radiation therapy alone or with chemotherapy or molecularly targeted therapy
Báo cáo khoa học: " Accelerated high-dose radiotherapy alone or combined with either concomitant or sequential chemotherapy; treatments of choice in patients with Non-Small Cell Lung Cancer" pps
... treated with Distant-metastasis free interval for 131 patients treated with accelerated high-dose radiotherapy with or without chemotherapy Figure with sequential chemotherapy or without chemotherapy ... treated with Local-recurrence free radiotherapy with or without chemoLocal-recurrence free interval for 131 patients treated with accelerated high-dose radiotherapy with or without chemotherapy for ... concomitant chemotherapy, with sequential chemotherapy or without chemotherapy patients treated with concurrent or sequential chemoradiation (27% and 23% respectively) than in patients treated with...
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In vitro and in vivo study of ABT 869 in treatment acute myeloid leukemia (AML) alone or in combination with chemotherapy or HDAC inhibitors insight into molecular mechanism and biologic characterization
... (AML) alone or in combination with chemotherapy or HDAC inhibitors: insight into molecular mechanism and biologic characterization Zhou Jianbiao (M.D Nanjing, M.sc National University of Singapore) ... USA and for giving your support I am grateful to the flexible and stimulating work environment you created Dr Hanry Yu, my co-supervisor for your gracious commitments, for supporting my works, especially ... pretreatment with ABT-869 would make subsequent chemotherapy less efficacious In agreement with our data, antagonism has been reported with pretreatment with CEP-701, another FLT3 inhibitor, followed...
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báo cáo khoa học: "Management of stage one and two-E gastric large B-cell lymphoma: chemotherapy alone or surgery followed by chemotherapy?" potx
... patients treated with chemotherapy alone was 76% [17] However, for bulky tumors, the advantage of chemotherapy is overshadowed by the potential for tumor bleeding and gastric perforation Most studies ... http://www.jhoonline.org/content/3/1/23 Page of Table 1: Characteristics of patients with localized and advanced primary gastric lymphoma treated with surgery followed by chemotherapy or chemotherapy alone ... Treated with Chemotherapy Alone or Surgery Followed by ChemotherapyJ Formos Med Assoc 2006, 105(3):194-202 20 de Jong D, Aleman BMP, Taal BG, Boot H: Controversies and consensus in the diagnosis, work-up...
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Báo cáo y học: "Infliximab in ankylosing spondylitis: alone or in combination with methotrexate? A pharmacokinetic comparative study" ppt
... regarding TNF-a antagonist therapy for patients with AS or psoriatic arthritis, the French Society for Rheumatology recommendations suggest that there is insufficient evidence for concomitant disease-modifying ... and Abbott Laboratories FL received compensation for travel, accommodations and meeting expenses from Abbott Laboratories and Servier DW is a board member for Pfizer; has grants or grants pending ... consultancies with Abbott Laboratories, BMS and Pfizer; received payment for lectures from Abbott Laboratories, BMS, MSD, Pfizer, Roche and Schering-Plough; and was compensated for travel, accommodations...
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Báo cáo y học: "Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation" ppt
... support was started with 100 J biphasic defibrillation attempt (M-Series Defibrillators, Zoll Medical Corporation, Chelmsford, Massachusetts, Page of 11 USA), all subsequent attempts were performed ... Wears RL, Weil MH: Utstein-style guidelines for uniform reporting of laboratory CPR research A statement for healthcare professionals from a task force of the American Heart Association, the American ... analysis was performed with a one-way analysis of variance (ANOVA) followed by a Bonferroni post hoc test to correct for multiple measurements RT-PCR data analysis was performed according to a relative...
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Báo cáo y học: " Patient Specification Quality Assurance for Glioblastoma Multiforme Brain Tumors Treated with Intensity Modulated Radiation Therapy"
... Glioblastoma multiforme (GBM) is the most frequently encountered and most malignant form of brain tumor, with a poor prognosis and low life expectancy [21] Intensity modulated radiation therapy (IMRT) ... Presently, we perform routine QA measurements for each IMRT patient either immediately prior to the treatment or shortly after the first treatment Table shows the total number of IMRT fields for the ten ... http://www.medsci.org Int J Med Sci 2011, The software is MatrixScan (PTW-Verisoft 3.1) which records the measurements with the 2D-ARRAY Prior to the treatment the temperature, pressure, and a correction factor...
