pharmacologic approaches to type 2 diabetes and obesity in children and adolescents
Probiotics as a novel approach to modulate incretins, insulin secretion and risk factors of type 2 diabetes and complications
... of insulin resistance and secretion in type diabetes In 20 10 about 28 5 million people were suffering from diabetes and this number is expected to increase to more than 550 million by the year 20 30 ... diagnosis of diabetes and is initially compensated by increased insulin secretion (Tabak et al., 20 09; Ferrannini et al., 20 05) T2D manifests when high insulin demand resulting from insulin resistance ... contribute to the development of insulin resistance and subsequently to type diabetes Adiposity contributes to T2D development in two aspects On one hand insulin resistance of adipose tissue insulin...
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RECENT ADVANCES IN THE PATHOGENESIS, PREVENTION AND MANAGEMENT OF TYPE 2 DIABETES AND ITS pptx
... 0.09 ± 0.03 cm2 in the MB, 0.0.7 ± 0. 02 cm2 in the UA, 0.18 ± 0.04 cm2 in the TA, and 0.05 ± 0.01 cm2 in the SA The CSAs in the controls were 0.08 ± 0. 02 cm2 in the MA, 0.07 ± 0. 02 cm2 in the MB, ... treat the important topic of diabetes and fibrinolysis, including evidence for plasminogen activator inhibitor-1 as a predictor of cardiovascular risk in type diabetes Yaturu and Mousa discuss ... the mean intensity of the image t* = and arg 1≦t＜L 2 max{σB (t)|σB = w1(μ1 –μT )2 + w2( 2 –μT )2} (6) 22 Recent Advances in the Pathogenesis, Prevention and Management of Type Diabetes and its Complications...
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Báo cáo khoa hoc:" Applying the Stages of Change model to Type 2 diabetes care in Trinidad: A randomised trial" pptx
... 1.0 (0. 02) 1.0 (0.04) 1.0 (0.05) * Body Mass Index (kg/m2) Plasma creatinine (mmol/l) Fasting Total Cholesterol (mg/dl) 21 4.3 (4.91) 21 4.4 (17.64) 23 2.7 (6.79) 21 7 .2 (8 .25 ) * Fasting Total Triglycerides ... income 24 (39) 19 (31) < $20 00.00 Duration as diabetic 16 (26 ) 21 (34) > $20 00.00 19 (31) 17 (28 ) 1-5 years 27 ( 42) 16 (26 ) 5-10 years 21 (34) 21 (34) > 10 years Existing co-morbid conditions 13 (21 ) ... income 20 (34) 24 (40) Occupation 25 (41) 29 (48) Savings (0) (3) Spouse 14 (23 ) 19 (31) Children who are employed (10) 12 (20 ) Other relative (2) (0) < $500.00 (3) (7) < $1000.00 Total monthly income...
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Aspects of carbohydrate quality and their relevance for risk markers of type 2 diabetes and related health outcomes
... acids and inflammatory markers in IR will be described in chapters 2. 2 .2 and 2. 2.3, respectively 15 THEORETICAL BACKGROUND 2. 2 .2 Obesity Obesity is considered a major risk factor for IR and T2D ... Dietary Glycemic Index and Glycemic Load 2. 1.4 Dietary Insulin Index and Insulin Load 2. 2 Risk markers of type diabetes mellitus and related health outcomes 2. 2.1 Type diabetes mellitus ... obese individuals [134], perhaps explaining the increased CVD risk among some obese individuals [135] Pro-inflammatory cytokines are able to inhibit insulin action in adipocytes via autocrine and...
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Tài liệu Báo cáo khoa học: Metabolic control of mitochondrial properties by adenine nucleotide translocator determines palmitoyl-CoA effects Implications for a mechanism linking obesity and type 2 diabetes pdf
... Grigiene J (20 02) Multiple effects of 2, 2,5,5-tetrachlorbiphenyl on oxidative phosphorylation in rat liver mitochondria Toxicol Sci 65, 22 0 22 7 FEBS Journal 27 3 (20 06) 528 8–53 02 ª 20 06 The Authors ... succinate oxidation); 2, QH2-oxidizing module, comprising cytochrome bc1 and cytochrome c oxidase; 3, proton leak module, comprising passive membrane permeability to protons and cation cycling; ... is in line with a mechanism we proposed to underlie the association between obesity and type diabetes [9, 12] However, owing to multiple interactions in living systems, it can be difficult to differentiate...
