... angiitis ofthe central nervous system: serial MRI of brain and spinal cord Neuroradiology 2001, 43:599-607 14 Moore PM: Diagnosis and management of isolated angiitis ofthe central nervoussystem ... Angiitis ofthe Central Nervous System: a Case Report and Review CNS Spectrums 2008, 13:209-213 Page of 10 Ozawa T, Sasaki O, Sorimachi T, Tanaka R: Primary angiitis ofthe central nervous system: ... presentation of primary angiitis ofthe central nervoussystem Ann Rheum Dis 2008, 67:1732-1735 doi:10.1186/1477-7819-9-97 Cite this article as: You et al.: Isolated angiitis ofthe central nervous system...
... descends on the body, and the digestive system is more active The sympathetic output ofthenervoussystem originates out ofthe lateral horn ofthe thoracolumbar spinal cord An axon from one of these ... Divisions ofthe Autonomic NervousSystem Connections of Sympathetic Division ofthe Autonomic NervousSystem Neurons from the lateral horn ofthe spinal cord (preganglionic neurons) project to the ... Parasympathetic Division ofthe Autonomic NervousSystemThe parasympathetic division ofthe autonomic nervoussystem is named because its central neurons are located on either side ofthe thoracolumbar...
... that the lack of CCR5 does not protect from MS, but rather it may predispose to the chronic course ofthe disease [69] This would further imply that in view ofthe redundancy in the chemokine system, ... immunoneutralization of CCL3 [44], DNA vaccination [45], or genomic deletion ofthe CCR1 gene [22], reduces clinical disease Taken together, the results ofthe present study and from previous ones on the role of ... knock-out of CCR5 in humans per se confers no protection from MS, and the lack of effect of CCL3 deficiency in mice [67] illustrates redundancy in the chemokine system Although some ofthe data on the...
... vulnerable, population of patients Chemotherapy-induced cognitive decline in the absence of radiation The best data on the cognitive effects of chemotherapy alone have come from studies of children with ... certain brain tumors, especially for the very young Because ofthe rapid myelinization that occurs in infants, the finding by Noble and colleagues [1] ofthe adverse effects of chemotherapy on oligodendrocytes ... are planned that further reduce the dose of craniospinal radiation to 1,800 cGy, virtually no attention has been paid to the possible contribution ofthe chemotherapy to the cognitive decline...
... at the month time point, along with markedly decreased levels of MBP in the CC and in the white-matter tracts ofthe striatum of treated animals (Figure 10) In agreement with the majority ofthe ... nuclei; the distribution, morphology and size of these nuclei resembled those ofthe microvasculature endothelial cells ofthe CNS (Figure 11c-e) Double-labeling to visualize expression of Journal of ... contribute to the effects of chemotherapy on cognition The ability of irradiation to the CNS to suppress the generation of new neurons in the hippocampus has been suggested to be relevant to the understanding...
... is the first study of NOS expression in the goat brain with listeriosis The involvement of iNOS in bovine and caprine listeriosis has been reported previously, and the increased expression of ... Magnification A and B, ×66 C and D, ×132 Immunohistochmical study of nitric oxide synthase in the central nervoussystemof goat Enhanced expression of nNOS and iNOS in L monocytogenes-infected brain At ... were found in the neuronal processes Both nNOS and iNOS immunoreactivity were found in a proportion ofthe neurons in the brainstem and the staining pattern was similar to those of control brains...
... known that the nanoparticles will interact with the proteins present in the biological system, i.e the material surrounding the nanoparticles are proteins present in thenervoussystemofthe cockroach ... This correlation of activity and the effect ofthe nAuNPs on the CNS ofthe insect are due to how the brain ofthe cockroach controls its muscle response and locomotion [6] There is a significant ... in weather affect the activity of both groups The effects of these variables are diminished by presenting the activity ratio ofthe treated to the untreated group Although the treated/untreated...
... performed The surgical specimen included a bluish mass localized in the head ofthe pancreas Pathology and immunohistochemistry ofthe tumor revealed a SPT The postoperative course ofthe patient ... mass at the epigastrium, the left or the right hypochondrium [2] Furthermore, pain can also be the first sign of a SPT [2] To our knowledge, this is the first case where the first sign of SPT ... on the location ofthe tumor, represent the procedures of choice [2] The mean size of SPTs is 6.08 cm, so the tumor in this case is classified as small Conclusion In our case, the most noteworthy...
... common mechanisms of action of these drugs are the inhibition ofthe rate limiting steps of Aβ generation i.e β- and/or γ- secretases processing of APP (Citron, 2010) Although the reasoning behind ... of H2S measurement, it’s almost impossible to determine the active form of H2S (H2S, HS- or S2-) present in the biological system Hence the all-encompassing term of H2S is now used to refer the ... the neurons The research group detected the significant presence of H2S in the brain homogenate preparation of CBS-/- mice (Shibuya et al., 2009) Kimura further observed that 3-MST acts together...
