polyposis eroded polypoid hyperplasia inflammatory myoglandular polyps and polypoid prolapsing folds
báo cáo hóa học: " Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein b" potx
... 15 Figure Reduced proinflammatory gene expression in C/EBPb-/- mixed glial cultures Expression of pro -inflammatory (NOS2, IL-1b, IL-6 and TNFa) and anti -inflammatory (IL-4 and TGFb1) genes in ... comparison between LPS and LPS+IFNg effects on C/EBPb and on pro -inflammatory markers in glial cells We have observed that both LPS and LPS +IFNg induce similar increases in C/EBPb mRNA and protein levels ... Heurtaux T, Grandbarbe L, Morga E, Heuschling P: Characterization of the microglial phenotype under specific proinflammatory and anti -inflammatory conditions: Effects of oligomeric and fibrillar...
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Báo cáo y học: "Coexpression and interaction of CXCL10 and CD26 in mesenchymal cells by synergising inflammatory cytokines: CXCL8 and CXCL10 are discriminative markers for autoimmune arthropathie" doc
... such as astrocytes and keratinocytes [710] In addition, some Toll-like receptor ligands (e.g doublestranded RNA) stimulate the production of these CXCR3 ligands in leukocytes and fibroblasts [11,12] ... activity and BG collected patient samples PP, GO and JVD participated in the design of the study and wrote the manuscript SS, TL, MG, ES, MP, BG and JB revised the manuscript All authors read and ... cells and fibroblasts [1316] In endothelial cells and fibroblasts, however, most other cytokine combinations have not been evaluated for induction of CXCR3 ligands [17] Simultaneously, these inflammatory...
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Báo cáo y học: "Cigarette Smoke Exposure Alters mSin3a and Mi-2α/β Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function" ppt
... Northumberland, UK) Immunoblotting and immunoprecipitation was performed as previously described [26] All blots were stripped and re-probed for loading controls as previously described [26] ELISA and ... GR and HDAC [21,26] Both Mi-2 and mSin3a are critical components of transcriptional corepressor complexes and changes in their expression may lead to the alteration of both the formation and ... in HDAC-2 activity, Mi-2α and mSin3a are likely to impair the physiological regulation of pro -inflammatory gene expression and may contribute to a chronic enhanced inflammatory response seen...
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Báo cáo y học: "Cigarette Smoke Exposure Alters mSin3a and Mi-2α/β Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function" pdf
... Northumberland, UK) Immunoblotting and immunoprecipitation was performed as previously described [26] All blots were stripped and re-probed for loading controls as previously described [26] ELISA and ... GR and HDAC [21,26] Both Mi-2 and mSin3a are critical components of transcriptional corepressor complexes and changes in their expression may lead to the alteration of both the formation and ... in HDAC-2 activity, Mi-2α and mSin3a are likely to impair the physiological regulation of pro -inflammatory gene expression and may contribute to a chronic enhanced inflammatory response seen...
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Báo cáo y học: "Protein targets of inflammatory serine proteases and cardiovascular disease" pps
... proteases during thrombosis and inflammatory states PAR and PAR expressed in smooth muscle cells and PAR1 , PAR , and PAR expressed in macrophages activate inflammatory and proliferative pathways ... apoptosis, invasion, and migration of various mesenchymal, epithelial, and inflammatory cells Osteopontin is over-expressed in renal and cardiovascular cells during tissue remodeling and in inflammatory ... the context of PAR1 and PAR4 signaling in platelets and in animal models of thrombosis, inflammation, angiogenesis, and migration and invasion of cancer cells [14,41-43] PAR1 and PAR2 mediate various...
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Báo cáo y học: "Relationship between inflammatory markers, metabolic and anthropometric variables in the Caribbean type 2 diabetic patients with and without microvascular complications" pptx
... 3:17 tant and mixed with 2.0 ml each of acid reagent and diphenylamine reagent Simultaneously standard and blank were treated in the same way Mix all the tubes, cover with marbles and placed ... Blood and urine samples were kept on ice prior centrifugation All the serum and urine samples were stored at -20°C The lipid profile and sugar was done with automated instrument The HbA1C, CRP and ... nephropathy (160.3 ± 28.0 mmHg) and diabetic Within recent years, there has been considerable interest and research into sialic acid and its use as a potential inflammatory marker for diabetes...
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Báo cáo y học: " The cationic amino acid transporter 2 is induced in inflammatory lung models and regulates lung fibrosis" pps
... 5344352 into pBluescript, linearized by Hind III and Not I digestion, and anti-sense and sense RNA probes, respectively, were generated by T3 and T7 RNA polymerase (Riboprobe Gemini Core System ... participated in the conception and design of the study and helped revise the manuscript; LGE and MGC helped revise the manuscript; NZ participated in the conception, design and coordination of the study, ... Culture Collection, Rockville, MD], was liberated with NdeI and MluI, confirmed by sequencing, radiolabelled with 32P, and hybridized using standard conditions, as described previously [13] Measurement...
