... a-peptides (oligomers of a-amino acids) has recently been applied to the syntheses of linear tetrapeptides of somatostatin [20] and of cyclic tetrapeptide and pentapeptide analogues of the RGD sequence ... addition of a backbone methylene group could have minor effects on the overall conformation and biological activity of the peptide Thus, SP was used as a model peptide to analyse the structural and biological ... structures of the b-amino acids that best fit are shown in Fig They all correspond to gauche(+) values of the h angle The methyl group of b2-HAla occupies a position close to that of CH2b of Pro or...
... ecosystemic effects and the ecological role of pollutants is accumulation of knowledge of the biologicaleffectsof these substances on particular species 1.3 BiologicalEffectsof Substances ... 1:41 AM BIOLOGICALEFFECTSOF SURFACTANTS expansion and improvement of the arsenal of biotesting methods (Filenko 1988; Flerov 1989), as well as the need for more detailed studies of the biological ... Friday, November 11, 2005 1:41 AM BIOLOGICALEFFECTSOF SURFACTANTS The problems of assessing the biological activity of substances are related to many aspects of ecotoxicology (Dmitrieva 1976;...
... field of water quality studies (Unified methods for water quality studies Part Methods ofBiological Analysis of Waters, ed by M Gubachek, Moscow, 1975) They are used in the arsenal of methods of ... The group of methods for estimating the biological activity of substances and pollution of aqueous medium by their effect on the elongation of preincubated seedlings When the effect of a tested ... group of methods for estimating the biological activity of substances and pollution of aqueous medium by their effect on the mean length of seedlings Some substances can slow down elongation of...
... 1:42 AM BIOLOGICALEFFECTSOF SURFACTANTS 173 Table 6.30 Effect of sublethal concentrations of AHC on Mytilus galloprovincialis Concentration of AHC, mg/l 25 Biologicaleffects Inhibition of filtration ... degree of inhibition of the seedlings correspondingly increased The problems of the quantitative comparison of the results ofbiological testing of different chemicals on the same species of test ... effect on the efficiency of removal of suspension from water Table 6.21 Effect of detergent Lanza (20 mg/l) on the change of OD550 of a suspension of S cerevisiae in the course of its filtration by...
... role of the processes related to water filtration: the processes of formation of certain transparency of water, which is important for the penetration of UV radiation and realization of the biological ... November 10, 2005 8:52 PM BIOLOGICALEFFECTSOF SURFACTANTS 189 1989, 1990) using the method of delayed fluorescence tested in studies of the biologicaleffectsof many pollutants (Matorin 1993) ... abundance, rates of growth, and nutrition of hydrobionts (Monakov 1998), and rates of excretion of pellets of faeces and pseudofaeces (Palaski and Booth 1995), and changes in the ratio of species in...
... part of ATP synthase not change in the presence or absence of D2O [14] However, the kinetics of F0 rotation in D2O were not examined Biologicaleffectsof deuteronation The dissociation of a ... is a part of the "rotor" In E coli, there is an aspartic acid residue in the middle of the second helix of subunit c Subunit a of F0 binds to the outside of the rotor and forms part of the "stator" ... the stator charge of Arg210 on subunit a A temporary stutter of the rotor is expected during the passage of deuteron *The ratio of deuterons (D+) to protons (H+) is ~1:15000 Page of (page number...
... TARGETS OF PLANT BIOACTIVE COMPOUNDS A pharmacological reference guide to sites of action and biologicaleffects GIDEON POLYA CRC P R E S S Boca Raton London New York Washington, D.C Library of Congress ... kill plant-consuming organisms 1.3 Description of the tables Most of the book is comprised of tables dedicated to specific targets or groups of targets of plant defensive compounds Target-related ... per litre) Of course, the quarltitation of such affinities depends upon the conditions of measurement and the source of the biochemical target entity However, it was felt that provision of such...
... president of the National Academy of Sciences The National Academy of Engineering was established in 1964, under the charter of the National Academy of Sciences, as a parallel organization of outstanding ... organize a workshop of national and inter national experts to identify research needs and gaps in knowledge ofbiologicaleffects and adverse health outcomes of exposure to radiofrequency (RF) energy ... number of other areas of toxicology in which knowledge is needed to support a complete evaluation of the possible health effectsof RF exposure; these gaps are identified in the body of the report...
... of thoracic vertebrae Absence of ribs Fusion of ribs Bifurcation of ribs Shortening of ribs Displasia of sternebrae Missing of sternebrae Hypoplasia of sternebrae Curvature of tibia Absence of ... development of brain, skull and extremities 10 11 12 13 14 15 16 17 18 References Beir, V Health effectsof exposure to low levels of ionizing radiationBiologicaleffectsof ionizing radiations ... effect of selenium against ionizing radiation- induced malformations in mice Acta Radiol Oncol 1985, 24, 267-271 Committee on the biologicaleffectsofradiation The effects on populations of exposure...