... functions ofthe therapeutic genes 1.1.2 Non-viral and Viral Gene Delivery Systems Depending on the usage of vectors, there are two main types of gene delivery systems: non-viral and viral systems ... low efficiency of non-viral gene delivery remains a critical drawback ofthesystem On the other hand, viral gene delivery systems are favoured because ofthe high efficiency of infective viral ... member ofthe retrovirus family The main advantage of lentivirus-based vectors is their ability to integrate into the host genome of both dividing and nondividing cells, thereby providing the potential...
... nervoussystem 13 1.2.1 The expression of Rag genes in thenervoussystem 13 1.2.2 A brief overview ofthenervoussystem 16 1.2.3 Questions about the neuronal function of Rag1 17 1.3 Advantages of ... 2001) These data indicate that the expression of Rag1 in thenervoussystem is conserved among vertebrate species and suggest a function 1.2.2 A brief overview ofthenervoussystemThenervoussystem ... According to these functions, thenervoussystem is categorized as sensory system, integrating system and motor system respectively (Delcomyn, 1998) The structural organization ofthenervous system...
... one ofthe key issues of gene therapy The expression level and specificity ofthe therapeutic gene is primarily determined by the activity ofthe promoter at the transcriptional level, and the ... in thenervous system, carrying out the fundamental tasks of receiving, conducting and transmitting signals Therapeutic protection of these cells is one ofthe main goals of gene therapy of neurological ... issue of gene therapy The tropism ofthe vector can essentially determine the cell type-specificity ofthe transgene expression at the transductional level, and the transduction efficiency of the...
... help in the study ofthe role of EphrinB2 in vivo EphrinB2 expression has been detected in the visual system in other organisms The aim of this project was to study the expression pattern of EphrinB2 ... al., 1967) At least at the molecular level there seems to be a link between the immune system and thenervoussystem Rag1 plays a key role in the initiation of this process of genomic rearrangement ... With the help of mutants and other tools of genetic manipulation, the mechanisms of neural differentiation and nervoussystem patterning have been elucidated As proposed by Goodman and Doe, the...
... onto the cover glass beside the sticky tape, with the help of a second blunt needle The embryo was not lifted above the surface ofthe dissecting medium, as this caused dispersion ofthe tissue The ... and is the excitation intensity ofthe laser at the centre ofthe laser π wo beam with laser power P wo and zo are the radial and axial distances ofthe laser focus, respectively, at which the fluorescence ... introduction ofthe model organism, Drosophila melanogaster, is also given Chapter introduces the concepts and theory of FCS as well as the experimental setup of this instrument The calibration of the...
... might be useful to the understanding ofthe control of locomotion and pain responses The identification ofthe receptor(s), and the identification ofthe specific regions ofthe receptor(s) and ... performed uѕing the two pаirѕ of oligonucleotideѕ Ligаtion ofthe frаgmentѕ viа XmаI reѕtriction ѕite yielded the full-length ѕynthetic gene of 369 bp The ѕynthetic gene wаѕ cloned into the pGEMT-eаѕy ... 5A) The effect of pro-ohanin on the locomotor activity ofthe mice was examined via i.p injection at the doses of 0.1 mg/kg, mg/kg and 10 mg/kg The total movement counts of pro-ohanin at the...
... implement the process ofthe quality management systemofthe company based on the voluntary and self-control spirit The regular discussions among them will contribute to enhance the effectiveness of ... because they are people who directly implement, maintain and improve thesystemThe company should organize training-courses to raise the awareness of officials and workers about the effects ofthe ... management 2.1.3 The principle of quality management system There are eight quality management principles on which the quality management system standards ofthe ISO series are based These principles...
... practice There is a growing consensus that the current predominantly career based system in the Vietnamese civil service is one ofthe major causes ofthe shortcomings ofthesystemThe increasing ... patronage system to methods of merit selections; so that the most competent politically acceptable person gets the job In the longer term, the further strengthening ofthe principle of merit in the ... training of civil servant The definition of training was provided in the order (ukaz) No 983 ofthe President ofthe Russian Federation of September 1997 on “Complete methods for the training of State...
... evaluating the effect of failures in auxiliary electrical spstem on the reliability of a generating unit We would like t o note that the performance of auxiliary electrical system (and of other systems) ... units in the station Some ofthe buses can be supplied from the station common bus or thebuses of other units For this reason, the whole auxiliary electrical systemofthe stationwill have to be ... failures in other auxiliary systems The actual values of MWhr/yr not supplied due to the failures in auxiliary electrical system will be, therefore, less than those given in the paper The authors...
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