rare tumors of the skin and subcutaneous tissue
báo cáo khoa học: "Triple malignancy in a single patient including a cervical carcinoma, a basal cell carcinoma of the skin and a neuroendocrine carcinoma from an unknown primary site: A case report and review of the literature" ppt
Ngày tải lên :
10/08/2014, 23:20
... In the case that we present, the histological type of the skin lesion as a basal cell carcinoma and the long survival after the local control of both tumors might exclude the hypothesis of skin ... addition, a skin inspection found a cm solitary nodule on the dorsum of the nose: the lesion bled spontaneously at the examination and biopsy confirmed the diagnosis of basal cell carcinoma of the skin ... involved in the analysis of the data and the literature research, and he also wrote the manuscript SB helped with the patient management and revision of the manuscript TM helped with the literature...
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Practice Guidelines for the Diagnosisand Management of Skin and Soft TissueInfections: 2014 Update by the InfectiousDiseases Society of America
Ngày tải lên :
14/04/2016, 19:08
... wooden-hard induration of the subcutaneous tissues In cellulitis, the subcutaneous tissues are palpable and yielding; in fasciitis the underlying tissues are firm, and the fascial planes and muscle groups ... subsequent episode of fever and neutropenia (recurrent) (strong, low) 60 Aggressively determine the etiology of the SSTI by aspiration and/ or biopsy of skin and soft tissue lesions and submit these for ... diagnosis and an appropriate index of suspicion for specific etiological agents Recognition of the physical examination findings and understanding the anatomical relationships of skin and soft tissue...
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Báo cáo khoa học: Hierarchical subfunctionalization of fabp1a, fabp1b and fabp10 tissue-specific expression may account for retention of these duplicated genes in the zebrafish (Danio rerio) genome docx
Ngày tải lên :
07/03/2014, 12:20
... are the paralogs of the fabp10 gene and the proto-fabp1 gene diverged from the fabp10 gene before the fish-tetrapod split, 679 mya [2] Tissue- specific distribution of the fabp1a, fabp1b and fabp10 ... in the residues involved in the binding at site of the human FABP1, and possibly in zebrafish FABP1a and zebrafish FABP1b, may reflect differences in the binding affinities of the zebrafish FABP1a and ... independent of other fish lineages Analysis of fabp1a and fabp1b genes in various fish species would likely resolve the timing of the insertion of intron in the fabp1a gene Linkage group assignment of zebrafish...
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Báo cáo khoa học: Cloning of a rat gene encoding the histo-blood group A enzyme Tissue expression of the gene and of the A and B antigens potx
Ngày tải lên :
31/03/2014, 09:20
... the parietal cells of the gastric glands whereas the B antigen was present on the pits epithelial cells and the chief cells of the glands In the large intestine and the caecum, the A antigen was ... concordance between the presence of the mRNA and of the A antigen in tissues Nevertheless, there were some discrepancies in tissues such as the kidney and the urinary bladder where the mRNA was easily ... detected in fewer tissues than the A antigen It could not be found in the tongue, the oesophagus, the parotid gland, the uterus, the seminal vesicle, the thyroid and parathyroid glands and the Fig Immunohistochemical...
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báo cáo hóa học: " Safety evaluation of topical applications of ethanol on the skin and inside the oral cavity" pdf
Ngày tải lên :
20/06/2014, 00:20
... matter of debate, and there appears to be scientific evidence pointing in both directions On the one hand, researchers came to the conclusion that the range of damage caused to the skin by the alcohol ... of age) and one adult The legs of the subjects were wrapped in cotton from above the knees to the feet, and the wrappings were subsequently soaked with 200 ml of 95% (v/ v) ethanol Although the ... The authors found that their research may pose public health implications due to the presence of these compounds in consumer products, especially the simultaneous use of ethanol and the gel of...
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Báo cáo khoa học: "Malignant mixed Mullerian tumors of the uterus: histopathological evaluation of cell cycle and apoptotic regulatory proteins" ppt
Ngày tải lên :
09/08/2014, 03:21
... Carcinosarcomas of the female genital tract A pathologic study of 29 metastatic tumors: further evidence for the dominant role for the epithelial component and the conversion theory of histogenesis ... family of genes and the ICE family of proteases These components interact with other cell cycle related genes such as p53 The central role of the Bcl-2 family of genes in the regulation of apoptosis ... numerous malignant tumors [2], there is limited data that explores the role of these oncoproteins with survival data in MMMTs The aim of this study is to evaluate the role of cell cycle and apoptotic...
