regeneration repair and fibrosis after liver injury

Báo cáo y học: " Epithelial cell senescence impairs repair process and exacerbates inflammation after airway injury" doc

... enzyme [11-14] Repair of the airway epithelium after NA injury is accomplished in several overlapping stages In mice, the proliferative response peaks to days after NA injury and is followed ... processes and exacerbates inflammation after airway injury, and presumably contributes to pathological alterations in the airways of COPD patients Methods Page of 18 maximal to days after exposure ... sacrificed on day 28, and lung tissue sections were double immunostained for (A) CC10 (green) and b-tubulin (brown), (B) CC10 (green) and Ki-67 (brown), and (E) BrdU (green) and Ki-67 (brown) Arrowheads...

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Báo cáo y học: "Serine/threonine kinase-protein kinase B and extracellular signal-regulated kinase regulate ventilator-induced pulmonary fibrosis after bleomycin-induced acute lung injury: a prospective, controlled animal experiment" pptx

Danh mục: Báo cáo khoa học

... (Figure 1b) and performed Masson's trichrome staining and fibrosis scoring (Figure 2a,b,c,g) Five days after bleomycin treatment, an increase of peribronchiolar fibrosis and of parenchymal fibrosis ... SB203580, and Akt-deficient mice reduced stretch-induced microvascular leak, lung fibrosis, and chemokine production After days of reduced stretch-induced microvascular leak, lung fibrosis, and chemokine ... epithelium and fibroblasts in the interstitium, and the phosphorylation of Akt and ERK1/2 were significantly reduced after using Akt-deficient mice and pharmacological inhibition with PD98059 and SB203580...

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Báo cáo y học: "Expression of AFP and Rev-Erb A/Rev-Erb B and N-CoR in fetal rat liver, liver injury and liver regeneration" doc

Danh mục: Báo cáo khoa học

... hepatocarcinogenesis and non- Figure liverof AFP gene and Rev-Erb A, Rev-Erb B and NCoR in Expression regeneration without 2-AAF treatment Expression of AFP gene and Rev-Erb A, Rev-Erb B and N-CoR in liver regeneration ... for studying liver regeneration after PH Two series were performed for each model The animals were kept with food and water, ad libitum For each model of liver regeneration and liver injury, two ... analyses, in rat liver after CCl4 treatment, after PH with and without 2AAF treatment and in the fetal liver Additionally, we studied AFP gene expression in the liver of rats after intramuscular...

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Báo cáo y học: "Severe endothelial injury and subsequent repair in patients after successful" ppsx

Danh mục: Báo cáo khoa học

... CECs, EMPs and vWF, as well as markers of endothelial repair (EPCs) in peripheral blood of patients after successful CPR Materials and methods Patients and blood sampling protocol After the approval ... atherosclerotic risk factors, and a higher cardiovascular morbidity and mortality [23] In the present study, we hypothesize that endothelial injury takes place during and after CPR, which in turn ... patients after successful CPR, and in a follow-up study, of a subsequent endothelial regeneration In summary, we found a rapid and severe increase in CECs directly after CPR and a delayed increase in...

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Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke docx

Danh mục: Báo cáo khoa học

... angiogenesis and brain recovery (Fig 3) Because similar signals and substrates are involved, one will have to be very careful in terms of understanding how and when these injury- into -repair transitions ... JNK in CNS disease and repair [64] JNK signaling is involved in neuronal precursor cell migration, microtubule assembly and axonal guidance during brain development After injury, this signal ... cells is indeed triggered after ischemic events [44,46] In mice, endothelial proliferation may begin within a day after ischemia and persist for up to several weeks thereafter [47,48] Genes correlated...

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awareness of deficit after brain injury clinical and theoretical issues jan 1991

Danh mục: Vật lý

... Awareness of Deficit After Brain Injury This page intentionally left blank Awareness of Deficit After Brain Injury Clinical and Theoretical Issues Edited by GEORGE P PRIGATANO ... Dementia and Schizophrenia 84 SUSAN M MCGLYNN AND ALFRED W KASZNIAK Disturbances of Self-Awareness of Deficit After Traumatic Brain Injury 111 GEORGE P PRIGATANO Unawareness of Deficit and Unawareness ... associated with altered awareness after brain injury Finally, the last chapter considers the theoretical and clinical reasons forms of unawareness of deficits after brain injury warrant further investigation...

