prenatal diagnosis of the hemoglobinopathies

báo cáo khoa học: " Prenatal diagnosis of fetal aneuploidies: post‑genomic developments" pps

Ngày tải lên : 11/08/2014, 12:20

... as it would seem because of the incredible complexity of the plasma proteome, which contains peptides derived from every tissue of the body Furthermore, the presence of very abundant proteins, ... translation Page of of this approach into the clinic are the cost of the instruments, the reagents and the experimental analysis, and the length of time taken to perform the subsequent bioinformatic analysis ... turnover of the placental trophoblast tissue The use of placentally derived cell-free fetal DNA has been shown to be useful for the detection of fetal loci that are Page of completely absent from the...

5
218
0

Báo cáo y học: " Challenges in the prenatal and post-natal diagnosis of mediastinal cystic hygroma: a case report" docx

Ngày tải lên : 11/08/2014, 21:22

... postoperatively We offer an overview of the role of imaging and suggest that both the local anatomy and the organisation of the cystic structure be borne in mind in the assessment of these mediastinal ... rewrote the first draft of the discussion from the second author and edited the submission after receiving the reviewers' comments SAR wrote the first draft of the discussion SN obtained the echocardiogram ... possibility of sporadic compression of the left phrenic nerve resulting from its anatomical location of the lesion, coupled with the cystic nature of the lesion, would be reason enough for the lesion...

5
369
0

biological model of fetomaternal haemorrhage for the development of first trimester non invasive prenatal diagnosis

Ngày tải lên : 11/09/2015, 16:03

... methods These procedures carry the risk of miscarriage and therefore limit the uptake of prenatal diagnosis for these conditions Hence, there is a need for a risk-free non-invasive method for prenatal ... risk of pregnancy loss compared with the mid-trimester amniocentesis The primary concern for patients undergoing prenatal testing is the chance that the procedure will lead to the loss of the ... gestational age, scanning policy, skill of the operator, type of machines being used and the type of anomalies included in the evaluation Currently, the diagnosis of chromosomal, monogenic disorders...

236
315
0

Báo cáo y học: " the Value of Serum Biomarkers (Bc1, Bc2, Bc3) in the Diagnosis of Early Breast Cancer"

Ngày tải lên : 25/10/2012, 11:15

... since none of them alone is useful for the majority of the BC and none of them is specific for cancer or breast tissues No biomarker has been suggested to date for the early diagnosis of BC (24) ... evaluate the actual performance of these markers Jinang Li, from the John Hopkins Hospital, is the first to explore proteomics in early diagnosis of BC, who also enabled the advance of proteomics ... Med Sci 2011, The results of the present study and the other three studies did not fully confirm each other Several hypotheses may be suggested to explain these differences First of all, Li’s...

8
584
0

Tài liệu Role of diffusion-weighted imaging in the diagnosis of gynecological diseases pdf

Ngày tải lên : 13/02/2014, 06:20

... factor of 2) Imaging time of DWI was 90 s for 20 slices Detection of uterine malignancy The ADC values of uterine cancers are lower than of normal tissue On the other hand, in sarcomas the ADC ... in the diagnosis of intracranial epidermoid cyst [50] Detecting the keratinoid substance by means of DWI and the ADC value may be useful and serve as an adjunctive tool to ensure the accuracy of ... respectively These lymph nodes are predicted as metastases Another lymph node is noted in the right (arrowhead) The absolute ADC value of the lymph node is 0.95×10–3 mm2/s; therefore, the relative...

16
830
0

**A COMPARATIVE STUDY OF THE DIAGNOSIS OF PULMONARY TUBERCULOSIS USING CONVENTIONAL TOOLS AND POLYMERASE CHAIN REACTION* pot**

Ngày tải lên : 06/03/2014, 04:20

... available for comparison of the performance of the individual tests, an analysis of results was done using a variety of standards Efficiency of microscopy, culture and PCR in terms of sensitivity, specificity, ... diagnosed as not having tuberculosis, the PCR profile of the individual had changed markedly, suggesting an increase in the bacterial load in the sputum Only seven of the 17 cases i.e those who took ... considered as true cases of tuberculosis, even though the other six could be rated as highly probable cases of tuberculosis (Table 1B) Table summarizes the final diagnosis of tuberculosis made in...