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Báo cáo y học: "Apoptosis of resident and inflammatory macrophages before and during the inflammatory response of the virgin bovine mammary gland" docx
... RESMAC and INFMAC before and during the inflammatory response and during in vitro cultivation were tested by determining the proportions of apoptotic and necrotic cells, CD14 + and CD11b + cells, and ... article as: Sladek and Rysanek: Apoptosis of resident and inflammatory macrophages before and during the inflammatory response of the virgin bovine mammary gland Acta Veterinaria Scandinavica 2010 ... monocyte-like and vacuolized INF MAC after PBS (64.4 ± 12.4% and 93.7 ± 1.7%) and after LPS (75.1 ± 13.1% and 99.5 ± 0.5%) Apoptosis and necrosis of resident macrophages from untreated heifer mammary glands...
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Báo cáo y học: "GAS6 in systemic inflammatory diseases: with and without infection" docx
... Plasma concentrations of Gas6 (growth arrest specific protein 6) and its soluble tyrosine kinase receptor sAxl in sepsis and systemic inflammatory response syndromes Crit Care 2010, 14:R158 Linger ... tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer Adv Cancer Res 2008, 100:35-83 Fernandez-Fernandez L, Bellido-Martin L, Garcia de Frutos P: ... genes and carotid atherosclerosis Thromb Haemost 2010, 104:592-598 doi:10.1186/cc9263 Cite this article as: Hurtado B, García de Frutos P: GAS6 in systemic inflammatory diseases: with and without...
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Role of allergy and mucosal inflammation in nasal polyps and chronic sinusitis 3
... correlations between CD56+ NK cells and other inflammatory cells, i.e., CD4+ and CD8+ T cells, eosinophils, neutrophils and mast cells; and of the correlations between NK cells and tIgE or sIgE to common ... 287 polyps and chronic sinusitis Whether allergy plays a cause -and- effect role in the pathogenesis of nasal polyps and chronic sinusitis remains controversial In clinic, the skin prick test and ... Other Inflammatory Cells in the Same Sample Table 49 P values of Mann-Whitney test for the cell number of NK cells and other inflammatory cells (CD4+ and CD8+ T cells, eosinophils, neutrophils and...
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Role of allergy and mucosal inflammation in nasal polyps and chronic sinusitis 2
... sinusitis patients and controls 2.5 Inflammatory Cell Scores in Nasal Polyps and Chronic Sinusitis 2.5.1 Inflammatory Cell Scores in Nasal Polyps and Its Paired Middle Turbinate, and Middle Turbinate ... of inflammatory cells Epithelium shows severe basal cell hyperplasia Glands totally disappear B Nasal polyp tissue with high edema, infiltration of inflammatory cells, disappearance of glands and ... the inflammatory cell studied and its percentage in the study group Eosinophils, CD4+ and CD8+ T cells, and neutrophils were the main inflammatory cells infiltrated in nasal polyp tissue and...
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Role of allergy and mucosal inflammation in nasal polyps and chronic sinusitis
... Pathogenesis of nasal polyps and chronic sinusitis 1.6.1 Pathogenesis of nasal polyps and chronic sinusitis 1.6.2 Inflammatory cell and chemical mediators in nasal polyps and chronic sinusitis ... nasal polyps and chronic sinusitis 2.5.1 Inflammatory cell scores in nasal polyps and its paired middle turbinate, and middle turbinate of allergic rhinitis patients and controls 2.5.2 Inflammatory ... Conferences xxvi Chapter Nasal polyps and chronic sinusitis: state of the art 1.1 Anatomy and physiology of the nose 1.2 Prevalence of nasal polyps and chronic sinusitis 1.2.1 Nasal polyps, a disease with...
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Báo cáo y học: " Inflammatory cytokines, goblet cell hyperplasia and altered lung mechanics in Lgl1+/- mice" pptx
... mouse LR and IM characterized Lgl1 mRNA and protein, elastin and tropoelastin mRNA, and goblet cells and mucin mRNA in Lgl1+/- heterozygotes and wild type controls TB participated in H and E histochemistry ... Health Research (FK and NBS) and graduate scholarships from the Montreal Children's Hospital Research Institute (LR, TB and SC) and from The Respiratory Health Network of the FRSQ and the Canadian ... expression of IL-4 and IL-13 mRNA Postnatal Lgl1+/- mice display increased expression of IL-4 and IL-13 mRNA IL-4 and IL-13 mRNA was quantified in mRNA isolated from total lungs of Lgl1+/+ and Lgl1+/-...
