preoperative imaging of liver cancers hepatocellular carcinoma
Báo cáo y học: "Efficacy of Radiofrequency Ablation of Hepatocellular Carcinoma Associated with Chronic Liver Disease without Cirrhosis" pdf
... Percutaneous radiofrequency ablation of hepatocellular carcinoma as a bridge to liver transplantation Hepatology 2005;41:1130-37 Takano S,Yokosuka O, Imazeki F et al Incidence of hepatocellular carcinomain ... language revision of the manuscript Conflict of Interest The authors have declared that no conflict of interest exists References Bruix J, Sherman M Management of hepatocellular carcinoma Hepatology ... prospective study of 251patients Hepatology 1995;21:650-655 Otto G Heuschen U, Hofman WJ et al Survival and recurrence after liver transplantation versus liver resection for hepatocellular carcinoma: ...
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Báo cáo khoa học: "Differentiating the impact of anatomic and non-anatomic liver resection on early recurrence in patients with Hepatocellular Carcinoma" pps
... Long-term survival and pattern of recurrence after resection of small hepatocellular carcinoma in patients with preserved liver function: implications for a strategy of salvage transplantation Ann ... surgical management of HCC in cirrhotic patients, its use is limited by the shortage of donors [21] Hepatic resection remains the treatment of choice offering the possibility of cure, but the long-term ... recurrence is considered one of the most important factors that impact the prognosis of HCC patients [25] The present study attempts to determine the impact of the type of liver resection (anatomical...
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Identification and characterization of iron homeostasis related genes and HCC down regulated mitochondrial carrier protein (HDMCP), a novel liver specific uncoupling protein in human hepatocellular carcinoma (HCC
... et al Risk of hepatocellular carcinoma in patients with cirrhosis in Japan Analysis of infectious hepatitis viruses Cancer 1994;74:2234-2238 33 Anzola M Hepatocellular carcinoma: role of hepatitis ... al Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver Proc Natl ... during liver regeneration is not required for the liver to achieve all the hallmarks of development Furthermore, the observation of impaired liver regeneration occurring in patients with liver...
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Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"
... in human hepatocellular carcinoma cells In addition, this represents a novel approach for the identification of potential targets in the diagnosis and treatment of human hepatocellular carcinoma ... virus (HCV) infection , a leading cause of severe hepatitis that often develops into liver cirrhosis and hepatocellular carcinoma, the selective regulation of ethanol on STAU2 may represent an important ... permeability of the gut mucosa to endotoxins [43, 44] These factors are involved in ethanol-induced liver damage Thus, the direct injection of low concentration of ethanol for the treatment of hepatocellular...
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Báo cáo khoa học: MicroRNA-373, a new regulator of protein phosphatase 6, functions as an oncogene in hepatocellular carcinoma pdf
... assess the effect of miR373 on the proliferative capacity of HCC cells The colony formation rate of HepG2 cells after transfection with miR-373 ASOs was 30% lower than that of HepG2 cells transfected ... its expression MicroRNAs regulate a variety of cellular activities through regulation of the expression of target genes To determine the mechanism of miR-373-mediated cell cycle dysregulation ... overexpression of miR-373 reduced the PPP6C protein level by 70% (Fig 5C) To confirm the results obtained from the cell lines, we also examined the expression of PPP6C mRNA in 16 pairs of hepatocarcinoma...
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Báo cáo khoa học: HIP/PAP, a C-type lectin overexpressed in hepatocellular carcinoma, binds the RIIa regulatory subunit of cAMP-dependent protein kinase and alters the cAMP-dependent protein kinase signalling ppt
... Results Identification of the RIIa regulatory subunit of PKA as a partner of HIP/PAP In order to assess the biological consequences of HIP/PAP expression in hepatocellular carcinoma, we looked ... biological function of this protein in the liver is unknown To address this issue, we therefore looked for proteins capable of interacting with HIP/PAP in hepatocellular carcinoma cells By screening ... reticulum of rat liver: demonstration of different reactive forms of the phosphorylated intermediate J Biol Chem 260, 788–794 22 MacLennan, D.H., Rice, W.J & Green, N.M (1997) The mechanism of Ca2+...
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Báo cáo khoa học: MicroRNA-23b mediates urokinase and c-met downmodulation and a decreased migration of human hepatocellular carcinoma cells doc
... the development and progression of several types of malignant tumor An essential role of uPA and c-met in the migration and proliferation of human hepatocellular carcinoma (HCC) cells has been ... none of those considered (i.e size of the tumor, degree of differentiation, and the presence of pseudocapsule invasion) was related to miR-23b expression in HCC 3¢-UTR constructs Segments of the ... expression level of miR-23b The differentiated HuH6 and HepG2 cells showed a different profile of uPA and c-met expression, as well as of miR-23b The HuH6 cells, with undetectable levels of uPA and...
