quality by design and risk assessment for radiopharmaceutical manufacturing and clinical imaging
computational toxicology - risk assessment for pharmaceutical and environmental chemicals - s. ekins (wiley, 2007)
... Agonists and antagonists for adrenocortical hormones have been described Oral contraceptives are risk factors for increased blood clotting and stroke Estrogens are risk factors for breast and uterine ... ASSESSMENT: ENVIRONMENTAL The Toxicity and Risk of Chemical Mixtures 599 601 John C Lipscomb, Jason C Lambert, and Moiz Mumtaz 22 Environmental and Ecological Toxicology: Computational Risk Assessment ... Institute for Bioinformatics, GSF–National Research Centre for Environment and Health, Ingolstädter Landstraße 1, D-85764 Neuherberg, Germany (itetko@vcclab.org) Weida Tong, Center for Toxicoinformatics,...
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landslide hazard and risk assessment for road network using rs and gis a case study of xin man district, vietnam
... Vulnerability Vulnerability Assessment Land Vulnerability Funtional Vulnerability Risk Assessment Figure 2.1: Criteria for risk assessment (Disaster Preparedness and Mitigation-2002) 2.2 Landslide Hazard ... 1987 and 2000, which are use for the extraction of land surface temperature and landuse information 1:25000 scale standard topographic map has been digitized and the obtained contours were used for ... Cultivated land Brush and thin forest Bareland Dense forest Landcover classes Figure 3.9: Landcover chart Map 3.8: Landcover map in Xin Man 31 Map 3.9: Road system in Xin Man 32 CHAPTER METHODOLOGY AND...
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Gait speed and risk assessment for falls among men aged 80 years and older a prospective cohort study in taiwan
... step in the risk assessment, and a number of tests were recommended, such as Get up and Go test, Timed Up and Go test, the Berg Balance Scale, and the Performance-Oriented Mobility Assessment ... co-morbidities by using Charlson Comorbidity Index [17], and body mass index (BMI) were obtained for each study subject 2.2.2 Comprehensive Geriatric Assessment (CGA) The research nurses performed CGA for ... simple and efficient approach to stratify risk of falls for people aged 80 years and older Table Independent risk factors for falls among men aged 80 years and older during 12-month follow-up Independent...
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Radiological risk assessment for Al-Twuaitha nuclear site in Iraq
... (2000) While for Usum the level exceed the permitted level by (75) times and for 60Co by (5000) times and for 137Cs by (3850) times and for 90Sr (97) times The skewness coefficient for the distribution ... confidence interval The risk assessment and sensitivity analysis for hotspot 1, 2, 3, and total risk are calculated for beta function at the mean of 1.34, 488, 20.1, 0.123 and 469 mSv/y respectively ... that 60Co and 137Cs were the most influence parameters Conclusion The risk assessment and sensitivity analysis charts shows significant risk for the selected hotspots zones The total risk is dominated...
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Ecological Risk Assessment for Contaminated Sites - Chapter 2 docx
... procedure for risk assessments performed for the Oak Ridge Reservation is contained in Risk Assessment Program (1997) 2.7.3 REFERENCE SITES AND REFERENCE INFORMATION When performing a risk assessment, ... be suitable for risk assessment Detection limits for analyses of reference media may be too high or the quality assurance and quality control may not be up to the standards required by regulators ... baseline risk assessment and explicitly describe the sampling, analysis, and data review tasks? (Source: Office of Emergency and Remedial Response, 1992c.) will be used in the risk assessment Therefore,...
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Ecological Risk Assessment for Contaminated Sites - Chapter 3 potx
... useful for screening assessments, but the dissolved form is appropriate for definitive risk assessments of aquatic biota for two reasons First, the form in the exposure assessment should match the form ... total metal analyses were performed in any case for the assessment of risks from human and wildlife drinking water Speciation should be considered for both inorganic and organic chemicals that ... useful for scoping and screening assessments but are unlikely to be acceptable for definitive assessments Two different expressions of sediment contamination are commonly used in ecological risk assessments:...
