references 1 covacci a telford jl del giudice g et al helicobacter pylori virulence and genetic geography science 1999 284 5418 1328 33 2 han j yu e lee i et al diversity among clinical isolates of helicobacter pylori in korea mol cells

Engineering of an efficient and enantioselevtive biocatalyst for the preparation of chiral pharmaceutical intermediates

Engineering of an efficient and enantioselevtive biocatalyst for the preparation of chiral pharmaceutical intermediates

Ngày tải lên : 12/09/2015, 10:22
... TTTGTGACCG GTGGCGCGAG CGGCATTGGT 61 GAAGCCGTGG TGAAACAGCT GGCGGCGCGT GGTGCGAAAG TTGTGGTTGC GGATCTGAAA 12 1 CTGGAAGGTG CGCAGGCCGT GGCGGATGCG GTGAAAGCGG CGGGTGGTGA AGCCGCGGCC 18 1 GTGGCGGTGG ATGTGGCCAA ... ATGTGGCCAA AGCGGATCAG GTGGAAAAAG CGGTTCAGTT TGCGGTGGAT 2 41 ACCTTTGGTG CGCTGCATCT GGCGGTGAAC AATGCGGGCA TTGGTGGCGC GAGCGCGCCG 3 01 CTGGGTGATT ATAGCTTTGA TGATTGGCAT CGTGTGATCG ATGTGAACCT GAACAGCGTG 3 61 ... TTTTATAGCA TGAAATATGA AATTGTTGCC ATGCTGCGCG CGGGTGGCGG CGCCATTGTG 4 21 AACATGGCGA GCATTCTGGG TAGCGTGACC TTTCCGAATG CGCCGGCCTA TGTTACCGCG 4 81 AAACACGGCG TGGTGGGCAT GACCAAAAGC GCCGCCGTTG ATTATGCCAA...
  • 174
  • 539
  • 0
Tài liệu Báo cáo khoa học: Medium-chain dehydrogenases/reductases (MDR) Family characterizations including genome comparisons and active site modelling pdf

Tài liệu Báo cáo khoa học: Medium-chain dehydrogenases/reductases (MDR) Family characterizations including genome comparisons and active site modelling pdf

Ngày tải lên : 21/02/2014, 03:20
... replacement procedure is a conjugate gradient minimization of 10 00 functional evaluations to relieve any remaining unfavourable side chain interactions The volume of the active site is measured ... branches early, which indicates a divergent superfamily of ancient origin where a limited number of ancestral genes have diverged during the evolution of the separate species The eight families ... elegans: a platform for investigating biology Science 28 2, 2 0 12 2 018 The Arabidopsis Genome Initiative (20 00) Analysis of the genome sequence of the flowering plant Arabidopsis thaliana Nature 408,...
  • 10
  • 316
  • 0
Báo cáo khoa học: The lactate dehydrogenases encoded by the ldh and ldhB genes in Lactococcus lactis exhibit distinct regulation and catalytic properties ) comparative modeling to probe the molecular basis pdf

Báo cáo khoa học: The lactate dehydrogenases encoded by the ldh and ldhB genes in Lactococcus lactis exhibit distinct regulation and catalytic properties ) comparative modeling to probe the molecular basis pdf

Ngày tải lên : 16/03/2014, 05:20
... residues (Ala253 and Val254 in LDH are replaced by Val253 and Ile254 in LDHB) The histidine and arginine residues directly involved in catalysis are identical in the two enzymes, and NADH binding ... homofunctional enzymes displaying clear differences in kinetic and regulatory parameters Therefore, we deemed it interesting to compare glycolysis in the two strains and examine FEBS Journal 27 4 ... general, the resulting mutant strains metabolize glucose via a mixed acid fermentation, producing ethanol, acetate, formate, acetoin, and 2, 3-butanediol Additionally, production of lactic acid...
  • 13
  • 464
  • 0
Báo cáo khoa học: High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract Implications for Parkinson’s disease docx

Báo cáo khoa học: High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract Implications for Parkinson’s disease docx

