potential new theories playing a role in nutrition lifestyle change

PHYTOCHEMICALS – A GLOBAL PERSPECTIVE OF THEIR ROLE IN NUTRITION AND HEALTH potx

Ngày tải lên : 28/06/2014, 11:20

... Silveira, Antonio Marcos E Bezerra, Luzia Kalyne A M Leal and Glauce Socorro B Viana Chapter 18 General Introduction on Family Asteracea 375 Maha Aboul Ela, Abdalla El-Lakany and Mohamad Ali Hijazi ... rutin, naringin , hesperidin and chlorogenic (Fig 4) 2.5 Saponins The term saponin is derived from Saponaria vaccaria (Quillaja saponaria), a plant, which abounds in saponins and was once used as ... hydrolysable tannins include theaflavins (from tea), daidezein, genistein and glycitein (Fig 5) Tanninrich medicinal plants are used as healing agents in a number of diseases In Ayurveda, formulations...

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Tài liệu Báo cáo khoa học: Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen pdf

Ngày tải lên : 18/02/2014, 04:20

... with a full-length furin cDNA, were permeabilized and stained with polyclonal antibodies against furin and GRASP55 Arrows show examples of membrane compartment containing GRASP55 and furin Scale ... receptor interacting protein (GRIP1) [55] Role of GRASP55 in MT1-MMP activation or inactivation no afterpotential D (INAD) protein [56] However, it can also be a PDZ-independent mechanism, as for example ... Barr and colleagues [35] GRASP55F in pCDNA3.1 Zeo+ contained a C-terminal FLAG tag Full-length GRASP55, GRASP55 PDZ1 (amino acids 1–107), GRASP55 PDZ2 (amino acids 84–172) and GRASP55 region (amino...

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Tài liệu Báo cáo khoa học: Differentiation stage-dependent preferred uptake of basolateral (systemic) glutamine into Caco-2 cells results in its accumulation in proteins with a role in cell–cell interaction pptx

Ngày tải lên : 20/02/2014, 01:20

... Glutamine incorporation in Caco-2 proteins determining the relative uptake of glutamine; (b) by searching for changes in the intestinal proteome; and (c) by examining glutamine incorporation into ... cytoplasmic proteins that can bind to the membrane surface in response to elevations in intracellular calcium [45] Annexin A2 is an F-actin binding protein and participates in the formation of ... the alpha-actinin protein family, alpha-actinin 1, has been shown to be involved in cadherin-mediated cell–cell adhesion via alpha-catenins in adherens junctions of epithelial cells [53] The fact...

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Peptidylarginine deiminase (PAD) is a mouse cortical granule protein that plays a role in preimplantation embryonic development docx

Ngày tải lên : 05/03/2014, 17:20

... determine that a putative signal peptide and a cleavage site exist in ePAD and AAH53724 (an egg and embryo abundant peptidylarginine deiminase), indicating they are likely secreted proteins (Fig arrow) ... cortical granules contain PAD To ascertain if mouse cortical granules contain PAD, antibodies made against mouse ePAD and human recombinant PAD V (anti-PAD V (N)) were used to label in vivo matured ... PAD and LCA-binding cortical granule components in in vivo Confocal Confocal scanning laser micrographs comparing distribution of PAD and LCA-binding cortical granule components in in vivo matured...

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Báo cáo khoa học: No evidence for a role in signal-transduction of Na+/K+-ATPase interaction with putative endogenous ouabain potx

Ngày tải lên : 23/03/2014, 17:21

... larger changes in intracellular Na+ and Ca2+ may thus be the result of a ouabain interaction with subpopulations of Na+/K+ATPase [27] An overall increase in intracellular Na+ was seen in the ... another group in collaboration with Hamlyn [21] by means of two independent assays, a radioimmunoassay using an anti-ouabain Ig and an enzymatic assay using ouabain-sensitive Na+/K+ATPase from dog ... latter may have a sublocalization critical for the observations looking at ouabain as a signal-transducer Experiments pointing to a pivotal role of ouabain in signal-transduction In the following,...

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Báo cáo Y học: Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation? ppt

Ngày tải lên : 23/03/2014, 21:20

... 5357 an anabolic stimulus, may largely induce increased translation across the board of mRNAs that are already actively being translated How could increased phosphorylation of eIF4E actually inhibit ... REGULATED PHOSPHORYLATION In higher animals – mammals and insects (at least in Drosophila) – eIF4E is a phosphoprotein It is phosphorylated by the MAP-kinase signal-integrating kinases Mnk1 and ... phosphorylation in mRNA translation, bearing in mind that the main mechanism governing the actual availability of eIF4E for translation is not its phosphorylation (which probably does not affect its binding...