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Ecological Risk Assessment for Contaminated Sites - Chapter 4 potx
... Variable Perciformes Tetraodontiformes Perciformes Gasterosteiformes Atheriniformes Cypriniformes Tetraodontiformes Perciformes Gasterosteiformes Tetraodontiformes Perciformes Tetraodontiformes n ... Siluriformes Anguiliformes Anguiliformes Anguiliformes Anguiliformes Atheriniformes Atheriniformes Atheriniformes Atheriniformes Gasterosteiformes Gasterosteiformes Perciformes Mean Weighted ... Salmoniformes Salmoniformes Salmoniformes Cypriniformes Cypriniformes Taxonomic Extrapolation: Orders within Classes Cypriniformes 225 Siluriformes 203 Perciformes 443 Siluriformes 111 Perciformes...
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Ecological Risk Assessment for Contaminated Sites - Chapter 6 ppt
... the risk manager in making a remedial decision and to promote understanding by stakeholders and the public The risk characterization should have determined, for each assessment endpoint, which risks ... Reasonable, and Consistent Risk Characterizations For clarity: • Be brief; avoid jargon • Make language and organization understandable to risk managers and the informed layperson • Fully discuss and ... proposed for assessment of risks from contaminated water or sediments by Salazar and Salazar (1998) Exposure is estimated by analysis of the ambient medium, dose by analysis of tissue chemistry, and...
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Ecological Risk Assessment for Contaminated Sites - Chapter 7 doc
... weighting of the risks from contaminants and risks from remediation In typical communities, risks from contaminants are unfamiliar, involuntary risks, and risks from remediation are familiar and voluntary ... remediation required; RLU = remediation by land-use controls; B = balancing of risks and nonrisk factors by the risk managers is required Source: Suter II, G W et al., Risk Anal., 15, 221, 1995 With permission ... 9.4) For example, if both human health and ecological risks are de minimis, remediation is not necessary if the methods and results of the risk assessment are acceptable to the risk managers and...
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Ecological Risk Assessment for Contaminated Sites - Chapter 8 doc
... different role in ecological risk assessments than they in human health risk assessments For human health risk assessments, remediation depends on the land-use scenario because land use determines human ... exposure depends on land use, and risk- based remediation should depend on land use In ecological risk assessments, three issues must be considered with respect to post-remedial land use What habitat ... piscivores may not forage The PRG for a particular chemical cannot be assumed to protect piscivorous wildlife if information on the toxicity is not available As in the risk assessment for aquatic organisms,...
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Ecological Risk Assessment for Contaminated Sites - Chapter 10 pot
... intensive, and expensive 10.2.3 ASSESSMENT PHASE The assessment phase is equivalent to the analyses of exposure and effects and the risk characterization in a conventional ecological risk assessment ... as tiered assessments with increasingly rigorous analysis NRDAs might benefit from the logic of the ecological risk framework and from the ability to adopt risk assessments performed for the remedial ... the preassessment screen be carried out rapidly with existing information, and that any sampling follow the screening phase However, sampling may be performed before completion of the preassessment...
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Ecological Risk Assessment for Contaminated Sites - Appendix (end) pdf
... and ecological risk assessment Risk Anal 14:477–481 Burmaster, D E and D A Hull 1997 Using lognormal distributions and lognormal probability plots in probabilistic risk assessments Hum Ecol Risk ... macroinvertebrates for exposure evaluation These methods include grab -and- core samplers for standing © 2000 by CRC Press LLC waters and kick sampling, Surber samplers for running water, and artificial ... Carlo Hum Ecol Risk Assess 2:627–1037 Callahan, C A and B D Steele 1998 Ecological risk assessment guidance for Superfund sites In A de Peyster and K E Day (Eds.), Ecological Risk Assessment: A...
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Báo cáo y học: " Changes in health-related quality of life and clinical implications in Chinese patients with chronic cough" pot
... health-related quality of life (HRQOL) provoked by cough can be accurately analyzed, which is useful for assessment of cough severity and therapeutic efficacy, and can help to guide clinical practice and ... psychological and social domains, and each item represents an adverse event caused by cough [6] A 7-point Likert scale is used for scoring the answer Like SF-36, LCQ is also designed for selfadministration ... identified and treated by our established protocol [15] Just before the specific treatment was initiated, SF-36 and LCQ were filled out by the patients under the guidance of doctors and capsaicin...
