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prognostication and prediction in anatomic pathology carcinoma of the breast as an illustrative model

Pathobiological predictors of behavior in invasive lobular carcinoma of the breast

Pathobiological predictors of behavior in invasive lobular carcinoma of the breast

Thạc sĩ - Cao học

... Medullary carcinoma Invasive papillary carcinoma Invasive cribriform carcinoma Metaplastic carcinomas • Pure epithelial metaplastic carcinomas →Squamous cell carcinomas →Adenocarcinoma with spindle ... classification of breast cancer WHO classification of breast cancer (2003) Epithelial tumours Invasive ductal carcinomas of no special type • Mixed type carcinoma • Pleomorphic carcinomaCarcinoma ... 6.2% of breast cancer classified as ILC (Pestalozzi et al 2008) In Singapore, the incidence of ILC was on the low end of the range From 2003-2007, ILC comprised 3.9% of all breast cancers (Singapore...
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Báo cáo khoa học:

Báo cáo khoa học: "Genomic alterations of primary tumor and blood in invasive ductal carcinoma of breast" pdf

Báo cáo khoa học

... types of human cancers including breast cancer [35] Other candidate genes have been described as frequently imbalanced in the genomes of the breast cancer cells (Figure 3) Gain on 8q24.3 and 20q13.33 ... 20q13.33 was identified in more than 50% of the samples Gain on 17q11.2 was seen in 19 of the primary tumors (63%) and in 17 of the blood samples (57%) The region included the myosin XVIII A ... associated with metastasis and relapse of breast cancer, and is overexpressed in lymph node positive breast cancer [38] Gain on 22q13.33 was over represented in 15 primary tumor and 15 blood samples...
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The expression of CD44s in squamous cell carcinoma of the oral tongue and association with clinicopathological factors and survival outcomes

The expression of CD44s in squamous cell carcinoma of the oral tongue and association with clinicopathological factors and survival outcomes

Cao đẳng - Đại học

... concentration of glycosaminoglycan-associating proteins, increasing the capacity of these ligands to interact with their receptors, thereby lowing the threshold for signal transduction The binding of such ... in the cell membrane and influences CD44-mediated signal transduction The cytoplasmic partner molecules of CD44 are the cytoskeleton proteins ankyrin and ezrin, radixin and moesin (ERM proteins) ... of such ligands, including osteopontin and 23 vascular endothelial growth factor, are of interest in the metastatic process.53-55 Apart from maintaining the niche matrix surrounding cancer stem...
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The graphs below show the numbers of male and female workers in 1975 and 1995 in several employment sectors of the republic of Freedonia

The graphs below show the numbers of male and female workers in 1975 and 1995 in several employment sectors of the republic of Freedonia

Kỹ năng viết tiếng Anh

... made gains in both the finance/banking industries and in the defence-related public sector Whereas some 125 000 women worked in finance and banking institutions in 1975, the number increased to ... model answer: The two decades between 1975 and 1995 brought significant changes in the representation of women in Freedonia's work force, according to the graphs In 1975, for example, ... men and 250 000 women worked in the communications sector Twenty years later, though the number of men remained unchanged, the number of women rose to 550 000 A similar situation was seen in the...
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Báo cáo khoa học:

Báo cáo khoa học: " Preoperative external beam radiotherapy and reduced dose brachytherapy for carcinoma of the cervix: survival and pathological response" potx

Báo cáo khoa học

... insertions of Gy The median dose of brachytherapy to point A was 12 Gy (range 6–15 Gy) and the mean point A dose was 11.8 Gy According to the beliefs of the assistant physician, 11 patients with ... Chemotherapy was not administered to any of them Median age was 46 years (range 22–72) Squamous cell carcinoma was the histological type in 56 patients (84%); adenocarcinoma in (13%); and patients ... distant control In fact, the standard approach for advanced cervical cancer has been changed after randomized trials and a meta-analysis demonstrate significant benefit of concomitant chemoradiotherapy...
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Báo cáo y học:

Báo cáo y học: "Trends towards an improved disease state in rheumatoid arthritis over time: influence of new therapies and changes in management approach: analysis of the EMECAR cohort" ppt

Báo cáo khoa học

... mass index and the DAS28-3, the HAQ score and the Larsen score at baseline Bivariate analysis was performed with all factors and covariates, and then backward stepwise selection was applied in ... used in four patients during 2000 and used in three patients in 2004 Effect of time and treatment on disease The median (interquartile range) of the DAS28-3 was 4.0 (3.0 to 5.1) in 2000, and this ... analysis and helped to draft the manuscript IG-A participated in the design of the study and also in collection of the data at the Hospital Universitario de la Princesa, was involved in the interpretation...
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báo cáo khoa học:

báo cáo khoa học: "Adenoid cystic carcinoma intermingled with ductal carcinoma of the breast: a case report and review of the literature" docx

Báo cáo khoa học

... prognosis, as the incidence of lymph node metastasis is lower and distant metastases uncommon [1] Even rarer are the cases of ACC intermingled with other types of breast cancer within a single lesion ... ACC of the breast is a rare histopathologic type of slow progression and represents only 0.1% of breast cancer cases In sharp contrast to the extra-mammary counterpart, ACC of the breast has an ... the histological examination of the specimen and contributed to the writing of the manuscript All authors read and approved the final manuscript Competing interests The authors declare that they...
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báo cáo khoa học:

báo cáo khoa học: "Surgical treatment of intracystic carcinoma of the breast" doc

Báo cáo khoa học

... also included one male patient Since breast cancer in men accounts for only about 1% of all breast cancers, the incidence of intracystic carcinoma of the breast in men appears to be higherand and ... because breast cancer in which a lesion existed within the cystic wall was investigated as intracystic carcinoma of the breast Patients with intracystic carcinoma of the breast tend to be older than ... 1.9% of all breast cancers [2,3] According to the general rules for clinical and pathological recording of breast cancer, a lesion localized in a cyst is defined as noninvasive intracystic carcinoma...
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Báo cáo khoa học:

Báo cáo khoa học: "The clinical behavior of mixed ductal/lobular carcinoma of the breast: a clinicopathologic analysis" pptx

Báo cáo khoa học

... fibrocystic changes in the contralateral breast Thus, there was no case of contralateral invasive breast cancer The 12 cases of invasive ductal breast carcinoma also had no contralateral breast cancer ... ductal/lobular breast carcinoma who had MRI of the breast, and out of 12 patients (16.66%) had suspicious contralateral lesions On review of the pathology, one case had carcinoma in- situ and other case ... with the group of 10,061 cases, mostly of the invasive ductal type (91% of cases), observed during the same period The focus of the study was the comparison of ductal carcinomas to lobular carcinomas...
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Báo cáo khoa học:

Báo cáo khoa học: "Glycogen-rich clear cell carcinoma of the breast" pps

Báo cáo khoa học

... Clear-cell carcinoma of the breast, resembling clear-cell carClear-cell carcinoma of the breast, resembling clear-cell carcinoma of the kidney The lobular arrangement and the fine vascular network ... drafting and revision of the manuscript, DM: Helped in preparation and revision of the manuscript, TP: revision of the manuscript and preparation of histology and immunoassays, EK: Surgery and follow-up ... leaving vacuolated cytoplasm Extraction of the cytoplasmic components also occurs in lipid-rich carcinoma, signetring cell carcinoma and in some secretory variants of ductal or lobular carcinomas,...
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Báo cáo khoa học:

Báo cáo khoa học: "A case of matrix-producing carcinoma of the breast" pps

Báo cáo khoa học

... triple-negative breast cancer [14,15], and this is important in terms of elucidating the etiology of the metaplastic change Ninomiya et al., reported that one of their two cases of MPC of the breast was the ... that the incidence of MPC of the breast was 0.05% in Japan [4] Our search of the main Japanese medical journals found a total of 27 cases of MPC of the breast reported in Japan to date, including ... histogenesis of MPC We report our findings for a Japanese woman with MPC of the breast and discuss them together with the other 26 cases of MPC of the breast that have been reported in Japan to date Case...
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Báo cáo khoa học:

Báo cáo khoa học: " Squamous cell carcinoma of the breast: a case report" docx

Báo cáo khoa học

... adenocarcinoma of the breast and from metastasis of squamous cell carcinoma of an origin somewhere else The etiology and pathogenesis of squamous cell carcinoma of the breast is still unclear It has ... cell carcinoma of the breast Clin Breast Cancer 2005, 3:270-272 Zoltan TB, Konick L, Coleman RJ: Pure squamous cell carcinoma of the breast in a patient with previous adenocarcinoma of the breast: ... of the of the right breast of the patient in two directions Mammogram of the of the right breast of the patient in two directions Clearly visible the mass, located behind the nipple Page of (page...
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Báo cáo y học:

Báo cáo y học: "nvasive lobular carcinoma of the breast presenting as retroperitoneal fibrosis: a case report" ppsx

Báo cáo khoa học

... comparison of the metastatic pattern of infiltrating lobular carcinoma and infiltrating duct carcinoma of the breast Br J Cancer 1984, 50:23-30 Lamovec J, Bracko M: Metastatic pattern of infiltrating ... negative Based on these findings, a diagnosis of metastatic invasive lobular carcinoma of breast origin was made Discussion Cases of ILC metastasizing to the peritoneal cavity and retroperitoneum ... is the interobserver and sometimes intra-observer variability in diagnosing metastatic lobular breast carcinoma at the time of frozen section In a series of invasive lobular versus ductal carcinoma...
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Báo cáo khoa hoc:

Báo cáo khoa hoc:" Posterior dislocation of the elbow as an unusual presentation after a total hip replacement: a case report" pdf