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báo cáo hóa học:" Implantation of neural stem cells embedded in hyaluronic acid and collagen composite conduit promotes regeneration in a rabbit facial nerve injury model" doc

Danh mục: Hóa học - Dầu khí

... results in the regeneration process of peripheral nerve injury [9,22] Severe scarring and fibrosis are the most frequent problems Hyaluronic acid (HA) and collagen are ubiquitous and are major ... amplitude of electromyogram and number, thickness, circumference and area of myelinated nerve fibers derived from rabbits with and without facial nerve injury and repair using NSC-embedded NT-3-supplemented ... used to observe, record, and analyze animal behaviour in terms of signs and extents of muscular atrophy of lips, blink reflex, and ear motion of animals before and 12 weeks after peripheral nerve...

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Báo cáo sinh học: "Safety and feasibility of third-party multipotent adult progenitor cells for immunomodulation therapy after liver transplantation–a phase I study (MISOT-I)" doc

Danh mục: Điện - Điện tử

... bed after injection and cause micro- or macroembolism To monitor for potential embolus formation, we have specified diagnostic procedures to examine the liver and lung after intraportal and intravenous ... applied on days and after transplantation; g mycophenolic acid (MPA) will be applied per day given as a split dose Steroids will be started on postoperative day and tapered by month after liver transplantation, ... contributing to vascular regeneration in models of limb ischemia [23], improving cardiac function after myocardial infarction [24], and contributing to the regeneration of injured livers through their...

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báo cáo hóa học:" Safety and feasibility of third-party multipotent adult progenitor cells for immunomodulation therapy after liver transplantation–a phase I study (MISOT-I)" pptx

Danh mục: Hóa học - Dầu khí

... bed after injection and cause micro- or macroembolism To monitor for potential embolus formation, we have specified diagnostic procedures to examine the liver and lung after intraportal and intravenous ... applied on days and after transplantation; g mycophenolic acid (MPA) will be applied per day given as a split dose Steroids will be started on postoperative day and tapered by month after liver transplantation, ... contributing to vascular regeneration in models of limb ischemia [23], improving cardiac function after myocardial infarction [24], and contributing to the regeneration of injured livers through their...

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Báo cáo sinh học: "Transplanted astrocytes derived from BMP- or CNTF-treated glialrestricted precursors have opposite effects on recovery and allodynia after spinal cord injury" docx

Danh mục: Báo cáo khoa học

... days after injury in untreated control animals [18] However, by days after injury and GDACNTF transplantation, neurocan and NG2 immunoreactivity at sites of injury was similar in intensity and ... days after injury and transplantation BDA-labeled axons were counted in every third sagittally oriented section within the injury center and at points 0.5 mm, 1.5 mm and mm rostral to the injury ... each into medial and lateral regions of the rostral and caudal injury margins, and two injections into medial and lateral regions of the injury center (Figure 1b) All dorsal column injury experiments...

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Báo cáo y học: "Characteristics of repair tissue in second-look and third-look biopsies from patients treated with engineered cartilage: relationship to symptomatology and time after implantation" ppsx

Danh mục: Báo cáo khoa học

... months after implantation and in 27.3% of those taken after that period Mixed tissue was present in 20.3% of biopsies taken within 18 months after implantation and in 27.3% of those taken after ... cartilage repair and regeneration Clin Orthop Relat Res 1997, 342:254-269 Hunziker EB: Articular cartilage repair: basic science and clinical progress A review of the current status and prospects ... data collection and analysis, and the write up SCD carried out the data collection and analysis BZ carried out the data collection and analysis RC carried out the patient recruitment and application...

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Báo cáo y học: " International symposium on peripheral nerve repair and regeneration and 2nd club Brunelli meeting" pdf

Danh mục: Báo cáo khoa học

... article as: Turgut and Geuna, International symposium on peripheral nerve repair and regeneration and 2nd club Brunelli meeting Journal of Brachial Plexus and Peripheral Nerve Injury 2010, 5:5 ... distributed under the 2010, References The International Symposium Peripheral Nerve Repair and Regeneration and 2nd Club Burnelli Meeting [http:// ... manuscript and have read/approved the final manuscript Author Details 1Department of Neurosurgery, Adnan Menderes University School of Medicine, AydRn, Turkey and 2Department of Clinical and Biological...

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Repair and Regeneration of Ligaments, Tendons, and Joint - part 2 ppt

Danh mục: Sức khỏe giới tính

... middle and ring fingers and the ring and little fingers Type 3: slips between the middle and ring fingers and the ring and little finger, including EDM Two subtypes were defined: Type 3y: splits and ... compartment A strong central fibrous band also reaches to the third metacarpal, causFrom: Orthopedic Biology and Medicine: Repair and Regeneration of Ligaments, Tendons, and Joint Capsule Edited by: W ... band and lateral digital sheet (7,8) Grayson’s and Cleland’s ligaments are also in the digit and are essential for normal cutaneous stability during digital movements (9) Flexor Musculature and...

