picture two equally important halves of a whole emerge—a yin and yang of complementary economic
Báo cáo khoa học: The Yin and Yang of protein folding doc
Ngày tải lên :
23/03/2014, 11:20
... age-related amyloidosis, this may lead to the accumulation of large quantities of partially folded proteins and the saturation of the capacity of the quality control machinery, exacerbating the formation ... for dynamical events, of which transient partial unfolding is a natural part Native proteins thus are only marginally stable relative to the denatured state, and partially folded states can be ... structural molecular mechanism of amyloid formation, simultaneously unraveling the cause of debilitating human disease An advanced knowledge about toxic states populated on the aggregation pathway may...
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Báo cáo khoa học: Active-site-specific chaperone therapy for Fabry disease Yin and Yang of enzyme inhibitors pptx
Ngày tải lên :
30/03/2014, 03:20
... disease: an asymptomatic hemizygote with significant residual a- galactosidase A activity Am J Hum Genet 33, 7 1A Nakao S, Takenaka T, Maeda M, Kodama C, Tanaka A, Tahara M, Yoshida A, Kuriyama M, Hayashibe ... Sakuraba H et al (1995) An atypical variant of Fabry’s disease in men with left ventricular hypertrophy N Engl J Med 333, 288–293 Nakao S, Kodama C, Takenaka T, Tanaka A, Yasumoto Y, Yoshida A, ... strands in the (b ⁄ a) 8 barrel, whereas domain contains antiparallel b strands The galactose ligand is shown in yellow and red (B) Fabry disease-causing point mutations are shown on the human a- Gal...
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Báo cáo y học: " The yin and yang of chromatin spatial organization" ppt
Ngày tải lên :
09/08/2014, 20:21
... Starck J, Sarkar R, Romana M, Bhargava A, Scarpa AL, Tanaka M, Chamberlain JW, Weissman SM, Forget BG: Developmental regulation of human gammaglobin and beta-globin genes in the absence of the locus-control ... the Laboratory of Chromatin and Gene Expression for their help and advice, and also thank Lyubomira Chakalova, Claire Joyce and Nicole Shoaf for critical reading of the manuscript This work was ... this article and many more, are likely be important in dynamically shaping the spatial environment and organization of the genome equal but then may become specialized, perhaps transiently by character...
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Báo cáo y học: "The Yin and Yang actions of North American ginseng root in modulating the immune function of macrophages" ppsx
Ngày tải lên :
13/08/2014, 14:20
... performed at least three separate times All statistical analyses were performed with GraphPad prism 4. 0a Software (GraphPad Software Inc., USA) Data were presented as the mean ± standard deviation ... whereas the AQ extract, which contained PS, was immuno-stimulatory These extractrelated anti-inflammatory and pro-inflammatory effects may be considered as the Yin and Yang actions of ginseng Abbreviations ... Pharmacogenomics and the Yin/ Yang actions of ginseng: antitumor, angiomodulating and steroid-like activities of ginsenosides Chin Med 2007, 2:1-21 Iishi H, Tatsuta M, Baba M, Uehara H, Nakaizumi...
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Tài liệu Báo cáo khoa học: Involvement of two positively charged residues of Chlamydomonas reinhardtii glyceraldehyde-3-phosphate dehydrogenase in the assembly process of a bi-enzyme complex involved in CO2 assimilation doc
Ngày tải lên :
19/02/2014, 16:20
... PsativumA SoleraceaA 197 Chlamy 200 Synechocystis 198 Synechococcus 199 R R R R R R R R R R R R R R R R R R R R A A A A A A A A A A R R R R R R R R R R A A A A A A A A A A A A A A A A A A A A A ... T T T T T G G G G G G G G G G A A A A A A A A A A A A A A A A A A A A K K K K K K K K K K A A A A A A A A A A V V V V V V V V V V S S S S A A A S A A L L L L L L L L L L V V V V V V V V V V L ... resonance with GAPDH as analyte and CP12 as ligand (immobilized protein) The free energies of the association of GAPDH and CP12 were calculated according to equations and in the main text Analyte...
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Skills-based health education including life skills: An important component of a Child-Friendly/Health-Promoting School potx
Ngày tải lên :
14/03/2014, 20:20
... Strickland and Joan Woods, USAID, Washington, DC, USA V Chandra-Mouli, Child and Adolescent Health, WHO/HQ, Geneva, Switzerland Charles Gollmar, CDC, Atlanta, GA, USA Delia Barcelona, UNFPA/Headquarters, ... education and services; to the highest attainable standard of physical and mental health; and to formal and non-formal education about population and health issues, including sexual and reproductive ... rates; and available methods of contraception - analyse a variety of potential situations for sexual interaction and determine a variety of actions they may take and the consequences of such actions...