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Water Quality Guidelines, Standards and Health: Assessment of risk and risk management for water-related infectious disease docx
... Water Quality Guidelines, Standards and Health: Assessment of risk and risk management for water-related infectious disease This page intentionally left blank Water Quality Guidelines, Standards and ... exposure assessment is an important input to both the assessment of risk and to risk management Exposure assessment is a formal component of the risk assessment process (Chapter 8) Exposure assessment ... improve water quality by source protection, by affordable treatment and disinfection and by household water treatment and storage 2.3 SAFE USE OF WASTEWATER AND EXCRETA IN AGRICULTURE AND AQUACULTURE...
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Ecological Assessment of Water Quality by Three-species Acute Toxicity Test and GC/MS Analysis - A Case Study of Agricultural Drains
... daphnia immobilization On the other hand, for a frequency of 100%, the effect ratio was observed as 0% for algae and 11% for fish, while it was 45% for daphnia For 43 water samples on 28 sites (38% ... effect ratio for a frequency of 10% or less was observed to be 86% for algae growth inhibition and 62% for fish mortality, while for a frequency of 20% or less, it was observed to be 33% for daphnia ... compounds had been shown each goal value (GV) for water quality control in the Water Supply Law of Japan, and had been prepared a mixture standard solution for simultaneous analysis commercially (Wako...
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báo cáo hóa học: " Co-morbidity and visual acuity are risk factors for health-related quality of life decline: five-month follow-up EQ-5D data of visually impaired older patients" ppt
... and three general hospitals in the Netherlands between July 2000 and January 2003 The eligibility requirements for inclusion in the non-randomized study were referral to low-vision services for ... and revised the manu- Page of (page number not for citation purposes) Health and Quality of Life Outcomes 2009, 7:18 script for important intellectual content; GHMBVR conceived of the study and ... provided by: 'ZonMw – Inzicht' (The Netherlands Organisation for Health Research and Development – Insight Society, The Hague, Grant no 943-03-017), 'Stichting Oogfonds Nederland', Utrecht, and 'Stichting...
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Báo cáo hóa học: " Development of a parent version of the Manchester-Minneapolis quality of life survey for use by parents and carers of UK children: MMQL-UK (PF)" potx
... different forms, one for children aged 8–11 (Child form, MMQL-CF), one for 12–18 year olds (Youth Form, MMQL-YF) and one for young people aged 19–25 years All the original child MMQL forms measured ... to discuss the project further and arrange for data collection Written information for parents, parental consent forms and parent questionnaires were supplied for each child to take home Parents ... body image and outlook on life Intimate relations was an additional component in the questionnaires for 12–18 and 19–25 year olds No parent form is available for the original MMQL forms The anglicised...
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Health and Quality of Life Outcomes BioMed Central Review Open Access Needs Assessment for cancer potx
... levels of performance on each need; measuring the importance of needs and employing needs assessment data in design; and improvement and evaluation efforts We will first examine how needs assessment ... quality of life This understanding is important for designing and conducting needs assessments If a needs assessment prioritizes which needs should be addressed, and if that assessment is done without ... where and how to prioritize and focus improvement efforts.- At the same time, needs assessment should give patients and families a chance to identify and express the issues they want recognized and...
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báo cáo khoa học: "The efficacy of computer reminders on external quality assessment for point-of-care testing in Danish general practice: rationale and methodology for two randomized trials" pot
... 23 July 2011 Published: 23 July 2011 References Quality standards and quality assessment system for frequently performed clinical biochemistry and clinical microbiological tests in general practice ... point of care testing and is a prerequisite for receiving fees for this service Apply number 010158-6006 for ordering external quality assessment analysis in WebQuality system For questions, please ... practices and corresponding GPs Page of and control arms, randomization within each RCT is done separately for group practices and solo practices respectively This randomization was conducted by the...
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báo cáo khoa học: " NorthStar, a support tool for the design and evaluation of quality improvement interventions in healthcare" ppt
... evaluation suggest that NorthStar will form a useful reference and educational tool for QI research in general, and for developing a protocol for a cluster randomised trial, in particular Potential ... electronic document formats and can, therefore, include not only textual information but graphics, documents created by other programs, sound, video, as well as links to websites and other programs ... (Clinical Practice Guidelines) It also discusses the why, what and how of measuring baseline performance defined as the measurement of actual clinical practice and its comparison to desired clinical...
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