... V Health effectsof exposure to low levels of ionizing radiationBiologicaleffectsof ionizing radiations Washington, National Academy Press, 1990 Brent, R D The effectsof ionizing radiation, ... Fusion of thoracic vertebrae Absence of ribs Fusion of ribs Wavy ribs Hypoplasia of ribs Displasia of sternebrae Missing of sternebrae Hypoplasia of sternebrae Curvature of tibia Absence of metatarsal ... Radiol Oncol 1985, 24, 267-271 Committee on the biologicaleffectsofradiation The effects on populations of exposure to low levels of ionizing radiation, p 480, National Academy Press, Washington,...
... useful irradiation sensitizer in gastric cancer therapy Guidelines of the NCCN on gastric cancer Figure Quantification of mRNA expression of different genes Analysis of mRNA expression of COX-2, ... the downregulation of gene expression caused by irradiation These results clearly suggested that treatment with propranolol significantly improved the biological effect of irradiation and down ... regulated expression of the Figure Dose-survival curves of BGC-823 and SGC-7901 cells after different doses ofradiation with or without propranolol (50 μmol/L) 24 hr before irradiation Propranolol...
... anti-neoplastic effectsof the combined treatment were mainly due to the effectsof ionizing radiation (Figure 5C) Only when using a toxic concentration of ErPC3 (50µM), the combination of drug treatment ... down-regulation of p-Akt may be required for the anti-neoplastic action of small molecule inhibitors of the PI3K/Akt pathway in prostate cancer cells Combined effectsof ErPC3 and ionizing radiation ... underestimation of an apoptosis-based cytotoxic drug effect In LNCaP cells, the major part of the combination effects seemed to be based on the radiationeffects at least when non-toxic concentrations of...
... Gaber et al.: Effectsofradiation therapy on tissue and serum concentrations of tumour associated trypsin inhibitor and their prognostic significance in rectal cancer patients Radiation Oncology ... al Radiation Oncology 2011, 6:100 http://www.ro-journal.com/content/6/1/100 Page of 10 Figure Prognostic value of TATI concentrations in tumour tissue and serum ROC curves showing estimations of ... further supports the potential utility of TATI as a prognostic biomarker in patients with cancer of the colon and rectum, irrespective of neoadjuvant RT Page of 10 Additional material Additional...
... Furthermore, consumption of crude oil has also increased, with the average rate of increase of 6% per year in the past decades Part of this increase is the result of the growing use of motor vehicles, ... many of these chemicals, particularly over long periods of time at low exposure levels, is largely unknown One of the most widely known episodes related to disposal of hazardous wastes is that of ... will reach more than 80% of U.S output by 2025.5 An often-debated question is the impact of increased CO2 levels on vegetation Some laboratory studies indicate that the rise of CO2 levels in the...
... immediate area and causing 237 cases of acute radiation sickness.8 The explosion sent a devastating cloud ofradiation across a wide swath of Europe Radioactive forms of iodine, cesium, strontium, and ... in the city of Poza Rica, Mexico, in the early morning of November 24, 1950, was caused by the accidental release of H2S from a natural gas plant At the time of the accident, most of the nearby ... low concentrations of toxicants Signs and symptoms vary depending on the types of toxicants, their concentrations, and species of exposed organisms 3.7.2 ACUTE EFFECTS A number of acute pollution...
... acute injury occurs following absorption of sufficient amounts of toxic gas or other forms of toxicants to cause destruction of tissues The destruction is often manifested by collapsed leaf margins ... caused by uptake of sublethal amounts of toxicants over a long period Chronic injury is manifested by yellowing of leaves that may progress slowly through stages of bleaching until most of the chlorophyll ... Toxic Action of Pollutants 53 Similarly, high levels of O3 can induce peroxidation of the polyunsaturated fatty acids in the lipid portion of membranes, resulting in disruption of membrane structure.6...
... cells of the skin, the cells lining the gastrointestinal tract or those of the alveoli in the lung The passage of a compound across one of these membranes is therefore an FIGURE 7.4 Arrangement of ... and is mostly water Out of some 200 l of filtrate a day, an average adult concentrates about 1.5 l of urine It is obviously essential that most of the filtrate and many of its dissolved materials ... particulates is contraction of the muscles, causing the lumena of bronchi to be narrowed This results in removal of solid particulate matter with a diameter above mm, and permits less of the particulate...
... inhibition of lipid biosynthesis, oxidation of unsaturated fatty acids in vivo, and stimulation of peroxidase activity 8.3.4 HEALTH EFFECTS Studies on the pathological and physiological effects of NO2 ... Oxidants Committee on Medical and Biologic Effectsof Environmental Pollutants National Academy of Sciences, 1977 8.4.3 EFFECTS ON PLANTS Studies on the effects of O3 on higher plants are extensive ... response is termed adaptation.47 8.4.5 BIOLOGICALEFFECTS A large volume of literature has been published describing the biochemical effects of O3 Examples of the reported effects include: ...