... fragment Mothers with two different BSSL variants in their milk, e.g the most common 120-kDa variant together with one of lower mass, carried the deletion in one ofthe alleles, whereas the mother ... conÈ ®rming a different sequence ofthe tail The function ofthe tail has previously been discussed in the literature Deletion ofthe tail by in vitro mutagenesis ofthe human enzyme was shown to ... we believe that the resolution ofthe gel was insuf®cient to separate the two proposed transcripts The frequency ofvariation in exon 11 ofthe BSSL gene was determined by Southern blot experiments...
... sufficient genetic connection between herds Indeed, when genetic differences among herds are suspected, and, therefore, when part ofthegenetic variability may be confounded with the environmental ... combinations ofthe five dairy traits (ten analyses) The animal model used was the same for all combinations: where y is a vector of records n x rows (for n recorded goats), /3 is a vector of fixed ... Consequences of estimating the covariance components through bivariate analyses could not be evaluated but we verified the stability ofthe multiple variance estimates obtained for each trait, and also the...
... ambiguous phenotypic t trait The proof ofthe segregation of a major gene, if any, would then be the straightforward outcome ofthe inspection ofthe distribution of this quantitative variable considered ... ofthe muscle hypertrophy Furthermore, estimations ofthe gene effect and ofthe dominance deviation for this phenotypic criterion are then possible through the fitting ofthe appropriate mathematical ... to more than one gene (see the review , ENISSIER by M 1982) On the other hand, in most ofthegeneticanalysesof this condition so far published, the distribution ofthe animals into phenotypic...
... ferme / conforma- INTRODUCTION ofthe magnitude ofthe variance and covariance components is critical for thegenetic evaluation of animals and the development of sound breeding programs For ... Meyer, 1992) The present estimates for maternal genetic effects in French Limousin breed were in the lower tail ofthe gain from birth = ranges The estimates ofthe ratio between the maternal ... weights of beef calves depend primarily upon the joint expression of preweaning growth potential of calves and maternal traits (primarily the milk production) of their dams The relative importance of...
... selection for most traits, the criterion of selection is not the only characteristic altered during genetic manipulation The ability of an organism to maintain a balance of soft tissue mass (muscles, ... body size has not been reported extensively in the scientific literature, perhaps because reduced body size is not economically advantageous in agricultural animals The testing ofgenetic theory ... they were heavier than the low-weights Hatch weight was a function of egg weight, which was lower for line B Slowing ofthe growth rate for line L chicks in the juvenile stage resulted from the...
... prior to analyses Analysis ofthe populations in this study allowed examination ofthe influence of a major gene on age at sexual maturity Comparisons of combined frequency distributions ofthe backcrosses ... in these Bantam pullets Conversely, the significant difference between combined frequency distribution ofthe backcrosses to the LL with the combined frequency = = frequency distribution ofthe ... DISCUSSION Genetic control of age at sexual maturity Shapes ofthe frequency distributions of age at first egg in generation prompted to produce generation for further study The overdominance of F...
... read may span the breakpoint ofthe CNV SR analysis has the advantage of being able to pinpoint the location ofthe breakpoints Assembly-based AS methods, on the other hand, not align the reads to ... 54 LIST OF TABLES Table 2.1: Definition ofthe different classes ofgenetic variations, partly adapted from Figure of Scherer et al., 2007 *only selected types ofvariation are defined ... speculations that the costs associated with down-handling, storing and analysis ofthe data could be more than the production ofthe data There is still a need for the development of new statistical/bioinformatics...
... analysed in the form of a series of 12 monthly totals, these being the numbers of persons presented with the disease of interest in a given month ofthe year Often the data of onset have been gathered ... ∑ wg = ∑ N g The distance of COG from the geometric centre ofthe g g circle is 12 dE = S + C (2.4) The direction of COG with respect to the geometric centre ofthe circle, is then determined ... description, under the term periodic regression, ofthe use of sinusoids in the analysis ofthe biological cycles The simplest sine curve is a generalization of Roger’s method ofthe form Y = α +...
... the electronic band offset for the InAs/GaAs ring structures, parameter a control the slope and range ofthe potential change at the boundaries ofthe ring Using the potential (2) we define the ... quantum ring, the standard approach is to calculate the total electronic energy ofthe ring in the presence ofthe external magnetic field B The magnetization and magnetic susceptibility ofthe ring ... present the magnetic susceptibility ofthe ensemble ofthe rings Obviously, the peak ofthe magnetic susceptibility demonstrates the temperature stable behavior, which has to be attributed to size...
... T)11 and T+2 Therefore, the measured contribution of these forms to the integrated intensity of these two bases was used in the calculation ofthe contribution of individual bases to the integrated ... charge on the phosphate group, thereby diminishing the electrostatic barrier to diffusion of MnO4 to the reactive double bond ofthe thymine moiety Mg2+ effect on the kinetics of oxidation ofthe RPoPa ... 0.05 0.25 0.05 1.7 ofthe t strand The patterns of thymine reactivity in the presence and absence of Mg2+ were generally similar In the absence of Mg2+, the reactivity of all the thymines was merely...
