process analytical technology in solid dosage development and manufacturing
Development of high speed video imaging as a process analytical technology (PAT) tool
Ngày tải lên :
11/09/2015, 10:00
... between the chemical engineering and pharmaceutical industries, the pharmaceutical industry is largely lagging behind in terms of process understanding and selftuning process control (Basu, 2009) ... Condensation and compression may occur in this stage In the melting zone, the screw is designed to exert extensive shearing and mixing on the solids, causing a rise in solids temperature The heating jacket ... However, lacking fundamental understanding of the manufacturing processes, the manufacturing process parameters have to be tightly controlled to ensure consistency in the final product quality In the...
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process analytical technology
Ngày tải lên :
02/04/2014, 16:24
... evolution from off-line and at-line analysis, to intermittent on-line analysis, continuous on-line analysis, then in- line analysis, and non-invasive analysis The terminology defining the different ... Knoxville and is strong in Raman spectroscopy and mass spectrometry, and in applying analytical technology to the chemical engineering of controlling the process MCEC has members from the chemistry and ... feedback The elimination of manual sample handling with the inherent gain in safety and, to some extent, the elimination of operator error (and being able to maintain sample integrity) The general...
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Báo cáo y học: "Cartilage oligomeric matrix protein is involved in human limb development and in the pathogenesis of osteoarthriti" pptx
Ngày tải lên :
09/08/2014, 07:20
... again, and finally dissolved in PBS containing 0.4% SDS All experiments were carried out under reducing and denaturing conditions Protein separation was performed applying SDS-PAGE and using ... Bars, 70 µm in (a), (b), and inset (c) and 40 µm in (c) and insets (a) and (b) ure 2, lane 2) The 105 kDa band for a monomer was seen in both extracts, whereas a second band was found only in the ... Bars, 0.4 µm in (a) and (b) and 0.2 µm in (c) and inset joint cartilage tissues in the pericellular, territorial, and interterritorial matrix compartments This was seen in the superficial and middle...
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Genes involved in colon cancer development and progression
Ngày tải lên :
07/10/2015, 10:02
... plasmin upon activation Plasmin will in turn assist in the degradation of extracellular matrix (ECM) and activation of pro-MMPs in the extracellular space Signalling processes involving β1 integrin ... category Integrins act as a relay machine by transmitting extracellular signals into activation of intracellular signaling processes Integrins are able to bind to many ECM molecules, causing the ... examples of the scoring performed on HDACs and staining Grade is defined as negative staining of the nucleus, while grades to represent increasing intensity of nuclear staining The upper panel...
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Design and development of major balance of plant components in solid oxide fuel cell system
Ngày tải lên :
05/09/2013, 16:10
... reforming or partialoxidation reforming In the INER SOFC system, the reforming process is performed using a combination of these two methods by feeding both steam and an oxidant (air) into a ... Energy Research He holds a PhD in environmental engineering, M.S and B.S in chemical engineering His research interests include biomass reforming, hydrogen generation and low level radwaste treatment ... University in Taiwan, 2006 He was a junior researcher at the Institute of Nuclear Energy Research Now he is working at the Refining and Manufacturing Research Institute, CPC Corporation, Taiwan and...
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Tài liệu Báo cáo khoa học: Inorganic pyrophosphatase in the roundworm Ascaris and its role in the development and molting process of the larval stage parasites doc
Ngày tải lên :
20/02/2014, 11:20
... concerning the kinetics and properties of the enzyme More strikingly, we show a novel role of the PPase enzyme in the development and molting process of A suum larvae in vitro constructed in UniZap ... (Michaelis constant) and Vmax (maximum velocity) values were determined by incubating the diluted recombinant proteins in the standard reaction mixture in the presence of increasing concentrations ... were removed and minced with a surgical knife The minced tissue was wrapped in cotton gauze and suspended in NaCl/Pi containing 100 lgÆmL)1 penicillin/ streptomycin at 37 °C for h After incubation...
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Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 2 docx
Ngày tải lên :
21/06/2014, 10:20
... A-series (A1~A5) and C1 The excitation and detection wavelengths of the luminescence were at 500 and 1120 nm, respectively The luminescent intensity nonlinearly increased with increased Bi2O3 ... al (1983) Tetracoordinated, Penta-Coordinated and Hexacoordinated Aluminum - Nmr and X-Ray-Diffraction Studies of the Complexes of Ethylenediamine with Aluminum Isopropoxide and Its Fluoro Analogs ... Advances in Solid- State Lasers: Development and Applications M Y Peng, D P Chen, et al (2007) Bismuth-doped zinc aluminosilicate glasses and glassceramics with ultra-broadband infrared luminescence...