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Báo cáo khoa học: "Supracricoid partial laryngectomy with cricohyoidoepiglottopexy in patients with radiation therapy failure" ppsx
... Negative 2 2 1 AwoD, Alive without disease; LwoD, Lost without disease; AwD, Alive with disease; RT, radiation therapy Page of (page number not for citation purposes) World Journal of Surgical ... alter failure of radiation therapy Eur Arch Otorhinolaryngol 2007, 264:809-14 Clark J, Morgan G, Veness M, Dalton C, Kalnins I: Salvage with supracrioid partial laryngectomy after radiation failure ... Finally, organ preservation in this series was 75% with local control being 87%, similar to other reports (Table 4) [11,16,18] In conclusion, in selected patient with persistence and /or recurrence...
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Báo cáo khoa học: " SemiNeo-adjuvant chemo-radiation of rectal cancer with Volumetric Modulated Arc Therapy: summary of technical and dosimetric features and early clinical experience" ppsx
... rate observed for patients treated with RA is consistent with reported data [3] The possibility of improving organs at risk sparing shall be explored with RA in order to compensate or mitigate known ... encouraging for further experience in this field In summary, twenty-five patients with advanced rectal cancer were treated preoperatively within and neoadjuvant radio -chemotherapy scheme with radiation ... Conformal shaping of the fields was performed by means of static MLC Plans were computed for a Clinac 2100EX equipped with a MLC-80 (80 leaves with a resolution at isocentre of 10 mm) and for...
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Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot
... [7,26,29-31] It also has been reported [27,31] that chemotherapy, particularly when combined with thoracic radiation therapy, was associated with an increased risk for radiation pneumonitis However, ... diabetes history, induction chemotherapy, concurrent chemotherapy regimens and PS) of patients with and without SARP Several reports [7,9,11,14,15,19] showed that some dosimetric factors are likely ... conventional or conformal radiotherapy [15,19] Perhaps this is because we applied IMRT techniques, which had high conformity and spared more normal lung from irradiation, and therefore may have...
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Báo cáo khoa học: "Postmastectomy irradiation in breast in breast cancer patients with T1-2 and 1-3 positive axillary lymph nodes: Is there a role for radiation therapy" ppsx
... radiotherapy and no-radiotherapy group Radiotherapy Group Radiotherapy n = 66 NoRadiotherapy n = 24 n % n % 1.5 P Local-regional recurrence Chest wall alone No Radiotherapy Peripheral lymphatics alone ... respectively [7] Similarly, Overgaard et al reports a 114-month rate of LRR alone of 26% for women given chemotherapy without RT and 5% for those given both chemotherapy and RT [3] During recent decades, ... of them have one or more predictor and prognostic factors for failure It appears that the benefit of RT is worth of the risk of treatment morbidity with accurate selection PMRT for T1-2 and N1-3...
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Báo cáo khoa học: "Clinical Analysis of stereotactic body radiation therapy using extracranial gamma knife for patients with mainly bulky inoperable early stage non-small cell lung carcinoma" pot
... patients with chemotherapy was 3.659 times higher than that of the patients without chemotherapy (p = 0.042) In these 13 patients receiving chemotherapy, the number of cases with tumor size ≤ ... was found that tumor centre or periphery BED was important parameter influencing local tumor control rate and larger doses should be delivered for T2 tumor Therefore, more works needs to be done ... local control rates were 75% and 60% for tumor ≤3 cm; 84% and 71% for tumor sized 3~5 cm; 55% and 14.6% for tumor sized 5~7 cm; and 45%, 21% in those with tumor size of >7 cm (Figure 2) 25 patients...
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Báo cáo khoa học: " Monte Carlo dose verification of prostate patients treated with simultaneous integrated boost intensity modulated radiation therapy" ppsx
... were higher for the majority of the patients (14 out of 22) for the rectum The deviations between SC and MC computed dose-volume indices for bladder and rectum were within 3% for the majority of ... were
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Báo cáo khoa học: " Comparison of CT and integrated PET-CT based radiation therapy planning in patients with malignant pleural mesothelioma" pot
... recent report Plathow et al analyzed 54 patients with stage II and III MPM, and the authors reported accuracy of 77% for CT, 86% for PET, 80% for Magnetic Resonance Imaging (MRI), and 100% for PET-CT ... patients with a dose of 40 Gy in 20 fractions with and without chemotherapy and they informed that all of patients experienced radiation induced pulmonary fibrosis [29] However, in this setting, more ... Thirteen patients with histological diagnosis of MPM who were not candidate for a curative resection due to medical reasons or self refusal those who were treated with thorasic irradiation with a palliative...