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Báo cáo khoa học: "Prognostic factors for lymph node metastasis from advanced squamous cell carcinoma of the skin of the trunk and extremities" doc
Ngày tải lên :
09/08/2014, 07:21
... Carcinoma of the skin of the trunk and limbs: The incidence of metastases and their outcome Aust N Z J Surg 1992, 62:697-701 Ames FC, Hickey RC: Squamous cell carcinoma of the skin of the extremities ... months) The distribution of the lymph node metastasis in all cases is presented in Table 21 of those patients underwent lymph node dissection, and of them recurred at the lymph node basin Of 11 ... the area of the tumor This was observed also in other studies [10,18] The association of UV damage and a burn or chronic wound may be associated to the aggressiveness and metastasis in these patients...
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Báo cáo y học: "Demonstration of the histopathological and immunohistochemical effects of a novel hemostatic agent, ankaferd blood stopper, on vascular tissue in a rat aortic bleeding mode" pps
Ngày tải lên :
10/08/2014, 09:22
... specimen was cut into three sections: the proximal, intact part of the aorta, the wounded part of the aorta, and the distal, intact part of the aorta Following the dehydration process using graded ... syringe Either an ABS-soaked or plain gauze tampon was applied to Page of the vascular wound, and the bleeding time was recorded In case of insufficient hemostasis using either of the tampons, ... compliance with the “Principles of Laboratory Animal Care” formulated by the National Society for Medical Reseacrh and “Guide for the Care and the Use of Laboratory Animlas” prepared by the US Natinoal...
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Wound Healing and Ulcers of the Skin - part 1 pps
Ngày tải lên :
10/08/2014, 18:20
... algorithmic approach to the treatment of chronic wounds The caring of wounds has always been the realm of the various branches of surgery Dermatology, on the other hand, being the medical science ... and for actively supporting the production of this book; to Mrs Rina Ben-Zeev for her assistance in the preparation of the Appendix section of the book and for constructive collaboration at the ... in which the epidermis and at least the upper dermis have been destroyed [1] (Figs 1.1, 1.2) An ‘erosion’, on the other hand, is a focal loss of the epidermis without involvement of the dermis...
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Wound Healing and Ulcers of the Skin - part 2 pptx
Ngày tải lên :
10/08/2014, 18:20
... Identification of Bacteria and the Use of Antibiotics A further aspect of the history of wound healing took place in parallel to that of the use of antiseptics, identification of bacteria and the development ... Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig Nature 1962; 193 : 293–294 30 Hinman CD, Maibach H: Effect of air exposure and occlusion ... and other sarcomatous tumors Other soft tissue tumors Histiocytosis syndromes Malignant peripheral nerve tumors Other tumors (non-cutaneous) that may affect skin By direct invasion into the skin...
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Wound Healing and Ulcers of the Skin - part 3 ppsx
Ngày tải lên :
10/08/2014, 18:20
... glucocorticoid therapy may be detrimental to the quality of the skin in these cases, thus further hindering the repair of cutaneous ulcers Vasculitic involvement may induce ulceration in other connective tissue ... morphological characteristics that may direct the physician to the underlying cause are (a) the appearance of the ulcer’s margin and (b) the appearance of the skin around the ulcer Fig 5.3 Bluish discoloration ... Etiology The breaking down of lymph nodes and subsequent ulceration is characteristic of scrofuloderma It occurs in the supraclavicular, parotidal, and submandibular areas and on the lateral aspect of...
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Wound Healing and Ulcers of the Skin - part 4 pot
Ngày tải lên :
10/08/2014, 18:20
... places The extent of undermining can be drawn on the skin around the ulcer These markings are important for assessing the progress of the ulcer and the effectiveness of treatment Additionally, the ... Assessment of the ulcer area Depth The presence and extent of undermining Parameters of wound/ulcer infection Assessment of the appearance of the ulcer surface Then we detail parameters of assessment ... Extravasation of red blood cells – secondary to injury of the blood vessels Other signs of damage to the wall may be present, such as the degeneration of collagen fibers, and the necrosis of endothelial...
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Wound Healing and Ulcers of the Skin - part 5 pot
Ngày tải lên :
10/08/2014, 18:20
... Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig Nature 1962; 193 : 293–294 Hinman D, Maibach H: Effect of air exposure and occlusion ... to the wound surface Removal of the dressing may then strip away newly forming epithelium [3] On the other hand, the probability of epithelial injury with the use of hydrogel or hydrocolloid dressings ... anatomical location ¼ Note the presence of erythema, record the nature and color of granulation tissue as well as the presence and color of secretions ¼ Make a tracing of the ulcer margin (or take...
