... issue of developing thesteelindustryin a scientific and sound manner 1.3 The Rise ofthe Chinese SteelIndustry A review ofthe development ofthe Chinese steelindustry shows that theindustry ... technique, Chinese steelindustry has stepped into stage of healthy development Inthe nineties ofthe twentieth century, Chinese steelindustry boomed In 1996, the output of crude steelin China was ... level of engineering science Inthe new century, the world's steelindustry and in particular thesteel indusaies in China, India, Brazil and other developing countries are in a period of developmental...
... constructed from the training data during the learning phase Each pattern is a set of syntactic dependencies ofthe corresponding reduced graph of a (positive or negative) entity pair inthe training data ... POS-tagging and parsing ofthe sentences Before parsing the sentences, all the entities are blinded by assigning names as EntityX where X is the entity index In each example, the POS tags ofthe ... (see the results in Table 4) As an extension of their work, they boosted system performance by training on multiple PPI corpora instead of on a single corpus and adopting a corpus weighting concept...
... possible that the use of different foot posture measures may account for some ofthe discord between the present study’s findings and those of other investigators Conclusion The findings of this study ... important for the external validity of these findings The mean FPI-6 scores for the non-flat foot group ofthe study (n = 109) indicate that the average foot posture is mildly pronated in children ... kg/m2 in boys and 15.5 - 17.0 kg/m2 in girls The mean BMI for the 140 children in this study was 18.3 ± 3.4 kg/m2, with a wide range of BMI results: 13.7 - 37.9 kg/ m2 The BMI cut-off points of the...
... octahedrally co-ordinated inthe vicinity ofthe active site (Fig 2) Three ofthe six cation ligands are main-chain oxygen atoms, and three are the side-chain oxygen atoms of N296, E342 and S387 The glutamic ... docking site followed by a conformational change in ACP proposed to inject the acyl chain into the substrate-binding pocket [32] If a similar mechanism is involved inthe KAS I reaction then an intermediate ... on the structure ofthe CHN enzyme E coli KAS III and the interpretation ofthe structure ofthe E coli KAS I– ˚ thiolactomycin complex [12], assuming a A movement of H298 on malonyl-ACP binding...
... gene into juxtaposition with the locus ofthe immunoglobulin heavy chain, resulting in overexpression of BCL-2 [61] This in turn inhibits the apoptotic process ofthe lymphoma The relevance of ... binding proteins, including the stabilizing protein HuR [86] and the mRNA destabilizing protein tristetraprolin (TTP) [87] HuR is a member ofthe Hu family of mRNA binding proteins and has been ... is in uenced by elements located within both the coding region and the 3¢-UTR It remains to be determined whether these instability elements inthe coding region and the 3¢-UTR act in a coordinated...
... holds the CK of k, and … the preceding word of k is tagged z the following word of k is tagged z the second preceding word of k is tagged z the second following word of k is tagged z the preceding ... sentence from a linguistic point of view However, we conclude that this kind of sentence is as important as the other explicit comparisons from an engineering point of view After defining the seven ... word of k is tagged z, and the following word of k is tagged w the preceding word of k is tagged z, and the second preceding word of k is tagged w the following word of k is tagged z, and the...
... of their crystal structure of Pisum sativum PSI, in which the loop of PSI-G is suggested to face the stroma The amount of PSI-G inthe transformed knock-out line does not reach the level ofthe ... conformation ofthe loop His-tags were employed in a topological study ofthe major light harvesting chlorophyll a ⁄ b binding apoprotein, Lhcb1 [18] Interestingly, fusion of a His-tag to the C-terminus, ... light harvesting complex (LHCI), consisting of four members (Lhca1–4) ofthe chlorophyll a ⁄ b binding protein family LHCI is bound along one side of PSI only, inthe vicinity ofthe PSI-F and...
... located inthe A and B domains, respectively Further mutations have led to the general consensus that the B and C domains contain residues most involved in IGF1R binding, the A domain represents the ... bind to the IGF1R Previously we have expressed a recombinant form ofthe human IGF1R by fusing the cDNA encoding the receptor ectodomain (residues 1±944) to the cDNA ofthe mouse Fc domain of ... IGF2R-binding site, while the B domain and the ®rst A domain helix contain the major determinants for IGFBP binding In this study we show, using IGF-I, IGF-II and 14 IGF analogues, that potency in...
... main results of this section Proof of Theorem 2.6 The proof of Theorem 2.6 is completely analogous to that of Theorem 2.3 inthe quasilinear case using W 2k , k+1 in place of W1, p k+1 and Theorem ... Characterizations ofthe existence of u ≥ 0, −u ∈ Φk (Ω), continuous near ∂Ω, which solves (7.1), can be obtained using the iteration scheme employed inthe proof of Theorem 6.11 along with weak continuity of ... used inthe studies ofthe p-Laplacian [HKM], [KM2] plays a secondary role inthe theory of equations of Lane-Emden type Relations between these and other capacities used in nonlinear PDE theory...
... equally effective inhibitors of protein synthesis in cell extracts, the absence ofthe B-chain in type does not allow the protein to bind and enter cells with high efficiency Therefore they are considerably ... helices A–J The N-termini and C-termini ofthe protein are marked The molecule comprises two structural domains: domain I at the N-terminal part and domain II at the C-terminal end Discussion In this ... in parentheses Fig S2 Possible DNA sequences of charybdin and homologous proteins coding for the N-terminal and C-terminal region of charybdin after alignment ofthe protein sequences Underlined...