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Long-term Exposure to Traffic-related Air Pollution and Type 2 Diabetes Prevalence in a Cross-sectional Screening-study in the Netherlands pdf
... 20 02, 23 :599- 622 10 Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM: C-reactive protein, interleukin 6, and risk of developing type diabetes mellitus JAMA 20 01, 28 6: 327 -334 11 Ko K-P, Min ... ( 52% ) 3,619 (49%) Age (years) 50-55 2, 753 (34%) 96 (16%) 28 (13%) 2, 657 (36%) 55-60 1,795 (22 %) 110 (18%) 38 (18%) 1,685 (23 %) 60-65 1,446 (18%) 122 (20 %) 45 (21 %) 1, 324 (18%) ≥ 65 2, 024 (25 %) ... contributed to inconsistent findings For instance, the interquartile range for NO2-exposure in this study was only 2. 3 μg/m3, while in previous studies on air pollution and type diabetes [2, 3] this...
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Guide to Living with Diabetes Preventing and Treating Type 2 Diabetes— Essential Information You and Your Family Need to Know ppt
... 199 20 6 21 3 22 1 25 8 29 4 6'1" 144 151 159 166 174 1 82 189 197 20 4 21 2 21 9 22 7 26 5 3 02 6 '2" 148 155 163 171 179 186 194 20 2 21 0 21 8 22 5 23 3 27 2 311 6'3" 1 52 160 168 176 184 1 92 200 20 8 21 6 22 4 23 2 ... 22 4 23 2 24 0 27 9 319 6'4" 156 164 1 72 180 189 197 20 5 21 3 22 1 23 0 23 8 24 6 28 7 328 BMI 19 20 21 22 23 24 25 26 27 28 29 30 35 40 Key: Underweight (less than 18.5) Healthy weight (18.5 to 24 .9) Overweight ... the increased demand for insulin, as in type diabetes Insulin was discovered in 1 921 in Canada, and the first insulin preparations for treating diabetes were developed in 1 922 The discovery of insulin...
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Báo cáo y học: " Barriers and facilitators to evidence based care of type 2 diabetes patients: experiences of general practitioners participating to a quality improvement program" ppt
... Lipidol 20 02, 13:617- 623 23 24 25 26 27 28 29 30 Gaede P, Lund-Andersen H, Parving HH, Pedersen O: Effect of a multifactorial intervention on mortality in type diabetes N Engl J Med 20 08, 358:580-591 ... Barriers to initiating insulin therapy in patients with type diabetes mellitus in public-sector primary health care centres in Cape Town S Afr Med J 20 05, 95:798-8 02 Cook S, Drum ML, Kirchhoff AC, Jin ... reassurance by intonation and body language in order to disclose the very personal feelings and experiences of the interviewees The interviews took 30 to 45 minutes and were conducted individually...
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IMPAIRED CARDIOVASCULAR RESPONSES TO GLUCAGON-LIKE PEPTIDE 1 IN METABOLIC SYNDROME AND TYPE 2 DIABETES MELLITUS
... Program for enabling his integration into an outstanding community of educators, clinicians and scientists This work was supported by NIH grants HL0 922 45 (JDT), HL0 927 99 (KJM), and the Indiana University ... this ligand/receptor interaction increases PKA activity and insulin secretion in a glycemia-dependent manner (58, 59) GLP-1 (7-36) is also known to increase insulin sensitivity and reduce ... administered into the coronary circulation of isolated rat hearts, and administered intravenously in canines with heart failure However, this insulinomimetic effect occurred within 30 minutes in...
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Báo cáo y học: "A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes"
... Curr Opin Clin Nutr Metab Care 20 02, 5:551-559 14 Marette A: Mediators of cytokine-induced insulin resistance in obesity and other inflammatory settings Curr Opin Clin Nutr Metab Care 20 02, 5:377-383 ... 1.4 (0.9 to 4 .2) 1.3 (0.9 to 4.5) P = 0.106 Cholesterol (umol/l) 4.5 (2. 1 to 7.7) 4.8 (2. 0 to 9.7) 4.9 (2. 1 to 8.0) P = 0.146 Glucose levelsc 6.4 (2. 7 to 23 .5) 7.6 (3.8 to 23 .5) 5 .2 (2. 7 to 7.7) ... disease during pregnancy Jama 20 05, 29 4 :27 51 -27 57 49 Kim C, Newton KM, Knopp RH: Gestational diabetes and the incidence of type diabetes: a systematic review Diabetes Care 20 02, 25 :18 62- 1868 50...
