r l stine the haunting hour afraid of clowns
Who’s Afraid of ID, A Survey of the Intelligent Design Movement
... the marks of nonhuman (alien, artificially intelli-gent, or supernatural) design (Ratzsch 2001, 118–20). This is the premise of the Search for Extra Terrestrial Intelligence (SETI), of research ... supposing that the complete history of a football team starts with the moment that the coach gathers together the players, thereby ignoring the important work the players had alreadydone. Before Johnson ... practice. For Rea, the problem is that naturalism can-not explain the modal qualities of particular physical objects. For Koons, the problem is that naturalism cannot account for the reliability...
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Tài liệu Báo cáo khoa học: Enzymes for the NADPH-dependent reduction of dihydroxyacetone and D-glyceraldehyde and L-glyceraldehyde in the mould Hypocrea jecorina doc
... heterologous host. The encoded proteins were purified and their kineticproperties characterized. GLD1 catalyses the conversion of d-glyceralde-hyde and l- glyceraldehyde to glycerol, whereas GLD2 ... activitywith C5 or C6 sugars. We tested d-glyceraldehyde and l- glyceraldehyde individually and observed similaractivities; the activity with l- glyceraldehyde was onlyslightly lower. For d-glyceraldehyde ... enzymes were purified andcharacterized. We show that one enzyme catalyses the reduction of d-glyceraldehyde and l- glyceraldehyde toglycerol, whereas the other reduces DHA. This is the first report on...
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Báo cáo khoa học: Crystal structure of salt-tolerant glutaminase from Micrococcus luteus K-3 in the presence and absence of its product L-glutamate and its activator Tris pdf
... few other short stretches, the structures were allvery similar over the entire polypeptide chain. However, the presence of the ligands significantly reduced the length of the disordered regions: ... site residues (including Arg223 and Ser227),either directly or indirectly. Similarly, the 33 orderedresidues in the T structure (that are disordered in the N form) are not related to the Tris-binding ... unified set of procedure for evaluating the quality of macromolecular structure-factor data andtheir agreement with atomic model. Acta Crystallogr DBiol Crystallogr 55, 191–205.42 Krissinel E &...
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Báo cáo khoa học: Characterization of a cathepsin L-associated protein in Artemia and its relationship to the FAS-I family of cell adhesion proteins pot
... found in the cyto-plasm a nd extracellular matrix where they may haveregulatory functions, unlike in somatic cells of multicellularorganisms where these enzymes are primarily lysosomaland thought ... represent the pI values of the major bands in e and f, while the numbers at the left are the pI values of standard proteins. The arrow at the right represents the pI value of 6.84 calculated for ... Biological Sciences, University of Windsor, Windsor, Ontario, Canada;2Department of Molecular Cell Biology,Sylvius Laboratory, Leiden, the NetherlandsWe reported previously that the major cysteine...
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Báo cáo khoa học: Structural basis for the erythro-stereospecificity of the L-arginine oxygenase VioC in viomycin biosynthesis docx
... b-strand (A) parallel to the first b-strand, B, of the jelly roll core. The linkage of the fourth (E) and fifth (F) b-strand of the jelly rollfold is built up by an extended insert (Val199–Leu296)consisting ... auto-mated program for molecular replacement. J ApplCrystallogr 30, 1022–1025.38 Emsley P & Cowtan K (2004) Coot: model-buildingtools for molecular graphics. Acta Crystallogr D BiolCrystallogr ... form a hydrogen bond and saltbridge with the a-amino group, although the carboxylgroup of Glu170 also coordinates the catalytic iron.Furthermore, the carboxyl group of l- arginine forms asalt...
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Báo cáo khoa học: NMR studies on the interaction of sugars with the C-terminal domain of an R-type lectin from the earthworm Lumbricus terrestris pot
... sugar-binding site because of the num-ber of intermolecular hydrogen bonds and of residuesinteracting with lactose. Our results agreed well withthose from the crystal structure of the complexbetween ... 6108–6117.53 Koradi R, Billeter M & Wu¨thrich K (1996) MOLMOL:a program for display and analysis of macromoleculestructures. J Mol Graphics 14, 51–55.Supporting information The following supplementary ... aggregates of glycopro-tein and glycolipid receptors. Thus, the carbohydratecross-linking properties of lectins are a key feature of their biological activities [30,43,44]. R- type lectins arereported...
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OMB Report Pursuant to the Sequestration Transparency Act of 2012 (P. L. 112–155) potx
... this report include those funding as sequestrable discretionary resources. That is because the STA requires for purposes of this report that OMB assume all discretionary appropriations are repeated ... 251A(5), the total reduction of $54.667 billion is allocated pro-portionately between discretionary appropriations and direct spending. The total base is the sum of the FY 2013 revised discretionary ... and classifications in the report are preliminary. If the sequestration were to occur, the actual results would differ based on changes in law and ongoing legal, budgetary, and technical analysis....
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Báo cáo khoa học: Identification in the yeast Pichia stipitis of the first L-rhamnose-1-dehydrogenase gene docx
... harvested before the sugarswere utilized, and the crude cell extract was analyzedfor l- rhamnose dehydrogenase activity. Cells grown on l- rhamnose as a sole carbon source had an l- rhamnosedehydrogenase ... Marechal LR & Veiga LA(1979) Induction and catabolite repression of L- rham-nose dehydrogenase in Pullularia pullulans. J Bacteriol138, 55–59.12 Jeffries TW, Grigoriev IV, Grimwood J, Laplaza ... fractions of plant biomass, such ashemicellulose and pectin. Several microorganisms liv-ing on decaying plant material are able to use l- rham-nose as a source of carbon and energy. There are...
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Báo cáo khoa học: Kininogen-derived peptides for investigating the putative vasoactive properties of human cathepsins K and L docx
... of extracellular CPmay be favored by the increased expression of vacuolar-typeH+-ATPase components, which reduces the pH of the pericellular environment of macrophages [20]. This raises the ... France).Na-benzoyl- L -arginine-4-nitroanilide ( L -BAPA) was fromMerck KgaA (Darmstadt, Germany). E-64 and phenyl-methanesulfonylfluoride were from Sigma-Aldrich (StQuentin le Fallavier, France). Molecular ... National Institute of Health grant, AR46182. C. D. holds a doctoral fellowship fromMENRT (Ministe`re de l Education Nationale, de la Recherche et de laTechnologie, France).References1. Mu¨ller-Esterl,...
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