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Báo cáo khoa học: " Radiation therapy planning with photons and protons for early and advanced breast cancer: an overview" ppt
... risk for long-term morbidity [34] Moreover, modern systemic adjuvant treatments, such as anthracycline-based chemotherapy, with or without taxanes, or trastuzumab [35], are associated with cardiotoxicity ... fall-off for beams that are conformed without external apertures Furthermore, quality assurance is a more complex process for dynamic systems External apertures, compensators and modulator wheels ... brachytherapy using interstitial implantation [41,43-45] or a balloon catheter (MammoSite Radiation Therapy System; Cytyc Corp Alpharetta, GA, USA) [46], 3D external beam conformal radiation therapy...
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Báo cáo khoa học: " Absence of toxicity with hypofractionated 3-dimensional radiation therapy for inoperable, early stage non-small cell lung cancer" pot
... decrease inspiratory motion or to deliver radiation in fixed phases of the breathing cycle However, we carefully monitored the tumor motion of our patients with fluoroscopy or electronic portal images ... were ordered only for patients with a suspicious sign or symptom of distant metastases The optimal accelerated regimen of conformal 3-dimensional hypofractionated radiation therapy (3DHRT) for ... 17 cases (53%) or fields in 13 (41%) cases Although less conformal, we preferred using or fields to avoid irradiating more normal lung and to facilitate monitoring the respiratory motion The...
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Báo cáo khoa học: " Comparing two strategies of dynamic intensity modulated radiation therapy (dIMRT) with 3-dimensional conformal radiation therapy (3DCRT) in the hypofractionated treatment of high-risk prostate cancer" doc
... arm for this dosimetric study For the anterior/posterior fields the superior border was at L5-S1, lateral borders cm lateral to the widest point of the bony pelvic inlet, and inferior border ... concurrent, and /or adjuvant form with the radiation [3,4] Unfortunately, the use of conventionally planned whole pelvic radiotherapy to treat the whole pelvis results in toxicity to normal structures ... on CT images For the lateral fields, the anterior border was the anterior surface of the pubic symphysis, posterior border was the middle of the sacrum, including at least a posterior 0.75 cm margin...
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báo cáo khoa học: "Successful treatment of a T4 lung tumor with vertebral body invasion using fiducial markers in the thoracic spine for image-guided radiation therapy: A case report" pps
... or paraspinal tumors who are not candidates for radiosurgery because of tumor factors such as large tumor size or other clinical reasons (such as indications for concurrent chemotherapy) may benefit ... evaluated by an orthopedic surgeon (JH) for implantation of fiducial markers for IGRT because of the proximity of the tumor to the spinal cord Markers were placed in the operating room with fluoroscopic ... treatment of a T4 lung tumor with vertebral body invasion using fiducial markers in the thoracic spine for image-guided radiation therapy: A case report Journal of Medical Case Reports 2011 5:470 ...
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báo cáo khoa học: "Successful treatment of a free-moving abdominal mass with radiation therapy guided by conebeam computed tomography: a case report" potx
... is a major problem in treating abdominal tumors with radiation therapy Tumors attached to the mesentery can move significantly more than tumors located in the retroperitoneal region Before the ... posteroanterior) such that the tumor was contained within the radiation port Because the extent of tumor motion ranged between and cm in all three dimensions and Dabaja et al Journal of Medical Case Reports ... on Radiation Units and Measurements (ICRU Report 62): Prescribing, recording, and reporting photon beam therapy (supplement to ICRU Report no.50) Bethesda, MD 1999 International Commission on Radiation...
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Báo cáo y học: "Treatment of eccrine porocarcinoma with metastasis to the parotid gland using intensity-modulated radiation therapy: a case report" pptx
... treated with surgery alone and 46% for those treated with radiation alone [8] In a more recent study, Weber and colleagues further confirmed the value of a dual approach of surgery and radiation therapy ... report, four cases of pediatric EPC were treated with a combination of 5-fluorouracil, doxorubicin and cyclophosphamide No response was observed after one year of therapy [17] In general, chemotherapy, ... reserved for metastatic EPC On the other hand, the role of radiation therapy in EPC seems to have changed over the years from radioresistance in earlier reports [15] to good local control in more recent...
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Modern Practices in Radiation Therapy Edited by Gopishankar Natanasabapathi pdf
... several months of chemotherapy followed by – weeks of radiation therapy concurrent with radiation sensitizing chemotherapy, followed by a - week therapy break prior to surgery This chemoradiation regimen ... because of regional factors such as tumor involvement of the superior mesenteric vein or portal vein, or tumor abutment/encasement of the superior mesenteric artery or celiac trunk or gastroduodenal ... the STAT RAD workflow even more efficient 4.1 Technologic rationale for the choice of the TomoTherapy platform The TomoTherapy platform has been chosen for the STAT RAD workflow for a variety...
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