physiological basis for differential autonomic regulation
Breathlessness A Physiological Basis For Discussion
... spectrum of perceptive ability in a normal population for most modalities Inappropriate implies a bank of experience in which “appropriate” information is stored “We get used to things” “inappropriate”, ... work” Four key words Recognition Inappropriate Respiratory work Total body work Recognition Some form of detector mechanism within the respiratory system which rises to a conscious level Perception-some ... lungs Higher centres (limbic system) Narrow airways Chest wall Load Drive Diaphragm Work Threshold for work perception range in normals modified by time drug modification Mechanoreceptors Irritant...
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Báo cáo y học: "Differential expression, function and response to inflammatory stimuli of 11β-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation" pps
... were labelled with VIC Reactions occurred as follows: 50°C for minutes, 95°C for 10 minutes, 44 cycles of 95°C for 15 seconds and 60°C for minutes Data were obtained as Ct values (the cycle number ... iU), or IL-4 (10 ng/ml) for 24 hours Total RNA from these cells was then used to assess expression of mRNA for 11βHSD1 In each case mRNA levels for 11β-HSD1 were normalized for the housekeeping ... glycyrrhetinic acid (+ G; µmol/l) for 24 hours Cells were then assessed expression of IL-6 mRNA and protein (a) For mRNA analyses, target gene data were normalized for levels of the housekeeping...
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Status of training program management of part time courses of TUAF basis for mangement regulation policies
... non-formal (Ined 2002) The European Commission (EC) (2001) Communication on Lifelong Learning: formal, non-formal and informal learning They placed non-formal learning in between formal and informal ... adult learning falls under non-formal learning; in others, most adult learning is formal Non-formal learning therefore gives some flexibility between formal and informal learning, which must be ... The broad framework for achieving this certification across both non-formal and informal learning is outlined in the Cedefop European guidelines for validating non-formal and informal learning;...
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Social factors as a basis for treatment
... evidence base It is unclear, therefore, which clubhouse elements are effective and which standards are necessary for success 175 Social factors as a basis for treatment Conclusion Social factors ... States 173 Social factors as a basis for treatment A jail diversion programme People suffering from both substance abuse disorder and serious mental illness form a significant component of the ... 2000) The lack of formal income support for many people with mental illness increases the incentive to make use of the work opportunities, which are often quite comprehensive, for people with mental...
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Tài liệu Lecture 14: The Theoretical Basis for Data Communication: pptx
... measurement The decibel level indicates the relationship of one power level to another The formula for calculating decibel is : dB = 10 log Po/Pi = 10 log 1000mW/10mW = 10 log 100 = 10 x =20 ... power levels such as 10 thousandth of a watt (10 mW) The milliwatt is the unit of measure used for power in telecommunications circuits Rather than absolute measure of power, we often concerned ... comparison of one power level to another Such as the output power of an amplifier (RF or AF) is 1000 mW for an input power of 10 mW We can say this whole this output with one unit, such as the output...
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Tài liệu Báo cáo khoa học: Properties of ecdysteroid receptors from diverse insect species in a heterologous cell culture system – a basis for screening novel insecticidal candidates docx
... equalized for gel loading on the basis of b-galactosidase reporter gene activity Densitometry readings for individual signals are adjusted relative to DmEcRB2 (equals 1.0) Immunoblots were also performed ... ecdysteroid receptors from two insect species for which relevant biochemical and in vivo information exists The comparative profiles demonstrate an approach for developing a screening system to identify ... characteristics seen among ecdysteroid receptors from various insect species suggests a basis for identifying and screening for compounds that perturb normal receptor function [12,13,15,16] Ecdysteroid...
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Tài liệu Báo cáo khoa học: Structural basis for cyclodextrin recognition by Thermoactinomyces vulgaris cyclo⁄maltodextrin-binding protein ppt
... [11,15] A common drastic conformational change is found in this protein family, which participates in switching from an open form to a closed form [16] In EcoMBP, the closed form has been observed ... defined in terms not of the affinities for sugars but of whether the protein adopts the open form or the closed form TvuCMBP–c-CD complex is seen as the closed form (Fig 2A,B), and this structure ... shows the high affinities for not only CDs but also higher maltooligosaccharides It is impossible to determine, however, whether TvuCMBP adopts the open form or the closed form with the sugars listed...
