... design, interpreted the data and drafted the manuscript OB gathered the data, interpreted the data and helped in drafting the manuscript AHR gathered the data and helped in drafting the manuscript ... by the Editor -in- Chief of this journal Inthe case of patient who died, consent for publication was sought from his next of kin Competing interests The authors declare that they have no competing ... needle inthe mediastinum The patient could not remember having swallowed the needle Since no part ofthe needle could be reached through endoscopy, the patient was scheduled for surgery Choosing...
... all ofthe expensive installation cost However, they have gradually increased the proportion ofthe installation cost sharing This is because the people were involved from the beginning ofthe installation ... 40% ofthe people interviewed were suffered from overflow ofthe latrine or the bad smell ofthe latrine, and about 30% had the feeling thatthe latrine was in dirty condition After 1999, the ... because ofthe number ofthe people using latrine increased because ofthe growth ofthe people living inthe same plots than testing period This means that there is a possibility to improve the...
... using weighted observations in GLIMMIX, the result is independent ofthe scale ofthe weights Terms were included inthe statistical models if they reduced the AIC value (Akaike 1985) Tests of ... p=0.10) The size of litters conceived inthe laboratory was also related to Breeding performance ofthe overwintered generation Frequency and timing of breeding inthe lab Inthe laboratory as inthe ... inthe laboratory, each observation was weighted with the inverse ofthe estimated probability of survival inthe estimation (see Littell et al 1996) Hence, the sum of weightings of animals of...
... estimates into the future to meet the reporting requirements In Table 1.1 we break down the process of estimating the savings into a series of steps The first step is to define the set of services ... formulating the scope of this work; David McNicol of OSD/PA&E for his insightful comments at the 2002 Western Economics Association Meetings in Seattle; and the members ofthe Office ofthe Secretary of ... of progress toward meeting the following year’s savings goals Introduction the current year and inthe following year inthe absence of any improvements inthe management of services procurement...
... inthe E1 state Mg2+ is ligated by residues inthe hinge motif inthe P domain and by residues inthe N domain, whereas inthe E2 state the latter are replaced by residues inthe TGES motif of ... dephosphorylation The latter observation, taken together with the likely location ofthe HP motif inthe N domain, might indicate that these mutants have a defect in nucleotide binding In order the phosphorylation ... rate inthe absence of ADP (A) and inthe presence of 250 lM ADP (B) Experimental conditions as in Fig located in a sequence that connects the putative metal binding site inthe TM domain to the...
... adiabatic interaction ofthe electromagnetic wave We insert the expression of nn ,l , p (t ) into the r r expression of j (t ) and then insert the expression of j (t ) into the expression of α in Eq.(4) ... expressions ofthe nonlinear absorption coefficient of a strong EMW by confined electrons in RQWs with infinite potential (Eq.9 and Eq.10), we see thatthe dependence ofthe nonlinear absorption ... that when the term in proportional to quadratic the intensity ofthe EMW ( E0 ) (in the expressions ofthe nonlinear absorption coefficient of a strong EMW) tend toward zero, the nonlinear result...
... Willis argued thatthe human soul/ mind was located inthe brain, and thatthe nerves, running from the brain to the rest ofthe body were responsible for all ofthe body’s functions including sensation, ... by the middle ofthe eight- Defining Nervous Disease in Eighteenth-Century Britain 15 eenth century was further facilitated by the new generation of physicians joining the faculty ofthe Edinburgh ... human reason in discovering the structure and inner workings ofthe nerves For instance, in his New Essay on the Nerves and the Doctrine ofthe Animal Spirits (1737), the physician David Kinneir expressed...
... inthe North, and thatthe rate of female entrepreneurship inthe micro sector is higher inthe more industrialised States ofthe South (36%) than inthe North (23%) This suggests that many of ... records the highest increase in Gini inequality (along with the South-West) Apart from the NorthCentral and North-West, the data suggest that income inequality has increased overall since democratisation ... group of middle-income countries (including India, China, Pakistan and Indonesia) that have large numbers of poor people Between them, these countries contain two thirds or 850 million ofthe world’s...
... part of an on-going investigation into the regulation of protein synthesis in mammalian cells, we have investigated the effects of inhibition ofthe proteasome on the localization and integrity of ... playing a role inthe migration of endothelial cells and in recovery of cells from wounding [40] In a variety of cells, in addition to the induction of hsp25 and aB-crystallin expression, inhibition ... of MG132 To measure the rate of protein synthesis, cells were incubated with 10 lCiÆmL)1 [35S]methionine during the last 15 min, solubilized in 0.3 M NaOH and incorporation of radioactivity into...
... before the beginning of each experiment They were then divided into three groups, one maintained at 24 °C and the other two exposed to cold (6 °C) for either two or 10 days The fat pads along the ... cells and induced the expression of UCP1 in some of them in both WT and b3KO mice Mice maintained singly housed at 24 °C are under a mild cold stimulus It is interesting to note inthe WAT of C57 ... 1.1% ofthe total adipocytes was multilocular The effects ofthe lack of b3-adrenoceptor were striking In mice kept at 24 °C, the density of multilocular cells was 36-fold (P < 0.01) lower in the...