Ngày tải lên : 16/03/2014, 11:20
... GGTTAACGGAGAGGCTTTGGGCACTGGGAGGCACCCCGACAATGACGCT TGGCCTAGAACTGCAGGAAGAGGCGTGAACAGGGATCCACTAACCGCGT CTCTCCACACTCTTCCATCCTCCAAAGGCGGTGCCTTTCCATGTGCGTC GACACTCTCCACACTCTTCCAGCCTCCAAAGGCAGTGCCTTTCCACGTG ... TCATCTCTGCTCTTCCACCCTCCAAAGACGCAGCCCTTCCACGTACGCC CCCAGCACAGAACACCCAGCTCTCTGGATCTCAAAATGTCAGGACAGTCCG CATCATCTCTGCTCTTCCAACCACCAAAGACGCAGCCCTTCCATGTCCG GTGATATCAGAGAACACTGTCAGGAACAAGGCTTCAGGTCACGGTCGC ... that a putative environmental pathogenic agent, capable of passing the GI epithelial lining, might induce a- synuclein misfolding and aggregation in specific neurons of the intestinal neuronal plexuses...
  • 12
  • 504
  • 0
Báo cáo khoa học: Prediction of coenzyme specificity in dehydrogenases ⁄ reductases A hidden Markov model-based method and its application on complete genomes doc

Báo cáo khoa học: Prediction of coenzyme specificity in dehydrogenases ⁄ reductases A hidden Markov model-based method and its application on complete genomes doc

Ngày tải lên : 23/03/2014, 10:21
... training the two HMMs, one with FAD-binding sequences and one with NAD(P)-binding sequences, using sequences from five of the groups and testing against the remaining group and a false data set The ... of interest and the others deviate in their coenzyme-binding manner The resulting data set, with 12 0 members, was manually aligned based upon their three-dimensional structures, and divided into ... Short-chain dehydrogenases ⁄ reductases FAD-dependent pyridine nucleotidedisulphide oxidoreductases Flavin-containing amine oxidases FAD-dependent oxidoreductases Zinc-containing alcohol dehydrogenases...
  • 8
  • 481
  • 0
Báo cáo khóa học: Acyl-CoA dehydrogenases and acyl-CoA oxidases Structural basis for mechanistic similarities and differences pot

Báo cáo khóa học: Acyl-CoA dehydrogenases and acyl-CoA oxidases Structural basis for mechanistic similarities and differences pot

Ngày tải lên : 23/03/2014, 12:20
... docking site in MCAD and the corresponding site in ACO (A) A view of MCAD indicating the hypothetical ETF docking site as modeled by Roberts et al [33] a- Helical domain (red), b-sheet domain (cyan), ... lies at the surface of the molecule (Fig 2B) The tetrameric molecule is a dimer of dimers in a tetrahedral arrangement ˚ with an overall diameter of about 90 A (Fig 2B) The interactions between ... N-terminal a- helical domain, the middle b-sheet domain, and the C-terminal a- domain are colored in red, cyan, and green, respectively (B) A ribbon diagram of a tetramer of MCAD The molecule is viewed along...
  • 11
  • 296
  • 0
Báo cáo khóa học: Genetic defects in fatty acid b-oxidation and acyl-CoA dehydrogenases Molecular pathogenesis and genotype–phenotype relationships ppt

Báo cáo khóa học: Genetic defects in fatty acid b-oxidation and acyl-CoA dehydrogenases Molecular pathogenesis and genotype–phenotype relationships ppt

Ngày tải lên : 23/03/2014, 12:20
... there is a clear correlation between the degree of deficiency and the clinical phenotype ( [1] and references therein) Severe deficiencies generally result in fatal or severe disabilities, while ... conditions under which the deficiency occurs and to delineate whether there exist inter-individual genetic differences in susceptibility to develop clinical disease Generalization and future aspects ... deficiency, and include hyperinsulinism Only time will show the degree of clinical and genetic heterogeneity in this rare disease Molecular effect of sequence variations with an a priori unpredictable...
  • 13
  • 407
  • 0
Báo cáo khoa học: Inhibition kinetics of catabolic dehydrogenases by elevated moieties of ATP and ADP – implication for a new regulation mechanism in Lactococcus lactis potx

Báo cáo khoa học: Inhibition kinetics of catabolic dehydrogenases by elevated moieties of ATP and ADP – implication for a new regulation mechanism in Lactococcus lactis potx

Ngày tải lên : 29/03/2014, 08:20
... in eukaryotic ADHs, indicating that this type of inhibition might be widespread in nature Results Inhibition kinetics by a single inhibitor The inhibition kinetics of lactococcal GAPDH, LDH and ... moiety and the in vitro-determined inhibition of GAPDH, LDH and ADH by ATP and ADP independently Herein we characterize the inhibition kinetics of these three dehydrogenases with their most important ... of cell extract were used for each assay to test the linearity of the initial enzyme activities with the protein concentration All assays were based on determining the initial conversion rates...
  • 10
  • 503
  • 0
Báo cáo hóa học: " Genetic variation and recombination of RdRp and HSP 70h genes of Citrus tristeza virus isolates from orange trees showing symptoms of citrus sudden death disease" potx

