... J. CHAMBERLAIN, Administrative Coordinator TANJA PILZAK, Manager, Program Operations CELESTE A. NAYLOR, Information Management Associate CHRISTINA O. SHIPMAN, Financial Officer SANDRA WILSON, ... March 1, 2009) CARMELA J. CHAMBERLAIN, Administrative Coordinator TANJA PILZAK, Manager, Program Operations CELESTE A. NAYLOR, Information Management Associate CHRISTINA O. SHIPMAN, Financial ... countermeasure has the capability for maintaining normal function for long durations in microgravity. Success in maintaining approximately normal homeostasis on the ISS would benefit astronauts traveling...
... National Laboratory,Lawrence Berkeley National Laboratory, Sandia National Laboratories, LosAlamos National Laboratory, National Renewable Energy Laboratory, ArgonneNational Laboratory, Oak ... DirectorRICHARD CAMPBELL, Program OfficerALAN CRANE, Program OfficerMARTIN OFFUTT, Program OfficerSUSANNA CLARENDON, Financial AssociatePANOLA GOLSON, Project AssistantANA-MARIA IGNAT, Project AssistantSHANNA ... analysis ofthe particulates indicated that the plasma was also effective in reducing the polycyclic aromatic content ofthe particulate matter. Such charac-teristics ofthe particulate matter are...
... the area can quickly obtain familiarity with keyideas and concepts ofthe topic, all in one place, acquiring a frameworkby which to understand related work and perhaps to start working in the area. ... that environment.” Context-aware pervasive computing is a study of pervasive computer systems (a combination of hardware andsoftware) 13 that are aware of context and can automatically adapt ... intelligently to what is perceived is an exciting,if not increasingly vital, addition to daily life and work. Whereas the idea of context has been studied in logic and the meaning of natural languagesentences,...
... behavior. Again, how-ever, we caution that we are presenting a thinkingtool, not an engineering tool. The seven levers are, atthis point, merely a framework for diagnosing andprobing the ... for cooperative behavior and collective actionwas informed by the insights of an expertgroup, including: Lada Adamic, Information Dynamics Lab,Hewlett-Packard LaboratoriesGene Becker, Strategic ... evolution of institutions of collective action. Ostrom has taken the lead in making the management principles for these institutions explicit, combining theory andempirical observation of real-world...
... clear that CEOs are beginning to recognise the scale ofthe challenge that they face in aligning sustainability with core business, and in creating the environment necessary for sustainable ... performance assessment Embedding sustainability into strategy and operations of subsidiaries Investing in training employees to manage sustainability Engaging in collaborations & partnerships ... game about investing in sustainable business, but that potential has yet to be realized.” 28Part FiveAccelerating the journey to thenew era of sustainability The 2010 UN Global Compact-Accenture...
... 1–4).There was minimal overlap of staining for FADDwith the early endosome marker early endosomeantigen 1 (EEA-1) in resting cells (Fig. 3B, panels1–3). Overlap of staining for FADD and EEA-1was, ... endosomes and cas-pase activation, our data indicate that CD95 triggeringinduces additional, plasma membrane proximal signals. The elucidation ofthe molecular pathways involved in connecting CD95 ... the cytoplasm is only ofa transient nature.Our data suggest a sequential model of signaling in which CD95 receptor activation generates early signalsat the plasma membrane that lead to the translocationof...
... [19]. In mammalian apop-tosis, caspase-8 and caspase-9 are known to be associ-ated with the mitochondrial pathway. Active caspase-8induces the release of mitochondrial apoptosis factors, in a ... [29,30]. The large-fragment-size DNA fragmentation and DNA ladderingare characteristics ofthe apoptotic nucleus, and the final DNA degradation step inthe autophagosome maycorrespond to the phagocytosis ... rRNA (mtLSUrRNA) gene: mtLSU-3, 5¢-TACAACAGATAGGGACCAA-3¢; and mtLSU-4, 5¢-CCTCCTAAAAAGTAACGG-3¢. The PCR products werecloned into the pBluescript II SK– vector (Stratagene Inc.,La Jolla, CA)...
... may mediate the enhancing effect of splicing onmRNA translation [34–36]. Rbm9, as a splicing factorinteracting with a PAP, may also participate in the translational enhancement mediated by introns.Indeed, ... (amino acids 48–269) and aminoacids 269–350 of hRbm9 are not able to mediate the binding. These data suggest that a domain surroundingamino acid 269 is important forthe interaction, or thatmost ... advice and assis-tance during the two-hybrid screen. We are grateful toNicola Minshall and Nancy Standart forthe tetheringassay constructs, and to Marvin Wickens and LabibRouhana forthe gifts...
... that none of these enzymes significantly decreased the amount of the stable c11aggregates. A similar observation wasmade after incubating the sample for 5 min at 95 °CinSDS-containing loading ... topographs recorded simultaneously in trace and in the retrace direction were observed, indicating that the scanning process did not in uence the appearance of the biological sample.AFM data analysis ... FEBS5¢-GGAGGAAATAAGCATATGGATATG-3¢ (forward),containing an NdeI site, and 5¢-CCTTTCAGGAAGCTTCCTCC-3¢ (reverse), containing a HindIII site. The PCRproduct and plasmid pt7-7 [25] were digested with thesetwo...
... that catalyzes the transformation of preginto androstadienol, a precursor inthe biosynthesis of Fig. 5. In uence of increasing concentrations of cyt b5on the relativeformation of androstadienol ... precisely, an increase of androsta-dienol formation was observed at a cyt b5/P450c17 ratio of 5 : 1 (Fig. 5). The activity reached a maximum at a ratio of 12 : 1. Thus, thein uence of human cyt ... Our results therefore demon-strate that human P450c17, as other enzymes ofthe classicalsteroidogenic pathway, is involved inthe biosyntheticpathway leading to the formation of androstenol.Keywords:...
... Herschel, a hautboy-player inthe band ofthe Hanoverian Guard, and was early trained to follow his father's profession. On the termination, however, ofthe disastrous campaign of 1757, his parents ... eccentricities and inclinations of their paths departed widely from the planetary type—that of Pallas, to take an extreme instance, making with the ecliptic an angle of nearly 35°. The minuteness of these ... it, as explanatory ofthe eccentric orbits of comets, the nebular theory of Laplace, thereby obtaining, as he said, " ;a complete view ofthe origin ofthe planetary system more conformable...
... children.NATIONAL ACADEMY ON AN AGING SOCIETYArthritisNATIONALACADEMY ON ANAGING SOCIETYNumber 5March 2000 A leading cause of disability in the United StatesArthritis is among the most common ... CONDITIONSCHALLENGES FORTHE21ST CENTURY: WHO HASARTHRITIS?SOURCE: National Academyon an Aging Society analysis of data from the 1994 NationalHealth Interview Survey.AGEGENDER63%FEMALE37%MALE46%65+1%0–1717%18–4436%45–64■ ... with arthritis also need helpwith instrumental activities of daily living,or IADLs. These include preparing meals,shopping, using the telephone, managingmoney, taking medications, and doing...