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Wound Healing and Ulcers of the Skin - part 6 docx
Ngày tải lên :
10/08/2014, 18:20
... involve the determination of appropriate and accurate regimens for the administration of systemic antibiotics, together with the development of ways to improve the penetration and/ or the efficacy of ... parameters such as the etiology of the ulcer, its depth, extent of the infection, and the suspected microorganism present For the time being, a reasonable approach is based on the depth of the ulcer When ... sufficient amount of material such as pus or seropurulent fluid, it can be drawn from the depth of the ulcer with a sterile needle and syringe [24, 25] On the other hand, puncture of tissue with a...
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Wound Healing and Ulcers of the Skin - part 7 ppsx
Ngày tải lên :
10/08/2014, 18:20
... way of decreasing the required area of donor skin is to apply smaller pieces of donor skin, instead of one large sheet that covers the entire area of the ulcer These grafts are placed onto the ... ulcers of various etiologies The mean duration of the ulcers prior to the grafting procedure was 16 years Beneficial effects were manifested either by the appearance of islands of epithelium on the ... ‘take’ of the graft and the final result depend on the ulcer’s condition in terms of vascularization, absence of infection, and appropriate preparation of the ulcer bed, as well as on the patient’s...
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Wound Healing and Ulcers of the Skin - part 8 pdf
Ngày tải lên :
10/08/2014, 18:20
... The extent of ulceration depends on the: Type of offending drug Amount of extravasated material Site of extravasation: more severe reactions tend to develop on the dorsum of the hand and in the ... healing mechanisms, including the induction of myofibroblast differentiation, the mobilization of white blood cells, and the stimulation of proliferation and migration of epithelial cells [32, 57] Perilesional ... Effects of Growth Factors 190 15.10 Summary and Future Research 190 References 190 The identification of topical growth factors and the development of their use in treating chronic ulcers of the skin...
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Wound Healing and Ulcers of the Skin - part 9 pdf
Ngày tải lên :
10/08/2014, 18:20
... mitosis of the germinal layer of the epidermis, hair follicles, and sweat glands [35] These were followed by other studies that demonstrated epidermal proliferation and enhancement of epithelialization ... be adjusted to the patient’s general condition, the patient’s weight, the presence of other diseases, the presence of infection, and the severity of ulcers 19.2.3 Supplementation of Amino Acids ... preparations and to identify their mode of action (if such exists) on the healing process In an article reviewing the beneficial effects of honey, published in the Journal of the Royal Society of Medicine...
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Wound Healing and Ulcers of the Skin - part 10 pdf
Ngày tải lên :
10/08/2014, 18:20
... from the ulcer’s surface [18] The rate of the drip should be adjusted to the level of hydration of the ulcer – the dryer the ulcer the faster the drip rate should be Frequent monitoring is mandatory ... caused by an imbalance of bacteria Surg Clin North Am 1997; 77 : 637–650 14 Winter GD: Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic ... distal areas are massaged to mobilize the fluid proximally The scheduling of therapeutic sessions depends on the size of the ulcer, the amount of edema, and the patient’s general condition It is...
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Báo cáo y học: "Two-dose-level confirmatory study of the pharmacokinetics and tolerability of everolimus in Chinese patients with advanced solid tumors" pps
Ngày tải lên :
10/08/2014, 21:23
... participated in the design of the study, carried out parts of the study, wrote the manuscript, and contributed equally to this study; LS and DY carried out parts of the study and contributed ... range, 42-153) For the patients still participating in the study at the time of data cutoff, everolimus exposures were 209 and 230 days for the patients with RCC and 243 days for the patient with ... before the first dose of everolimus (baseline), weekly for the first weeks, every other week for the second and third month, and monthly thereafter A safety follow-up was conducted 28 days after the...
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Báo cáo y học: "Neuroendocrine tumors of the gallbladder: a case report and review of the literature" docx
Ngày tải lên :
10/08/2014, 23:22
... suggestive of an NET tumor The determination of the histological type of the tumor and differential diagnosis from GB adenocarcinoma are often difficult The identification of neuroendocrine cells and the ... indicating the lack of metastases and the successful surgical treatment of a “typical” carcinoid of the GB Indeed, in one study, 82.4% of GB carcinoids remained localized and only 11.8% of patients ... differentiation, the tumor size, the absence of angioinvasion and infiltrative growth, and the immunohistochemical staining supported the final diagnosis of a “typical” rather than of an “atypical” NET tumor...
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