... begins, complex cases being flown to up in most ofthe major centres in South Africa, and also a few in mentor institutions Africa, including in Egypt and Uganda However, while this phase of ... local infrastructure through teams PASCAR meeting in Nairobi in 2007 There are also many models There is no point in training a surgeon who has no local infrastruc- of different approaches being ... needs to be promoted for the sake ofthe millions who already an issue for Africans seeking training have crippling RHD in Africa An example of coordinated training is the Namibian Heart Project:...
... target of opening 35,000 rooms (excluding Motel 6) in 2012 Ofthe new rooms, 48% were opened inthe Asia-Pacific region, 28% in Europe, 14% in Latin America and 10% in Africa/Middle East The expansion ... dynamic of existing hotels in Europe Fast organic growth in emerging markets The strategic acquisitions of Mirvac in Australia/New Zealand and of Grupo Posadas’ hotels in Latin America Accor therefore ... primarily as a result of gains inthe Australian dollar and the British pound against the euro At constant scope of consolidation and exchange rates, the increase was 2.5% for the quarter Upscale...
... arbitrary power, as Madison noted in Federalist 47 In arguing for the necessity of separate institutions sharing power, Madison observed, quoting from Montesquieu, "Were the power of judging joined ... the parties need not have any particular knowledge ofthe principles; indeed, they might even misunderstand them The principles still apply to the terms of their agreement My thesis is thatthe ... rather "for the good ofthe Nation."111 In a constitutional state political power must be utilized inthe public interest Following the distinction between absolute and arbitrary power, the principle...
... the enzyme and is increased by the binding of PLP and substrates Indeed, the two helices that form the cluster interact with the N-terminal a-helix ofthe other subunit inthe dimer and are contiguous ... with the phosphorus atom depicted in orange, the oxygen atoms in red and the nitrogen atoms in blue The helices forming the third cluster interact with the N-terminal helix ofthe other subunit in ... obtained from the global nonlinear least squares fitting of internal aldimine and activity data to Eqns (1,2) cofactor is bound to the enzyme as internal aldimine, indicating thatthe loss of activity...
... Identi®cation of a speci®c amino acid cluster inthe calmodulin binding domain of nNOS FEBS Lett 403, 75 51 For the sequences of various NOS enzymes together with the positions ofthe binding domains ofthe ... (one of which mirrors part ofthe sequence ofthe calmodulin binding site of rat nNOS) preferentially interact with Ca2+calmodulin, impeding the interaction of Ca2+calmodulin with its binding ... citropin 1.1, frenatin 3, and caerin 1.9 with added Ca2+calmodulin to determine thein uence ofthe calmodulin on the inhibition of nNOS These experiments measured nNOS activity inthe presence of...
... outlined (in Section III) explaining why quote frequency data might be better entered in log, rather than in numerical, form, and we search for the best fitting transformation ofthe data using the ... trading close to the end of their day to avoid overnight inventory holdings There are few signs of any significant pattern in volatility between the days ofthe week, except for some indications of ... volatility ofthe market the spread increase can be attributed to the traders, fear of central bank interventions The busiest period ofthe day in terms ofthe number of quotations, measured by the half-hourly...
... IPOs that have preopening quotes The independent variables are: log of proceeds in millions ~SIZE!, number of quotes inthe preopening five-minute window ~PQUOTES!, the opening time of trading in ... stocks The lead underwriter starts the process by entering the first quote inthe five-minute preopening window These preopening quotes are not binding We find that this first quote is very informative ... quote data with the identity ofthe market maker to examine the quoting behavior ofthe lead underwriter during the preopening period; the behavior of other market makers; the importance of the...
... Part ofthe development ofthe Interpretative Quilt involved finding ways of bringing to this inquiry intuitive knowledge and ways of being in this world The water dream that gave birth to the ... patients’ beings moving in and out ofthe being ofthe world Paintings that are made while healing contain shadows of our histories They, too, fix in paint shadows of our memories, shadows of our thoughts, ... limitations that each rendering can provide This is true in inquiry as well as in art From my own experience of drawing or painting from life, I have become aware of how, during the process of painting,...
... shocks them into an acknowledgment of their alienation from the Divine As inthe previously related tales ofthe fate ofthe unrepentant ill sinner and ofthe justice who initiated the swearing of ... like them are shocking manifestations ofthe meaning of transubstantiation: the bread and wine literally "become" the body 20 The Grieff ofGodofGod It is small wonder thatinthe face of Lollard ... oaths, the stories often trade on fear ofthe Canseco quences of inflicting hurt on the Divine Inthe latter story, the people who adopt and persist in swearing and, by extension, the hearers of the...