Báo cáo hóa học: " Genetic variation and recombination of RdRp and HSP 70h genes of Citrus tristeza virus isolates from orange trees showing symptoms of citrus sudden death disease" potx

Ngày tải lên : 20/06/2014, 01:20
... Rangpur lime nor sweet orange appear sensitive to the disease in isolation and diseased trees can sometimes be salvaged by removing the sweet orange graft There is some circumstantial evidence ... 0.05 Figure Phylogenetic and recombination analysis of 28 6 RdRp gene fragments sampled from three Brazilian orange trees Phylogenetic and recombination analysis of 28 6 RdRp gene fragments sampled ... Figure Phylogenetic and recombination analysis of 28 4 HSP70h gene fragments sampled from three Brazilian orange trees Phylogenetic and recombination analysis of 28 4 HSP70h gene fragments sampled...
  • 7
  • 346
  • 0
Báo cáo lâm nghiệp: "Changing electrophoretic patterns of glutamate dehydrogenases and aspartate aminotransferases in a few tree species under the influence of ectomycorrhization" potx

Báo cáo lâm nghiệp: "Changing electrophoretic patterns of glutamate dehydrogenases and aspartate aminotransferases in a few tree species under the influence of ectomycorrhization" potx

Ngày tải lên : 09/08/2014, 04:20
... 12 3, 12 35 - 12 42 Lea P .J & Miflin B.B (19 74) An alternative route for nitrogen assimilation in higher plants Nature 2 51, 614 - 616 References Blumenthal K.H & Smith E. L (19 73) Nicotinamide adenine dinucleotide ... the peri- pheral mycelial layer (Table II) Conclusion In all the associations investigated, fungal AAT was strongly repressed, whereas fungal NADP-GDH was only repressed in beech!ctomycorrhizas ... spruce confirmed these results: the vascular cylinder free of fungus and the cortical region including host cells and fungal hyphae revealed identical isoforms, while no activity was found in the...
  • 3
  • 240
  • 0
KINETIC ANALYSIS OF PRIMATE AND ANCESTRAL ALCOHOL DEHYDROGENASES

KINETIC ANALYSIS OF PRIMATE AND ANCESTRAL ALCOHOL DEHYDROGENASES

Ngày tải lên : 24/08/2014, 12:25
... Figure 5: Phylogenetic Relationship of ADH1 Paralogs1 Figure Phylogenetic relationship of ADH1 paralogs as determined by Bayesian analysis of exonic sequence data using a codon model, including ... alcohol is an environmental teratogen, it is unclear which principal agent (ethanol itself or acetaldehyde) triggers the developmental abnormalities in the brain during gestation (Hurley et al 20 02) ... substrates increase in chain length [Table 3] These kinetic properties arise from the presence of methionine at position 14 1—which relieves steric hindrance in the substrate binding site—yielding...
  • 83
  • 93
  • 0
TRANSCRIPTIONAL REGULATION OF THE HUMAN ALCOHOL DEHYDROGENASES AND ALCOHOLISM

TRANSCRIPTIONAL REGULATION OF THE HUMAN ALCOHOL DEHYDROGENASES AND ALCOHOLISM

Ngày tải lên : 24/08/2014, 12:37
... fetal liver6 as mRNA in fetal and adult liver6 Common substrates ethanol 12, retinol13 ethanol 12, retinol13 ethanol 12, retinol13 ethanol 12, retinol13 HMGSH14 ,15 , GSNO16 retinol13, ethanol 12 ethanol 12 ... statistical analysis of differential gene expression and alternative splicing and finally biological significance of the affected genes in the experiment Quantile normalization of the data is carried out ... gene by alternative splicing Alternative splicing generates another layer of gene regulation and recent estimates suggest that 929 4% of the human genes are alternatively spliced (Wang et al. , 20 08)...
  • 215
  • 370
  • 0
EMBEDDED LINUX SYSTEM DESIGN AND DEVELOPMENT.pdf

EMBEDDED LINUX SYSTEM DESIGN AND DEVELOPMENT.pdf

Ngày tải lên : 04/08/2012, 14:23
... the scope of embedded Linux and related applications is so large that getting a feel for what is available and what can be done is challenging Seeing all the pieces separately and working together ... adheres to LSB In this year Linux saw more inroads in the digital entertainment industry Intel announced a reference design for a home digital media adapter Trace Strategies Inc published a research ... file compare and merge, and so on – Debugger: Multithreading/multiprocess debugging, source- and assembly-level debugging; hardware debugging support using JTAG interface – Toolchain: Integrated...
  • 429
  • 1.7K
  • 2
09 Physical and Chemical Characteristics of DDGS revisions.

