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pmra phop or pmrd deletion on ppmrh lacz or ppmrd lacz activity

Báo cáo khoa học: Selecting cells with different Alzheimer’s disease c-secretase activity using FACS Differential effect of presenilin exon 9 deletion on c- and e-cleavage doc

Báo cáo khoa học: Selecting cells with different Alzheimer’s disease c-secretase activity using FACS Differential effect of presenilin exon 9 deletion on c- and e-cleavage doc

Báo cáo khoa học

... molar concentrations for splice-overlap PCR and cloned into pCDNA3.1+ (Invitrogen) or into pIRESpuro2 (Clontech) to enable the control of gene transcription by adjusting the concentration of puromycin ... difluoroketone inhibitor MW167 [34], at 50 lM concentration (Fig 3D) To confirm that c-secretase inhibition paralleled the loss of fluorescence, the cell media were analyzed for Ab production Each ... MW167 which is consistent with a previous report using a luciferase reporter assay [53] These effective concentrations of both inhibitors on c-secretase activity also correspond to their potency...
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báo cáo hóa học:

báo cáo hóa học: " Effect of substrate (ZnO) morphology on enzyme immobilization and its catalytic activity" pptx

Hóa học - Dầu khí

... science foundation (No 20100470131) Author details National Key Laboratory of Micro/Nano Fabrication Technology, Key Laboratory for Thin Film and Microfabrication of the Ministry of Education, Research ... used for the surface modification determines the uniformity of the coating layer as well as the amount of amino groups The aforementioned procedure was also performed on the surface modifications ... causing less conformation change of HRP on the ZnO surface, leading to a higher catalytic efficiency In brief, the 3D nanomultipod is more appropriate for the immobilization of enzyme and for being...
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Báo cáo hóa học:

Báo cáo hóa học: "Effects of Pin-up Oxygen on [60]Fullerene for Enhanced Antioxidant Activity" pptx

Hóa học - Dầu khí

... chemistry for evaluating antioxidant activity The method is based on the discoloration of the yellowish color of a b-carotene solution due to the breaking of p-conjugation by the addition of lipid ... molar absorption coefficient e = 5.06 104 M-1 cm-1 determined at kmax 329 nm for the cyclohexane solution according to the previously reported method [13b] The concentration and the yield for C60O ... fullerene inclusion complexes were synthesized by modified literature method [12] The formation of c-CD/C60O has been confirmed only by a mass spectrum [15] Thus, we confirmed its formation (obtained...
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Báo cáo y học:

Báo cáo y học: "Effects of altitude on circadian rhythm of adult locomotor activity in Himalayan strains of Drosophila helvetica" docx

Báo cáo khoa học

... for 11 days under controlled laboratory conditions The male of the haH strain had unimodal activity pattern with onset of activity occurring in the subjective forenoon, ~4.5 h after lights -on ... 0.5°C under controlled laboratory conditions Males of the haH strain had a unimodal activity pattern in which activity onset occurred in the subjective forenoon, ~4.5 h after lights -on (A) Males ... the field or lights -on of LD 12:12 cycles in the laboratory to the time of activity onset as given by an eye-fitted line to 11 successive activity onsets The phase of activity termination (Ψe)...
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Báo cáo y học:

Báo cáo y học: "Clinical Symptoms Associated with Asystolic or Bradycardic Responses on Implantable Loop Recorder Monitoring in Patients with Recurrent Syncope"

Y khoa - Dược

... and personal protection against mosquito bites (repellants, window screens, protective clothing,…) Vaccination, a long term solution, is still in the research phase In conclusion, chorioretinal ... al Chorioretinal involvement in patients with West Nile virus infection Ophthalmology 2004;111:2065-70 Garg S, Jampol LM Systemic and intraocular manifestations of West Nile virus infection Surv ... infection associated with neurologic disease The unique pattern of multifocal chorioretinitis can help establish an early diagnosis of the disease while serologic testing is pending Therefore,...
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Báo cáo y học:

Báo cáo y học: "Clinical Symptoms Associated with Asystolic or Bradycardic Responses on Implantable Loop Recorder Monitoring in Patients with Recurrent Syncope"

Y khoa - Dược

... (>10 second pause) or bradycardic (< 20 beats per minute) response corresponding to syncopal event during ILR monitoring Inclusion criterion We queried our data base of implanted loop recorders ... testing on ILR monitoring In group 1, eight patients had bradycardia (HR < 20) for > 10 seconds and three patients had asystole >10 seconds One of the patients had a 44-second sinus pause on ILR monitoring ... without asystolic or bradycardic response on ILR monitoring Symptoms (Table and Figure 1) Aura or prodrome: Only thirteen percent of patients in group1 had aura or warning signs before syncope compared...
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EXESRCISES ON PAST SIMPLE OR PRESENT PERFECT