Báo cáo khoa học

... dynamic structures -the muscles crossing the elbow joint [6] Recent studies continue to develop our understanding of the role and importance of the primary and secondary stabilizers of the elbow Disruption ... the elbow joint and minor ectopic calcification in the lateral joint region of the elbow (Figure and 4) On further questioning the patient and her parents, they recollected that the patient had ... of the LCLC and the importance of each component and the surrounding soft tissues and the mechanism of poster lateral rotatory instability (PLRI) continue to be investigated and debated Additional...
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Báo cáo y học:

Báo cáo y học: "Extramedullary plasmacytoma of the pancreas as an uncommon cause of obstructive jaundice: a case report" ppsx

Báo cáo khoa học

... bosselated mass, not related to the ulcer, was noted occupying the head and neck of the pancreas There was no evidence of local invasion A biopsy of the pancreatic mass was taken The patient’s ... assisted in the revision of the manuscript JP was a major contributor in the writing of the manuscript and provided guidance through the process All authors read and approved the final manuscript ... diagnosis of multiple myeloma was made immediately following the diagnosis of the plasmacytoma of the pancreas The typical presentation of extramedullary plasmacytomas of the pancreas includes...
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Báo cáo y học:

Báo cáo y học: " Hydatid cyst disease of the lung as an unusual cause of massive hemoptysis: a case report" ppsx

Báo cáo khoa học

... examination were normal (No other pathology was obtained.) In laboratory findings, values for C-reactive protein of 1.99 mg/dl, alanine transaminase of 26 U/litre, aspartate transferase of 14 ... was involved in the management of the patient as well as writing the case reports ST took the photographs AG and MME were involved in the correction of the manuscript as well as general supervision ... segment of the upper lobe of the right lung and multiple lesions neighboring the former, some of which were cystic and the others solid (the largest was cm in diameter) In addition, a cm lesion was...
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Báo cáo y học:

Báo cáo y học: "Multivariate explanatory model for sporadic carcinoma of the colon in Dukes’ stages I and IIa"

Y khoa - Dược

... constructing a statistical model with the controls gathered in primary care and the cases, and later, by constructing another model with the controls gathered in the hospitals and with the same cases ... observed in cases of stomach carcinoma, carcinoma of the gall bladder and/ or biliary tract, and hepatomas Up until now it has not been considered as a valid instrument of SCRC screening because of ... ratio (OR) in a structural manner in the designs of cases and controls [23] As a final step in the validity study, a “bootstrap” analysis was applied to the complete sample of cases and controls...
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Báo cáo khoa học:

Báo cáo khoa học: "Age Prediction in Blogs: A Study of Style, Content, and Online Behavior in Pre- and Post-Social Media Generations" ppt

Báo cáo khoa học

... pre-processed the data to add Part-ofSpeech tags (POS) and dependencies (de Marneffe et al., 2006) between words using the Stanford Parser (Klein and Manning, 2003a; Klein and Manning, 2003b) The POS and ... excludes the emoticons and acronyms counted in the other features, increased as well, but not as significantly The length of sentences decreased as bloggers got younger and the number of links/images ... Facebook and MySpace In the future we plan on using age and other metadata to improve results in larger tasks such as identifying opinion, persuasion and power by targeting our approach in those tasks...
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báo cáo hóa học:

báo cáo hóa học:" Regulation of microRNA biosynthesis and expression in 2102Ep embryonal carcinoma stem cells is mirrored in ovarian serous adenocarcinoma patients" pdf

Hóa học - Dầu khí

... was carried out using the TaqMan® microRNA assay early-access panel (AB) as per manufacturer's instructions This panel included assays for each of the 330 human miRNAs known at the start of the ... that the mechanisms facilitating tumourigenesis without differentiation may represent an avenue for targeting Ovarian cancer is the 8th leading cause of cancer in women in the US and the leading ... The expression of miRNAs was assessed both globally, via the expression of miRNA biosynthesis genes Drosha, Dicer and eIF6, and individually, via quantitative miRNA qPCR analysis of a panel of...
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báo cáo hóa học:

báo cáo hóa học:" Augmented inhibition of angiogenesis by combination of HER2 antibody chA21 and trastuzumab in human ovarian carcinoma xenograft" pptx

Hóa học - Dầu khí

... HER2-overexpressing ovarian carcinoma Our data showed that chA21 and trastuzumab can inhibit tumor growth and angiogenesis in SKOV-3 xenograft model and the combination of trastuzumab with chA21 results in an ... result in poor clinical outcome Trastuzumab as the first therapeutic anti-HER2 monoclonal antibody has been used in clinical treatment of HER2-overexpressing metastatic breast and gastric cancers ... monotherapy could inhibit human ovarian carcinoma cell line SKOV-3 growth in vitro and in vivo [16] In this study, we further investigated if more effective inhibition of angiogenesis is one of the...
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