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báo cáo hóa học:" In vitro generation of cytotoxic and regulatory T cells by fusions of human dendritic cells and hepatocellular carcinoma cells" docx
... rate of hepatocellular carcinoma Hepatogastroenterology 2006, 53:409-414 Nishiguchi S, Shiom S, Nakatani S, Takeda T, Fukuda K, Tamori A, Habu D, Tanaka T: Prevention of hepatocellular carcinoma ... express full levels of costimulatory molecules and the maturation marker in the presence of HCCsp Effect of HCCsp on the phenotype of fusion cell preparations To assess the effects of HCCsp on DCs/tumor ... of fusion cells and have a negative impact in the stimulation of T cells To determine the induction of WT1-specitic CD8+ T cells, a pentameric assay of soluble class I MHC-peptide com- Page of...
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báo cáo hóa học:" Correlation between expression of p53, p21/WAF1, and MDM2 proteins and their prognostic significance in primary hepatocellular carcinoma" docx
... liver function, making the treatment of HCC more difficult than that of many other cancers Surgery, including transplantation, remains the only potential curative modality for HCC Prognosis of ... area of hepatocellular carcinoma (HCC) (A) Immunohistochemical staining for p53 (B), p21/WAF1 (C), and MDM2 (D) in HCC (Mag ×400) Page of (page number not for citation purposes) Journal of Translational ... non-small cell lung carcinoma [24] and cutaneous squamous cell carcinoma [25], but is decreased in colorectal carcinoma [26] and ovarian carcinoma [27] Table 3: The expression of p53, p21/WAF1,...
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Báo cáo hóa học: " High expression of transcriptional coactivator p300 correlates with aggressive features and poor prognosis of hepatocellular carcinoma" doc
... alterations of tumor cells and contributes to the growth of prostate carcinoma and is a predictor of aggressive features of this cancer [14,15] Up to date, the clinicopathologic/prognostic implication of ... of p300 could be detected in 60/123 (48.8%) of HCCs, in 6/87 (6.9%) of adjacent liver tissues with cirrhosis and in 2/36 (5.6%) of adjacent normal liver tissues without cirrhosis, respectively ... frequency of cases with high expression of Ki67 was significantly larger in carcinomas with a high expression of p300 (32/56 cases, 57.1%) than in those cases with a low expression of p300 (18/62...
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báo cáo khoa học: "Surgical outcome of hepatocellular carcinoma patients with biliary tumor thrombi" ppt
... Rodés J, EASL Panel of Experts on HCC: Clinical management of hepatocellular carcinoma Conclusions of the Barcelona-2000 EASL conference European Association for the Study of the Liver J Hepatol ... DeMatteo RP: Outcome of partial hepatectomy for large (> 10 cm) hepatocellular carcinoma Cancer 2005, 104:1948-1955 11 Edmondson HA, Steiner PE: Primary carcinoma of the liver A study of 100 cases among ... Cooperative Study Group on Hepatocellular Carcinoma: Critical appraisal of the clinical and pathologic predictors of survival after resection of large hepatocellular carcinoma Arch Surg 2005,...
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báo cáo khoa học: "Analysis of the recurrence risk factors for the patients with hepatocellular carcinoma meeting University of California San Francisco criteria after curative hepatectomy" pot
... stage hepatocellular carcinoma: resection versus liver transplantation Oncology 2008, 75(Suppl 1):124-128 10 Fong Y, Sun RL, Jarnagin W, Blumgart LH: An analysis of 412 cases of hepatocellular carcinoma ... A: Liver transplantation for hepatocellular carcinoma World Journal of Gastroenterology 2009, 15:5511-5516 Yi NJ, Suh KS, Kim T, Kim J, Shin WY, Lee KU: Current role of surgery in treatment of ... in hepatocellular carcinoma gender disparity International Journal of Cancer 2010, 127:499-504 22 Kalra M, Mayes J, Assefa S, Kaul AK, Kaul R: Role of sex steroid receptors in pathobiology of hepatocellular...
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báo cáo khoa học: "Influence of viral hepatitis status on prognosis in patients undergoing hepatic resection for hepatocellular carcinoma: a meta-analysis of observational studies" ppt
... HCC = hepatocellular carcinoma; B-HCC = hepatitis B-related hepatocellular carcinoma; C-HCC = hepatitis C-related hepatocellular carcinoma; NBNC-HCC = no infection of HBV or HCV related hepatocellular ... Suko H: Correlation of clinical characteristics with detection of hepatitis B virus × gene in liver tissue in HBsAg-negative, and HCV-negative hepatocellular carcinoma patients Liver 2002, 22:374-9 ... hepatocellular carcinoma; C-HCC = hepatitis C-related hepatocellular carcinoma; NBNC-HCC = no infection of HBV or HCV related hepatocellular carcinoma; AFP = alpha fetoprotein; ALT = alanine aminotransferase;...