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Báo cáo y học: "ribriform-Morular Variant of Papillary Carcinoma: Association with Familial Adenomatous Polyposis Report of Three Cases and Review of Literature"
... glandular and spindle cell components: A case report Pathol Res Pract, 1996 192(1): 72-74 Hizawa K, et al Association between thyroid cancer of cribriform variant and familial adenomatous polyposis ... thyroglobulin, epithelial membrane antigen, cytokeratin, vimentin, estrogen and progesterone receptors, bcl-2 and Rb proteins Calcitonin and carcinoembryonic antigen were negative Follow-up showed seven ... trabecular and solid patterns There have been several cases showing germline mutations in the APC gene which have also been found in the colonic polyps Hot spots on codons 1061, 1039 and 698 of...
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Báo cáo y học: "Incidence of Ocular Zoonoses referred to the Inflammatory and Autoimmune Ocular Diseases Service of the University of Parma - Italy"
... combination of medical treatment and surgery, with a final visual acuity of 40% in the affected eye [1] The only case of Lyme disease affected a 31 year-old farmer and his ocular manifestations...
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Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc
... of RMI1 and E2Fs in adipocytes, and causes a positive interaction between the molecules Increased expression of RMI1 and E2Fs regulates the cell cycle, leading to adipocyte hyperplasia and subsequent ... of RMI1 and E2Fs thereby regulates the cell cycle, leading to adipocyte hyperplasia and the development of obesity Further studies are clearly needed to explore the detailed mechanism and interaction ... Yoshino, Shun-ichiro Matsumoto, and Masanori Naitou at Astellas Pharma Inc., and Mses Chihiro Yamazaki and Rie Fujikawa at Trans Genic Inc for their helpful advice and support The intake of excess...
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Oncogenesis, Inflammatory and Parasitic Tropical Diseases of the Lung Edited by Jean-Marie Kayembe potx
... Dejan Maglic and Sinan Zhu Chapter Relationship Between Toxicogenomic and Environment and Lung Cancer 61 M Adonis, M Chahuan, A Zambrano, P Avaria, J Díaz, R Miranda, M Campos, H Benítez and L Gil ... other proteins and molecules (Fig 2) Oncogenesis, Inflammatory and Parasitic Tropical Diseases of the Lung Figure The binding of specific ligands to the receptor activates EGFR and generates a ... led to suspend the development of sorafenib in NSCLC 12 Vandetanib Vandetanib is an oral TKI that inhibits VEGFR-2 and -3, RET and EGFR Vandetanib in combination with carboplatin/paclitaxel resulted...
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Báo cáo hóa học: " Detection of epithelial apoptosis in pelvic ileal pouches for ulcerative colitis and familial adenomatous polyposis" pot
... pro -inflammatory cytokines like TNF-a, IL-1b, IL-6, IL-8, IFN-g are elevated in UC patients, but poorly studied in FAP [4,27-30] The inflammatory and apoptosis pathways are linked and some pro -inflammatory ... us to understand more about molecular biology involved in pouchitis, and in the primary diseases, FAP and UC Conclusions In summary, the present study shows that, even under non -inflammatory ... participated in its design and performed the statistical analysis CSRC participated in its design and coordination, and helped to draft the manuscript All authors read and approved the final manuscript...
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báo cáo hóa học: "The psychometric validation of a US English satisfaction measure for patients with benign prostatic hyperplasia and lower urinary tract symptoms" potx
... Health and Quality of Life Outcomes 2009, 7:55 ments of responsiveness in the clinical trial that also used data from baseline and other follow-up visits (visits 2, and 10 – baseline, 13 weeks and ... arms – com- http://www.hqlo.com/content/7/1/55 bination (dutasteride and tamsulosin), dutasteride and placebo, and tamsulosin and placebo Responsiveness Responsiveness is the ability of an instrument ... QoL score and for the low medium and high impact categories on the BII The F statistics for the PPSM Total Score, PPSMGlobal and PPSM-Pain comparisons with the IPSS, IPSS QoL Item and BII were...
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báo cáo hóa học: " Exploring the validity of estimating EQ-5D and SF-6D utility values from the health assessment questionnaire in patients with inflammatory arthritis" potx
... 59 years) and BSRBR (median 59 years) studies, and had lower DAS28 scores (median: BROSG 4.0 vs STIVEA 5.5 and BSRBR 6.0) and lower median tender (median: BROSG vs STIVEA and BSRBR 12) and swollen ... baseline and in terms of the change between baseline and the final follow-up The mean differences between predicted and observed values were calculated and presented with 95% confidence intervals and ... the HAQ, EQ-5D and SF-6D at baseline and for change over time using Spearman’s rank because the HAQ and EQ-5D are non-normally distributed The mean predicted and observed EQ-5D and SF-6D scores...
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