... informed consent from parents and patients (where appropriate for age) before entering patients into the study List of Abbreviations ALL: Acute lymphoblastic leukaemia; CNS: Centralnervous system; ... without cranial radiotherapy of children receiving intensified chemotherapy for acute lymphoblastic leukaemia: results of the risk-stratified randomized centralnervoussystem treatment trial ... 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 methotrexate (33.6 g/m(2)) as centralnervoussystem preventive therapyfor childhood acute lymphoblastic leukemia: results of National Cancer Institute/Children’s...
... radiation-induced centralnervoussystem toxicity: a role for amifostine? Anticancer Res 2004, 24:3803-3810 Publish with Bio Med Central and every scientist can read your work free of charge "BioMed Central ... the centralnervous system: an interpretation of target cell responses Br J Cancer 1986, 53(Suppl 7):207-217 Schultheiss TE, Kun LE, Ang KK, Stephens LC: Radiation response of the centralnervous ... Pintilie M, Wong CS: Hypoxia and hypoxiainducible factor-1 target genes in centralnervoussystem radiation injury: a role for vascular endothelial growth factor Clin Cancer Res 2004, 10:3342-3353...
... Corey L, Driscoll T, Cornely OA, Schuler U, Lutsar I, Troke P, Thiel E: Improved outcome in centralnervoussystem aspergillosis, using voriconazole treatment Blood 2005, 106:2641-2645 Walsh TJ, Anaissie ... this article as: Zhang M, et al.: Invasive pulmonary and centralnervoussystem aspergillosis following slops aspiration in a trauma patient Critical Care 2010, 14:442 ... Combination therapy of disseminated coccidioidomycosis with caspofungin and fluconazole BMC Infect Dis 2006, 6:26 doi:10.1186/cc9228 Cite this article as: Zhang M, et al.: Invasive pulmonary and central...
... SURFACE MODIFICATION OF BACULOVIRUS DERIVED VECTORS FOR IMPROVED GENE DELIVERY TO THE CENTRALNERVOUSSYSTEM YANG YI (B Eng.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY GRADUATE PROGRAMME ... vectors in order to achieve improved gene delivery to the CentralNervousSystem There are many important requirements for an ideal gene delivery system, including feasible vector production procedure, ... vectors for gene delivery to the nervoussystem has been limited by their ability to transfer genes only to dividing cells, although they are well suited for on-site delivery to neural precursors for...
... Conclusion 109 Chapter References 112 VIII SUMMARY Gene therapy is a promising approach for the treatment of neurological disorders in the centralnervoussystem (CNS) Because of the complex structure ... used for gene therapy applications, and were rarely used for 12 Chapter Introduction gene delivery to the CNS because of their poor in vivo performance Non-viral and viral vectors are therefore ... small capacity for foreign genes Therefore, it would be very desirable to incorporate the elements responsible for integration of AAV to other viral vectors to improve their performance by prolonging...
... 87.7 81.2 76.7 69.5 63.7 60.6 Other CentralNervousSystem National Cancer Institute 205 SEER Survival Monograph Chapter 25 Cancer of the Brain and NervousSystem Table 25.3: Cancer of the Brain: ... Specified 210 SEER Survival Monograph Chapter 25 Cancer of the Brain and NervousSystem Table 25.7: Cancer of the Other CentralNervous System: Distributions and 5-Year Relative Survival Rates (%) by ... Institute 211 SEER Survival Monograph Chapter 25 Cancer of the Brain and NervousSystem Table 25.9: Cancer of the Other CentralNervousSystem Cancer: 1-, 2-, 3-, 5-, 8-, & 10-Year Relative Survival Rates...
... (coral, jellyfish, sea anemones), which possess the most primitive form of nervous system, suggesting that the archetype nervous systems may have relied on amidated peptides [5] The C-terminal a-amidation ... cycling was performed with 40 cycles of the following step program: 94 °C for min, 43.5 °C for (primer annealing), and 72 °C for (primer extension) Final primer extension was made at 72 °C for The PCR ... kb, as found for higher vertebrate PAMs Therefore, PHM and PAL are coded for by different genes in the planarians and only later in the evolution these genes appear to have fused, forming a single...
... archived on PubMed Central yours — you keep the copyright BioMedcentral Submit your manuscript here: http://www.biomedcentral.com/info/publishing_adv.asp Page 13 of 13 (page number not for citation ... though the chemokine network is notorious for its redundancy and receptor promiscuity in vitro, studies in rodent models for MS have utilized techniques for genomic deletion of chemokines [24], ... time-points at which subsequent kinetic analyses were performed Rats (n = 3/time-point) which conformed in the clinical score curve were chosen for histopathology and evaluation of CCR1, CCR2 and...
... Treatment of CentralNervousSystem Degenerative Disorders) These columnar ensembles serve to interconnect nested distributed systems in which sensory associations are rapidly modifiable as information ... the autonomic nervous system, and they may integrate somatic and vegetative functions, including those of the cardiovascular and gastrointestinal systems Limbic System The "limbic system" is an ... pallidus, and lentiform nucleus) form an essential regulatory segment of the so-called extrapyramidal motor system This system complements the function of the pyramidal (or voluntary) motor system Damage...
... anticonvulsant therapy, as well as the tumor itself children with leukemia receive chemotherapy as a preventative measure (CNS prophylaxis) and, therefore, have no specific risk factors for cognitive ... however, chemotherapy in increasing doses has become routine Very high dose chemotherapy, requiring bone marrow transplantation or peripheral stem cell support, is now standard therapyfor children ... RF, Holland JC, Tull R, Berman A, Brecher ML, Harris M, Glickman AS, Forman E, et al.: Effects of different forms of centralnervous prophylaxis on neuropsychologic function in childhood leukemia...
... outcome of many forms of cancer treatment In contrast, there has been no comparable level of analysis for most other organ systems compromised by cancer treatments One of the tissues for which adverse ... the centralnervoussystem (CNS) Although it has long been appreciated that targeted irradiation of the CNS may be associated with neurological damage, it has become increasingly clear that systemic ... chemotherapy for non-CNS cancers also can have a wide range of undesirable effects This has been perhaps most extensively studied in the context of breast cancer (for examples, see [1-13]) For...
... Dietrich J, Luebke A, Mayer-Pröschel M, Noble M: Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the centralnervoussystem J Biol 2008, 7:12 Lee GD, Longo DL, ... following cancer chemotherapy Clin Cancer Res 2006, 12:198-205 Moleski M: Neuropsychological, neuroanatomical, and neurophysi ological consequences of CNS chemotherapy for acute lym phoblastic ... after postoperative chemotherapy for breast carcinoma Cancer 1999, 85:640-650 Castellon SA, Ganz PA, Bower JE, Petersen L, Abraham L, Greendale GA: Neurocognitive performance in breast cancer...
... autoimmune disease of the centralnervoussystem Proc Natl Acad Sci U.S.A 1995, 92, 5312-5316 Johnson, G.C., Fales, W.H., Maddox, C.W and RamosVara, J.A Evaluation of laboratory test for confirming the ... Magnification A and B, ×66 C and D, ×132 Immunohistochmical study of nitric oxide synthase in the centralnervoussystem of goat Enhanced expression of nNOS and iNOS in L monocytogenes-infected brain At ... and the primary antisera were reacted for 60 min, followed by biotinylated antisera (Zymed) for 15 minutes and [strept]avidin- biotin peroxidase (Zymed) for 15 minutes Staining was done using...
... Primary centralnervoussystem vasculitis: analysis of 101 patients Ann Neurol 2007, 62:442-451 MacLaren K, Gillespie J, Shrestha S, Neary D, Ballardie FW: Primary angiitis of the centralnervous system: ... Angiitis of the CentralNervous System: a Case Report and Review CNS Spectrums 2008, 13:209-213 Page of 10 Ozawa T, Sasaki O, Sorimachi T, Tanaka R: Primary angiitis of the centralnervous system: report ... the centralnervous system: initial and follow-up MR features Neuroradiology 2009, 51:651-659 12 Ay H, Sahin G, Saatci I, Söylemezoğlu F, Saribaş O: Primary Angiitis of the CentralNervous System...
... centralnervoussystem Archives of neurology 2008, 65(1):65-70 Hagberg L, Dotevall L, Norkrans G, Larsson M, Wachter H, Fuchs D: Cerebrospinal fluid neopterin concentrations in centralnervoussystem ... Hagberg et al., Cerebrospinal fluid neopterin: an informative biomarker of centralnervoussystem immune activation in HIV-1 infection AIDS Research and Therapy 2010, 7:15 ... intraquartile range for each group Additionally, no correlation was found using the older CPE score system (not shown) [41] Hagberg et al AIDS Research and Therapy 2010, 7:15 http://www.aidsrestherapy.com/content/7/1/15...
... Primary centralnervoussystem lymphoma: radiologic-pathologic correlation RadioGraphics 17, 1497–1526 (1997) DE Hobson, BA Anderson, I Carr, M West, Primary lymphoma of the centralnervous system: ... primary malignant lymphoma of the centralnervoussystem Surg Neurol 26, 79–84 (1986) doi:10.1016/0090-3019(86)90068-6 NA Mohile, LE Abrey, Primary centralnervoussystem lymphoma Neurol Clin 25, ... Primary centralnervoussystem lymphoma presenting as a pure third ventricular lesion: a case report Journal of Medical Case Reports 2011 5:213 Submit your next manuscript to BioMed Central and...
... wish to thank Jerry H Houl for his assistance in cryocutting, to CitoViva for performing the hyperspectral imaging, to Ke Wang for the XPS analysis, and to Carlos Sanchez for his assistance in cockroach ... nAuNPs treated brains were scanned for comparison Figure 5a shows the results for the control sample and Figure 5b for the nAuNPs treated brain The binding energy for gold is at 85 eV The high signal-to-noise ... nanoparticle interaction with the nervoussystem during signal transfer i.e during a nerve impulse Methods A new method to introduce nanoparticles into the nervoussystem (NS) of Blaberus discoidalis...
... thrombosis, post-traumatic stress disorder, insomnia, chronic pain, and obstructive sleep apnea For these disorders his medication regimen included metformin, budesonide and formoterol fumarate ... cervical spinal stenosis, he was scheduled for a C3-C7 laminoplasty for spondylosis and myelopathy Our patient’s past medical history was significant for non-insulin dependent diabetes mellitus, ... is crucial for the clinician to remember cases such as this one if faced with an unusual postoperative recovery phase Consent Written informed consent was obtained from the patient for publication...
... virus elements in the centralnervoussystem of SJL/J and C57BL/6 mice after infection Expression Expression of Toll-like receptors for bacterial elements in the centralnervoussystem of SJL/J and ... after infection with Expression of Toll-like receptors for viral Expression of Toll-like receptors for viral elements in the centralnervoussystem of SJL/J and C57BL/6 mice after infection with ... number not for citation purposes) Virology Journal 2008, 5:154 http://www.virologyj.com/content/5/1/154 Figure Theiler's3murine encephalomyelitis virus elements in the centralnervoussystem of...