EXESRCISES ON PAST SIMPLE OR PRESENT PERFECT

Tiếng anh

... signal word for 'Just' is a signal word for '2 years ago' is a signal word for 'Yet' is a signal word for 'Yesterday' is a signal word for Positive Sentences Put the verbs into the correct ... signal word for ' ago' is a signal word for 'Until now' is an signal word for 'Yesterday', 'last week' und 'in 2006' are signal words for 'Just', 'already', 'yet' are signal words for Positive ... two weeks in Brighton with my parents to London one weekend (you / like) it? Oh yes We really (have) a great time in London Lucky you! I (be / never) to London Simple Past or Present Perfect...
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FOCUS ON - phrasal verbs and will or  be going to

FOCUS ON - phrasal verbs and will or be going to

Kỹ năng nói tiếng Anh

... -ing form past tense past participle tell on & tells on telling on told on told on tell on tell on p.v [informal—used primarily by children] When you tell on people, you inform someone in authority, ... invention really works Infinitive present tense -ing form past tense past participle carry on & carries on carrying on carried on carried on carry on carry on p.v When you carry on, you continue ... tense -ing form past tense past participle go for & goes for going for went for gone for go for go for p.v [informal] When you go for something, you like it a lot Erik really goes for scuba diving...
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Tài liệu Tips on Applying for and Passing the PMP or CAPM Exam pptx

Tài liệu Tips on Applying for and Passing the PMP or CAPM Exam pptx

Quản lý dự án

... passing score on the exam Nor is experience alone One of the more often-cited reasons for candidates not to pass the exam on the first try is due to their reliance on experience alone Often, ... Implement approved actions and workarounds • Monitoring and Controlling - Measure project performance - Verify and manage changes - Monitor status of risks - Ensure deliverables conform to quality standards ... application on- line, which is the preferred method, I suggest using the paper form to compile and organize the information beforehand Once it is compiled, actual entry of the information goes...
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TipS on talkS OR how to keep an audience attentive, alert, and around

TipS on talkS OR how to keep an audience attentive, alert, and around

Công nghệ thông tin

... familiarity with the subject, shares one common trait; simplicity The speaker convincingly presented a few conclusions, which I retained for a long time It is more important to get across a few points ... substandard effort Probably every experienced speaker skirts this pitfall and some of us fall into it Over-confidence is a common reason, but a poor excuse for inadequate preparation Preparation consists ... key words and phrases; valuable because it offers a means of checking content and organization before a group of friends prior to the presentation It is necessary because it is almost the only...
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Financial distress prediction based on OR-CBR in the principleof k-nearest neighbors

Financial distress prediction based on OR-CBR in the principleof k-nearest neighbors

Kỹ thuật lập trình

... (2005) An application of pattern recognition on scoring Chinese corporations financial conditions based on back propagation neural network Computers & Operations Research, 32(5), 1115–1129 Liao, S.-H ... mechanism of OR- CBR and other feature-weighted ones correlation measure is employed to transform memberships of target case and stored cases on each feature to grey correlation matrix Based on the ... relations between target case and stored cases Get_outranking_relations(c0, ci, q, p, v); //Computing concordance and discordance indices on each feature Get_concordance(c0, ci); Get_discordance(c0,...
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Tài liệu Báo cáo khóa học: Further insights into the assembly of the yeast cytochrome bc1 complex based on analysis of single and double deletion mutants lacking supernumerary subunits and cytochrome b pdf

Tài liệu Báo cáo khóa học: Further insights into the assembly of the yeast cytochrome bc1 complex based on analysis of single and double deletion mutants lacking supernumerary subunits and cytochrome b pdf

Báo cáo khoa học

... subunit and subunit Deletion of the gene for any one of these proteins caused a strong decrease or the disappearance of the other two components Accordingly, the double deletion mutant VZ6, in ... and a strong decrease of subunit and both core proteins Accordingly, the QCR8 gene deletion resulted in the most severe phenotype among the single deletion strains tested In the deletion mutant ... the corresponding quantifications are reported in Table A comparison of the immunoblots in Figs and reveals that the double deletions of genes encoding bc1 subunits had more marked effects on the...
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Tài liệu Báo cáo khoa học: Effect of deletion of the DNase I hypersensitive sites on the transcription of chicken Ig-b gene and on the maintenance of active chromatin state in the Ig-b locus docx

Tài liệu Báo cáo khoa học: Effect of deletion of the DNase I hypersensitive sites on the transcription of chicken Ig-b gene and on the maintenance of active chromatin state in the Ig-b locus docx

Báo cáo khoa học

... intergenic regions by solid lines Horizontal arrows represent transcriptional orientations Exon numbers are indicated The hypothesized organization of a portion of the Na channel gene for which the ... carried out by the introduction of the region IV deletion construct into 16 kb Del cells Genomic Southern hybridization was performed to confirm deletions (Fig 3) For region I (Fig 3A), genomic DNA ... groups based on location For each group, a deletion construct was introduced into DT40 cells Ig-b gene expression, acetylation of H3 and H4 FEBS Journal 272 (2005) 422–432 ª 2004 FEBS Deletion of hypersensitive...
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PHYSICS AND POLITICS OR THOUGHTS ON THE APPLICATION OF THE PRINCIPLES OF ''''NATURAL SELECTION'''' AND ''''INHERITANCE'''' TO POLITICAL SOCIETY pptx

