ploidy genome instability and cancer
Báo cáo y học: "Morphological instability and cancer invasion: a ''''splashing water drop'''' analogy" potx
Ngày tải lên :
13/08/2014, 16:21
... fate determination and phenotype Cancer Res 2006, 66:7833-7836 Cristini V, Frieboes HB, Gatenby R, Caserta S, Ferrari M, Sinek J: Morphologic instability and cancer invasion Clin Cancer Res 2005, ... proliferative, and enzymatic characterizations J Neurosurg 1997, 87:602-609 Vander Wal RL, Berger GM, Mozes SD: The combined influence of a rough surface and thin fluid film upon the splashing threshold and ... Suppression of prostate cancer invasive potential and matrix metalloproteinase activity by E-cadherin transfection Cancer Res 1999, 59:3552-3665 Margulis A, Zhang W, Alt-Holland A, Crawford HC, Fusenig...
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NBS1 deficiency promotes genome instability by affecting DNA damage signaling pathway and impairing telomere integrity
Ngày tải lên :
12/10/2015, 17:35
... lab two and a half years ago, which I feel extremely lucky and fortunate Dr Wang’s enthusiasm to research and science infects me and motivates me all the time Her encouragement, patience and advices ... 1.5.1 Telomere and telomerase 22 1.5.2 Telomere and shelterin complex 24 1.5.3 Other telomere associated proteins 28 1.5.4 Telomerase and shelterin in cancer and aging ... ATM- and ATR-mediated signaling pathways are highly interconnected ATM and ATR communicate with each other to coordinate and modulate the cellular outputs in respond to DNA strand breaks and stalled...
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NBS1 deficiency promotes genome instability by affecting DNA damage signaling pathway and impairing telomere integrity
Ngày tải lên :
26/11/2015, 22:49
... lab two and a half years ago, which I feel extremely lucky and fortunate Dr Wang’s enthusiasm to research and science infects me and motivates me all the time Her encouragement, patience and advices ... 1.5.1 Telomere and telomerase 22 1.5.2 Telomere and shelterin complex 24 1.5.3 Other telomere associated proteins 28 1.5.4 Telomerase and shelterin in cancer and aging ... ATM- and ATR-mediated signaling pathways are highly interconnected ATM and ATR communicate with each other to coordinate and modulate the cellular outputs in respond to DNA strand breaks and stalled...
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Báo cáo y học: "Application of Small Angle X-ray Scattering (SAXS) for Differentiation between Normal and Cancerous Breast Tissue"
Ngày tải lên :
02/11/2012, 11:08
... are 0.33, 0.36, 0.46 and 0.4 nm for carcinoma, fibrocystic changes, adipose and fibroglandular tissues respectively Comparison of the measured signatures between the fresh and frozen tissues is ... materials and body tissues Med Phys 1987; 14 (4): 1811-1816 Lewis RA, Rogers KD, Hall CJ, Towns-Andrews E, Slawson S, Evan A, Pinder SE, Ellis IO, Boggis CRM, Hufton AP and Dance DR Breast cancer ... between normal and tumor breast tissues Furthermore, it is possible to differentiate between fibrocystic changes and carcinoma using this parameter The difference between adipose and tumors is...
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Modeling Cell Cycle Control and Cancer with pRB Tumor Suppressor
Ngày tải lên :
25/10/2013, 21:20
... frequent types of cancer diagnosed in the United States in decreasing incidence are breast cancer, prostate cancer, lung cancer and colon cancer; yet lung cancer is the deadliest form of cancer in the ... Cdc28 and classes of vertebrate cyclins (D- and E-type cyclins in G1 and A -and B-type cyclins in G2/M) that control a family of Cdks (cyclindependent kinases) greatly enhanced our understanding ... 1997; Zachariae and Nasmyth 1999) These studies and others demonstrated the universality of the cell Modeling Cell Cycle Control and Cancer with pRB Tumor Suppressor 231 cycle, and strongly suggested...
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Tài liệu The Early Detection Research Network: Investing in Translational Research on Biomarkers of Early Cancer and Cancer Risk docx
Ngày tải lên :
14/02/2014, 21:20
... cancers, gastrointestinal and other associated cancers, lung and upper aerodigestive cancers and prostate and urologic cancers, each have biomarkers in prevalidation and validation phases in which ... Texas M D Anderson Cancer Center Colorectal and Other Gastrointestinal Cancers 35 Colorectal Cancer Colon cancer is the third most frequently diagnosed cancer in the United States and the third ... sequences and other biomarkers have been identified as promising biomarkers for bladder and prostate cancers; and mutations and deletions in mitochondrial DNA were detected in prostate and other cancers...