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Báo cáo hóa học: " Targeting the inflammation in HCV-associated hepatocellular carcinoma: a role in the prevention and treatment" pptx

Ngày tải lên : 18/06/2014, 16:20

... treatment significantly attenuated some alterations (i.e increased levels of aspartate transaminase, alanine transaminase, alkaline phosphatase, acid phosphatase, lactate dehydrogenase, gamma-glutamyltransferase, ... (TIRdomain-containing adapter-inducing interferon-b) joining the RIG-I/MDA5 pathway In the other pathway, TLR7 senses single-strand HCV RNA and via the MyD88 adaptor protein activates IRAK4/IRAK1 These kinases ... prodrug Int J Cancer 2009, 124(11):2520-7 90 Jagan S, Ramakrishnan G, Anandakumar P, Kamaraj S, Devaki T: Antiproliferative potential of gallic acid against diethylnitrosamineinduced rat hepatocellular...

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báo cáo hóa học:" Triple-Nucleoside Analog Antiretroviral Therapy: Is There Still a Role in Clinical Practice? A Review" docx

Ngày tải lên : 20/06/2014, 08:20

... Montaner J, et al.: Abacavir-lamivudinezidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: A randomized equivalence trial JAMA 2001, 285:1155-1163 Abstract ... interaction Nonthymidine-Containing ("TAM-Sparing") t-NRTI Regimens as Initial ART Clinical trials that have investigated the use of TDF as part of the NRTI backbone of an ART regimen among treatment-naive ... 27 Ruane P, Mendonca J, Timerman A, et al.: Kaletra vs nelfinavir in antiretroviral-naive subjects: Week 60 comparison in a phase III, blinded, randomized clinical trial Program and abstracts...

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Báo cáo khoa học: "Pim-1 A serine/threonine kinase with a role in cell survival, proliferation, differentiation and tumorigenesis" potx

Ngày tải lên : 07/08/2014, 15:20

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Báo cáo y học: "Do the pleiotropic effects of statins in the vasculature predict a role in inflammatory diseases" pdf

Ngày tải lên : 09/08/2014, 06:22

... states beyond atherogenesis Sparrow and colleagues demonstrated that simvastatin had a comparable antiinflammatory effect to that of indomethacin in the carrageenan-induced foot pad oedema inflammatory ... studies are emerging In a murine model of allergic asthma, we recently showed potential benefits of statin therapy on inflammatory airway disease After priming and intra-nasal ovalbumin challenge, ... reductions in inflammatory cell infiltrate and eosinophilia in bronchoalveolar lavage fluid were observed with both oral and intraperitoneal administration of simvastatin [36] Continuing studies are addressing...

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Báo cáo y học: "Endogenous and exogenous stem cells: a role in lung repair and use in airway tissue engineering and transplantation" pdf

Ngày tải lên : 10/08/2014, 05:21

... Komura M, Komura H, Kanamori Y, Tanaka Y, Suzuki K, Sugiyama M, Nakahara S, Kawashima H, Hatanaka A, Hoshi K, Ikada Y, Tabata Y, Iwanaka T: An animal model study for tissue-engineered trachea fabricated ... 82 Omori K, Tada Y, Suzuki T, Nomoto Y, Matsuzuka T, Kobayashi K, Nakamura T, Kanemaru S, Yamashita M, Asato R: Clinical application of in situ tissue engineering using a scaffolding technique ... engineers should pay special attention to the fabrication of biologically active scaffolds and matrices capable of fulfilling natural properties of the airway ECM, for example, by maintaining and...

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báo cáo khoa học: " Do mitochondria play a role in remodelling lace plant leaves during programmed cell death?" pps

Ngày tải lên : 11/08/2014, 11:21

... by asterisk) and showed absolutely no staining (Figure 3J and 3K) These mitochondria appeared to have dramatically degraded cristae and nearly indistinguishable membranes via TEM imaging and also ... significant decrease in perforation formation within the lace plant via CsA application indirectly indicates that the PTP pathway may play a role in cellular death within this system Although the involvement ... stages (M1M4) based on their location in a window stage leaf areole Our findings also indicate that within a single areole of a stage (window stage) leaf a gradient of TUNEL-positive nuclei staining...

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Báo cáo khoa học: "Herpes simplex virus type 2 tegument protein UL56 relocalizes ubiquitin ligase Nedd4 and has a role in transport and/or release of virions" ppt

Ngày tải lên : 12/08/2014, 04:20

... suggests that the interaction of the two proteins is dynamic and transient Given that Nedd4 participates in many cellular trafficking activities including protein sorting and viral budding, UL56 can ... analysis and review of the manuscript YN performed project planning, participated in the data analysis and helped to draft the manuscript All authors read and approved the final manuscript Weissman AM: ... dynamics and signaling PLoS One 2008, 3:e1487 Hatakeyama S, Jensen JP, Weissman AM: Subcellular localization and ubiquitin-conjugating enzyme (E2) interactions of mammalian HECT family ubiquitin...