8
524
0

New ESPGHAN guidelines for the diagnosis of Coeliac Disease in Children and Adolescents pptx

Ngày tải lên : 22/03/2014, 09:20

... same low levels Conclusions The new guidelines will offer the option of omitting biopsies in selected cases with symptoms suggestive of CD without increasing the risk of misclassification Preconditions ... individuals  Discourage the use of classical vs non-classical, typical vs atypical  Discourage the use of the term latent CD Ludvigsson et al Gut 2012 ESGPHAN member Questionnaire 85 % of those who are ... (Marsh 0) are often of low titre (

33
537
0

Accuracy of Clinical Signs in the Diagnosis of Pulmonary Tuberculosis: Comparison of Three Reference Standards Using Data from a Tertiary Care Centre in Rwanda doc

Ngày tải lên : 22/03/2014, 18:20

... probability of each test pattern for the hypothetical disease, the prevalence of the hypothetical disease, and the diagnostic sensitivity and specificity Different models can be tested for “fit”: the ... independence of the manifest variables L2: the likelihood ratio chi-squared statistic is used to assess how well the model fits the data It indicates the amount of the relationship between the variables ... model; the larger the value, the poorer the model fits the data As a rule of thumb, a good fit is provided by a model when the L2 for that model is not substantially larger than the degrees of freedom...

7
506
0

Diagnosis, Evaluation, and Management of the Hypertensive Disorders of Pregnancy pot

Ngày tải lên : 28/03/2014, 14:20

... be measured with the woman in the sitting position with the arm at the level of the heart (II-2A) An appropriately sized cuff (i.e., length of 1.5 times the circumference of the arm) should be ... as the objective of statin therapy is to decrease long-term cardiovascular risk, the potential risks of statin therapy (over the nine months of pregnancy) may outweigh the potential benefits of ... Of note, the protocol for women in the MgSO4 arm of the largest of these trials, the Collaborative Eclampsia Trial, did not include administration of benzodiazepines for seizure termination The...

52
561
0

Báo cáo hóa học: " Validity and reliability of the Spanish version of the DN4 (Douleur Neuropathique 4 questions) questionnaire for differential diagnosis of pain syndromes associated to a neuropathic or somatic component" docx

Ngày tải lên : 18/06/2014, 22:20

... 100% 0% > 10 Cutoff point A score > points in the sum of the 10 items of the DN4 questionnaire resulted in the best discriminant cut-off point for the overall sample Cut-off point in the DN4 questionnaire ... item and a score of to each negative item The total score is calculated as the sum of all 10 items, and the cut-off value for the diagnosis of neuropathic pain is a total score of 4/10 All questions ... index, the positive (PPV) and negative predictive value (NPV), the kappa coefficient of agreement with the diagnosis according to the standard criterion or reference diagnosis, and the area under the...

10
532
0

Báo cáo sinh học: " Shell Vial culture Assay for the rapid diagnosis of Japanese encephalitis, West Nile and Dengue-2 viral encephalitis" pdf

Ngày tải lên : 19/06/2014, 08:20

... [14] The rapidity of the technique without any compromise on sensitivity has made SVC very popular in the field of clinical virology The same technique has been employed for the identification of ... *Four out of fifty patients included in the study left the hospital against medical advice, the clinical outcome of whom is not known Hence, these cases were excluded from the analysis of clinical ... Among the 50 patients included in the study, (8%) patients left against medical advice, so the clinical outcome of these cases is not known Out of the remaining 46 (92%), 16(34.8%) expired and the...

7
454
0

báo cáo hóa học:" Shell Vial culture Assay for the rapid diagnosis of Japanese encephalitis, West Nile and Dengue-2 viral encephalitis" pdf

Ngày tải lên : 20/06/2014, 04:20

... [14] The rapidity of the technique without any compromise on sensitivity has made SVC very popular in the field of clinical virology The same technique has been employed for the identification of ... *Four out of fifty patients included in the study left the hospital against medical advice, the clinical outcome of whom is not known Hence, these cases were excluded from the analysis of clinical ... Among the 50 patients included in the study, (8%) patients left against medical advice, so the clinical outcome of these cases is not known Out of the remaining 46 (92%), 16(34.8%) expired and the...

7
547
0

báo cáo hóa học:" Validity and reliability of the Spanish version of the DN4 (Douleur Neuropathique 4 questions) questionnaire for differential diagnosis of pain syndromes associated to a neuropathic or somatic component" pdf

Ngày tải lên : 20/06/2014, 16:20

... 100% 0% > 10 Cutoff point A score > points in the sum of the 10 items of the DN4 questionnaire resulted in the best discriminant cut-off point for the overall sample Cut-off point in the DN4 questionnaire ... item and a score of to each negative item The total score is calculated as the sum of all 10 items, and the cut-off value for the diagnosis of neuropathic pain is a total score of 4/10 All questions ... index, the positive (PPV) and negative predictive value (NPV), the kappa coefficient of agreement with the diagnosis according to the standard criterion or reference diagnosis, and the area under the...