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Báo cáo y học: "The association of meat intake and the risk of type 2 diabetes may be modified by body weight"
... meat intake, and the risk of type diabetes in women Arch Intern Med 20 04; 164 (20 ) :22 35 -22 40 Schulze MB, Manson JE, Willett WC, Hu FB Processed meat intake and incidence of Type diabetes in younger ... 2. 7 26 .2 23.6 14.0 24 .4 38.0 5.6 0.1 1.4 18.9 14.5 9.7 15.6 60 .2 9.1 0 .2 3.6 26 .1 19.8 12. 6 22 .3 45.3 6.4 0.7 1.6 21 .6 Int J Med Sci 20 06, 158 Table 2: Unprocessed meat intake and risk of type diabetes ... 1659.4 2. 8 2. 2 2. 2 2. 68 38.6 30.9 36.0 33.8 38.8 34.3 33.1 32. 3 23 .7 10.8 11.53 42. 3 30.6 15.5 36.1 34.3 21 .1 8.5 9.9 38.9 33.8 17.3 32. 7 31.8 22 .8 12. 6 18.4 38.3 29 .3 14.1 20 .2 38.8 24 .7 16.3...
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Effectiveness of PRECEDE model for health education on changes and level of control of HbA1c, blood pressure, lipids, and body mass index in patients with type 2 diabetes mellitus docx
... inhibitors Insulin 14 .2 (10.4-18) 14.4 (10.4-18.4) 0.94 Diuretics 27 .4 (22 .5- 32. 3) 23 .1 (18.3 -27 .9) 0 .23 Beta blockers 12. 9 (9 .2- 16.6) 9.7 (6.4-13.1) 0 .22 ACE inhibitors 30.6 (25 .5-35.7) 29 .1 (24 -34 .2) ... Control PRECEDE 12. 7 12. 3 12. 5 12. 3 0.90 -0 .2 0.85 SBP (
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TYPE 2 DIABETES - National clinical guideline for management in primary and secondary care (update) pdf
... control: insulin therapy Oral agent combination therapy with insulin Insulin therapy Insulin detemir Insulin delivery devices 125 130 146 146 12 12. 1 12. 2 12. 3 Blood pressure therapy Clinical introduction ... Guideline Development Group Acknowledgements Preface v vii viii DEVELOPMENT OF THE GUIDELINE 1.1 1 .2 1.3 1.4 2. 1 2. 2 2. 3 2. 4 2. 5 2. 6 2. 7 2. 8 2. 9 2. 10 3.1 3 .2 Introduction Background Definition ... adults and children , NICE clinical guideline no 43 (20 06) q Type diabetes: diagnosis and management of type diabetes in children, young people and adults’, NICE clinical guideline no 15 (20 04, to...
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báo cáo hóa học:" Is there a relationship between factor V Leiden and type 2 diabetes?" doc
... Tofler GH, Singer DE, MurphySheehy PM, Lipinska I, D'Agostino RB, Wilson PW: Hyperinsulinemia, hyperglycemia, and impaired hemostasis: the Framingham Offspring Study JAMA 20 00, 28 3 (2) :22 1 -22 8 Ceriello ... trend to develop type diabetes is related to a multivariate genegene interaction and gene-enviromental interaction Conclusion So, our data pointed out again an interesting aspect of the linking ... diabetes is recognised as one of the more common risk factor for atherothrombosis [2] Both type diabetes (i.e insulin dependent) and type diabetes (i.e not-insulin dependent) are associated to...
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báo cáo hóa học: " A comparison of EQ-5D index scores using the UK, US, and Japan preference weights in a Thai sample with type 2 diabetes" pdf
... 6.53 4.10 300,000 2. 43 123 ,457 1 .23 6.94 4.40 300,000 2. 54 118,110 5.51 6.68 4 .21 300,000 2. 47 121 ,457 2. 83 6. 62 4.17 300,000 2. 45 122 ,150 2. 28 7.05 4.49 300,000 2. 56 117,096 6. 32 Decision tree ... Literature review and proposed guidelines J Clin Epidemiol 1993, 46:1417-14 32 16 17 18 19 20 21 22 23 24 25 26 Kaplan RM, Feeny D, Revicki DA: Methods for assessing relative importance in preference ... analyzing the data, and writing the article RC contributed to analyzing the data and the interpretation of the results RS contributed to analyzing and collecting the data All authors have read and...