... domain of EstD has similarity to the MecA N-terminus but could not be modeled The function ofthe N-terminus remains unclear It might be involved in selection ofthe substrates, either by binding of ... domains present inthe encoded protein were analyzed using the NCBI Conserved Domain Search EstD belongs to the COG1073, comprising hydrolases ofthe a ⁄ b superfamily Furthermore, the C-terminal ... sides of Ser243 The alcohol side ofthe substrate is in a groove pointed towards the entrance ˚ ofthe pocket and extends approximately 10 A from Ser243 The acyl-side ofthe ligand fits in a less...
... maximum number of features appropriate to any type is , and there are types inthe signature, then the cost of this is dominated by the cost of expanding the products, , since inthe worst case ... linear time in both the number of features and types Subtype covering results in NP-complete non-disjunctive type inferencing, but the postponement of these constraints using constraint handling ... order to contain this That yields something roughly ofthe form shown in Figure 3, which is an example of a recent trend in using type-intensive encodings of linguistic information into typed feature...
... cross-link the smelt AFP dimers using the homobifunctional cross-linking agent BS3, dimerization must result inthe placement of two primary amines, from either lysine side chains, or the ˚ N-terminus, ... bands of 18 kDa and dimer bands of 33 kDa To examine whether Ca2+ binding was required for dimerization, smelt AFP was incubated with BS3 in buffer containing 10 mM EDTA instead of CaCl2 Inthe ... to generate the accumulation of a larger protein form With increasing concentrations of BS3, the disappearance ofthe monomer band corresponded to the gradual increase in intensity of a higher-molecular-mass...
... spectra ofthe second Kunitz–type protease inhibitor module of human WFIKKN The solid line indicates the spectrum ofthe recombinant protein, the dotted line indicates the CDPro-predicted spectrum of ... trypsin–inhibitor complex, Ki was determined from the replot ofthe apparent Km values vs the inhibitor concentration at which they were obtained Inthe case of chymotrypsin, plasmin, thrombin, ... characterization ofthe second Kunitz-domain ofthe WFIKKN protein In view ofthe fact that an arginine residue is present inthe P1 position of WFIKKN-KU2 (Fig 3), it was not unexpected that the recombinant...
... observed inthe mutant, apart from the changed atoms ofthe mutated side chains In order to evaluate further the design ofthe mutations, it was of interest how the stability behaviour ofthe protein ... clearly from the derivative plot in Fig 1B, from which the melting temperatures (Tm) were also calculated When the unfolding ofthe intact enzyme (containing the CBD) was compared to that ofthe catalytic ... ofthe release ofthe substrate Comparison ofthe Cel7A unfolding with and without the substrate either at pH 8.0 (Fig 3A and B), or pH (Fig 3C and D) shows interestingly that the unfolding of...
... shown at the right of each exon interesting note is the increasing size of each ofthe three introns, i.e intron < intron < intron (Fig 2A), is maintained between fishes and mammals All intron/exon ... solid lines The length ofthe boxes and lines represent the approximate size ofthe exons and introns, respectively, with the number of amino acids encoded by each exon shown above the boxes The ... represents the 5¢ end ofthe mature B-FABP mRNA The 5¢ RACE product contained a 166 bp sequence corresponding to a portion of exon including the 5¢ UTR ofthe Fig Product of 5¢ RLM-RACE derived from the...
... LSMO/LMO superlattice an increase inthe compressive strain of LMO inthe superlattice structure enhanced the TP inthe superlattices This conclusion is supported by an increase inthe superlattice LMO ... scans of LSMO/LMO on STO show all four films peaks separated by 90 , confirming in- plane epitaxy for all layers ofthe superlattice In order to determine the degree of relaxation and strain inthe ... interfaces If the thermal conductivity can be suppressed while enhancing the power factor (increased square ofthe Seebeck coefficient due to energy filtering that more than offsets the decrease in cross-plane...
... reduction in replication in either the mean peak virus titer or the mean sum ofthe daily virus titers (a measure ofthe total amount of virus shed over the duration ofthe infection) in either the ... mutations in a vaccine candidate Indeed, since this deletion occurs in an ORF (in which the triplet nature ofthe codons must be maintained) and in a virus that conforms to the rule of six (in which the ... substitutions of R84 to G in C, and E87 to G in P (Table 1) [15] The CR84G mutation is attenuating inthe upper respiratory tract (URT) of AGMs, but only inthe presence ofthe HNT553A point mutation indicated...
... reduction in replication in either the mean peak virus titer or the mean sum ofthe daily virus titers (a measure ofthe total amount of virus shed over the duration ofthe infection) in either the ... mutations in a vaccine candidate Indeed, since this deletion occurs in an ORF (in which the triplet nature ofthe codons must be maintained) and in a virus that conforms to the rule of six (in which the ... substitutions of R84 to G in C, and E87 to G in P (Table 1) [15] The CR84G mutation is attenuating inthe upper respiratory tract (URT) of AGMs, but only inthe presence ofthe HNT553A point mutation indicated...
... year, cut-off defined according to the recommendations ofthe national agency of accreditation and evaluation in health care in 2001) These were measured using the adapted version ofthe Diabetes ... from the health insurance system database) were first tested by using analysis of variance (in the case of categorical independent variables) or simple linear regression (in the case of continuous ... functioning In 2007, ENTRED will be repeated in order to measure the possible evolution since 2001 Moreover, the use ofthe SF12, a generic instrument will permit a comparison of HRQoL within the...