stull, J.T (1998) Calmodulin-dependent regulation of inducible and neuronal nitric oxide synthase ... peptides, unlike the majority of the other members of the genus Litoria Instead, it produces a neuropeptide that inhibits the formation of nitric oxide by neuronal nitric oxide synthase (nNOS) We next...

10
463
0

Báo cáo khoa học: "Immunohistochemical study of constitutive neuronal and inducible nitric oxide synthase in the central nervous system of goat with natural listeriosis" potx

Ngày tải lên : 07/08/2014, 14:23

... constitutively express neuronal nitric oxide synthase mRNA Nitric Oxide 1998, 2, 203-212 Hooper, D.C., Ohnishi, S.T., Kean, R., Numagami, Y., Dietzschold, B and Koprowski, H Local nitric oxide production in ... expression of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomyelitis J Vet Sci., 2000, 1, 11-17 11 Moncada, S., Palmer, R.M.J and Higgs, E.A Nitric oxide: physiology, ... Magnification A and B, ×66 C and D, ×132 Immunohistochmical study of nitric oxide synthase in the central nervous system of goat Enhanced expression of nNOS and iNOS in L monocytogenes-infected brain At...

4
437
0

Báo cáo khoa học: "Increased expression of neuronal nitric oxide synthase in astrocytes and macrophages in the spinal cord of Lewis rats with autoimmune encephalomyelitis" pps

Ngày tải lên : 07/08/2014, 15:20

5
363
0

Báo cáo khoa học: " Effects of L-NAME, a non-specific nitric oxide synthase inhibitor, on AlCl3-induced toxicity in the rat forebrain cortex" doc

Ngày tải lên : 07/08/2014, 23:22

... Ivana D Stevanović et al 18 19 20 21 22 23 24 25 26 27 28 29 reduces expression of neuronal nitric oxide synthase and of soluble guanylate cyclase and impairs glutamatergic neurotransmission in rat ... shaped, and is still refining, the nature of oxidative signaling in terms of regulating the milieu of inflammatory mediators, ostensibly via the modulation of oxygen- and redox-responsive transcription ... factors Hence, they are termed redox(y)-sensitive cofactors [12] Also, anti-oxidative defense includes both of the superoxide dismutase (SOD)-isoforms (Mn-SOD, Cu/ZnSOD), which are induced to prevent...

8
288
0

Báo cáo y học: "Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1" pdf

Ngày tải lên : 09/08/2014, 06:22

... expression profile of aggrecan mimicked that of type II collagen but with a slight delay of a couple of days The decline in expression of both chondrocyte markers coincided with the onset of late-stage ... (JAK)2 inhibition blocks leptin/IL-1-induced nitric oxide (NO) production and nitric oxide synthase (NOS) type II protein expression expression Effect of tyrphostin AG490 and Tkip on NO production ... Figure Involvement of (NOS) oxide synthase phosphatidylinositol 3-kinase (PI3K), mitogen-activated protein kinase kinase (MEK)-1 and p38-kinase in leptin/IL-1-induced nitric oxide synthase (NOS)...

11
503
0

Báo cáo y học: "Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes" pps

Ngày tải lên : 09/08/2014, 06:23

... Abramson SB: The expression and regulation of nitric oxide synthase in human osteoarthritis-affected chondrocytes: evidence for up regulated neuronal nitric oxide synthase J Exp Med 1995, 182:2097-102 ... induction of nitric oxide synthase by interleukin-1β in rat glomerular mesangial cells J Biol Chem 1999, 274:36200-36206 69 Taylor BS, Geller DA: Molecular regulation of the human inducible nitric oxide ... expression in bovine articular chondrocytes Nitric Oxide 2002, 6:35-44 66 LaPointe MC, Isenovic E: Interleukin-1β regulation of inducible nitric oxide synthase and cyclooxygenase-2 involves the...

12
388
0