... prosthesis inserted into the portal vein and the inferior vena cava of thein vivo rabbit model Figure Diagram of silastic H-shaped prosthesis inserted into the portal vein and the inferior vena ... relating the readings to the wet weight of the liver, determined at the end of each experiment The "buffering capacity" of the HA was expressed in % as: [Increase in HA flow / Decrease in PV flow] ... changes inbloodflow vs dose of drug injected were then constructed Calculations Blood flows were recorded on the flowmeters in ml min-1 and subsequently recalculated in ml min-1 100 g-1 by relating...
... the specimens were obtained from thelungThe remaining rats (n = 10) were sacrificed after monitorization for five days and thelung was analyzed patologically on the fifth day The sampled lung ... on the fifth day were analyzed inthe histopathological evaluation Masses of hemolyzed clot (blood- fibrin masses) were observed inthe areas in which Ankaferd had been applied inthe lungs of intraoperatively ... Technique All the rats underwent left anterior thoracotomy An injury mm in length and 2mm in depth was created inthe left lung parenchyma using a scalpel Inthe control group (Group I), no interventions...
... during lung lavages and during the following two hours of mechanical ventilation The administration of epinephrine and the infusion of Ringer's solution during the rest of the experiment were then ... Pmean settings in a lung lavage model Thelung lavage model affects particularly the lung, whereas other organs are not involved, and organ bloodflow autoregulation is theoretically intact In this ... end-diastolic pressure, and intracranial pressure during lung recruitment in both ventilatory modes The cerebral blood flow, myocardial blood flow, renal blood flow, and bloodflow of the jejunum, however,...
... reported findings and interpretations APV was instrumental inthe coordination of the study and the performance of data gathering He carried out the cytokine ELISAs He was also intimately involved ... respectively), indicating that inflammation is more pronounced inthe pulmonary compartment For the other cytokine levels, the mean ratio had a value of around 1, indicating that the level of the cytokines ... gathering and analysis He read the final version of the manuscript and agrees with all reported findings and interpretations JJH was instrumental in data gathering and analysis He read the final...
... “strain-hardening” Many materials including polymer melts and solutions thus exhibit shearthinning in simple shear and strain-hardening in uniaxial extension Except inthe limit of vanishingly ... –104 Spreading and coating Rubbing 104 –105 Milling pigments in fluid bases High speed coating Lubrication 103 –105 105 –106 103 –107 Paints, printing inks Application Painting and coating, Toilet ... frictional force inthe fluid For an incompressible Newtonian fluid in laminar flow, the resulting shear stress is equal to the product of the shear rate and the viscosity of the fluid medium In this simple...
... used to detect the area with the highest bloodflow within the corpus luteum Bloodflow was identified inthe peripheral area of the corpus luteum [4] The pulsed Doppler gate was then placed on ... calculating the resistance index (RI), which is defined as the difference between maximal systolic bloodflow (S) and minimal diastolic flow (D) divided by the peak systolic flow (S-D/S) Bloodflow ... to know whether luteal bloodflow is regulated by LH Therefore, the present study was undertaken to examine luteal bloodflowinthe patient undergoing GnRHa long protocol Methods The project...
... leaves, inthe lower part of the branches produced inthe same year Staminate inflorescences are initiated in late spring, flowers develop in early summer and meiosis occurs inthe following spring, ... 1980) The characteris- rescences tics of male and female flowers marized below are sum- Male flowers are grouped in catkins which inthe axils of either the inner bud scales or the first leaves, in ... Bonnet-Masimbert (1978) has hypothesized that their initiation may occur in late spring, when the staminate inflorescences develop Female flowers develop in late winter or early spring (Bonnet-Masimbert,...
... Urinary incontinence Urinary incontinence (UI) is defined as the involuntary loss of urine, of sufficient severity to be a health Cancer inthe older person Complete the screen by filling inthe ... at baseline, anemia incidence was 63% in those undergoing chemotherapy alone, 42% in those receiving a combination of chemotherapy and radiotherapy, and 20% in those treated with radiotherapy ... asking the patient to raise arms straight up inthe air, behind the neck, and behind the back [55] A timed six-meter walk or the distance walked in six minutes can be used to provide objective information...
... point the HSC numbers dramatically fell in D2 mice while they continued to rise inthe B6 mice Thus, we surmised that the aging of the stem cells in these two strains differed according to their ... answers For instance, does aging begin at birth, at which point development has culminated in an independently functioning individual, or does it begin at puberty, when the individual has attained reproductive ... lifespan determination in these two strains Congenic mice were then generated where we crossed the QTLcontaining interval from the D2 strain onto a B6 background (B6.D2 Chr 2) to test the mapping data...