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báo cáo hóa học: " Fatness and fitness: how do they influence health-related quality of life in type 2 diabetes mellitus?" docx
... control in type diabetes: a randomized trial Ann Intern Med 20 07, 147(6):357-69 Hamdy O, Goodyear LJ, Horton ES: Diet and exercise in type diabetes mellitus Endocrinol Metab Clin North Am 20 01, ... of type diabetes with HRQOL Model added fitness to Model to test its influence on the type diabetes- HRQOL association The final model (model 4) added both fatness and fitness to model to examine ... mg/dL Mean hemoglobin A1c (SD), % 63.8 (5.6) 46 .2 85.7 38 .2 (9 .2) 24 .1 (5.1) 21 5 .2 (37.5) N/A 56.9 (5.9) 63.3 60 .2 36.0 (7.1) 21 .2 (5.1) 178.8 (40 .2) 6.6 (1.5) < 0.001 0.0 12 < 0.001 0.068 < 0.001...
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báo cáo hóa học: " Additional impact of concomitant hypertension and osteoarthritis on quality of life among patients with type 2 diabetes in primary care in Germany – a cross-sectional survey" doc
... (18.84) 46.93* (19. 42) 77.69 (23 . 82) 81.47 (22 . 52) 71.60* (26 .99) 74 .25 (26 .78) 66.83 (43.91) 82. 52 (35.08) 62. 45 (44.46) 68.06 (44. 92) 69 .21 (21 .25 ) 72. 79 (17.88) 65.68 (18.33) 66.35 (20 .83) 43.45 ... 72. 21 (40 .26 ) 41.46* (44.56) 45.50* (45. 12) 66.94 (30 .26 ) 72. 89 (27 .01) 44 .21 *** (21 .54) 44.60*** (23 .99) 55. 82 (20 .17) 57.79 (17.15) 50.46* (17.06) 49.13** (18. 02) 52. 09 (23 .78) 58.33 (21 .05) 47.98 ... and osteoarthritis (n = 97) Diabetes, hypertension and osteoarthritis (n = 27 1) RP BP GH VT SF RE MH PCS MCS 65.77 (30.44) 70. 02 (26 .14) 49.99 *** (27 .90) 53.08 *** (28 .04) 62. 42 (44 .20 ) 72. 21...
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báo cáo hóa học: " Development and validation of the insulin treatment appraisal scale (ITAS) in patients with type 2 diabetes" docx
... I enjoy 12 Insulin means my health will deteriorate 13 Injecting insulin is embarrassing 14 Injecting insulin is painful 15 It is difficult to always inject insulin correctly 16 Insulin makes ... needle injection Insulin will increase the risk of hypoglycaemia Insulin will improve health Insulin will cause weight gain 10 Insulin will be demanding to administer 11 Insulin means I have to give ... diabetes The scope of the problem Diabetes Care 20 05, 28 :25 43 -25 45 Meece J: Dispelling myths and removing barriers about insulin in type diabetes Diabetes Educator 20 06, 32( 1):9S-18S Brod M, Skovlund...
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báo cáo hóa học:" Factors associated with psychological and behavioral functioning in people with type 2 diabetes living in France" pptx
... 0.98 1 .22 0. 42 0.008 - 2. 16 1.10 0.05 0. 02 - 2. 20 1 .28 < 001 0.09 < 001 0.10 Insulin - 9.49 1 .23 < 001 - 8.54 1.94 < 001 - 3.35 1.61 0.04 Insulin & OHAs - 8.79 1. 32 < 001 - 2. 43 1.97 0 .22 - 1.64 ... life in type diabetes Diabetologia 20 06, 49:1489-1497 Boini et al Health and Quality of Life Outcomes 20 10, 8: 124 http://www.hqlo.com/content/8/1/ 124 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 ... [http://www.invs.sante.fr/ beh /20 02/ 20 _21 /beh _20 _21 _20 02. pdf] Nazimek-Siewniak B, Moczulski D, Grzeszczak W: Risk of macrovascular and microvascular complications in Type diabetes: results of longitudinal...
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