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Tài liệu Pesticide Residues in Food and Cancer Risk: A Critical Analysis pdf
Ngày tải lên :
14/02/2014, 22:20
... bioassays and are carcinogenic (Gold et al., 1997b) Dehydroepiandrosterone (DHEA) and DHEA sulfate are the major secretion products of adrenal glands in humans and are precursors of androgenic and ... Stofberg and Grundschober (1987) 800 Stofberg and Grundschober (1987), Lorenz and Maga (1972) Stofberg and Grundschober (1987), Arkima (1968) (7300) TAS (1989), Nelson and Hoff (1969), Kazeniac and ... Stofberg and Grundschober (1987), Blauch and Tarka (1983), Nagata and Sakai (1985), IARC (1991) EPA (1989a), Risch and Herrmann (1988) TAS (1989), Eltayeb and Roddick (1984) 4100 Stofberg and Grundschober...
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Tài liệu The Diet and Cancer Connection ppt
Ngày tải lên :
15/02/2014, 04:20
... with cancer of the mouth, larynx, pharynx and esophagus, and heavy beer drinking is associated with cancer of the rectum Cancer can develop anywhere along the gastrointestinal tract, but colon cancer ... Nutrition and Health, stomach cancer has been found among populations who eat lots of pickled vegetables (Japan), salted fish (Norway) and smoked trout and mutton (Ireland) Esophageal cancer is ... certain types of cancer, especially if you drink and smoke Choose high-fiber foods Besides fresh fruits and vegetables, add more whole grain breads and cereals and legumes (dried peas and beans) to...
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Tài liệu Changing patterns of cardiovascular diseases and cancer mortality in Portugal, 1980--2010 docx
Ngày tải lên :
15/02/2014, 04:20
... mortality and YLL, and the transition towards cancer In more recent years, the highest burdens of disease came from cancers in men and from cardiovascular diseases in women Keywords Cancer, Cardiovascular ... rates and numbers of deaths were performed for all ages and by age groups (0–14, 15–34, 35–54, 55–74 and ≥75 years) The YLL due to premature mortality for each cause (CVD and cancer) , gender and ... 1980 and 2010, the burden of CVD was much higher compared to cancer and, in 2010, CVD were responsible for 10,000 deaths more than cancers Among men, the YLL from cancer increased between 1980 and...
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Tài liệu What Lung Cancer Patients Need to Know About Bone Health: A Publication of The Bone and Cancer Foundation pdf
Ngày tải lên :
15/02/2014, 05:20
... (noncancerous) or malignant (cancerous) Vertebra: The bony segments that make up the spinal column The mission of The Bone and Cancer Foundation is to: • Provide information to cancer patients and ... information can be found in the Bone and Cancer Foundation publication “Osteonecrosis of the Jaw – Information for Cancer Patients” available online at www.boneandcancerfoundation.org or by calling ... percent of people with lung cancer will have their cancer spread, or metastasize, to bone When lung cancer metastasizes, tumor cells from the original cancer break off and travel through the blood...
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Tài liệu Trans Care Medical issues: Trans people and cancer ppt
Ngày tải lên :
15/02/2014, 05:20
... for skin cancer, colon cancer, and lung cancer is the same for women and men (trans or not) Trans people should have the same screening as anyone else for these kinds of cancers Some cancer protocols ... detection and treatment of cancer The rest of this booklet focuses on trans-specific protocols for cancer screening Trans-Specific Cancer Screening Recommendations The earlier cancer is detected and ... spread Cancer of the uterus” usually refers to cancer of the lining of the uterus (endometrium) Endometrial cancer is the fourth most common type of cancer in BC and is the most common cancer...
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Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer ppt
Ngày tải lên :
16/02/2014, 09:20
... to ERBB3 and ERBB4 NRG1 and NRG2 bind to both ERBB3 and ERBB4, whereas NRG3 and NRG4 only bind to ERBB4 [3] Although these ligands show redundancy, heparinbinding-EGF is the only ligand whose ... 3-kinase, and thus is a preferred dimerization partner EGFR and cancer EGFR overexpression and cancer EGFR is expressed in a variety of human tumors, including those in the lung, head and neck, ... relatively low, being 33, 24 and 28%, respectively regulin and epigen); (b) those that bind to EGFR and ERBB4 (including betacellulin, heparin-binding EGF and epiregulin); and (c) neuregulin (NRG)...
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Tài liệu Báo cáo khoa học: Comparison of membrane fraction proteomic profiles of normal and cancerous human colorectal tissues with gel-assisted digestion and iTRAQ labeling mass spectrometry pptx
Ngày tải lên :
16/02/2014, 15:20
... because of their low concentration and high hydrophobicity New tools and strategies are needed so that membrane fractions from cancer cells can be screened for candidate biomarkers In this study, ... Overexpression of CLDN3, HLA-A1, TAPBP and SLC25A4 in colorectal cancer has not been prominently reported, and there is interest in developing these proteins as diagnostic and prognostic markers for this ... in epithelial and endothelial cells [22] Specifically, CLDN1, -3, -4, -5, -7, -10 and -16 have been found to be altered in various cancers [23] Overexpression of these proteins in cancer is unexpected,...
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Tài liệu Pathophysiology and Clinical Aspects of Venous Thromboembolism in Neonates, Renal Disease and Cancer Patients Edited by Mohammed A. Abdelaal ppt
Ngày tải lên :
19/02/2014, 23:20
... groups and demonstrated the important differences between VTE in adults and pediatric patients and called for evidencebased guidelines for management and prevention of VTE in neonates and children ... patient lives” and issued a call for action stating that DVT and PE constitute major health problem in the USA and more people die of PE than motor vehicle accidents, breast cancer or AIDS, and physicians, ... Pselectin and thrombospondin all of which help promote thrombosis (Jy, et al 2007) 3.1.3 Microparticles, VTE and cancer In contrast to the above discussion for idiopathic VTE – thrombosis, cancer and...
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Tài liệu Báo cáo khoa học: Medium-chain dehydrogenases/reductases (MDR) Family characterizations including genome comparisons and active site modelling pdf
Ngày tải lên :
21/02/2014, 03:20
... the human and A thaliana sequences are presently lacking Furthermore, COG groups the YADH and CAD families together in COG 1064, and the MRF and QOR families together in COG 0604 COG and PFAM ... contribute zinc ligands [43] The exact nature of one ligand has been much investigated previously [44] In DM_7300579, two of the zinc ligands, Glu156 and Cys45, are missing and we postulate that ... the PDHs and QORs Finally, there are the two families of ACRs and LTDs, and a few forms that not belong to any of the families mentioned Half of the families are zinc-containing MDRs and half...
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Innate Immune Regulation and Cancer Immunotherapy pot
Ngày tải lên :
05/03/2014, 23:20
... Double-Stranded RNA and Activation of Innate Immunity by RIG-I-Like Receptors Mitsutoshi Yoneyama and Takashi Fujita 51 Innate Immune Signaling and Negative Regulators in Cancer Helen Y Wang and ... of cancer Parts of the Book Part I of the book discusses innate immune signaling and inflammatory responses to pathogens and cancer Chapters and introduce innate lymphocytes, including NKT and ... cells and their roles in innate immune response to cancer Chapters and offer an overview of TLR- and RLR-mediated innate immune signaling and their role in detecting invading pathogens and initiating...
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Imaging and cancer: A review docx
Ngày tải lên :
06/03/2014, 00:22
... example PET and MR and ultrasound and MR, there will be a need to have standardization in order to follow longitudinal studies of response to therapy Cancer is a multi-factorial disease and imaging ... detection of small cancers and depicts significantly more cancers and at smaller size and lower stage than does a physical examination, which detects independently extremely few cancers Mammographic ... head and neck cancer and non-small cell lung cancer (Eschmann et al., 2005) Slow specific accumulation and clearance from normoxic tissues will limit the clinical use of 18F-MISO 18F-FAZA and 18...
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CHILDREN AND CANCER-Children''''s Health and the Environment pdf
Ngày tải lên :
06/03/2014, 01:20
... Children and Cancer CHILDHOOD CANCER OBJECTIVES To discuss childhood cancer To address the links between childhood environments and adult onset of cancer To present current knowledge of causation and ... To discuss cancer clusters To present educational and preventive measures Children and Cancer OVERVIEW INCIDENCE AND TYPES OF CHILDHOOD CANCER CAUSES, RISK FACTORS AND HYPOTHESES ... DC Children and Cancer OVERVIEW INCIDENCE AND TYPES OF CHILDHOOD CANCER CAUSES, RISK FACTORS AND HYPOTHESES BIOLOGICAL PROCESSES LEADING TO CANCER DEVELOPMENT EXPOSURE ASSESSMENT AND ITS CHALLENGES...
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Nutrition and cancer: A review of the evidence for an anti-cancer diet pptx
Ngày tải lên :
06/03/2014, 02:21
... carotene and vitamin A on lung cancer and cardiovascular disease N Engl J Med 1996, 334:1150-1155 143 The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers ... a high fruit and vegetable diet would reduce cancers of the mouth and pharynx, esophagus, lung, stomach, and colon and rectum; evidence of probable risk reduction was found for cancers of the ... prostate cancer [136], ovarian cancer [137], and breast cancer [138] Recently Grant found that sunlight was also protective for bladder, endometrial, renal cancer, multiple myeloma, and Non-Hodgkins...
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Traditional, Complementary and Alternative Medicine and Cancer Care pptx
Ngày tải lên :
06/03/2014, 09:20
... systems can ‘cure’ cancer The context in international perspective 19 Health policy and CAM in cancer care: UK and Australia The high demand for CAMs amongst UK cancer patients, and recent political ... morbidity from cancer, there is evidence to suggest that, for many cancers, survival rates are lower in the UK (see Department of Health 2000) For cancers like breast cancer and bowel cancer, this ... perspective most common cancers in Australia (excluding non-melanoma skin cancer) are colorectal (bowel), breast, prostate, melanoma and lung cancer (The Cancer Council Australia 2006) Cancer costs AUS$2.7...
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