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Báo cáo khoa học: Apolipoproteins A-I and A-II are potentially important effectors of innate immunity in the teleost fish Cyprinus carpio pot
Ngày tải lên :
16/03/2014, 18:20
... as in (A) (E) Western blot analysis of the gel in (D) using a specific anti-apoA-II serum Fig 4B, the intact apoA-I (band a) , an intermediary fragment (band b) and a more stable third band (band ... purified apoA-II also displayed bacteriostatic activity against the Gram-positive and -negative bacteria at micromolar concentrations (Table 1) These results clearly show that although apoA-I seems ... primary structure of apoA-I is poorly conserved among different species, the overall secondary and tertiary structure of HDL-associated apoA-I is remarkably similar, displaying an arrangement of...
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Báo cáo hóa học: " Closing two doors of viral entry: Intramolecular combination of a coreceptor- and fusion inhibitor of HIV-1" docx
Ngày tải lên :
20/06/2014, 01:20
... coefficient calculated on the basis of the amino acid sequence The purity and the proper tetramer formation of mAbs and mAb-FIs were analyzed by SDS-PAGE in the presence and absence of a reducing agent ... that the variable region of the CCR5mAb in BFFI contributes to the antiviral activity Figure Design and biochemical characterization of BFFI Design and biochemical characterization of BFFI A ... NNTTWEAWDRAIAEYAARIEALIRAAQEQQEKNEAALREL B performed BFFI and CCR5mAb had very similar binding affinity to human CCR5, suggesting that addition of the FI did not alter the binding affinity of the...
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báo cáo hóa học: " Elementary proofs of two theorems involving arguments of eigenvalues of a product of two unitary matrices" potx
Ngày tải lên :
21/06/2014, 02:20
... obtain ∗ - ∗ By taking the arguments in Chau and Lam Journal of Inequalities and Applications 2011, 2011:18 http://www.journalofinequalitiesandapplications.com/content/2011/1/18 ↓ ↓ Page of ... Chau and Lam Journal of Inequalities and Applications 2011, 2011:18 http://www.journalofinequalitiesandapplications.com/content/2011/1/18 Page of and ↑ ↑ ↑ θ1 (UV) ≥ θ1 (U) ... equality if and only if θ1 (U) = |θ |↓ (U) and θ1 (V) = |θ |↓ (V) By the 1 Chau and Lam Journal of Inequalities and Applications 2011, 2011:18 http://www.journalofinequalitiesandapplications.com/content/2011/1/18...
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báo cáo hóa học:" Research Article Two New Iterative Methods for a Countable Family of Nonexpansive Mappings in Hilbert Spaces" pdf
Ngày tải lên :
21/06/2014, 11:20
... 2005 15 L S Liu, “Ishikawa and Mann iterative process with errors for nonlinear strongly accretive mappings in Banach spaces,” Journal of Mathematical Analysis and Applications, vol 194, no 1, ... fixed points of nonlinear mappings is an important and active research area In particular, iterative algorithms for finding fixed points of nonexpansive mappings have received vast investigation cf ... “Iterative algorithms for nonlinear operators,” Journal of the London Mathematical Society, vol 66, no 1, pp 240–256, 2002 17 K Aoyama, Y Kimura, W Takahashi, and M Toyoda, “Approximation of common...
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Báo cáo toán học: " Efficiency of Embedded Explicit Pseudo Two-Step RKN Methods on a Shared Memory Parallel Computer" ppsx
Ngày tải lên :
06/08/2014, 05:20
... -evaluations of s components of the big vector F(tn e + hn c, Yn ) over a number of available processors An additional computational effort consists of a recomputation of the variable parameter matrix ... efficient than the codes DOPRI5 and DOP853 for solving expensive nonstiff first-order problems on a shared memory parallel computer We have also obtained a similar performance of a parallel implementation ... Numerical Comparisons The numerical comparisons in this section are mainly made in terms of computing time for an accuracy received However, since the parameters of the two N H Cong, H Podhaisky, and...
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Báo cáo toán học: "A two-dimensional pictorial presentation of Berele’s insertion algorithm for symplectic tableaux" doc
Ngày tải lên :
07/08/2014, 08:22
... n] of length f The R-S correspondence for multiset permutations takes w to a pair (P, Q) where P is a semistandard tableau of the same weight as w, and Q is a standard tableau of the same shape ... is about to reach row r in both the standardized and ˜ unstandardized cases Suppose the intermediate tableau T of the standard case at this point is obtained from the intermediate tableau T of ... we call the symbol λ/µ a skew partition and the set Dλ \ Dµ the diagram of λ/µ The diagram of a skew partition is also called a skew (Young) diagram A skew Young diagram is called a horizontal...
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Báo cáo toán học: "The number of 0-1-2 increasing trees as two different evaluations of the Tutte polynomial of a complete graph" potx
Ngày tải lên :
07/08/2014, 15:22
... Combinatorial Theory Ser A, 18, 141–148, 1975 [4] Foata, D.: Groupes de r´arrangements et nombres d’Euler C R Acad Sci Paris e Sr A- B, 275, A1 147 A1 150, 1972 [5] Foata, D and Strehl, V.: Rearrangements ... Chip-firing and the Tutte polynomial Annals of Combinatorics, 1, 253– 259, 1997 [9] Plautz J and Calderer, R.: G-parking functions and the Tutte polynomial Preprint [10] Stanley, R P.: Hyperplane arrangements, ... arrangements, parking functions and tree inversions In: Sagan, B and Stanley, R (eds) Mathematical Essays in Honor of Gian-Carlo Rota Birkh¨user, Boston, Basel, 359–375, 1998 a [11] D J A Welsh, Counting...
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Báo cáo khoa học: "Hepatic splenosis mimicking HCC in a patient with hepatitis C liver cirrhosis and mildly raised alpha feto protein; the important role of explorative laparoscopy" potx
Ngày tải lên :
09/08/2014, 04:20
... malignancy This had a significant impact of clinical plans and patients management It is already recognized that laparoscopy provides a port of minimally invasive entry for the visualisation of ... hypervascuArterial (A) segment venous phase Arterial (A) and portal venous phase (B) of IV Gadlinium enhanced axial MRI images demonstrating a solitary cm hypervascular nodule in segment VII (Arrow) A ... of segment and (figure 1) There was an increased enhancement in the venous phase scans, and the picture was very suspicious for a focal hepatoma A double contrast MR study, using Gadolinium and...
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Báo cáo y học: ":Evaluation of the Patient Acceptable Symptom State in a pooled analysis of two multicentre, randomised, double-blind, placebo-controlled studies evaluating lumiracoxib and celecoxib in patients with osteoarthritis" pptx
Ngày tải lên :
09/08/2014, 10:20
... disease activity, and functional impairment We present data on patient satisfaction according to PASS during and at the end of the study period and on patient achievement of sustained satisfaction ... variables – OA pain, patient's global assessment of disease activity, and WOMAC™ LK 3.1 Function – was originally estimated using the least square means obtained from an analysis of covariance ... global assessment of disease activity (Table 3; Figure 3a) , and WOMAC™ Function subscale score at week 13 (Table 4; Figure 4a) For each variable (OA pain, patient's global assessment of disease activity,...
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Báo cáo y học: " Coexistence of a colon carcinoma with two distinct renal cell carcinomas: a case report" pps
Ngày tải lên :
11/08/2014, 00:23
... Renal cell carcinoma Esophageal carcinoma Kobayashi et al [6] Papillary renal carcinoma Heart liposarcoma Gałazka et al [7] Renal oncocytoma Endometrioid ovarian and endometrial carcinoma Bezircioğlu ... cancer Indian J Gastroenterol 2000, 19:35-36 19 Adachi Y, Takamatsu H, Noguchi H, Tahara H, Fukushige T, Takasaki T, Yoshida A, Kamenosono A, Kikuchi J, Asatani M, Kawakami K: A malignant rhabdoid ... Brain tumor Adachi et al [19] Renal cell carcinoma Uterine cervical adenocarcinoma Yokoyama et al [20] Cystic renal cell and squamous cell carcinoma Transitional cell carcinoma of ipsilateral...
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Báo cáo y học: "Intussusception of the small bowel secondary to malignant metastases in two 80-year-old people: a case series" potx
Ngày tải lên :
11/08/2014, 00:23
... up and drug administration (letrozole and zoledronic acid) Second case An 80-year-old Caucasian man was admitted to an internal medicine department at our hospital complaining of acute abdominal ... two years ago, with a histologic diagnosis of melanoma Plain abdominal radiographs showed no air-fluid levels and an abdominal CT scan showed bowel obstruction with dilatation of his stomach and ... of Surgical Intervention in the Management of Intestinal Metastases From Malignant Melanoma Am J Surg 1991, 62:428-431 11 Yokota T, Kunii Y, Kagami M, Takahashi M, Kikuchi S, Nakamura M, Yamauchi...
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Báo cáo y học: "Neurocysticercosis as an important differential of seizures in pregnancy: two case reports" pdf
Ngày tải lên :
11/08/2014, 00:23
... Institute of Medical Sciences, Rohtak (124001), Haryana, India Department of Anesthesiology, Pandit Bhagwat Dayal Sharma, Post Graduate Institute of Medical Sciences, Rohtak (124001), Haryana, India Authors’ ... images A copy of the written consent is available for review by the Editor-in-Chief of this journal Author details Department of Obstetrics and Gynecology, Pandit Bhagwat Dayal Sharma, Post Graduate ... brain (Figure 1) A diagnosis of neurocysticercosis was made on the basis of the MRI, convulsion and living in an endemic area She was put on carbamazepine and discharged from the hospital after...
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