... expression and their replication A number of RNA cofactors have been discovered, which include specific nucleic acids binding proteins, chaperones and helicases [9-11] In that respect, RNA chaperones ... other nucleic acid based therapeutics for the treatment of chronic HCV Infect Disord Drug Targets 2006, 6:43-56 Bowen DG, Walker CM: Adaptive immune responses in acute andchronichepatitisC virus ... Supérieure, Lyon, France) summarized a decade of research dedicated to the nucleocapsid protein NC of HIV-1 In fact, NC is both a specific nucleic acid binding protein and a potent RNA chaperone that...
... provided by the same company Asymmetric primer was 5′-TGTCTCGTGTTACAGGCGGGGT-3', asymmetric primer was 5′-GAGGCATAGCAGCAGGA GAAGAG-3', and fluorescent primer was 5′-TCGCTGGAAGTGTCTGCGGCGT-3' Serum assays ... Impact of non-alcoholic fatty liver disease on chronichepatitis B Liver Int 2007; 27:607-611 Gordon A, McLean CA, Pedersen JS, et al Hepatic steatosis in chronichepatitis B and C: Predictors, ... contrary, it has to be recognized as a “co-factor” capable of affecting the gravity and progression and also therapeutic perspectives of liver diseases We compared the clinical and histological...
... B specific, antisense) 5'-GGT CCT AGG AAT CCT GAT GTT G-3' (nt 165–186, type C specific, antisense) 5'-GCC AAC AAG GTA GGA GCT-3' (nt 2979–2996, type D specific, sense) 5'-CAC CAG AAA TCC AGA ... 15.70% 2.90% 10% A Sequence a(position, specificity, and polarity) 25.70% B C D 5'-TCA CCA TAT TCT TGG GAA CAA GA-3' (nt 2823–2845, universal, sense) 5'-CGA ACC ACT GAA CAA ATG GC-3' (nt 685–704, universal, ... GGA CCA-3' (nt 2955–2978, type E specific, sense) 5'-GYT ACG GTC CAG GGT TAC CA-3' (nt 3032–3051, type F specific, sense) 5'-GGA GGC GGA TYT GCT GGC AA-3' (nt 3078–3097, types D to F specific,...
... B specific, antisense) 5'-GGT CCT AGG AAT CCT GAT GTT G-3' (nt 165–186, type C specific, antisense) 5'-GCC AAC AAG GTA GGA GCT-3' (nt 2979–2996, type D specific, sense) 5'-CAC CAG AAA TCC AGA ... 15.70% 2.90% 10% A Sequence a(position, specificity, and polarity) 25.70% B C D 5'-TCA CCA TAT TCT TGG GAA CAA GA-3' (nt 2823–2845, universal, sense) 5'-CGA ACC ACT GAA CAA ATG GC-3' (nt 685–704, universal, ... GGA CCA-3' (nt 2955–2978, type E specific, sense) 5'-GYT ACG GTC CAG GGT TAC CA-3' (nt 3032–3051, type F specific, sense) 5'-GGA GGC GGA TYT GCT GGC AA-3' (nt 3078–3097, types D to F specific,...
... (F2): 5'-GTGCAGCCTCCAGGACCC-3' Reverse (1TS): 5'-GCGACCCAACACTACTCGGCT-3' Both reactions were carried out in 50 μl volume and the mixture contained 0.2 mM from each dNTP, 10 μM of each primer, ... is chronically infected and infection is the main etiological agent of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma [2] Among the mechanisms the virus exerts to persist infection ... primers 1CH or 2CH for plus or minus strands respectively and the mixture was preheated at 92 C for 30 sec then chilled on ice The sequence of the primers used was as follows: 1CH : 5'GTGCACGGTCTACGAGACCTC-3'...
... hepatocellular carcinoma indicated the abdomen Magnetic resonance imaging scan ofby the arrow with a Magnetic resonance imaging scan of the abdomen with a hepatocellular carcinoma indicated by ... pancytopenia associated with viral hepatitis have occurred in the context of acute hepatitis rather than chronic infection, with bone marrow biopsy usually revealing a markedly hypocellular marrow ... immediately upon acceptance cited in PubMed and archived on PubMed Central yours — you keep the copyright BioMedcentral Submit your manuscript here: http://www.biomedcentral.com/info/publishing_adv.asp...
... result[10,11] And recently, some randomized controlled clinical trials compared the efficacy of LAM and LdT in the treatment of chronichepatitis B and had different results Thus, we conducted this ... systematic review of these trials to assess the evidence obtained on the efficacy of LdT treatment in chronic HBV infection Page of 11 decompensated liver disease, HIV, hepatocellular carcinoma, ... the searches(PUBMED:8; Web of Science:12; EMBASE:37; CNKI:42; VIP database:18; WANFANG database:33; the Cochrane Central Register of Controlled Trials and the Cochrane Database of Systematic Review:21)...
... Demographic and biochemical characteristics of 92 consecutive middle-aged and normal weight male subjects with chronichepatitis B are presented in Table Mean of serum HBV DNA, HDL and ALT level ... adiponectin in chronichepatitisCand B J Viral Hepat 2007, 14:577-583 10 Su TC, Lee YT, Cheng TJ, Chien HP, Wang JD: Chronichepatitis B virus infection and dyslipidemia J Formos Med Assoc 2004, 103:286-291 ... 2003, 17:1173-1178 24 Hsu CS, Liu CH, Liu CJ, Chen CL, Lai MY, Chen PJ, Chen DS, Kao JH: Factors affecting early viral load decline of Asian chronichepatitisC patients receiving pegylated interferon...
... protocols and to define specific criteria for the follow up of such patients Abbreviations HBV: Hepatitis B Virus; HCV: HepatitisC Virus; DNA: Desoxyribonucleic Acid; RNA: Ribonucleic Acid; HCC: ... F, Chemello L, Cecchetto A, Alberti A: Concurrent hepatitis B andC virus infection and risk of hepatocellular carcinoma in cirrhosis A prospective study Cancer 1994, 74:2442-2448 Chiaramonte M, ... Microbiol Antimicrob 2005, 4:13 31 Sagnelli E, Coppola N, Marrocco C, Onofrio M, Sagnelli C, Coviello G, Scolastico C, Filippini P: HepatitisC virus superinfection in hepatitis B virus chronic...
... 12 12 RCT RCT RCT RCT RCT RCT RCT RCT B C B B CC B C Abbreviations C: combination therapy; M: monotherapy; Tα1: thymosin alpha 1; LAM: lamivudine; w: weeks; m: months; RCT: randomized controlled ... sufficient for the eradication of a CHB infection Only a few randomized controlled clinical trials have been conducted to evaluate the efficacy of the combination of lamivudine and Tα1 in CHB ... chronichepatitis B Jilin Medicine 2005, 26:1059-1060 Zhao WL, Yang ZM, Liu HP, Hui G: Therapeutic Efficacy of Thymosinα1 Combined with Lamivudine on Patients with ChronicHepatitis B Practical...
... 12 12 RCT RCT RCT RCT RCT RCT RCT RCT B C B B CC B C Abbreviations C: combination therapy; M: monotherapy; Tα1: thymosin alpha 1; LAM: lamivudine; w: weeks; m: months; RCT: randomized controlled ... sufficient for the eradication of a CHB infection Only a few randomized controlled clinical trials have been conducted to evaluate the efficacy of the combination of lamivudine and Tα1 in CHB ... chronichepatitis B Jilin Medicine 2005, 26:1059-1060 Zhao WL, Yang ZM, Liu HP, Hui G: Therapeutic Efficacy of Thymosinα1 Combined with Lamivudine on Patients with ChronicHepatitis B Practical...
... Piazza M, Salvatore F, Sacchetti L: Multivariate discriminant function based on six biochemical markers in blood can predict the cirrhotic evolution of chronichepatitis Clin Chem 2001, 47:1696-1700 ... medicine and infectious diseases annual meetings Only publications or abstracts concerning FT-AT in chronichepatitisC were included Diagnostic value of FT-AT among published studies For each ... F, Thibault V, Bochet M, Charlotte F, Ratziu V, Bricaire F, Katlama C, Poynard T: Serum biochemical markers accurately predict liver fibrosis in HIV andhepatitisC virus-coinfected patients AIDS...
... immunodeficiency virus, andhepatitisC virus were negative The persistence of biochemical and virological abnormalities was an indication for a liver http://www.comparative-hepatology.com/content/7/1/3 ... approximately four- and six-fold less susceptible to tenofovir and entecavir therapy than wild type HBV This correlates with the clinical setting in which successful rescues with tenofovir or entecavir against ... chronichepatitis B who achieved a sustained virological and biochemical response to a second-line of combination therapy with lamivudine and adefovir despite the presence of rtM204V/ I, rtN236T, and...
... the effect of chronic HCV-infection, we repeated the analyses in subgroups defined by patients’ characteristics Speci c causes of death We computed the cumulative incidence of speci c causes of ... the CCI Three comorbidity levels were defined: none (CCI score = 0), medium (CCI score = 1–2) or high (CCI score > 2) Alcohol abuse and HIV infection Information on alcohol abuse and HIV infection ... level of comorbidity, we also observed no association between chronic vs cleared HCVinfection and mortality [27] These findings suggest that chronic HCV-infection, compared to cleared HCV-infection,...
... microcurrent therapy might change the concept of management of chronic disease Conclusively, oxida- 33 tive stress and oxidative damage to tissues are common pathology of chronic diseases, and ... and not only does this correct malalignments in the cells electrical system but it also eliminates free radicalsand then stimulates the mitochondria to produce ATP Microcurrent has been successfully ... abscess and accelerated wound healing (20) Substances that increase electrical field, such as prostaglandin E2, enhance the wound healing rate and increase cell division (26-28) Electrical fields...
... to management of CHB Clinical Presentation of Chronic HBV Infection As discussed by Drs Zhang and Pan in this special issue, the clinical presentation of chronic HBV infection can be quite different ... different ranging from inactive carrier status to HBV-cirrhosis or hepatocellular carcinoma (HCC) Understanding the spectrum and clinical presentation of chronic HBV infection is prerequisite for ... different stages of chronichepatitis B infection Hepatology 2002; 36:1408-1415 Yang LM, Xu KC, Zhao YL, Wu ZR, Chen TF, Qin ZY,et al Clinical significance of liver biopsy in chronichepatitis B patients...
... the physico-chemical processes, which was the mixture of the effluent from the phosphorus adsorption column and the backwash water, was circulated back to the anaerobic tank and the oxic tank at ... S and Hirata, A (2002b) Transformation of phosphorus and relevant intracellular compounds by a phosphorus-accumulating enrichment culture in the presence of both the electron acceptor and electron ... be ozonated and the recirculation ratio of the residual liquid from the physico-chemical processes to the anaerobic and oxic tanks Influent Effluent Anaerobic tank Oxic tank Anoxic tank Sludge...
... are conducive to physical activity? V.7 Socio-economic inequalities V.7.1 Food choice is determined by both individual preferences and socio-economic factors29 Social position, income and education ... Diet, Nutrition and the Prevention of Chronic Diseases, op cit Weight control and physical activity Lyon, International Agency for Research on Cancer, 2002 (IARC Handbooks of Cancer Prevention, ... of diet and physical activity Certain neighbourhoods could discourage physical activity, lack recreation facilities and affect the disadvantaged more than those who can afford or have access to...
... mutually adjusted Chronic bronchitis Chronic cough a PM10 Sample size NO2 PM10 1950 NO2 1902 Chronic cough with phlegm production PM10 NO2 Mild COPD PM10 1922 b NO2 Moderate COPD PM10 342 c NO2 342 Parameter ... (6.6%) N = 179 (5.6%) N = 163 (8.0%) Chronic Bronchitis by physician’s diagnosis Chronic cough a Chronic cough with phlegm production a a a Reported by participant Only in a subgroup that was invited ... prevalence of the age-related increase of chronic cough with and without phlegm production, as well as mild COPD Industrialized and rural areas might differ in some respects, which we did not account...
... Staphylococcus aureus; CF: cystic fibrosis; CI: confidence interval; CNS: coagulase-negative Staphylococci; COPD: chronic obstructive pulmonary disease; COX: cyclooxygenase; CRS: chronic rhinosinusitis; ... in antimicrobial prescribing and pneumococcal resistance, Canada, 1993-2005 46th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy San Francisco 2006 59 Green K, McGreer A, ... Misiolek H: Comparison of the efficacy and tolerability of amoxycillin/ clavulanic acid 875 mg b.i.d with cefuroxime 500 mg b.i.d in the treatment of chronicand acute exacerbation of chronic sinusitis...