PHYSICS AND POLITICS OR THOUGHTS ON THE APPLICATION OF THE PRINCIPLES OF ''''NATURAL SELECTION'''' AND ''''INHERITANCE'''' TO POLITICAL SOCIETY pptx

Cao đẳng - Đại học

... action may require all our attention and all our volition for its first, or second, or third performance, but by frequent repetition it becomes, in a manner, part our organisation, and is performed ... time, for example, or of Queen Elizabeth's time, or George II.'s time; or again of the age of Louis XIV., or Louis XV., or the French Revolution; an idea more or less accurate in proportion as ... nation tried constantly to be the stronger, and so made or copied the best weapons; by conscious and unconscious imitation each nation formed a type of character suitable to war and conquest Conquest...
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Báo cáo khoa học:

Báo cáo khoa học: "Insertion, Deletion, or Substitution? Normalizing Text Messages without Pre-categorization nor Supervision" docx

Báo cáo khoa học

... using sentences by incorporating context word information, and consider many-to-one letter transformation in the model 5 Acknowledgments The authors thank Deana Pennell for sharing the look-up ... first one is a comprehensive list of chat slangs, abbreviations, and acronyms collected by InternetSlang.com; it contains normalized word forms for 6,105 commonly used slangs The second is the word-abbreviation ... Edinburgh corpus For both the deletion and letter transformation lookup tables, we generate a ranked list of candidate words for each nonstandard token, by sorting the combined score p(Ti |Si )...
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Báo cáo Y học: Membrane embedded location of Na+ or H+ binding sites on the rotor ring of F1F0 ATP synthases ppt

Báo cáo Y học: Membrane embedded location of Na+ or H+ binding sites on the rotor ring of F1F0 ATP synthases ppt

Báo cáo khoa học

... removal of unbound uorescent probe Determination of binding site accessibility for Na+ in reconstituted c11 oligomer The same reconstitution procedure was used For better incorporation yields, soy ... reconstituted into vesicles containing lipids harboring a spin label at different positions on the fatty acid chain The uorescence yields depend on the spinlabel position and the concentration ... titration of uorescence yield with dierent quencher concentrations, samples were incubated with a specic quencher for from a M stock solution prior to recording spectra Emission spectra were recorded...
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Bonds or Loans? On the Choice of International Debt Instrument by Emerging Market Borrowers pdf

Bonds or Loans? On the Choice of International Debt Instrument by Emerging Market Borrowers pdf

Ngân hàng - Tín dụng

... they are monitored Choice by the lenders whether or not to monitor For lenders to be willing to monitor, it is necessary that monitoring is needed (condition (5) is violated).17 Monitoring will ... cancellation, a borrower’s reputation worsens within the bank syndicate but not beyond, whereas in case of default a borrower’s reputation worsens everywhere A noreputation cost interpretation is ... threat to a borrower and therefore makes monitoring efficient In contrast, after the launch of an international bond, bondholders have little control over the issuer’s actions, since a bond issue...
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Trick or Treatment?: Alternative Medicine on Trial pot

Trick or Treatment?: Alternative Medicine on Trial pot

Sức khỏe giới tính

... body contains only litres of b l o o d , so a significant fraction was being bled from Washington at each session Dr Craik did not seem concerned He performed venesection again in the afternoon, ... o oranges and a lemon each day A n o t h e r g r o u p of sick sailors w h o continued with the normal naval diet w e r e also monitored and acted as a control g r o u p There are t w o important ... is focused on one treatment for one ailment H o w e v e r , the trial took place while Hamilton was serving in the Peninsular War in Portugal, where battlefield conditions did not afford him the...
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Effects of longterm ingestion of cd polluted rice or low dose cd supplemented diet on the endogenous cop

Effects of longterm ingestion of cd polluted rice or low dose cd supplemented diet on the endogenous cop

Môi trường

... Cadmium, World Heath Organisation, Geneva 2) WHO (1992b) Environmental Health Criteria 135 Cadmium-Environmental Aspect, World Heath Organisation, Geneva 3) Friberg, L., Piscator, M., Nordberg, ... shown), a significant correlation coefficient was observed between Cd and Zn after 18 months, except for groups II and VI at 18 months, and groups II and III at 22 months Concentration of Cd, Cu, and ... Pearson’s Correlation Coefficients between Cd and Zn Concentrations in the Liver of Rats Fed CdPolluted rice or Cd-Supplemented Diet for 12, 18, and 22 months I II III IV V VI 12 months −0.0189...
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