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báo cáo khoa học: " Co-expression and promoter content analyses assign a role in biotic and abiotic stress responses to plant natriuretic peptides" pptx

Ngày tải lên : 12/08/2014, 05:20

... physiological role of AtPNP -A in A thaliana a T-DNA insertion mutant, that is available from SALK, could be used Phenotyping this mutant in response to SA-inducing abiotic and biotic stresses as well as ... Kamiya A, Nakajima M, Enju A, Sakurai T, Satou M, Akiyama K, YamaguchiShinozaki K, Carninci P, Kawai J, Hayashizaki Y, Shinozaki K: Monitoring the expression pattern of around 7,000 Arabidopsis ... documenting induction of AtPNP -A expression in SA-mediated natural developmental and stress activated processes which both culminate in cell death indicating that AtPNP -A may be involved in these...

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Báo cáo y học: "A role for age-related changes in TGFβ signaling in aberrant chondrocyte differentiation and osteoarthritis" ppt

Ngày tải lên : 12/08/2014, 11:22

... Iida A, Sudo A, Miyamoto Y, Fukuda A, Mabuchi A, Kotani A, Kawakami A, Yamamoto S, Uchida A, Nakamura K, Notoya K, Nakamura Y, Ikegawa S: An aspartic acid repeat polymorphism in asporin inhibits ... medial tibia at an age of months and was 18 in 1-year-old animals The lateral tibia showed a ratio increase from to in the same period Clearly an increased ALK1/ALK5 ratio in chondrocytes is associated ... cytokines have been suggested to play a dominant role in OA Chondrocytes can be stimulated by catabolic cytokines to release cartilage degradation products, ultimately leading to damage A cytokine...

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Báo cáo y học: "bench-to-bedside review: Endothelial cell dysfunction in severe sepsis: a role in organ dysfunction" pdf

Ngày tải lên : 12/08/2014, 19:22

... C, Windsor A, Schwartz M: Circulating ICAM-1 is increased in septic shock Am J Respir Crit Care Med 1995, 151:1420-1427 53 Watanabe S, Mukaida N, Ikeda N, Akiyama M, Harada A, Nakanishi I, Nariuchi ... Szymanski LM: The suprapharmacologic dosing of antithrombin concentrate for Staphylococcus aureus-induced disseminated intravascular coagulation in guinea pigs: substantial reduction in mortality ... [17,60,61], have demonstrated attenuated acetylcholine-induced relaxation in vascular rings isolated from large arteries Apart from anatomical injuries, such abnormalities observed in these vessels may...

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Báo cáo khoa học: "Do statins have a role in preventing or treating sepsis" pptx

Ngày tải lên : 12/08/2014, 23:21

... statins may also ameliorate sepsis-induced coagulopathy [5,8,9] Another novel pathway may play an important role in attenuating sepsis-induced endothelial dysfunction Heme oxygenase (HO)-1 is an ... comorbidities and dissipated when the medication was discontinued There is growing interest among clinicians in the role that statins may play in preventing and treating serious infections If such an effect ... or placebo was initiated hours after sepsis induction, when profound hemodynamic alterations were already evident, survival time was again significantly extended in treated Available online http://ccforum.com/content/10/1/113...

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Báo cáo y học: "RNA interference has a role in regulating Drosophila telomeres" potx

Ngày tải lên : 14/08/2014, 16:21

... involved in transcriptional silencing in plants [12], Caenorhabditis elegans [13] and mammals [14], and in genome rearrangements in Tetrahymena [15], suggesting that RNAi is affecting Drosophila telomeres ... example, several aub alleles increased HeT -A expression in only a fraction of the ovaries, or sometimes only in some ovarioles in a single ovary Only in one case was HeT -A expression increased ... UTR, and gag while TART and Tahre have similar pol sequences but have very different 5’ UTR, 3’ UTR and gag sequences telomere maintenance in Drosophila, not a parasitic invader Savitsky and colleagues...

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radical abundance how a revolution in nanotechnology will change civilization k eric drexler

Ngày tải lên : 04/07/2014, 20:36

... music and violin-making, printing was a craft transmitted through a chain of apprentices And once again, in the world today there is a new industry based on machines that embody a radical break ... different kind of instrument Looking back, we can see a radical break that divides the past from the present Behind each violin stood a craftsman, a link in a chain spanning generations, each refining ... printed paper—an inconvenient undertaking when the nearest good library was miles away Today, affordable machines can deliver the content of a library’s journals to your lap in an instant—and...

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Báo cáo y học: " Vgf is a novel biomarker associated with muscle weakness in amyotrophic lateral sclerosis (ALS), with a potential role in disease pathogenesis"

Ngày tải lên : 03/11/2012, 10:52

... (HRP–conjugated anti–rabbit IgG, Santa Cruz Biotech, CA) The assay was developed using a stabilized HRP substrate All samples were analyzed in the linear range of the ELISA using over-expressed human ... complex was precipitated with 100 µl of goat anti rabbit IgG and 10 µl of normal rabbit serum (Peninsula Laboratories Inc., San Carlos, CA) dissolved in RIA buffer After incubating at room temperature ... unleashing NMDA and AMPA excitotoxic injury Thus a mechanism by which abnormal energy metabolism may have an influence on clinical ALS is through depletion of Vgf neuroprotection against spinal...

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