... variance between the lines, the variances ofthe phenotypic and additive variances ofthe lines will be the same and, therefore: where fl j CV(V and h are the coefficient ofvariationofthe phenotypic ... number of bristles on the 5th and the 6th sternites remains constant over lines, the variance ofthe phenotypic and thegenetic covariances between these traits will be the same and, therefore, their ... 1984) Part ofthe theory mentioned above has not yet been tested, specifically that concerned with the prediction ofthe changes ofthevariation among replicates in the within-replicate genetic...
... genotype to corresponding variations in transcript levels However, thesize constraints of these species necessitates the use of sample pools composed of hundreds to millions of discrete organisms, ... point in time The inter-strain measurements reflect the additional contribution of heterogeneity at the level ofthe genome deposited research To assess the effects of pooling on the ability to ... supplemental Figure 2) The significance of these F-values was determined through estimating the pFDR, which is the proportion of falsely rejected hypotheses among the rejected hypotheses for pre-selected...
... et al, in their study, have evaluated the link between the timing of conception with risk of preeclampsia [13] They found the highest risk of preeclampsia in conceptions occurring in the summer ... period Graph showing the variationthethe monthly average morning Graph showing thevariation in the monthly average morning barometric pressure during the study period Page of (page number not ... than the rest ofthe year (32.3°C) Whether such changes in plasma volume occur in these climatic conditions is not known The 10 11 12 13 14 Figure during showing period Graph the studythe variation...
... and function ofthe hormonal system We first cloned the genes ofthe CYP11B family ofthe guinea pig The 11bhydroxylase ofthe guinea pig showed higher substrate specificity than the aldosterone ... screening ofthe cDNA library did not result in the identification of any cDNA other than CYP11B1 (data not shown) Thus, we devised another strategy for the identification of additional genes ofthe ... than CYP11B2 [29] Moreover, the activity ofthe guinea pig CYP11B2 compared to CYP11B1 could be correlated to thesizeofthe C17 substituent ofthe substrate Thus, the differences were most pronounced...
... particles within the first and slowly increasing further beyond 400–500 nm, the limit of detection by DLS, as a function of time The width of distribution of Rh was in the range of % 50 nm in these samples ... MutS-MutL-Heteroduplex (121 bp) Fig Analysesofthe Rh distribution of MutS as a function of its interaction with MutL (A) Analysesofthe Rh distribution of MutS as a function of its interaction with MutL ... added either at the start or at the 20-min time-point ofthe reaction Interestingly, addition of salt at the start ofthe reaction essentially abrogated mismatch induced discrimination of MutS...
... addressed, the global context ofthe domain analyses allows us to draw a more general picture ofthe involvement of this gene in nuclear processes Nonetheless, the data presented here build a hypothesis ... from the other branches, which was indeed predicted The other main group, obtained 97% ofthe time in 20 740 explored trees, contained the DIDO PHD sequences clustered with the PHF and the CGBP ... among the sequences and always follows the PHD domain Using PSI-BLAST, the dPHD of DIDO1 hits CGBP_ MOUSE at the second iteration, with an e-value of 2e-06 (inclusion threshold of 0.03) In SPP1, the...
... within the vicinity ofthe HRA, but were often noted using the beach and the spit There was some brood use at South Tenmile alongthe foredune to north ofthe boundary ofthe closed area There ... or alongthe foredune was from about half the distance to the HRA to the north end ofthe HRA Broods from the HRA moved north or south alongthe foredune as well as stayed on the HRA The southern ... because the number of fledglings produced in a given year is a function ofthe number of males in the population The number of nest attempts is a function ofthe number of available males and the...
... was found just south ofthe ropes at the very south end ofthe HRA near the mouth of Twomile Creek/New River The southern end ofthe HRA had no plover use due to the lack of habitat At New River ... on the HRA for the second year in a row, which continues to degrade due to the lack of management The northern half ofthe HRA from New Lake breach north had the best habitat, and most ofthe ... south of China Creek overwash Five nests were found alongthe foredune further south ofthe old camp trail and north ofthe HRA Ten nests were found on the HRA, and one nest was found just south of...
... eliminate the possibility ofthe functional roles ofthe )643T>C and )1219G>A SNPs as part ofthe extended APOH promoter transcriptional machinery To further substantiate the functional relevance ofthe ... conjunction with the luciferase gene in pGL3basic vector The nucleotides are numbered from the translation start site The effect ofthe wild-type and mutants was measured as the mean ofthe firefly luciferase ... purpose, we tested 12 ofthe 14 sequence variants located within the 1418 bp ofthe 5¢ flanking region of APOH for allele-specific regulatory effects on the expression ofthe dual luciferase reporter...
... that these residues stabilize the distortion ofthe NAG3 residue In these interactions, we particularly focused on the Trp664 residue, which is located at the bottom ofthe active site cleft The ... Stereo figures ofthe model ofthe bound substrate in the AD2 E526A mutant (A) and D524A mutant (B) The structures of bound sugars and the side-chains of three acidic residues in the conserved ... distortion and twisting ofthe substrate, so that the glycosidic oxygen faces towards the bottom ofthe deep cleft A Asp636 NAG1 Enzyme–substrate interactions The crystal structures ofthe AD2 E526A and...