10
489
0

Báo cáo hóa học: " Evaluation of the diagnostic indices and clinical utility of qualitative cardiodetect® test kit in diagnosis of ami within 12 hours of onset of chest pain in the emergency department" pptx

Ngày tải lên : 20/06/2014, 23:20

... department setting The subjective nature of the reports of the patients about the exact onset of their ischemic symptoms may potentially overestimate or underestimate the duration of their ischemic ... improved the sensitivity, specificity, PPV, and NPV of the test, especially during the first h after the onset of chest pain The diagnostic accuracy of the repeat test was also superior to the Cardio ... College of Cardiology Committee (ESC/ACC) for the Redefinition of Myocardial Infarction published new criteria for the diagnosis of AMI They proposed the use of cardiac troponin (I or T) as the most...

9
463
0

Báo cáo hóa học: " An international evaluation of ultrasound vs. computed tomography in the diagnosis of appendicitis" doc

Ngày tải lên : 20/06/2014, 23:20

... drafted the manuscript TZ conceived of the study from the Israeli standpoint, participated in the design of the study, and helped draft the manuscript SW conceived of the study from the United ... to the patient, US is often used as the primary modality for the workup of appendicitis These differences in practice patterns between the two countries pushed us to explore the possibility of ... diagnostic accuracy in the management of acute appendicitis without adverse events The message of these studies is the same: the positive predictive value of US is excellent; if the appendix is visualized...

7
451
0

báo cáo hóa học: " Diagnosis of invasive candidiasis in the ICU" pot

Ngày tải lên : 21/06/2014, 00:20

... the appreciation of the dynamics of colonization and/or of the combination of less specific risk factors [51] Colonization-based assessment of the risk of invasive candidiasis Documentation of ... dectin-1, a member of the C-type lectin family of receptors Activation of the signal transduction pathways downstream of these receptors ultimately lead to the production of a complex array of mediators, ... assessed the degree of colonization by measuring daily the colonization index defined as the ratio of the number of distinct body sites colonized with Page of 10 genotypically identical strains of...

10
669
0

Báo cáo nghiên cứu nông nghiệp " Improving the Quality of Diagnosis of Animal Disease in Vietnam " pot

Ngày tải lên : 22/06/2014, 13:20

... design The objective of the project was initiation of a basic training programme in gross and bacteriologic diagnosis at each of the Regional Veterinary Centres It meets the criteria of the CARD ... during planning of the workshops, was the acquisition of suitable teaching material at the time of the workshop The nature of diagnostic work is that it is unpredictable in terms of what will appear ... workshops was the staff at the centres, plus veterinarians from the Provincial centres Staff of the Regional Centres were considered to be the most important elements of the strategy, because they have...

14
428
0

ADVANCES IN THE DIAGNOSIS OF CORONARY ATHEROSCLEROSIS pot

Ngày tải lên : 27/06/2014, 18:20

... information on the extent of atheroma contained within the vessel wall or the functional significance of the stenosis which can only be inferred Both of these limitations can be overcome by the use of intravascular ... 22 Advances in the Diagnosis of Coronary Atherosclerosis the direct effects of TRAIL on each cellular component in the arterial wall We will then discuss how TRAIL can act on the cardiovascular ... speculate the impact of TRAIL on atherosclerotic lesions in vivo, although the in vitro findings clearly indicate the involvement of the TRAIL/TRAIL receptor system in atherogenesis In the next...

390
512
0

Báo cáo khoa học : Tissue Doppler imaging for the diagnosis of coronary artery disease ppt

Ngày tải lên : 29/06/2014, 11:20

... segments at peak stress The clinical utility of the method then depends on the magnitude of the increase from baseline to peak stress The same group addressed the diagnostic accuracy of tissue Doppler ... case that the two locations are getting closer there is myocardial shortening, and when they move apart there is lengthening Strain is calculated as the time integral of strain rate, most often using ... and the velocities within a myocardial segment is the net result of motion caused by contractions in that segment, motion due to tethering to other segments, and overall motion of the heart The...

9
467
0

DIAGNOSIS OF PREGNANCY AND PRENATAL CARE potx

Ngày tải lên : 05/08/2014, 16:20

... diameter of the outlet (PS) (normal 8–9.5 cm) The PS is the distance from the midpoint of the line between the ischial tuberosities to the external surface of the tip of the sacrum (the tip of the ... By grasping the coccyx between the fingers of the examining hand, with the other hand placed in the cleft between the buttocks, the direction of the coccyx, its degree of movement at the sacrococcygeal ... uteri on the abdomen, not the length of the uterus The superior ramus of the pubis, the umbilicus, and the xiphoid are the fixed reference points from which the height of the fundus is measured...

50
192
1