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báo cáo khoa học: "Ex vivo hepatic venography for hepatocellular carcinoma in livers explanted for liver transplantation" ppsx
... metastasis of human hepatocellular carcinoma Hepatogastroenterology 2004, 51:1121-1123 13 Endo K, Terada T: Protein expression of CD44 (standard and variant isoforms) in hepatocellular carcinoma: ... hepatocellular carcinoma: a retrospective study of 435 patients Hepatology 1998, 28:751-755 Llovet JM, Bru C, Bruix J: Prognosis of hepatocellular carcinoma: the BCLC staging 11 classification Semin Liver ... Langnas AN: Liver transplantation for hepatocellular carcinoma: an update J Natl Compr Canc Netw 2006, 8:762-767 Eguchi S, Kanematsu T: Liver Cancer Study Group of Japan: Comparison of the outcomes...
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báo cáo khoa học: "Evaluation of the new AJCC staging system for resectable hepatocellular carcinoma" pptx
... encapsulation, Hepatocellular carcinoma, Partial hepatectomy, TNM-7 Background Hepatocellular carcinoma (HCC) is one of the most common cancers observed world-wide [1-2] This form of cancer is ... selection of surgical treatment for hepatocellular carcinoma Liver Transpl 2005, 11:1086-1092 Zhou L, Rui JA, Wang SB, Chen SG, Qu Q: Prognostic factors of solitary large hepatocellular carcinoma: ... culinaris agglutinin-reactive fraction of 34 alpha-fetoprotein as a marker of prognosis and a monitor of recurrence of hepatocellular carcinoma after curative liver resection Ann Surg Oncol 2011,...
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Báo cáo khoa học: "Human vascular adhesion proteın-1 (VAP-1): Serum levels for hepatocellular carcinoma in non-alcoholic and alcoholic fatty liver disease" pdf
... Rodés J: EASL Panel of Experts on HCC Clinical management of hepatocellular carcinoma Conclusions of the Barcelona-2000 EASL conference European Association for the Study of the Liver J Hepatol 2001, ... Association for the Study of the liver [18] Pre-operative 55 patients with HCC, all of whom had cirrhosis, were selected for study Of these, 33 patients had alcoholic liver disease and 22 patients ... 22 patients non-alcoholic fatty liver disease The diagnosis of non-alcoholic fatty liver disease cirrhosis was made in patients who had clinical features and liver biopsies compatible with non-alcoholic...
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Báo cáo khoa học: "Solitary skull metastasis as initial manifestation of hepatocellular carcinoma" doc
... Figure Magnetic resonance imaging (MRI) of the skull metastasis from hepatocelluar carcinoma Magnetic resonance imaging (MRI) of the skull metastasis from hepatocelluar carcinoma A) T1-weighted ... adults, of which 60% are from breast and lung carcinoma, although hematogenous skull metastases can be caused by nearly all types of tumors [11] Because of the wide spectrum of primary cancers ... strong enhancement of the tumor Page of (page number not for citation purposes) World Journal of Surgical Oncology 2008, 6:66 http://www.wjso.com/content/6/1/66 Figure of the liver rate, low-density,...
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Báo cáo khoa học: "Major liver resection for hepatocellular carcinoma in the morbidly obese: A proposed strategy to improve outcome" doc
... involved segment IV of the left lobe and segments V and VIII of the right lobe of the liver, partially occluding the proximal part of the common bile duct and causing moderate dilatation of the intrahepatic ... for less than 20% of the total liver volume and less than 0.45% of the patient's total body weight Surgical resection was initially ruled out because of a small-for-size remnant liver and abnormal ... of segments II and III A volumetric study performed weeks after PVE showed that the caudate lobe and segments II and III accounted for 33% of the total liver volume Figure of left lobe1 the liver...
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Báo cáo khoa học: "FDG-PET/CT imaging for staging and radiotherapy treatment planning of head and neck carcinoma" pps
... range of solid cancers [3,4], including head and neck carcinoma [5,6] FDG-PET, however, requires careful correlation with structural images for precise tumor localization because of lack of anatomical ... injection of about MBq of FDG per kg of body weight, patients were rested for a period of about 60 minutes in a comfortable chair Emission images ranging from the proximal femur to the base of the ... acquired for 2–3 minutes per bed position Field of view was of 50 cm with a matrix of 512 × 512 pixels for CT and of 128 × 128 for PET The proc- Page of (page number not for citation purposes) Radiation...
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báo cáo khoa học: "Transcription factor c-Myb promotes the invasion of hepatocellular carcinoma cells via increasing osteopontin expression" ppsx
... J: Hepatocellular carcinoma Lancet 2003, 362:1907-1917 Tang ZY, Ye SL, Liu YK, Qin LX, Sun HC, Ye QH, Wang L, Zhou J, Qiu SJ, Li Y, et al: A decade’s studies on metastasis of hepatocellular carcinoma ... metastatic potential expressed high level of OPN (Figure 1A, C) With > 2-fold or < 0.5-fold expression as the cutoff point, analysis of transcription factor profiles revealed that eleven transcription ... confirmed the difference of c-Myb mRNA expression in different cell lines Graph depicted relative expression of OPN mRNA normalized to that of GAPDH The mRNA expression of c-Myb in HCCLM6 was used...
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