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Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 4 doc
Ngày tải lên :
21/06/2014, 10:20
... stress-induced birefringent and 126 Advances in Solid- State Lasers: Development and Applications a strong thermal lensing in laser rods Nevertheless, efficient birefringent compensation in an ... Advances in Solid- State Lasers: Development and Applications 1908-nm line In the last part of characterisation in a free-running regime, we have measured the beam profiles in far field in the focal ... rain and lightning strikes To achieve this, monitoring of the flow of ice-crystals in the cloud is effective Local and steep weather changes such as heavy rain and lightning strikes occur in...
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Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 5 docx
Ngày tải lên :
21/06/2014, 10:20
... standards, and widely used in the industry As the time standard has the higher stability and uncertainty, the dimensional metrology will have better uncertainty by linking length to time standards ... D Spinhirne,a nd V S Scott, “Global monitoring of clouds and aerosols using a network of micro-pulse lidar systems”, in Lidar Remote Sensing for Industry and Environmental Monitoring, U N Singh, ... though impulse discharge in air”, IEEJ Transactions on Electrical and Electric Engineering, in press T Shiina, E Minami, M Ito, and Y Okamura, "Optical Circulator for In- line Type Compact Lidar",...
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Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 6 pot
Ngày tải lên :
21/06/2014, 10:20
... function of the grazing incidence internal angle θ corresponding to a full pump power and maximum seeding injection clipping the beam, hence maximising the small-signal gain in the first unsaturated ... face and absorbed by the crystal), αP = αP0 / (1 + IP / ISP) and ISP is the pump absorption saturation intensity (Bermudez et al., 2002) Inserting Eqs (2) and (3) into Eq (1) and integrating, ... amplifier chains 2.4 Bandwidth limitation and gain narrowing The most important of limitations arising from the finite bandwidth of the amplifier concern single- or multi-pulse amplification in pulsed...
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Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 10 pdf
Ngày tải lên :
21/06/2014, 10:20
... coupling modifying the beam divergence and even the compression of the initial pulse Supposing that the initial pulse has gaussian shapes in space and spectral amplitude, and is “chirped” as Ein ... − ω0 , where φ ( Ω ) = φ (ω ) and θi and θd are the angles of incidence and diffraction respectively, and p the grating line spacing The electric field profile in the focal plane of the lens ... spatial profile on the grating Minimizing the space-time coupling by using spatially large input pulses, discrete Fourier sampling and pulse replica cannot be avoid as the following analysis (suggested...
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Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 11 pptx
Ngày tải lên :
21/06/2014, 10:20
... in Solid- State Lasers: Development and Applications A simpler layout consists in performing the wavelength scanning by rotating the grating around an axis passing through the grating center and ... profiles & phases for the (a) linear gradient and (b) triangle gradient temperature in Fig (b) and (a) 12 Incident In uniform In linearily shaped In triangle shaped Intensity(a.u) 10 -30 -20 -10 ... effect, beam defocusing due to the plasma, pulse selfsteepening, and beam diffraction The propagating pulse suffers significant reshaping in both time and space domain This reshaping process will lead...
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Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 12 pptx
Ngày tải lên :
21/06/2014, 10:20
... 432 Advances in Solid- State Lasers: Development and Applications where S1 and S2 are, respectively, the distances G1–P2 and P3–G2 For S < 2p, G1 is imaged behind G2 and the resulting GDD is positive ... classical mount and, once the grating groove density has been selected, it gives minimum temporal response at grazing incidence Both single- and double-grating monochromators in the off-plane ... pulse This class of instruments plays an important role for the photon handling and conditioning of future ultrashort sources 436 Advances in Solid- State Lasers: Development and Applications Acknowledgment...
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Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 13 pptx
Ngày tải lên :
21/06/2014, 10:20
... of including spatially and temporally 502 Advances in Solid- State Lasers: Development and Applications dependent ionisation within the capillary waveguide However further developments including ... Kingdom of Great Britain and Northern Ireland Introduction The ability to image matter on the microscopic scale is of fundamental importance to many areas of research and development including ... Advances in Solid- State Lasers: Development and Applications Fig Laser source used to generate a 10 fs train of sub-femtosecond duration pulses in the XUV for scattering and diffraction imaging Also...