... A/Taiwan/1/86-induced viral cytotoxicity in vitro Interestingly and unexpectedly, the IgA responses to the H3N2 vaccine strain were higher inthe older than inthe younger participants [16] Therefore, the ... competing schools of thought on the dominant mechanism leading to the age-related decline in antibody production in response to foreign antigens These lines of thinking have attributed the age-related ... called “cross-wiring.” There are several factors explaining the underlying mechanism of the age-related increase in autoantibody, which are related to the age-related decline inthe antibody response...
... is destined for the hemoglobin in developing erythrocytes inthe bone marrow Inthe absence of bleeding, iron losses from desquamation of intestinal epithelia and skin are relatively minor See ... Experiments in mice lacking IL-6 show that other cytokines, including IL-1, may contribute to hepcidin induction during in ammation, but it is not certain whether the specific hepcidin-stimulatory cytokines ... utilization Iron is excreted by shedding of intestinal and skin cells, and through minor blood loss inthe intestine In principle, the iron content of shed epithelial cells could be subject to regulation...
... erythropoietin insufficiency in older individuals [20] (Fig 15.2) When the circulating levels of erythropoietin were plotted against the levels of hemoglobin and the levels of in ammatory cytokines one ... ferroportin, a protein responsible for carrying the iron from the gastrointestinal tract into the circulation Incidence and prevalence of cobalamin deficiency increase with age [23,24], due to inability ... unexplained; CRP, C-reactive protein; EPO, erythropoietin; CrCl, creatinine clearance; WNL, within normal limits Other abbreviations as in Table 16.1 deficient in iron, either alone or in combination...
... MDS inthe first-line setting [103,104] Fludarabine with cytarabine inthe relapsed/refractory setting has a reported CR rate of 36% [105] Non-cytarabine regimens have also been investigated inthe ... remains investigational However, because of the high prevalence of the MDR1 phenotype inthe elderly population, there is continued investigation into the use of more potent and specific inhibitors ... Pgp overexpression inthe elderly supports the finding that conventional induction therapy inthe elderly is less efficacious than in younger adults Therapeutic strategies to inhibit Pgp cellular...
... telangiectasia Retinoic acid derivatives, including isotretinoin, etretinate, and acitretin, have demonstrated marginal potency against CTCL as monotherapy; however, they have been used mostly in combination ... protein and rapidly improve the clinical situation In this setting chemotherapy should be instituted soon after plasmapheresis to control the disease over the longer term Marginal zone lymphomas There ... (DAB389IL-2, Ontak, DD) is a cytotoxic fusion protein combining the enzymatically active moiety of the diphtheria toxin to the receptor-binding domain of IL-2 It is currently used for patients with...
... for maintenance therapy with fludarabine? Is there an optimal combination – and sequencing – for administering fludarabine and an alkylating agent as combined therapy? The National Cancer Institute ... for the increase in circulating CD34ϩ cells in idiopathic myelofibrosis [28] Interestingly, there is also an increase in circulating endothelial precursor cells that appears to precede the increase ... fusion protein that has been produced by recombinant DNA technology, in which the receptor-binding domain of diphtheria toxin is replaced by the sequences of human interleukin [113] These compounds...
... fibrinolysis by removing the C-terminal lysine and arginine residues from fibrin, thereby decreasing plasminogen on its surface [70] A single nucleotide polymorphism inthe coding region of the ... management of the vitamin K antagonists Initiation and maintenance dosing Following the administration of warfarin, an initial effect on the prothrombin time (PT) usually occurs within the first two ... described inthe TAFI gene, nine in promoter region, two inthe 3Ј untranslated region, and three inthe coding region These polymorphisms are in strong linkage disequilibrium and form four main haplotypes...
... decreased pain and regional osteoporotic findings inthe foot or ankle Also, since the discontinuation of the bisphosphonate treatment, our patients have not complained of bone pain, and normal ... treatment, including physiotherapy and NSAID administration, was initiated in another clinic, the pain in his ankle progressively worsened and he demonstrated gait disturbance A physical examination ... nine months earlier, he began to feel severe right foot pain without any trigger events Although treatment, including physiotherapy and NSAID administration, was initiated in another clinic, the...
... ASB assisted in acquiring the data, drafting the manuscript, and interpreting the results All authors have read and approved the final manuscript 12 Acknowledgements The authors thank the staff ... post-bronchodilator lung function measurements at these visits The rationale for using these visits was that the inclusion criteria limited the range of lung disease severity at baseline to mild and ... body mass index and randomization cohort were included inthe adjusted models Results There were a total of 5,887 participants intheLung Health Study, of whom 721 died by the end of the follow-up...
... Grx1, in being able to be excreted into the airways where it can participate inthe maintenance of GSH homeostasis GSH levels are increased inthe BAL fluid representing epithelial lining fluid ... incubating the sections in 3% hydrogen peroxide in absolute methanol for 15 minutes The sections were incubated with the primary antibody for GSTO1-1 using a dilution of 1:200 The immunostaining ... laboratory and others [17,26,27] β-actin has shown high individual variability, especially in tissue samples from the diseased lung Instead of using β-actin as a loading control, the protein concentration...