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Repair and Regeneration of Ligaments, Tendons, and Joint - part 3 docx

Danh mục: Sức khỏe giới tính

... four-strand modified Kessler technique (65), it does provide the strength of a four-strand repair with the simplicity and tendon handling requirements of only a two-stranded repair Suture material and ... twice as strong as a two-stranded repair and, consequently, a six-stranded repair being almost three times stronger Several authors have even described eightstranded repair techniques (73,74) Unfortunately, ... skilled hand therapist, and a compliant and motivated patient The future of tendon repair lies in the ability to produce a repair that is immediately robust enough to withstand the demands of...

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Repair and Regeneration of Ligaments, Tendons, and Joint - part 8 pptx

Danh mục: Sức khỏe giới tính

... From: Orthopedic Biology and Medicine: Repair and Regeneration of Ligaments, Tendons, and Joint Capsule Edited by: W R Walsh © Humana Press Inc., Totowa, NJ 257 258 Hill, An, and Young normal ligament ... midsubstance Regardless of the mechanism, the From: Orthopedic Biology and Medicine: Repair and Regeneration of Ligaments, Tendons, and Joint Capsule Edited by: W R Walsh © Humana Press Inc., Totowa, ... relate to pain and/ or functional deficit, in addition to the problems arising from the initial injury Furthermore, the harvest and preparation of any graft prolongs the operation After the operation,...

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Repair and Regeneration of Ligaments, Tendons, and Joint - part 9 ppt

Danh mục: Sức khỏe giới tính

... in ACL regeneration: (1) the complex structure and function of the ACL; (2) inadequate healing in the ACL and the “race” between repair and regeneration; and (3) limitations of the grafts and biomaterials ... possibility of 282 Dunn regeneration; i.e., there is a “race” between repair and regeneration, and repair wins This makes sense from an evolutionary standpoint: rapid repair renders functionality ... tunnels each in the femur and tibia and two ligament strands to simulate the anteromedial and posterolateral bands Long-chain polyethylene fibers were used for the ligaments, and staples were used...

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Repair and Regeneration of Ligaments, Tendons, and Joint - part 10 doc

Danh mục: Sức khỏe giới tính

... 70, 71 repair, extensor tendons, zone I injury, 62, 63 zone II injury, 63 zone III injury, 63, 64 zone IV injury, 64 zone V injury, 64 zone VI injury, 64 zone VII injury, 64, 65 zone VIII injury, ... HVJ, and the method has been successfully used for the introduction of foreign genes and antisense oligonucleotides (ODN) into several organs and tissues Gene Therapy in Ligament and Tendon Repair ... quality of scar material can lead to seriFrom: Orthopedic Biology and Medicine: Repair and Regeneration of Ligaments, Tendons, and Joint Capsule Edited by: W R Walsh © Humana Press Inc., Totowa,...

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Báo cáo y học: " Attenuation of lung inflammation and fibrosis in CD69-deficient mice after intratracheal bleomycin" potx

Danh mục: Báo cáo khoa học

... unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited Attenuation of lung inflammation and fibrosis in CD69-deficient mice after intratracheal bleomycin ... head and neck cancers, and germ-cell tumors [5] However, the therapeutic efficacy of BLM is limited by the development of pulmonary fibrosis in patients using it [6, 7] BLM-induced pulmonary fibrosis ... culture tray and incubated with blocking buffer at room temperature for 30 One milliliter of BALF sample was added to each membrane and incubated for h After the samples were removed and washed,...

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Báo cáo y học: "Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254)" ppt

Danh mục: Báo cáo khoa học

... were enrolled as soon after initial injury as possible with a mean baseline enrollment time of 15.2 ± 7.2 days after injury and a mean follow-up time of 47.6 ± 12.4 days after injury with samples ... biomarkers in synovial fluid and 13 in serum soon after acute knee injury and after a period of recovery but prior to surgery Initially we compared the baseline and follow-up data for each biomarker ... arthroscopic or MRI assessments of joint inflammation and injury Discussion It is important to understand the amount and type of joint damage after acute injury to identify novel Catterall et al Arthritis...

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Báo cáo khoa học: "Plasma neutrophil gelatinase-associated lipocalin predicts acute kidney injury, morbidity and mortality after pediatric cardiac surgery: a prospective uncontrolled cohort study" pps

Danh mục: Báo cáo khoa học

... kidney soon after ischemic injury [18-20] NGAL protein was also markedly induced in kidney tubule cells, and easily detected in the plasma and urine in animal models of ischemic and nephrotoxic ... during the first 24 hours after surgery and 100% maintenance subsequently We obtained spot plasma samples at baseline and at frequent intervals (2, 6, 12, and 24 hours) after initiation of CPB ... by the hospital clinical laboratory at baseline and routinely monitored at least twice daily during the first days after CPB, and at least daily after the third postoperative day The primary outcome...

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