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Tài liệu Báo cáo khoa học: Kinetic basis for linking the first two enzymes of chlorophyll biosynthesis doc
... intermediate Rate constant for decay of intermediate Lag phase preceding MgDME product formation Magnitude of burst in product formation Rate constant for MgDME product formationa a ChlM ChlM + ... kinetic parameters for Synechocystis ChlM, and the effects of the magnesium chelatase ChlH subunit (rate constants refer to Scheme 1) Parameter MgD K app Rate constant for formation of catalytic ... chromatograms for each timepoint (B) The evolution ⁄ depletion of the putative intermediate was followed by integrating the peaks at 12.7 on the HPLC chromatograms for each timepoint The data for the...
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Đề tài " A five element basis for the uncountable linear orders " doc
... strong form of the axiom of infinity (the existence of a supercompact cardinal) that the class of uncountable linear orders has a five element basis In fact such a basis follows from the Proper Forcing ... C and C ∗ form a five element basis for the uncountable linear orders whenever X is a set of reals of cardinality ℵ1 and C is a Countryman line Notice that by our observations such a basis is necessarily ... in [24] serve as good concise references on the subject See [15] for information on the Mapping Reflection Principle For basic forcing technology, the reader is referred to [11] and [14] Part...
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Báo cáo khoa học: Investigations into the ability of an oblique a-helical template to provide the basis for design of an antimicrobial anionic amphiphilic peptide pot
... at 15 minute intervals for h and then hourly intervals for h At each time interval, samples were surface-spread on to nutrient agar plates, which were incubated at 37 C for 12 h As a FEBS Journal ... user-friendly software for the analysis of aminoacid sequences Biotechniques 26, 11701172 Keller RC, Killian JA & de Kruijff B (1992) Anionic phospholipids are essential for alpha-helix formation of the ... (GLFGAIAGFIENG), which is key to its structure and underlying hydrophobicity gradient, was used as a basis for the hydrophobicity gradient of the AP1 peptide, thereby giving these peptides 62% sequence...
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Global Guidance PrinciPles for life cycle assessment databases: A Basis for Greener Processes and Products ppt
... were prepared for each area, and previously published information was extracưed into t a database for use in preparing these papers and for consultation during the workshop Topics for the work ... sufficient basis not to provide the information at the unit process level, we strongly recommend that other information be included in the aggregated process dataset, for example, information ... 99 5.2 Additional Database Properties for Geographical and Temporal Information 99 5.2.1 Geographic information 99 5.2.2 Temporal Information 100 5.3 Additional...
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Báo cáo khoa học: The structural basis for catalytic function of GMD and RMD, two closely related enzymes from the GDP-D-rhamnose biosynthesis pathway pdf
... before each run by washing with 0.2 m sodium hydroxide, water, and running buffer, each for Samples were introduced by pressure injection for s (for reaction composition analysis) or 24 s (for ... GDP-6-deoxy-d-lyxo-hexos-4-ulose, a GMD reaction was performed for h, the enzyme was removed by filtration, and then enzyme and cofactor for the second reaction were added To determine the optimal pH for enzyme-catalyzed reactions, ... nearly identical to those reported for GDP-d-Rha [5] On the basis of these NMR findings, compound D was concluded to be GDP-a-d-Rha These results for His6-RMDPa therefore confirm that this enzyme is...
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Báo cáo khoa học: Structural basis for the erythro-stereospecificity of the L-arginine oxygenase VioC in viomycin biosynthesis docx
... the Research Collaboratory for Structural Bioinformatics under accession numbers 2WBO for the substrate•tartrate•iron complex, 2WBQ for the complex with hArg, and 2WBP for the complex with hArg•succinate•iron ... substrate-binding mode results from conformational control of the enzyme on the side chain rotamer of the bound substrate For example, in AsnO, a trans conformer is selected for the v1 torsion angle of ... revealed that iron is activated for dioxygen binding by substrate coordination next to the preformed Fe(II)• aKG•enzyme complex (Fig 2) The Fe(II)•dioxygen adduct forms a Fe(IV)-peroxo or a Fe(III)-superoxo...