09 Physical and Chemical Characteristics of DDGS revisions.

Ngày tải lên : 08/08/2012, 10:03
... reduce mixing time in order to achieve a uniformly distributed mix of ingredients in a complete feed Amount of ingredient segregation during transport and handling – particle and ingredient segregation ... 10 12 13 14 15 16 Average Particle Size Mean 13 98 13 22 14 25 13 70 12 55 6 12 974 12 58 11 42 13 37 14 88 12 35 11 98 12 29 21 2 5 11 48 12 82. 25 Standard Deviation 2. 32 2.00 1. 62 1. 84 1. 68 2. 75 2 .15 1. 70 1. 84 ... fines) Bulk density – is a measure describing the weight of an ingredient per unit volume In general, bulk density can be increased by reducing particle size to increase the weight of a feed ingredient...
  • 8
  • 748
  • 0
CHECK YOUR ENGLISH VOCABULARY FOR BUSINESS AND ADMINISTRATION.pdf

CHECK YOUR ENGLISH VOCABULARY FOR BUSINESS AND ADMINISTRATION.pdf

Ngày tải lên : 08/08/2012, 17:31
... 978-0- 713 -67 918 -2) Exercise 2: Instructions as above Accountant Advertising Manager Arbitrator Area / Regional Manager External Auditor Foreman Graduate Trainee IT Consultant Marketing Manager Official Mediator ... continuous personal development (CPD) experiential learning an induction course in- tray learning modern apprenticeship off-the-job training online learning open learning total quality management ... covering letter CV drive (noun) experience incentive increment interview leading (adjective) motivate post qualified relocation allowance responsibilities rewards package team vacancy Sandra:...
  • 82
  • 6K
  • 56
Check Your English Vocabulary for Phrasal Verbs and Idioms.pdf

Check Your English Vocabulary for Phrasal Verbs and Idioms.pdf

Ngày tải lên : 08/08/2012, 17:32
... italics in these sentences In one case, all options are possible The meaning of each phrasal verb, idiom, etc, in its given context is in italics at the end of each sentence I' ve finally managed ... rolling in it Tarquin is loaded 18 Bob is skint Laurence is hard up 19 Andy is down and out Christine is well off 20 Jeanette is feeling flush 10 Brenda is in the red 21 Charles is raking it in 11 ... To save time, we decided to go over the field instead of walking around it 11 To save time, we decided to go through the shopping centre instead of walking around it 12 The air conditioning will...
  • 81
  • 7.4K
  • 101
Atmel AVR Microcontroller Primer Programming and Interfaceing

Atmel AVR Microcontroller Primer Programming and Interfaceing

Ngày tải lên : 16/08/2012, 09:03
... used at the beginning and end of a data byte These framing bits alert the receiver that an incoming data byte has arrived and also signals the completion of the data byte reception The data rate ... operating parameter options available to select the best option for a given application 1. 5 .1 Packaging The ATmega16 comes in three different packaging styles: a 40-pin plastic dual in- line package ... ATmega16 memory components and their applications, explain the ATmega16 internal subsystems and their applications, highlight the operating parameters of the ATmega16, and summarize the special ATmega16...
  • 194
  • 1.1K
  • 4
Pro WPF and Silverlight MVVM effective Application Development

Pro WPF and Silverlight MVVM effective Application Development

Ngày tải lên : 17/08/2012, 08:54
... CHAPTER ■■■ DataBinding The view provides two services to the user: presenting data and interacting with data The former involves reading data and displaying it in a certain format, whereas the ... properties exhibit this same level of XAML integration 24 CHAPTER ■ DATABINDING Databinding Dependency properties can be set indirectly via databinding This can use the binding object notation but, ... blocking the rest of the view from binding While the binding is retrieving the value, the FallbackValue is displayed, so use this to present users with a suitable message asking for their patience...
  • 273
  • 892
  • 6