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Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 14 pdf
Ngày tải lên :
21/06/2014, 10:20
... sum is included over the N atoms ionizing in the laser focus incorporated as shown in Eqs 10 and 11 It is important to note that WSC–incoherent in the focal geometry case involves an incoherent ... Solid- State Lasers: Development and Applications fields having linear polarization in the x-direction (zeroth-order) and propagating in the +z direction (Davis, 1979; Salamin, 2007), (28) (29) ... stronger in intensity and higher in photon energy in the case of a linearly polarized laser The most different characteristics are the appearance of a large-interval modulation in the case of a linear...
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Advances in Solid-State Lasers: Development and Applications_1 doc
Ngày tải lên :
27/06/2014, 01:21
... Advances in Solid- State Lasers: Development and Applications Edited by Mikhail Grishin Intech IV Published by Intech Intech Olajnica 19/2, 32000 Vukovar, Croatia Abstracting and non-profit ... designed by Dino Smrekar Advances in Solid- State Lasers: Development and Applications, Edited by Mikhail Grishin p cm ISBN 978-953-7619-80-0 Preface Invention of the solid- state laser has initiated ... science and become an increasingly important tool for modern technology This book represents a selection of chapters exhibiting various investigation directions in the field of solid- state lasers and...
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Tiểu luận môn Bảo mật thông tin Security in Development and support process
Ngày tải lên :
04/05/2015, 23:36
... A.12.5.4 Rò rỉ thông tin (Information leakage) Control A.12.5.5.Thuê gia công phần mềm (Outsourced software) Security in Development and support process Duy trì an ninh thông tin hệ thống phần mềm ... 2005 ) Control 12.5.4 Rò rỉ thông tin (information leakage) Kiểm soát: hội dẫn đến việc rò rỉ (lộ) thông tin nên ngăn chặn Control 12.5.4 Rò rỉ thông tin (information leakage): Hướng dẫn triển ... phép + Hạn chế lạm dụng dịch vụ thông tin cá nhân Control 12.5.4 Rò rỉ thông tin (information leakage): số khuyến nghị kỹ thuật Control 12.5.4 Rò rỉ thông tin (information leakage): số khuyến nghị...
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Development and validation of analytical method for naftopidil in human plasma by LC–MSMS
Ngày tải lên :
02/09/2015, 13:48
... chromatograms, shown in Fig 4a and b, indicate that there was no interference with the analyte and IS from endogenous substances in the plasma 5.2.2 Linearity The linearity of the method was determined by ... analyte and the IS at retention times of 1.8 and 1.6 min, respectively A flow-rate of 0.500 mL/min produced good peak shapes and permitted a run-time to Internal standard is necessary for the determination ... Development and validation of analytical method for Naftopidil in human plasma by LC–MS/MS 649 for sample processing, and a high injection volume, but still no...
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Development and characterization of refractive solid immersion lens technology for far field integrated circuit faillure analysis using laser induced techniques
Ngày tải lên :
30/09/2015, 06:19
... cause This understanding can eventually lead to improved integrated circuit designs and reduction in development cycles through timely diagnosis of failures In manufacturing and applications, ... application in the microelectronics industry Failure Analysis (FA) is a critical element and basically involves performing a series of electrical and physical inspections to analyze and understand failures ... aplanatic point Schematic diagram of (a) conventional imaging, (b) backside imaging, (c) imaging using CRSIL and (d) imaging using an ARSIL Relationship between the field radius (horizontal) and the...
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Economic evaluation within the scope of the field development and application of the gas assisted gravity drainage (GAGD) process in an actual northern louisiana field
Ngày tải lên :
25/09/2016, 19:47
... royalty and are comprised of the operating costs (OPEX) and the capital expenditures (CAPEX), including depreciation, depletion and amortization allowances and tangible and intangible drilling costs ... GAGD process uses the natural tendency of the gas to rise to the top and the descent of the injected water to the bottom by injecting gas into the reservoir using (existing) vertical wells and ... thus displacing and draining oil and water to the horizontal producers at the bottom The use of horizontal producers increases the areal exposure to the reservoir thus leading to an increased well...
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Tìm thêm:
- hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam
- xác định các mục tiêu của chương trình
- xác định các nguyên tắc biên soạn
- khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn
- khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản
- khảo sát chương trình đào tạo gắn với các giáo trình cụ thể
- xác định thời lượng học về mặt lí thuyết và thực tế
- tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam
- điều tra đối với đối tượng giảng viên và đối tượng quản lí
- điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1
- khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam
- khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu
- nội dung cụ thể cho từng kĩ năng ở từng cấp độ
- xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct
- phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ
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- đặc tuyến hiệu suất h fi p2