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Báo cáo khoa học: Molecular basis for specificities of reactivating factors for adenosylcobalamin-dependent diol and glycerol dehydratases pptx
... structure, were 120 500 m)1Æcm)1 for diol dehydratase [35], 112 100 m)1Æcm)1 for glycerol dehydratase [49], 58 140 m)1Æcm)1 for DDR [35], and 86 500 m)1Æcm)1 for GDR [37], respectively Assays ... more specific for the dehydratase partner than DDR, and that a large subunit of the reactivating factors principally determines the specificity for a dehydratase [41]; the reason for this, however, ... dehydratase-bound CN-Cbl for free AdePeCbl – that is, GDR is more specific for glycerol dehydratase, the cognate dehydratase Specificities of reactivating factors in the complex formation with dehydratases...
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Báo cáo khoa học: Structural basis for recognition of Co2+ by RNA aptamers pot
... activity Conclusions The significance of Mg2+ for RNA stability, RNA catalysis and the regulation of gene expression is well established However, information concerning participation of other metal ... was performed on Biometra (Goettingen, Germany) UNO II ¨ thermocycler for six cycles (30 s at 93 °C, 30 s at 55 °C and at 72 °C) The double-stranded DNA was extracted with phenol ⁄ chloroform (1 ... Smolska for her excellent technical assistance We also thank the reviewers for their comments on the manuscript This work was supported by grant P04A 081 21, from the Polish Committee for Scientific...
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Food and health in Europe: a new basis for action pdf
... price differentials between foods should be studied and monitored When appropriate, researchers can feed this information into the formulas needed for legislation on minimum income, standards for ... Food and health in Europe: a new basis for action Summary ISBN 92 890 1364 The Regional Office for Europe of the World Health Organization welcomes requests for permission to reproduce or translate ... book provides the scientific evidence for national action plans and WHO’s First Food and Nutrition Action Plan for the European Region It provides information for the use of health professionals,...
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Báo cáo Y học: Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant doc
... The ˚ mean temperature factors was typically 55 A2 for all atoms, ˚ 30–60 A2 for the inhibitor atoms and lining residues The temperature factors for K103 and N103 atoms were in ˚ the range of 50–60 ... within subnanomolar range for all three inhibitors PNU142721 and MSC194 show a 3–10-fold reduction in efficacy for the K103N mutant The effect of the mutation is more pronounced for Efavirenz where ... binding mode for Efavirenz as observed for PNU142721 and MSC194 In addition, the Efavirenz complexes superimpose well with the structures of PNU142721 and MSC194 Thus, the reasons for resistance,...
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Báo cáo khoa học: Structural basis for substrate recognition by Erwinia chrysanthemi GH30 glucuronoxylanase potx
... to present a hypothesis for the basis of substrate recognition in this group of so-called ‘appendage-dependent xylanases’ [11] Examination of the structure of XynA [14] for the presence of aromatic ... where Ii (hkl) is the intensity measurement for the ith observation of reflection hkl and ÆI(hkl)æ is the average intensity for multiple measurements for this reflection P P R = ||Fobs| ) |Fcalc|| ... Imidazole ring Imidazole ring optimum of the enzyme [14] Similar calculations were performed for its three analogs For the first one, b-dxylopyranosyl-(1 fi 4)-[4-O-methyl-a-d-xylopyranosyl(1 fi 2)]-b-d-xylopyranosyl-(1...
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Báo cáo khoa học: Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin ppt
... The second conformation of the side chain of Glu221, which also adopts two conformations but not correlated with the anomeric form of the bound mannose is shown in dark green site for subunit B ... structural information is complemented by thermodynamic parameters of binding determined by means of isothermal titration calorimetry for the above-mentioned complexes as well as other complexes for which ... first before binding to adjacent subsites will occur Thermodynamics of carbohydrate binding to PAL To complement our structural studies, the thermodynamic parameters for the binding to PAL for mannose,...
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Báo cáo khóa học: Acyl-CoA dehydrogenases and acyl-CoA oxidases Structural basis for mechanistic similarities and differences pot
... known in peroxisomes, ACO is protected from forming an electron-transfer complex with an ETF-like molecule, should one exist Therefore, the structural basis for ACO being an oxidase rather than a ... both of which are specific for C2-branched substrates, can tolerate a bulky residue (tyrosine in i2VD and leucine in iBD) at this position However, the structural basis for the C2-branched substrate ... required for the decarboxylation reaction Thus, Arg94 appears to be involved in the binding of the substrate and in the alignment of the glutaryl-CoA substrate for optimum orientation for the...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu